{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T16:56:06Z","timestamp":1695488166979},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2013,6,1]],"date-time":"2013-06-01T00:00:00Z","timestamp":1370044800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2013,6]]},"DOI":"10.1016\/j.nut.2012.12.026","type":"journal-article","created":{"date-parts":[[2013,2,21]],"date-time":"2013-02-21T14:59:44Z","timestamp":1361458784000},"page":"876-880","source":"Crossref","is-referenced-by-count":12,"title":["The effect of hyperhomocysteinemia on aortic distensibility in healthy individuals"],"prefix":"10.1016","volume":"29","author":[{"given":"Ioanna","family":"Eleftheriadou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pinelopi","family":"Grigoropoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ioannis","family":"Moyssakis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandros","family":"Kokkinos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Despoina","family":"Perrea","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Toutouzas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Katsilambros","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Tentolouris","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2012.12.026_bib1","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1055\/s-2005-872394","article-title":"Homocysteine: overview of biochemistry, molecular biology, and role in disease processes","volume":"5","author":"Fowler","year":"2005","journal-title":"Semin Vasc Med"},{"key":"10.1016\/j.nut.2012.12.026_bib2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s11883-006-0046-4","article-title":"Homocysteine: role and implications in atherosclerosis","volume":"8","author":"Guthikonda","year":"2006","journal-title":"Curr Atheroscler Rep"},{"key":"10.1016\/j.nut.2012.12.026_bib3","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1136\/bmj.325.7374.1202","article-title":"Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis","volume":"325","author":"Wald","year":"2002","journal-title":"Bmj"},{"key":"10.1016\/j.nut.2012.12.026_bib4","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1161\/01.HYP.34.4.837","article-title":"Plasma homocysteine, aortic stiffness, and renal function in hypertensive patients","volume":"34","author":"Bortolotto","year":"1999","journal-title":"Hypertension"},{"key":"10.1016\/j.nut.2012.12.026_bib5","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.ehj.2004.01.008","article-title":"Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study","volume":"25","author":"Sundstrom","year":"2004","journal-title":"Eur Heart J"},{"key":"10.1016\/j.nut.2012.12.026_bib6","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/sj.jhh.1001983","article-title":"Mild hyperhomocysteinaemia is associated with increased aortic stiffness in general population","volume":"20","author":"Mayer","year":"2006","journal-title":"J Hum Hypertens"},{"key":"10.1016\/j.nut.2012.12.026_bib7","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1161\/01.CIR.0000085067.55901.89","article-title":"Endothelial dysfunction induced by hyperhomocyst(e)inemia: role of asymmetric dimethylarginine","volume":"108","author":"Stuhlinger","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.nut.2012.12.026_bib8","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1093\/ajcn\/84.4.781","article-title":"Asymmetrical dimethylarginine regulates endothelial function in methionine-induced but not in chronic homocystinemia in humans: effect of oxidative stress and proinflammatory cytokines","volume":"84","author":"Antoniades","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2012.12.026_bib9","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1055\/s-0030-1248290","article-title":"Acute hyperhomocysteinemia impairs endothelium function in subjects with type 2 diabetes mellitus","volume":"118","author":"Doupis","year":"2010","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"10.1016\/j.nut.2012.12.026_bib10","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.1093\/eurheartj\/ehl254","article-title":"Expert consensus document on arterial stiffness: methodological issues and clinical applications","volume":"27","author":"Laurent","year":"2006","journal-title":"Eur Heart J"},{"key":"10.1016\/j.nut.2012.12.026_bib11","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1016\/S0140-6736(94)92577-1","article-title":"Aortic compliance measurements: a non-invasive indicator of atherosclerosis?","volume":"343","author":"Hopkins","year":"1994","journal-title":"Lancet"},{"key":"10.1016\/j.nut.2012.12.026_bib12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/j.1365-2362.2007.01906.x","article-title":"Impaired aortic elastic properties in patients with systemic sarcoidosis","volume":"38","author":"Moyssakis","year":"2008","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.nut.2012.12.026_bib13","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1093\/oxfordjournals.eurheartj.a059639","article-title":"Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease","volume":"11","author":"Stefanadis","year":"1990","journal-title":"Eur Heart J"},{"key":"10.1016\/j.nut.2012.12.026_bib14","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/S0894-7317(96)90476-9","article-title":"Doppler echocardiographic index for assessment of global right ventricular function","volume":"9","author":"Tei","year":"1996","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.nut.2012.12.026_bib15","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1111\/j.1365-2362.2003.01279.x","article-title":"Aortic distensibility is reduced in subjects with type 2 diabetes and cardiac autonomic neuropathy","volume":"33","author":"Tentolouris","year":"2003","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.nut.2012.12.026_bib16","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1161\/01.HYP.26.3.485","article-title":"Assessment of arterial distensibility by automatic pulse wave velocity measurement. Validation and clinical application studies","volume":"26","author":"Asmar","year":"1995","journal-title":"Hypertension"},{"key":"10.1016\/j.nut.2012.12.026_bib17","doi-asserted-by":"crossref","first-page":"2015","DOI":"10.1001\/jama.288.16.2015","article-title":"Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis","volume":"288","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.nut.2012.12.026_bib18","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1161\/01.ATV.18.4.535","article-title":"Influence of biochemical alterations on arterial stiffness in patients with end-stage renal disease","volume":"18","author":"Blacher","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.nut.2012.12.026_bib19","doi-asserted-by":"crossref","first-page":"411","DOI":"10.3109\/10641963.2010.549274","article-title":"Associations of plasma homocysteine levels with arterial stiffness in prehypertensive individuals","volume":"33","author":"Kim","year":"2011","journal-title":"Clin Exp Hypertens"},{"key":"10.1016\/j.nut.2012.12.026_bib20","first-page":"44","article-title":"Associations of plasma homocysteine and high-sensitivity C-reactive protein levels with arterial stiffness in Chinese population: a community-based study","volume":"125","author":"Feng","year":"2012","journal-title":"Chin Med J (Engl)"},{"key":"10.1016\/j.nut.2012.12.026_bib21","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1038\/sj.jhh.1002247","article-title":"Circulating homocysteine and large arterial stiffness and thickness in a population-based sample of middle-aged and elderly men","volume":"21","author":"Nakhai-Pour","year":"2007","journal-title":"J Hum Hypertens"},{"key":"10.1016\/j.nut.2012.12.026_bib22","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.ijcard.2005.11.045","article-title":"Homocysteine is not associated with arterial thickness and stiffness in healthy middle-aged French volunteers","volume":"113","author":"de Bree","year":"2006","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.nut.2012.12.026_bib23","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.numecd.2006.09.004","article-title":"Components of the metabolic syndrome, but not the metabolic syndrome per se, are associated with aortic distensibility","volume":"17","author":"Tentolouris","year":"2007","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1016\/j.nut.2012.12.026_bib24","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.atherosclerosis.2003.08.003","article-title":"Arterial stiffness is rapidly induced by raising the plasma homocysteine concentration with methionine","volume":"171","author":"Nestel","year":"2003","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.nut.2012.12.026_bib25","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1161\/01.ATV.18.12.1958","article-title":"Carotid and femoral artery wall thickness and stiffness in patients at risk for cardiovascular disease, with special emphasis on hyperhomocysteinemia","volume":"18","author":"Smilde","year":"1998","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.nut.2012.12.026_bib26","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1002\/clc.4960200505","article-title":"Coronary risk factors, endothelial function, and atherosclerosis: a review","volume":"20","author":"Vogel","year":"1997","journal-title":"Clin Cardiol"},{"key":"10.1016\/j.nut.2012.12.026_bib27","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1161\/01.CIR.98.18.1848","article-title":"Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults","volume":"98","author":"Bellamy","year":"1998","journal-title":"Circulation"},{"key":"10.1016\/j.nut.2012.12.026_bib28","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/S1096-7192(02)00030-6","article-title":"Upregulation of smooth muscle cell collagen production by homocysteine-insight into the pathogenesis of homocystinuria","volume":"76","author":"Majors","year":"2002","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.nut.2012.12.026_bib29","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2174\/157489009787259991","article-title":"Homocysteine and heart failure: an overview","volume":"4","author":"Vizzardi","year":"2009","journal-title":"Recent Pat Cardiovasc Drug Discov"},{"key":"10.1016\/j.nut.2012.12.026_bib30","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.atherosclerosis.2004.05.014","article-title":"Acute hyperhomocysteinemia decreases NO bioavailability in healthy adults","volume":"176","author":"Romerio","year":"2004","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.nut.2012.12.026_bib31","first-page":"135","article-title":"New non-invasive index for combined systolic and diastolic ventricular function","volume":"26","author":"Tei","year":"1995","journal-title":"J Cardiol"},{"key":"10.1016\/j.nut.2012.12.026_bib32","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0894-7317(97)70090-7","article-title":"Noninvasive Doppler-derived myocardial performance index: correlation with simultaneous measurements of cardiac catheterization measurements","volume":"10","author":"Tei","year":"1997","journal-title":"J Am Soc Echocardiogr"},{"key":"10.1016\/j.nut.2012.12.026_bib33","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.ahj.2004.07.022","article-title":"A Doppler-derived index of combined left ventricular systolic and diastolic function is an independent predictor of cardiovascular mortality in elderly men","volume":"149","author":"Arnlov","year":"2005","journal-title":"Am Heart J"},{"key":"10.1016\/j.nut.2012.12.026_bib34","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1161\/CIRCULATIONAHA.106.633750","article-title":"Elevated homocysteine is associated with reduced regional left ventricular function: the Multi-Ethnic Study of Atherosclerosis","volume":"115","author":"Nasir","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.nut.2012.12.026_bib35","doi-asserted-by":"crossref","first-page":"H812","DOI":"10.1152\/ajpheart.01042.2003","article-title":"Acute negative inotropic effects of homocysteine are mediated via the endothelium","volume":"287","author":"Kennedy","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.nut.2012.12.026_bib36","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0735-1097(02)02069-7","article-title":"Homocysteine impairs coronary microvascular dilator function in humans","volume":"40","author":"Tawakol","year":"2002","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.nut.2012.12.026_bib37","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/0002-9343(92)90577-X","article-title":"Ascending aorta distensibility abnormalities in hypertensive patients and response to nifedipine administration","volume":"93","author":"Stratos","year":"1992","journal-title":"Am J Med"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900713000154?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900713000154?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,9]],"date-time":"2019-07-09T20:34:28Z","timestamp":1562704468000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900713000154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2013,6]]}},"alternative-id":["S0899900713000154"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2012.12.026","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}