{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:11:05Z","timestamp":1791000665898,"version":"4.1.0"},"reference-count":76,"publisher":"Elsevier BV","issue":"11-12","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2013,11]]},"DOI":"10.1016\/j.nut.2013.03.024","type":"journal-article","created":{"date-parts":[[2013,7,9]],"date-time":"2013-07-09T01:01:44Z","timestamp":1373331704000},"page":"1293-1299","source":"Crossref","is-referenced-by-count":224,"title":["Non-nutritive sweeteners: Review and update"],"prefix":"10.1016","volume":"29","author":[{"given":"Padmini","family":"Shankar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suman","family":"Ahuja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishnan","family":"Sriram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2013.03.024_bib1","doi-asserted-by":"crossref","first-page":"4117","DOI":"10.2174\/138161209789909674","article-title":"Fatty acids and obesity","volume":"15","author":"Mendendez de la Granda","year":"2009","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.nut.2013.03.024_bib2","doi-asserted-by":"crossref","first-page":"236","DOI":"10.4103\/0976-500X.85936","article-title":"Sugar substitutes: health controversy over perceived benefits","volume":"2","author":"Tandel","year":"2011","journal-title":"J Pharmacol Pharmacother"},{"key":"10.1016\/j.nut.2013.03.024_bib3","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1007\/s00216-011-4937-z","article-title":"Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection","volume":"400","author":"Zygler","year":"2011","journal-title":"Anal Bioanal Chem"},{"issue":"3","key":"10.1016\/j.nut.2013.03.024_bib4","doi-asserted-by":"crossref","first-page":"640","DOI":"10.3945\/ajcn.112.034751","article-title":"Low-calorie sweetener consumption is increasing in the United States","volume":"96","author":"Sylvetsky","year":"2012","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib5","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1093\/annonc\/mdh256","article-title":"Artificial sweeteners\u2013do they bear a carcinogenic risk?","volume":"15","author":"Weihrauch","year":"2004","journal-title":"Ann Oncol"},{"key":"10.1016\/j.nut.2013.03.024_bib6","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1016\/j.jand.2012.03.009","article-title":"Use of nutritive and nonnutritive sweeteners","volume":"112","year":"2012","journal-title":"J Acad Nutr Diet"},{"key":"10.1016\/j.nut.2013.03.024_bib7","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1016\/j.jada.2003.09.021","article-title":"Lack of effect of sucralose on glucose homeostasis in subjects with type 2 diabetes","volume":"103","author":"Grotz","year":"2003","journal-title":"J Am Diet Assn"},{"key":"10.1016\/j.nut.2013.03.024_bib8","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1093\/jn\/126.6.1601","article-title":"D-tagatose is a bulk sweetener with zero energy determined in rats","volume":"126","author":"Livesey","year":"1996","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib9","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.appet.2010.08.021","article-title":"Body weight gain in rats consuming sweetened liquids: effects of caffeine and diet composition","volume":"55","author":"Swithers","year":"2010","journal-title":"Appetite"},{"key":"10.1016\/j.nut.2013.03.024_bib10","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1001\/archpedi.157.9.882","article-title":"Television watching and soft drink consumption: association with obesity in 11- to 13-year old school children","volume":"157","author":"Giammattei","year":"2003","journal-title":"Arch Pediatr Adolesc Med"},{"key":"10.1016\/j.nut.2013.03.024_bib11","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1080\/09637480120092143","article-title":"Total beverage consumption and beverage choices among children and adolescents","volume":"54","author":"Forshee","year":"2003","journal-title":"Int J Food Sci Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1080\/07315724.2005.10719449","article-title":"Beverage consumption patterns in elementary school aged children across a two-year period","volume":"24","author":"Blum","year":"2005","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib13","doi-asserted-by":"crossref","first-page":"S1155","DOI":"10.3945\/jn.111.149609","article-title":"The use of low-calorie sweeteners by children: Implications for weight management","volume":"142","author":"Foreyt","year":"2012","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib14","doi-asserted-by":"crossref","first-page":"S1163","DOI":"10.3945\/jn.111.149617","article-title":"The use of low-calorie sweeteners by adults: Impact on weight management","volume":"142","author":"Anderson","year":"2012","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib15","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1007\/s13668-012-0029-8","article-title":"Gene-diet interactions in complex diseases: current findings and relevance for public health","volume":"1","author":"Qi","year":"2012","journal-title":"Curr Nutr Rep"},{"key":"10.1016\/j.nut.2013.03.024_bib16","first-page":"407","article-title":"Sugar content in artificial sweetener","volume":"2","author":"Mukherjee","year":"2011","journal-title":"Adv Appl Sci Res"},{"key":"10.1016\/j.nut.2013.03.024_bib17","first-page":"213","article-title":"Editor. Saccharin deemed \u201cnot hazardous\u201d in United States and abroad","volume":"18","year":"2010","journal-title":"Curr Oncol"},{"key":"10.1016\/j.nut.2013.03.024_bib18","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/19440049.2011.627572","article-title":"Dietary intake of artificial sweeteners by the Belgian population","volume":"29","author":"Huvaere","year":"2012","journal-title":"Food Addit Contam Part A Chem Anal Control Expo Risk Assess"},{"key":"10.1016\/j.nut.2013.03.024_bib19","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1080\/02652030600944395","article-title":"Usage of saccharin in food products and its intake by the population of Lucknow, India","volume":"23","author":"Tripathi","year":"2006","journal-title":"Food Addit Contam"},{"key":"10.1016\/j.nut.2013.03.024_bib20","unstructured":"Artificial sweeteners and cancer. National Cancer Institute. Available at m.cancer.gov\/topics\/factsheets\/artificial-sweeteners. Accessed February 19, 2013."},{"key":"10.1016\/j.nut.2013.03.024_bib21","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/annonc\/mdl346","article-title":"Artificial sweeteners and cancer risk in a network of case\u2013control studies","volume":"18","author":"Gallus","year":"2007","journal-title":"Ann Oncol"},{"key":"10.1016\/j.nut.2013.03.024_bib22","first-page":"327","article-title":"News and views\u2014No longer too sweet to be wholesome","volume":"2","year":"2000","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.nut.2013.03.024_bib23","doi-asserted-by":"crossref","first-page":"2235","DOI":"10.1158\/1055-9965.EPI-09-0365","article-title":"Artificial sweeteners and the risk of gastric, pancreatic, and endometrial cancers in Italy","volume":"18","author":"Bosetti","year":"2009","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.nut.2013.03.024_bib24","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.physbeh.2009.12.021","article-title":"High intensity sweeteners and energy balance","volume":"100","author":"Swithers","year":"2012","journal-title":"Physiol Behav"},{"key":"10.1016\/j.nut.2013.03.024_bib25","unstructured":"U.S. Department of Health and Human Services. Food guidance for industry: frequently asked questions about GRAS. U.S. Department of Health and\u00a0Human Services. Food and Drug Administration. Center for Food Safety\u00a0and\u00a0Applied Nutrition. Available at http:\/\/www.fda.gov\/Food\/GuidanceComplianceRegulatoryInformation\/GuidanceDocuments. Accessed February 19,\u00a02013."},{"key":"10.1016\/j.nut.2013.03.024_bib26","unstructured":"FDA statement on European aspartame study. CFSAN\/Office of Food Additive Safety. Available at www.fda.gov\/Food\/FoodingredientsPackaging\/FoodAdditives\/ucm208580. Accessed February 19,\u00a02013."},{"key":"10.1016\/j.nut.2013.03.024_bib27","unstructured":"Learn about cancer. Aspartame. Available at http:\/\/www.cancer.org\/Cancer\/CancerCauses\/OtherCarcinogens\/AtHome\/aspartame. Accessed October 4,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib28","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.appet.2010.03.009","article-title":"Effects of stevia, aspartame, and sucrose on food intake, satiety, and postprandial glucose and insulin levels","volume":"55","author":"Anton","year":"2010","journal-title":"Appetite"},{"key":"10.1016\/j.nut.2013.03.024_bib29","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1093\/ajcn\/82.5.1011","article-title":"Functional magnetic resonance imaging of human hypothalamic responses to sweet taste and calories 1\u20192\u20193","volume":"82","author":"Smeets","year":"2005","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib30","doi-asserted-by":"crossref","first-page":"251","DOI":"10.3928\/08910162-20080601-02","article-title":"The potential toxicity of artificial sweeteners","volume":"56","author":"Whitehouse","year":"2008","journal-title":"AAOHN J"},{"key":"10.1016\/j.nut.2013.03.024_bib31","unstructured":"Walton RG. Survey of aspartame studies: correlation of outcome and funding sources. Available at www.dorway.com\/peerrev.html. Accessed October 4,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib32","first-page":"1787","article-title":"Aspartame ingestion and headaches","volume":"44","author":"Van Den Eeden","year":"1994","journal-title":"AAA"},{"key":"10.1016\/j.nut.2013.03.024_bib33","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1111\/j.1526-4610.1989.hed2902090.x","article-title":"Aspartame as a dietary trigger of headache","volume":"29","author":"Lipton","year":"1989","journal-title":"Headache"},{"key":"10.1016\/j.nut.2013.03.024_bib34","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1046\/j.1526-4610.2001.041009899.x","article-title":"Migraine MLT-down: an unusual presentation of migraine in patients with aspartame-triggered headaches","volume":"41","author":"Newman","year":"2001","journal-title":"Headache"},{"key":"10.1016\/j.nut.2013.03.024_bib35","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1289\/ehp.877553","article-title":"Possible neurologic effects of aspartame, a widely used food additive","volume":"75","author":"Maher","year":"1987","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.nut.2013.03.024_bib36","doi-asserted-by":"crossref","first-page":"689","DOI":"10.4067\/S0717-95022007000400004","article-title":"Effects of aspartame on fetal kidney: a morphometric and stereological study","volume":"25","author":"Martins","year":"2007","journal-title":"Int J Morphol"},{"key":"10.1016\/j.nut.2013.03.024_bib37","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1093\/jnci\/89.14.1072","article-title":"Aspartame consumption in relation to childhood brain tumor risk: results from a case\u2013control study","volume":"89","author":"Gurney","year":"1997","journal-title":"J Natl Cancer Inst"},{"key":"10.1016\/j.nut.2013.03.024_bib38","unstructured":"Acesulfame K. Calorie Control Council. 2012. Available at www.caloriecontrol.org\/sweeteners-and-lite\/sugar-substitutes\/acesulfame-K. Accessed October 2,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib39","unstructured":"Sweet facts about acesulfame potassium. Calorie Control Council. 2010. Available at www.acesulfamek.org\/faq.html#. Accessed October 2,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib40","unstructured":"Chemical Cuisine \u2013 Learn about food additives. Center for Science in the\u00a0Public Interest. 2012. Available at http:\/\/www.cspinet.org\/reports\/chemcuisine.htm. Accessed October 4,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib41","unstructured":"The lowdown on low-calorie sweeteners. The Coca-Cola Company."},{"key":"10.1016\/j.nut.2013.03.024_bib42","unstructured":"IFIC Review: Low-Calorie Sweeteners and Health. Food Insight \u2013 Your nutrition and food safety resource. 2009. Available at http:\/\/www.foodinsight.org\/Resources\/Detail.aspx?topic=IFIC_Review_Low_Calorie_Sweeteners_and_Health. Accessed October 2,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib43","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1080\/02652030802195309","article-title":"Estimated intake of the sweeteners, acesulfame-K and aspartame, from soft drinks, soft drinks based on mineral waters and nectars for a group of Portuguese teenage students","volume":"25","author":"Lino","year":"2008","journal-title":"Food Addit Contam"},{"key":"10.1016\/j.nut.2013.03.024_bib44","unstructured":"Facts about low-calorie sweeteners. International Food Information Council Foundation. 2009. Available at www.foodinsight.org. Accessed October 2,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib45","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0278-6915(99)00115-5","article-title":"In\u00a0vivo cytogenetic studies on blends of aspartame and acesulfame-K","volume":"38","author":"Mukhopadhyay","year":"2000","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.nut.2013.03.024_bib46","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1541-4337.2006.tb00081.x","article-title":"Low-calorie sweeteners and other sugar substitutes: A review of the safety issues","volume":"5","author":"Kroger","year":"2006","journal-title":"Compr Rev Food Sci Food Saf"},{"key":"10.1016\/j.nut.2013.03.024_bib47","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1136\/bmj.313.7054.386","article-title":"US scientists challenge approval of sweetener","volume":"313","author":"Woods","year":"1996","journal-title":"BMJ"},{"key":"10.1016\/j.nut.2013.03.024_bib48","unstructured":"Sucralose. Calorie Control Council. 2012. Available at http:\/\/www.caloriecontrol.org\/sweeteners-and-lite\/sugar-substitutes\/sucralose. Accessed October 3,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib49","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1139\/y94-063","article-title":"The development and applications of sucralose, a new high-intensity sweetener","volume":"72","author":"Knight","year":"1994","journal-title":"Can J Physiol Pharmacol"},{"key":"10.1016\/j.nut.2013.03.024_bib50","unstructured":"International Food Information Council Foundation. 2010. Everything you need to know about sucralose. Washington DC. IFIC. Available at http:\/\/www.foodinsight.org\/Resources\/Detail.aspx?topic=Everything_You_Need_to_Know_About_Sucralose. Accessed October 4,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib51","unstructured":"All about Sucralose. Calorie Control Council. 2012. Available at http:\/\/www.sucralose.org\/. Accessed October 2,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib52","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1111\/j.1745-459X.2008.00187.x","article-title":"Descriptive profile of peach nectar sweetened with sucrose and different sweeteners","volume":"23","author":"Cardoso","year":"2008","journal-title":"J Sens Stud"},{"key":"10.1016\/j.nut.2013.03.024_bib53","first-page":"15559","article-title":"Food labeling: health claims;dietary non cariogenic carbohydrate sweeteners and dental caries. Final rule","volume":"71","author":"Food and Drug Administration","year":"2006","journal-title":"Fed Regist"},{"key":"10.1016\/j.nut.2013.03.024_bib54","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.1016\/j.fct.2010.07.047","article-title":"The absence of genotoxicity of sucralose","volume":"48","author":"Brusick","year":"2010","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.nut.2013.03.024_bib55","doi-asserted-by":"crossref","first-page":"1415","DOI":"10.1080\/15287390802328630","article-title":"Splenda alters gut microflora and increases intestinal P-glycoprotein and cytochrome P-450 in male rats","volume":"71","author":"Abou-Donia","year":"2008","journal-title":"J Toxicol Environ Health"},{"key":"10.1016\/j.nut.2013.03.024_bib56","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.yrtph.2009.06.013","article-title":"Expert panel report on a study of Splenda in male rats","volume":"55","author":"Brusick","year":"2009","journal-title":"Regul Toxicol Pharm"},{"key":"10.1016\/j.nut.2013.03.024_bib57","unstructured":"Calorie Control Council. Sucralose\u2014The Facts 2009. Available at www.caloriecontrol.org. Accessed October 3,\u00a02012."},{"key":"10.1016\/j.nut.2013.03.024_bib58","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1017\/S0007114510001327","article-title":"Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects","volume":"104","author":"Ma","year":"2010","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib59","doi-asserted-by":"crossref","first-page":"G735","DOI":"10.1152\/ajpgi.90708.2008","article-title":"Effect of the artificial sweetener, sucralose, on gastric emptying and incretin hormone release in healthy subjects","volume":"296","author":"Ma","year":"2009","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.nut.2013.03.024_bib60","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/ejcn.2010.291","article-title":"Effects of oral ingestion of sucralose on gut hormone response and appetite in healthy normal-weight subjects","volume":"65","author":"Ford","year":"2011","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib61","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1016\/j.nutres.2011.10.004","article-title":"Short-term consumption of sucralose, a non-nutritive sweetener, is similar to water with regard to select markers of hunger signaling and short-term glucose homeostasis in women","volume":"31","author":"Brown","year":"2011","journal-title":"Nutr Res"},{"key":"10.1016\/j.nut.2013.03.024_bib62","doi-asserted-by":"crossref","first-page":"S43","DOI":"10.1016\/S0278-6915(00)00027-2","article-title":"Sucralose: Assessment of teratogenic potential in the rat and the rabbit","volume":"38","author":"Killie","year":"2000","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.nut.2013.03.024_bib63","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1526-4610.2006.00386_1.x","article-title":"Migraine triggered by sucralose: A case report","volume":"46","author":"Bigal","year":"2006","journal-title":"Headache"},{"key":"10.1016\/j.nut.2013.03.024_bib64","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1111\/j.1526-4610.2006.00543_1.x","article-title":"Popular sweetener sucralose as a migraine trigger","volume":"46","author":"Patel","year":"2006","journal-title":"Headache"},{"key":"10.1016\/j.nut.2013.03.024_bib65","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1155\/2011\/451036","article-title":"What made Canada become a country with the highest incidence of\u00a0inflammatory bowel disease: Could sucralose be the culprit?","volume":"25","author":"Qin","year":"2011","journal-title":"Can J Gastroenterol"},{"key":"10.1016\/j.nut.2013.03.024_bib66","doi-asserted-by":"crossref","first-page":"R16","DOI":"10.1111\/j.1750-3841.2008.01005.x","article-title":"Technological and functional applications of low- calorie sweeteners from lactic acid bacteria","volume":"74","author":"Patra","year":"2009","journal-title":"J Food Sci"},{"key":"10.1016\/j.nut.2013.03.024_bib67","doi-asserted-by":"crossref","first-page":"S1161","DOI":"10.1093\/ajcn\/62.5.1161S","article-title":"Sugar substitutes: their energy values, bulk characteristics, and potential health benefits","volume":"62","author":"Levin","year":"1995","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib68","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1038\/scientificamerican0587-90","article-title":"Glucose and aging","volume":"256","author":"Cerami","year":"1987","journal-title":"Sci Am"},{"key":"10.1016\/j.nut.2013.03.024_bib69","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1463-1326.2007.00799.x","article-title":"Tagatose, a new antidiabetic and obesity control drug","volume":"10","author":"Lu","year":"2008","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.nut.2013.03.024_bib70","doi-asserted-by":"crossref","first-page":"S1169","DOI":"10.1093\/ajcn\/62.5.1169S","article-title":"Methods available to estimate the energy values of sugar alcohols","volume":"62","author":"Ellwood","year":"1995","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib71","unstructured":"EC. European Parliament and Council Directive No. 95\/2\/EC of February 1995 on food additives other than colours and sweeteners. Off. J. Eur. Communities L061."},{"key":"10.1016\/j.nut.2013.03.024_bib72","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1093\/ajcn\/65.4.947","article-title":"Metabolic response to lactitol and xylitol in healthy men","volume":"65","author":"Natah","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nut.2013.03.024_bib73","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/chemse\/bjq033","article-title":"Stevia and saccharin preferences in rats and mice","volume":"35","author":"Sclafani","year":"2010","journal-title":"Chem Senses"},{"key":"10.1016\/j.nut.2013.03.024_bib74","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1046\/j.1365-2125.2000.00260.x","article-title":"A double-blind placebo-controlled study of the effectiveness and tolerability of oral stevioside in human hypertension","volume":"50","author":"Chan","year":"2000","journal-title":"Br J Clin Pharmacol"},{"key":"10.1016\/j.nut.2013.03.024_bib75","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1161\/CIR.0b013e31825c42ee","article-title":"Non-nutritive sweeteners: current use and health perspectives: A scientific statement from the American Heart Association and the American Diabetes Association","volume":"126","author":"Gardner","year":"2012","journal-title":"Circulation"},{"key":"10.1016\/j.nut.2013.03.024_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2012.03.008","article-title":"Is obesity development associated with dietary sugar intake in the U.S.?","author":"Song","year":"2012","journal-title":"Nutrition"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900713002190?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900713002190?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T03:34:56Z","timestamp":1715657696000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900713002190"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,11]]},"references-count":76,"journal-issue":{"issue":"11-12","published-print":{"date-parts":[[2013,11]]}},"alternative-id":["S0899900713002190"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2013.03.024","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2013,11]]}}}