{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:11:39Z","timestamp":1791425499946,"version":"4.3.3"},"reference-count":42,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.nut.2009.04.014","type":"journal-article","created":{"date-parts":[[2009,8,9]],"date-time":"2009-08-09T08:20:07Z","timestamp":1249806007000},"page":"305-311","source":"Crossref","is-referenced-by-count":84,"title":["Fructo-oligosaccharides enhance the mineral absorption and counteract the adverse effects of phytic acid in mice"],"prefix":"10.1016","volume":"26","author":[{"given":"Yu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu-e","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Xia","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2009.04.014_bib1","series-title":"Functional foods-designer foods, pharma foods, nutraceuticals","first-page":"183","article-title":"Health functionality of food components","author":"Stark","year":"1994"},{"key":"10.1016\/j.nut.2009.04.014_bib2","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1079\/NRR200479","article-title":"Dietary modulation of the human colonic microbiota: updating the concept of prebiotics","volume":"17","author":"Gibson","year":"2004","journal-title":"Nutr Res Rev"},{"issue":"suppl","key":"10.1016\/j.nut.2009.04.014_bib3","first-page":"1147","article-title":"Functional food science and gastrointestinal physiology and function","volume":"80","author":"Salminen","year":"1998","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib4","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1006\/fmic.1994.1055","article-title":"Bifidogenic properties of different types of fructooligosaccharides","volume":"11","author":"Gibson","year":"1994","journal-title":"Food Microbiol"},{"key":"10.1016\/j.nut.2009.04.014_bib5","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1136\/bmj.318.7189.999","article-title":"Probiotics and prebiotics: can regulating the activities of intestinal bacteria benefit health?","volume":"318","author":"Macfarlane","year":"1999","journal-title":"Br Med J"},{"key":"10.1016\/j.nut.2009.04.014_bib6","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/ajcn\/61.4.938S","article-title":"Gastrointestinal effects of food carbohydrate","volume":"61","author":"Cummings","year":"1995","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib7","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1017\/S0007114599000252","article-title":"Functional food properties of non-digestible oligosaccharides: a consensus report for the ENDO project (DGXII AIRII-CT94-1095)","volume":"81","author":"Van Loo","year":"1999","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib8","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/j.1601-0825.2005.01129.x","article-title":"Fructooligosaccharide consumption improves the decreased dentin formation and mandibular defects following gastrectomy in rats","volume":"11","author":"Morohashi","year":"2005","journal-title":"Oral Dis"},{"key":"10.1016\/j.nut.2009.04.014_bib9","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1080\/07315724.2005.10719440","article-title":"Influence of short-chain fructo-oligosaccharides (sc-FOS) on absorption of Cu, Zn, and Se in healthy postmenopausal women","volume":"24","author":"Ducros","year":"2005","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib10","doi-asserted-by":"crossref","first-page":"426","DOI":"10.3177\/jnsv.51.426","article-title":"Expression of calbindin-D9k, VDR and Cdx-2 messenger RNA in the process by which fructooligosaccharides increase calcium absorption in rats","volume":"51","author":"Fukushima","year":"2005","journal-title":"J Nutr Sci Vitaminol"},{"key":"10.1016\/j.nut.2009.04.014_bib11","first-page":"1639","article-title":"Prevention of osteoporosis by foods and dietary supplements. The effect of fructooligosaccharides (FOS) on the calcium absorption and bone","volume":"16","author":"Ohta","year":"2006","journal-title":"Clin Calcium"},{"key":"10.1016\/j.nut.2009.04.014_bib12","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/0271-5317(96)00043-7","article-title":"Fructooligosaccharides stimulate the absorption of magnesium from the hindgut in rats","volume":"16","author":"Baba","year":"1996","journal-title":"Nutr Res"},{"key":"10.1016\/j.nut.2009.04.014_bib13","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1024\/0300-9831.69.5.348","article-title":"Dietary heme iron does not prevent postgastrectomy anemia but fructooligosaccharides improve bioavailability of heme iron in rats","volume":"69","author":"Ohta","year":"1999","journal-title":"Int J Vitam Nutr Res"},{"key":"10.1016\/j.nut.2009.04.014_bib14","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3177\/jnsv.41.281","article-title":"Effects of fructooligosaccharides on the absorption of iron, calcium and magnesium in iron-deficient anemic rats","volume":"41","author":"Ohta","year":"1995","journal-title":"J Nutr Sci Vitaminol"},{"key":"10.1016\/j.nut.2009.04.014_bib15","first-page":"316","article-title":"Effects of fructooligosaccharides on the absorption of magnesium and calcium by cecectomized rats","volume":"64","author":"Ohta","year":"1994","journal-title":"Int J Vitam Nutr Res"},{"key":"10.1016\/j.nut.2009.04.014_bib16","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.nut.2008.08.002","article-title":"Effects of dietary lipid composition and inulin-type fructans on mineral bioavailability in growing rats","volume":"25","author":"Lobo","year":"2009","journal-title":"Nutrition"},{"key":"10.1016\/j.nut.2009.04.014_bib17","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0958-6946(98)00071-5","article-title":"An overview of probiotics, prebiotics and synbiotics in the functional food concept: perspectives and future strategies","volume":"8","author":"Ziemer","year":"1998","journal-title":"Int Dairy J"},{"key":"10.1016\/j.nut.2009.04.014_bib18","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1093\/jn\/127.1.130","article-title":"Selected indigestible oligosaccharides affect large bowel mass, cecal and fecal short-chain fatty acids, pH and microflora in rats","volume":"127","author":"Campbell","year":"1997","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib19","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1079\/BJN2001403","article-title":"Oligofructose and long-chain inulin: influence on the gut microbial ecology of rats associated with the human faecal flora","volume":"86","author":"Kleessen","year":"2001","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib20","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S1360-1385(01)02104-5","article-title":"Seeds for a better future: \u2018Low phytate\u2019 grains help to overcome malnutrition and reduce pollution","volume":"6","author":"Raboy","year":"2001","journal-title":"Trends Plant Sci"},{"key":"10.1016\/j.nut.2009.04.014_bib21","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0955-2863(99)00036-4","article-title":"Effects of soluble corn bran arabinoxylans on cecal digestion, lipid metabolism, and mineral balance (Ca, Mg) in rats","volume":"10","author":"Hubert","year":"1999","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.nut.2009.04.014_bib22","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0271-5317(99)00146-3","article-title":"Resistant starch improves mineral assimilation in rats adapted to a wheat bran diet","volume":"20","author":"Lopez","year":"2000","journal-title":"Nutr Res"},{"key":"10.1016\/j.nut.2009.04.014_bib23","series-title":"Nutritional biochemistry","first-page":"761","article-title":"Inorganic nutrients","author":"Brody","year":"1999"},{"key":"10.1016\/j.nut.2009.04.014_bib24","first-page":"106","article-title":"Preliminary report of decreased serum magnesium in postmenopausal osteoporosis","volume":"8","author":"Reginster","year":"1989","journal-title":"Magnesium"},{"key":"10.1016\/j.nut.2009.04.014_bib25","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1359\/jbmr.1998.13.4.749","article-title":"Magnesium deficiency: a cause of heterogeneous disease in humans","volume":"13","author":"Rude","year":"1998","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.nut.2009.04.014_bib26","series-title":"Supporting paper of the international conference on nutrition","article-title":"Prevention micronutrient deficiencies. In: ICN: fact sheet number one","author":"FAO\/WHO","year":"1992"},{"key":"10.1016\/j.nut.2009.04.014_bib27","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1093\/ajcn\/75.6.1062","article-title":"Effect of supplemental zinc on the growth and serum zinc concentrations of prepubertal children: a meta-analysis of randomized controlled trials","volume":"75","author":"Brown","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib28","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1001\/archpedi.1991.02160080029016","article-title":"Zn deficiency\u2014a public health problem?","volume":"145","author":"Sandstead","year":"1991","journal-title":"Am J Dis Child"},{"key":"10.1016\/j.nut.2009.04.014_bib29","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1002\/jsfa.1133","article-title":"Effect of fructooligosaccharides on nutritional parameters and mineral bioavailability in rats","volume":"82","author":"Gudiel-Urabano","year":"2002","journal-title":"J Sci Food Agr"},{"key":"10.1016\/j.nut.2009.04.014_bib30","first-page":"3599","article-title":"Dietary chicory inulin increases whole-body bone mineral density in growing male rats","volume":"132","author":"Roberfroid","year":"2002","journal-title":"J\u00a0Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib31","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1079\/BJN2002661","article-title":"Effect of oligofructose or dietary calcium on repeated calcium and phosphorus balances, bone mineralization and trabecular structure in ovariectomized rats","volume":"88","author":"Scholz-Ahrens","year":"2002","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib32","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1254\/jjp.82.54","article-title":"Dietary fructooligosaccharides prevented a reduction of cortical and trabecular bone following by the total gastrectomy in rats","volume":"84","author":"Morohashi","year":"2000","journal-title":"Jpn J Pharmacol"},{"key":"10.1016\/j.nut.2009.04.014_bib33","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1007\/s00394-003-0390-x","article-title":"Effects of inulin-type fructans of different chain length and type of branching on intestinal absorption and balance of calcium and magnesium in rats","volume":"42","author":"Charles","year":"2003","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib34","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1093\/jn\/130.7.1792","article-title":"Fructooligosaccharide consumption enhances femoral bone volume and mineral concentrations in rats","volume":"130","author":"Takahara","year":"2000","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib35","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1016\/0271-5317(96)00101-7","article-title":"Availability of minerals in rats and pigs\u00a0fed non-purified diets containing inulin","volume":"16","author":"Vanhoof","year":"1996","journal-title":"Nutr Res"},{"key":"10.1016\/j.nut.2009.04.014_bib36","doi-asserted-by":"crossref","first-page":"2513S","DOI":"10.1093\/jn\/137.11.2513S","article-title":"Inulin and oligofructose and mineral metabolism: the evidence from animal trials","volume":"137","author":"Katharina","year":"2007","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2009.04.014_bib37","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/BF02925452","article-title":"Usefulness of the dietary phytic acid\/zinc molar ratio as an index of zinc bioavailability to rats and humans","volume":"19","author":"Morris","year":"1989","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.nut.2009.04.014_bib38","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1016\/j.foodchem.2005.11.018","article-title":"Content of phytic acid and its mole ratio to zinc in flour and breads consumed in Tabriz, Iran","volume":"100","author":"Gargari","year":"2007","journal-title":"Food Chem"},{"key":"10.1016\/j.nut.2009.04.014_bib39","first-page":"1005","article-title":"The effects of undigestible fructooligosaccharides on intestinal microflora and various physiological functions on human health","volume":"270","author":"Hidaka","year":"1990","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.nut.2009.04.014_bib40","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1016\/S0271-5317(00)00274-8","article-title":"Effects of fructooligosaccharide on bowel function and indicators of nutritional status in constipation elderly men","volume":"20","author":"Chen","year":"2000","journal-title":"Nutr Res"},{"key":"10.1016\/j.nut.2009.04.014_bib41","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S0955-2863(00)00109-1","article-title":"Fructooligosaccharides enhance mineral apparent absorption and counteract the deleterious effects of phytic acid on mineral homeostasis in rats","volume":"11","author":"Lopez","year":"2000","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.nut.2009.04.014_bib42","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1016\/j.foodchem.2008.02.064","article-title":"Robert Nout MJ, Hamer RJ. Effects of soaking, germination and fermentation on phytic acid, total and in vitro soluble zinc in brown rice","volume":"110","author":"Liang","year":"2008","journal-title":"Food Chem"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900709001890?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900709001890?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,21]],"date-time":"2019-05-21T22:49:06Z","timestamp":1558478946000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900709001890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0899900709001890"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2009.04.014","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]}}}