{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T12:15:15Z","timestamp":1788869715826,"version":"build-2803163510"},"reference-count":64,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.nut.2010.10.017","type":"journal-article","created":{"date-parts":[[2011,3,7]],"date-time":"2011-03-07T16:08:28Z","timestamp":1299514108000},"page":"925-930","source":"Crossref","is-referenced-by-count":34,"title":["Physiologic changes in homocysteine metabolism in pregnancy: A longitudinal study in Spain"],"prefix":"10.1016","volume":"27","author":[{"given":"Natalia","family":"\u00dabeda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia","family":"Reyes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Gonz\u00e1lez-Medina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Alonso-Aperte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregorio","family":"Varela-Moreiras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2010.10.017_bib1","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/j.1471-0528.1964.tb04317.x","article-title":"The role of folic acid in pregnancy with particular reference to anaemia, abruption and abortion","volume":"71","author":"Hibbard","year":"1964","journal-title":"J Obstet Gynaecol Br Commonw"},{"key":"10.1016\/j.nut.2010.10.017_bib2","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0140-6736(91)90133-A","article-title":"Prevention of neural tube defects: results of the Medical Research Council Vitamin Study","volume":"338","year":"1991","journal-title":"Lancet"},{"key":"10.1016\/j.nut.2010.10.017_bib3","doi-asserted-by":"crossref","first-page":"1832","DOI":"10.1056\/NEJM199212243272602","article-title":"Prevention of the first occurrence of neural-tube defects by periconceptional vitamin supplementation","volume":"327","author":"Czeizel","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nut.2010.10.017_bib4","first-page":"8781","article-title":"Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Final rule","volume":"61","year":"1996","journal-title":"Fed Regist"},{"key":"10.1016\/j.nut.2010.10.017_bib5","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1146\/annurev.nutr.19.1.217","article-title":"Homocysteine metabolism","volume":"19","author":"Selhub","year":"1999","journal-title":"Annu Rev Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib6","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/ajcn\/73.3.499","article-title":"Populations determinants of homocysteine","volume":"73","author":"Vollset","year":"2001","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib7","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1521-6934(03)00009-9","article-title":"Homocysteine and pregnancy","volume":"17","author":"Hague","year":"2003","journal-title":"Best Pract Res Clin Obstet Gynecol"},{"key":"10.1016\/j.nut.2010.10.017_bib8","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1136\/bmj.316.7135.894","article-title":"Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomised trials","volume":"316","year":"1998","journal-title":"BMJ"},{"key":"10.1016\/j.nut.2010.10.017_bib9","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1161\/01.CIR.98.23.2520","article-title":"Common methylentetrahydrofolate reductase gene mutation leads to hyperhomocysteinemia but not to vascular disease. The result of a meta-analysis","volume":"98","author":"Brattstrom","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.nut.2010.10.017_bib10","first-page":"377","article-title":"Decreased serum homocysteine in pregnancy","volume":"30","author":"Anderson","year":"1992","journal-title":"Eur J Clin Chem Clin Biochem"},{"key":"10.1016\/j.nut.2010.10.017_bib11","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/S0002-9378(99)70269-3","article-title":"Changes in homocysteine levels during normal pregnancy","volume":"180","author":"Walker","year":"1999","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.nut.2010.10.017_bib12","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1079\/BJN2000209","article-title":"Longitudinal vitamin and homocysteine levels in normal pregnancy","volume":"85","author":"Cikot","year":"2001","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib13","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1093\/ajcn\/76.3.614","article-title":"The pregnancy-related decrease in fasting plasma homocysteine is not explained by folic acid supplementation, hemodilution, or a decrease in albumin in a longitudinal study","volume":"76","author":"Murphy","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib14","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1056\/NEJM199101173240315","article-title":"Neural tube defects and derangement of homocysteine metabolism","volume":"324","author":"Steegers-Theunissen","year":"1991","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nut.2010.10.017_bib15","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0140-6736(95)90165-5","article-title":"Homocysteine metabolism in pregnancies complicated by neural-tube defects","volume":"345","author":"Mills","year":"1995","journal-title":"Lancet"},{"key":"10.1016\/j.nut.2010.10.017_bib16","doi-asserted-by":"crossref","first-page":"15227","DOI":"10.1073\/pnas.93.26.15227","article-title":"Homocysteine induces congenital defects on the heart and neural tube defect: effect of folic acid","volume":"93","author":"Rosenquist","year":"1995","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.nut.2010.10.017_bib17","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0029-7844(99)00610-9","article-title":"Homocysteine and folate levels as risk factors for recurrent early pregnancy loss","volume":"95","author":"Nelen","year":"2002","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.nut.2010.10.017_bib18","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1111\/j.1471-0528.2000.tb13341.x","article-title":"Hyperhomocysteinemia and other thrombotic risk factors in women with placental vasculopathy","volume":"107","author":"Van der Molen","year":"2002","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.nut.2010.10.017_bib19","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1093\/ajcn\/71.4.962","article-title":"Plasma total homocysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine study","volume":"71","author":"Vollset","year":"2000","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib20","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1093\/ajcn\/76.1.180","article-title":"Methylenetetrahydrofolate reductase 677CT genotype modulates homocysteine responses to a folate-rich diet or a low-dose folic acid supplement: a randomized controlled trial","volume":"76","author":"Ashfield-Watt","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib21","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/sj.ejcn.1601729","article-title":"Effects of the interaction between the C677T 5,10-methylenetetrahydrofolate reductase polymorphism and serum B vitamins on homocysteine levels in pregnant women","volume":"58","author":"Kim","year":"2004","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib22","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1373\/clinchem.2004.035709","article-title":"Homocysteine and folate in pregnancy","volume":"50","author":"Ueland","year":"2004","journal-title":"Clin Chem"},{"issue":"suppl 1","key":"10.1016\/j.nut.2010.10.017_bib23","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1177\/15648265080292S112","article-title":"Gene\u2013nutrient interactions: importance of folic acid and vitamin B12 during early embryogenesis","volume":"29","author":"Finnell","year":"2008","journal-title":"Food Nutr Bull"},{"key":"10.1016\/j.nut.2010.10.017_bib24","first-page":"50","article-title":"Curvas de desarrollo fetal de los reci\u00e9n nacidos en el Hospital de Cruces (Vizcaya)","volume":"44","author":"Delgado Beltr\u00e1n","year":"1996","journal-title":"An Esp Pediatr"},{"key":"10.1016\/j.nut.2010.10.017_bib25","doi-asserted-by":"crossref","unstructured":"American Diabetes Association. Gestational diabetes mellitus. Diabetes Care 2002;25(suppl 1):S94\u2013S96.","DOI":"10.2337\/diacare.25.2007.S94"},{"key":"10.1016\/j.nut.2010.10.017_bib26","unstructured":"Metzger BE, Coustan DR. Summary and recommendations of the Fourth International Workshop\u2013Conference on Gestational Diabetes Mellitus. The organizing committee. Diabetes Care 1998;21(suppl 2):B161\u20137."},{"key":"10.1016\/j.nut.2010.10.017_bib27","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/ng0595-111","article-title":"A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase","volume":"10","author":"Frosst","year":"1995","journal-title":"Nat Genet"},{"key":"10.1016\/j.nut.2010.10.017_bib28","series-title":"Tablas de composici\u00f3n de alimentos","author":"Moreiras","year":"2008"},{"issue":"suppl 1","key":"10.1016\/j.nut.2010.10.017_bib29","first-page":"34","article-title":"Association between estradiol and homocysteine fluctuations during pregnancy","volume":"26","author":"Murphy","year":"2003","journal-title":"J\u00a0Inherit Metab Dis"},{"key":"10.1016\/j.nut.2010.10.017_bib30","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1373\/clinchem.2004.032698","article-title":"Homocysteine is lower in the third trimester of pregnancy in women with enhanced folate status from continued folic acid supplementation","volume":"51","author":"Holmes","year":"2005","journal-title":"Clin Chem"},{"key":"10.1016\/j.nut.2010.10.017_bib31","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1111\/j.1471-0528.2008.01963.x","article-title":"The maternal Mediterranean dietary pattern is associated with a reduced risk of spina bifida in the offspring","volume":"116","author":"Vujkovic","year":"2009","journal-title":"Int J Obstet Gynaecol"},{"key":"10.1016\/j.nut.2010.10.017_bib32","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1373\/clinchem.2004.032904","article-title":"Maternal homocysteine before conception and throughout pregnancy predicts fetal homocysteine and birth weight","volume":"50","author":"Murphy","year":"2004","journal-title":"Clin Chem"},{"key":"10.1016\/j.nut.2010.10.017_bib33","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1093\/jn\/137.8.1863","article-title":"Longitudinal study of the effect of pregnancy on maternal and fetal cobalamin status in healthy women and their offspring","volume":"137","author":"Murphy","year":"2007","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib34","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0301-2115(02)00367-6","article-title":"Plasma total homocysteine in uncomplicated pregnancy and in preeclampsia","volume":"108","author":"L\u00f3pez-Quesada","year":"2003","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.nut.2010.10.017_bib35","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ejogrb.2004.08.008","article-title":"Polymorphisms of genes envolved in homocysteine metabolism in preeclampsia and in uncomplicated pregnancies","volume":"120","author":"Also-Rallo","year":"2005","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"10.1016\/j.nut.2010.10.017_bib36","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1056\/NEJM199905133401901","article-title":"The effect of folic acid fortification on plasma folate and total homocysteine concentrations","volume":"340","author":"Jacques","year":"1999","journal-title":"N\u00a0Eng J Med"},{"key":"10.1016\/j.nut.2010.10.017_bib37","doi-asserted-by":"crossref","first-page":"3277","DOI":"10.1093\/jn\/131.12.3277","article-title":"Folic acid fortification increases red blood cell folate concentrations in the Framingham study","volume":"131","author":"Choumenkovitch","year":"2001","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib38","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ejogrb.2003.12.009","article-title":"Awareness of the use of folic acid to prevent neural tube defects in a Mediterranean area","volume":"115","author":"Coll","year":"2005","journal-title":"Eur J Obstet Reprod Biol"},{"key":"10.1016\/j.nut.2010.10.017_bib39","doi-asserted-by":"crossref","first-page":"1383","DOI":"10.1093\/ajcn\/81.6.1383","article-title":"Plasma choline and betaine and their relation to plasma\u00a0homocysteine in normal pregnancy","volume":"81","author":"Velzing-Aarts","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib40","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1093\/ajcn\/87.2.391","article-title":"Homocysteine concentration, related B vitamins, and betaine in pregnant women recruited to the Seychelles Child Development Study","volume":"87","author":"Wallace","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib41","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1111\/j.1471-0528.2002.01307.x","article-title":"Relationship between total homocysteine and folate levels in pregnant women and their newborn babies according to maternal serum levels of vitamin B12","volume":"109","author":"Guerra-Shinohara","year":"2002","journal-title":"BJOG"},{"key":"10.1016\/j.nut.2010.10.017_bib42","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1515\/CCLM.2003.157","article-title":"Clinical B12 deficiency in one case of recurrent spontaneous pregnancy loss","volume":"41","author":"Candito","year":"2003","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.nut.2010.10.017_bib43","first-page":"69","article-title":"Maternal vitamin B12 and the risk of fetal neural tube defects in Egyptian patients","volume":"53","author":"Gaber","year":"2007","journal-title":"Clin Lab"},{"key":"10.1016\/j.nut.2010.10.017_bib44","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1097\/01.ede.0000257063.77411.e9","article-title":"Vitamin B12 and the risk of neural tube defects in a folic acid fortified population","volume":"18","author":"Ray","year":"2007","journal-title":"Epidemiology"},{"key":"10.1016\/j.nut.2010.10.017_bib45","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1515\/CCLM.2008.247","article-title":"Low serum vitamin B12 is associated with recurrent pregnancy loss in Syrian women","volume":"46","author":"H\u00fcbner","year":"2008","journal-title":"Clin Chem Lab Med"},{"key":"10.1016\/j.nut.2010.10.017_bib46","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s00125-007-0793-y","article-title":"Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study","volume":"51","author":"Yajnik","year":"2008","journal-title":"Diabetologia"},{"key":"10.1016\/j.nut.2010.10.017_bib47","doi-asserted-by":"crossref","first-page":"19995","DOI":"10.1073\/pnas.0709487104","article-title":"In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations","volume":"104","author":"Selhub","year":"2007","journal-title":"PNAS"},{"key":"10.1016\/j.nut.2010.10.017_bib48","first-page":"28","article-title":"Homociste\u00edna, folatos y vitamina B12 y c\u00e1ncer colorrectal. Estudio caso control en humanos","volume":"20","author":"Gonz\u00e1lez Gonz\u00e1lez","year":"2005","journal-title":"Nutr Hosp"},{"key":"10.1016\/j.nut.2010.10.017_bib49","first-page":"363","article-title":"Alonso-Aperte. Homociste\u00edna, vitaminas relacionadas y estilos de vida en personas de edad avanzada: estudio S\u00e9neca","volume":"22","author":"Varela-Moreiras","year":"2007","journal-title":"Nutr Hosp"},{"key":"10.1016\/j.nut.2010.10.017_bib50","series-title":"Deficiencia y suplementaci\u00f3n dietaria con \u00e1cido f\u00f3lico durante el crecimiento y el enevejecimiento en rata: estudio nutricional y bioqu\u00edmico. Diploma de estudios avanzados","author":"Partearroyo Cediel","year":"2006"},{"key":"10.1016\/j.nut.2010.10.017_bib51","first-page":"361","article-title":"Frequency of the mutation 677C-T of methylenetetrahydrofolate reductase gene on a sample of 652 Spanish liveborn infants","volume":"122","author":"Mart\u00ednez-Fr\u00edas","year":"2004","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.nut.2010.10.017_bib52","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1023\/A:1017978503416","article-title":"Prevalence of the methylenetetrahydrofolate reductase 677C>T mutation in the Mediterranean Spanish population. Association with cardiovascular risk factors","volume":"17","author":"Guill\u00e9n","year":"2001","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.nut.2010.10.017_bib53","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1157\/13045517","article-title":"Implicaci\u00f3n de los polimorfismos C677T y A1298C del gen MTHFR en el desarrollo de los defectos del tubo neural en la poblaci\u00f3n espa\u00f1ola","volume":"120","author":"Guti\u00e9rrez Revilla","year":"2003","journal-title":"Med Clin (Barc)"},{"key":"10.1016\/j.nut.2010.10.017_bib54","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1034\/j.1399-0004.2002.620309.x","article-title":"Lack of association between methylenetetrahydrofolate reductase (MTHFR) C677T and ischaemic heart disease (IHD): family-based association study in a Spanish population","volume":"62","author":"Gonz\u00e1lez-P\u00e9rez","year":"2002","journal-title":"Clin Genet"},{"key":"10.1016\/j.nut.2010.10.017_bib55","series-title":"Mutaci\u00f3n C677T en el gen de la metil\u00e9ntetrahidrofolato reductasa. Prevalencia y relaci\u00f3n con complicaciones de la gestaci\u00f3n. Diploma de estudios avanzados","author":"Gonz\u00e1lez Medina","year":"2001"},{"key":"10.1016\/j.nut.2010.10.017_bib56","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/S0029-7844(02)03120-4","article-title":"The 677 C-T methylenetetrahydrofolate reductase mutation does not predict increased maternal homocysteine during pregnancy","volume":"101","author":"Powers","year":"2003","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.nut.2010.10.017_bib57","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1373\/clinchem.2007.097469","article-title":"Effect of homocysteine concentration in early pregnancy on gestational hypertensive disorders and other pregnancy outcomes","volume":"54","author":"Dodds","year":"2008","journal-title":"Clin Chem"},{"key":"10.1016\/j.nut.2010.10.017_bib58","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1067\/mob.2000.109044","article-title":"Second-trimester plasma homocysteine levels and pregnancy-induced hypertension, preeclampsia, and intrauterine growth restriction","volume":"183","author":"Hogg","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.nut.2010.10.017_bib59","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1093\/ajcn\/76.6.1385","article-title":"Preconception homocysteine and B vitamin status and birth outcomes in Chineses women","volume":"76","author":"Ronnenberg","year":"2002","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2010.10.017_bib60","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1373\/49.9.1476","article-title":"Unexpected relationship between plasma homocysteine and intrauterine growth restriction","volume":"49","author":"Infante-Rivard","year":"2003","journal-title":"Clin Chem"},{"key":"10.1016\/j.nut.2010.10.017_bib61","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1159\/000090432","article-title":"Combining 2nd-trimester maternal serum homocysteine concentrations and uterine artery Doppler for prediction of preeclampsia and isolated intrauterine growth restriction","volume":"61","author":"Onalan","year":"2006","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.nut.2010.10.017_bib62","first-page":"719","article-title":"Serum folate and fetal growth retardation: a matter of compliance?","volume":"79","author":"Goldenberg","year":"1992","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.nut.2010.10.017_bib63","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0009-8981(01)00402-8","article-title":"Effect of smoking on serum concentrations of total homocysteine and B vitamins in mid-pregnancy","volume":"306","author":"Pag\u00e1n","year":"2001","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.nut.2010.10.017_bib64","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1053\/siny.2000.0025","article-title":"Perinatal complications associated with maternal tobacco use","volume":"5","author":"Andres","year":"2000","journal-title":"Semin Neonatol"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900710003588?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900710003588?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,8]],"date-time":"2019-06-08T23:52:18Z","timestamp":1560037938000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900710003588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":64,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S0899900710003588"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2010.10.017","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}