{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T14:06:31Z","timestamp":1788962791726,"version":"build-2803163510"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010031","name":"Postdoctoral Research Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010031","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.nut.2020.110940","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T11:59:47Z","timestamp":1593777587000},"page":"110940","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Pterostilbene attenuates liver injury and oxidative stress in intrauterine growth\u2013retarded weanling piglets"],"prefix":"10.1016","volume":"81","author":[{"given":"Hao","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueping","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuli","family":"Ji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peilu","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxiong","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2020.110940_bib0001","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.placenta.2016.11.012","article-title":"Neuroinflammation in intrauterine growth restriction","volume":"54","author":"Wixey","year":"2017","journal-title":"Placenta"},{"key":"10.1016\/j.nut.2020.110940_bib0002","doi-asserted-by":"crossref","first-page":"1270","DOI":"10.1038\/ijo.2012.54","article-title":"Effect of intrauterine growth retardation on liver and long-term metabolic risk","volume":"36","author":"Cianfarani","year":"2012","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.nut.2020.110940_bib0003","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1177\/1933719112440052","article-title":"Protective effect of N-acetylcysteine on liver damage during chronic intrauterine hypoxia in fetal guinea pig","volume":"19","author":"Hashimoto","year":"2012","journal-title":"Reprod Sci"},{"key":"10.1016\/j.nut.2020.110940_bib0004","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1093\/jn\/138.1.60","article-title":"Intrauterine growth restriction affects the proteomes of the small intestine, liver, and skeletal muscle in newborn pigs","volume":"138","author":"Wang","year":"2008","journal-title":"J Nutr"},{"key":"10.1016\/j.nut.2020.110940_bib0005","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1159\/000106488","article-title":"Role of oxidative stress in intrauterine growth restriction","volume":"64","author":"Biri","year":"2007","journal-title":"Gynecol Obstet Invest"},{"key":"10.1016\/j.nut.2020.110940_bib0006","doi-asserted-by":"crossref","first-page":"e27626","DOI":"10.1371\/journal.pone.0027626","article-title":"Cord blood glutathione depletion in preterm infants: correlation with maternal cysteine depletion","volume":"6","author":"K\u00fcster","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/j.nut.2020.110940_bib0007","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/582748","article-title":"Impact of oxidative stress in fetal programming","author":"Thompson","year":"2012","journal-title":"J Pregnancy"},{"key":"10.1016\/j.nut.2020.110940_bib0008","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1177\/0394632015621319","article-title":"Blueberry treatment attenuated cirrhotic and preneoplastic lesions and oxidative stress in the liver of diethylnitrosamine-treated rats","volume":"29","author":"Bing\u00fcl","year":"2016","journal-title":"Int J Immunopathol. Pharmacol"},{"key":"10.1016\/j.nut.2020.110940_bib0009","doi-asserted-by":"crossref","first-page":"3180","DOI":"10.1021\/jf803579e","article-title":"Dietary administration of high doses of pterostilbene and quercetin to mice is not toxic","volume":"57","author":"Ruiz","year":"2009","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.nut.2020.110940_bib0010","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/463595","article-title":"Analysis of safety from a human clinical trial with pterostilbene","author":"Riche","year":"2013","journal-title":"J Toxicol"},{"key":"10.1016\/j.nut.2020.110940_bib0011","doi-asserted-by":"crossref","first-page":"1308","DOI":"10.1002\/bmc.1254","article-title":"Determination of pterostilbene in rat plasma by a simple HPLC-UV method and its application in pre-clinical pharmacokinetic study","volume":"23","author":"Lin","year":"2009","journal-title":"Biomed Chromatogr"},{"key":"10.1016\/j.nut.2020.110940_bib0012","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.ejphar.2016.07.046","article-title":"Promising therapeutic potential of pterostilbene and its mechanistic insight based on preclinical evidence","volume":"789","author":"Kosuru","year":"2016","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.nut.2020.110940_bib0013","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1039\/c1mb05023k","article-title":"A metabolic system-wide characterisation of the pig: a model for human physiology","volume":"7","author":"Merrifield","year":"2011","journal-title":"Mol Biosyst"},{"key":"10.1016\/j.nut.2020.110940_bib0014","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201600653","article-title":"Resveratrol attenuates mitochondrial dysfunction in the liver of intrauterine growth retarded suckling piglets by improving mitochondrial biogenesis and redox status","volume":"61","author":"Zhang","year":"2017","journal-title":"Mol Nutr Food Res"},{"key":"10.1016\/j.nut.2020.110940_bib0015","series-title":"Nutrient requirements of swine","year":"2012"},{"key":"10.1016\/j.nut.2020.110940_bib0016","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0143220","article-title":"Quantitative shear-wave elastography of the liver in preterm neonates with intra-uterine growth restriction","volume":"10","author":"Alison","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.nut.2020.110940_bib0017","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1677\/joe.1.06269","article-title":"Oxidative and nitrosative stress in brain mitochondria of diabetic rats","volume":"187","author":"Mastrocola","year":"2005","journal-title":"J Endocrinol"},{"key":"10.1016\/j.nut.2020.110940_bib0018","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1186\/1472-6882-13-238","article-title":"Protective effect of pterostilbene against free radical mediated oxidative damage","volume":"13","author":"Acharya","year":"2013","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/j.nut.2020.110940_bib0019","doi-asserted-by":"crossref","first-page":"22586","DOI":"10.1074\/jbc.M101846200","article-title":"Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol","volume":"276","author":"Stivala","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.nut.2020.110940_bib0020","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.bioorg.2006.04.001","article-title":"Structure-activity relationship studies of resveratrol and its analogues by the reaction kinetics of low density lipoprotein peroxidation","volume":"34","author":"Cheng","year":"2006","journal-title":"Bioorg Chem"},{"key":"10.1016\/j.nut.2020.110940_bib0021","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1242\/jeb.201.8.1203","article-title":"Oxygen toxicity: a radical explanation","volume":"201","author":"Fridovich","year":"1998","journal-title":"J Exp Biol"},{"key":"10.1016\/j.nut.2020.110940_bib0022","doi-asserted-by":"crossref","first-page":"22559","DOI":"10.1074\/jbc.M101053200","article-title":"In vivo role of NAD (P) H: quinoneoxidoreductase 1 (NQO1) in the regulation of intracellular redox state and accumulation of abdominal adipose tissue","volume":"276","author":"Gaikwad","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.nut.2020.110940_bib0023","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/j.bbrc.2007.03.045","article-title":"Gpx4 protects mitochondrial ATP generation against oxidative damage","volume":"356","author":"Liang","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.nut.2020.110940_bib0024","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.fct.2014.07.038","article-title":"The berry constituents quercetin, kaempferol, and pterostilbene synergistically attenuate reactive oxygen species: involvement of the Nrf2-ARE signaling pathway","volume":"72","author":"Saw","year":"2014","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.nut.2020.110940_bib0025","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/jbt.21604","article-title":"Protective effects of pterostilbene against acetaminophen-induced hepatotoxicity in rats","volume":"29","author":"El-Sayed","year":"2015","journal-title":"J Biochem Mol Toxicol"},{"key":"10.1016\/j.nut.2020.110940_bib0026","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1021\/acs.chemrestox.5b00378","article-title":"Pterostilbene ameliorates streptozotocin-induced diabetes through enhancing antioxidant signaling pathways mediated by Nrf2","volume":"29","author":"Elango","year":"2016","journal-title":"Chem Res Toxicol"},{"key":"10.1016\/j.nut.2020.110940_bib0027","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.tox.2006.06.008","article-title":"Glutathione peroxidase and glutathione reductase activities are partially responsible for determining the susceptibility of cells to oxidative stress","volume":"226","author":"Yang","year":"2006","journal-title":"Toxicology"},{"key":"10.1016\/j.nut.2020.110940_bib0028","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1002\/biof.179","article-title":"Schisandrin B enhances the glutathione redox cycling and protects against oxidant injury in different types of cultured cells","volume":"37","author":"Lam","year":"2011","journal-title":"BioFactors"},{"key":"10.1016\/j.nut.2020.110940_bib0029","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.molmed.2004.09.003","article-title":"Nrf2-Keap1 defines a physiologically important stress response mechanism","volume":"10","author":"Motohashi","year":"2004","journal-title":"Trends Mol Med"},{"key":"10.1016\/j.nut.2020.110940_bib0030","doi-asserted-by":"crossref","first-page":"3378","DOI":"10.1016\/j.bmc.2016.05.011","article-title":"Pterostilbene-mediated Nrf2 activation: mechanistic insights on Keap1: Nrf2 interface","volume":"24","author":"Bhakkiyalakshmi","year":"2016","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.nut.2020.110940_bib0031","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3389\/fphar.2019.00497","article-title":"Pterostilbene activates the Nrf2-dependent antioxidant response to ameliorate arsenic-induced intracellular damage and apoptosis in human keratinocytes","volume":"10","author":"Zhou","year":"2019","journal-title":"Front Pharmacol"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900720302239?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900720302239?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T12:12:23Z","timestamp":1760271143000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900720302239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":31,"alternative-id":["S0899900720302239"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2020.110940","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pterostilbene attenuates liver injury and oxidative stress in intrauterine growth\u2013retarded weanling piglets","name":"articletitle","label":"Article Title"},{"value":"Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nut.2020.110940","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"110940"}}