{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T02:21:32Z","timestamp":1787797292033,"version":"build-2784847793"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1016\/j.nut.2020.111024","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T23:24:43Z","timestamp":1600385083000},"page":"111024","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Effectiveness of oral vitamin D supplementation in lessening disease severity among patients with psoriasis: A systematic review and meta-analysis of randomized controlled trials"],"prefix":"10.1016","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9810-7583","authenticated-orcid":false,"given":"Xenophon","family":"Theodoridis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4167-6595","authenticated-orcid":false,"given":"Maria G.","family":"Grammatikopoulou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni-Maria","family":"Stamouli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Persefoni","family":"Talimtzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eirini","family":"Pagkalidou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6594-7292","authenticated-orcid":false,"given":"Efterpi","family":"Zafiriou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna-Bettina","family":"Haidich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dimitrios P.","family":"Bogdanos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2020.111024_bib0001","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/jdv.13854","article-title":"A systematic review of worldwide epidemiology of psoriasis","volume":"31","author":"Michalek","year":"2017","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.nut.2020.111024_bib0002","doi-asserted-by":"crossref","first-page":"60","DOI":"10.5114\/pdia.2016.62287","article-title":"Associations between site of skin lesions and depression, social anxiety, body-related emotions and feelings of stigmatization in psoriasis patients","volume":"35","author":"\u0141akuta","year":"2018","journal-title":"Postep Dermatologii i Alergol"},{"key":"10.1016\/j.nut.2020.111024_bib0003","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/bjd.18899","article-title":"Facets of shame are differently expressed in dermatological disease: a prospective observational study","volume":"183","author":"Aberer","year":"2020","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0004","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1001\/archderm.138.3.337","article-title":"Association of dissatisfaction with care and psychiatric morbidity with poor treatment compliance","volume":"138","author":"Renzi","year":"2002","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0005","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1080\/03007995.2019.1618805","article-title":"Psoriasis treatment patterns: a retrospective claims study","volume":"35","author":"Higa","year":"2019","journal-title":"Curr Med Res Opin"},{"key":"10.1016\/j.nut.2020.111024_bib0006","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s00403-018-1808-x","article-title":"Treatment preferences and treatment satisfaction among psoriasis patients: a systematic review","volume":"310","author":"Florek","year":"2018","journal-title":"Arch Dermatol Res"},{"key":"10.1016\/j.nut.2020.111024_bib0007","doi-asserted-by":"crossref","first-page":"872","DOI":"10.3389\/fphar.2019.00872","article-title":"Mini review: new treatments in psoriatic arthritis. focus on the IL-23\/17 axis","volume":"10","author":"Sakkas","year":"2019","journal-title":"Front Pharmacol"},{"key":"10.1016\/j.nut.2020.111024_bib0008","doi-asserted-by":"crossref","first-page":"2240","DOI":"10.1093\/rheumatology\/kez204","article-title":"Apremilast increases IL-10-producing regulatory B cells and decreases proinflammatory T cells and innate cells in psoriatic arthritis and psoriasis","volume":"58","author":"Mavropoulos","year":"2019","journal-title":"Rheumatology"},{"key":"10.1016\/j.nut.2020.111024_bib0009","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/1346-8138.13512","article-title":"Biosimilars in psoriasis: Clinical practice and regulatory perspectives in Latin America","volume":"44","author":"de la Cruz","year":"2017","journal-title":"J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0010","doi-asserted-by":"crossref","DOI":"10.1111\/1346-8138.15196","article-title":"Japanese guidance for use of biologics for psoriasis (the 2019 version)","author":"Saeki","year":"2020","journal-title":"J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0011","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1111\/bjd.18876","article-title":"A changed life: the life experiences of patients with psoriasis receiving biological treatment","volume":"183","author":"Trettin","year":"2020","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0012","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1111\/bjd.18662","article-title":"How many people develop anti-drug antibodies to the biologic drug tildrakizumab, and what impact does this have on the effectiveness of their treatment","volume":"182","author":"Kimball","year":"2020","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0013","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1111\/bjd.18851","article-title":"A head\u2010to\u2010head comparison of ixekizumab vs. guselkumab in patients with moderate\u2010to\u2010severe plaque psoriasis: 12\u2010week efficacy, safety and speed of response from a randomized, double\u2010blinded trial","volume":"182","author":"Blauvelt","year":"2020","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0014","doi-asserted-by":"crossref","unstructured":"Megna M, Fabbrocini G, Camela E, Cinelli E. Apremilast efficacy and safety in elderly psoriasis patients over a 48-week Period. J Eur Acad Dermatology Venereol https:\/\/doi.org\/10.1111\/jdv.16443","DOI":"10.1111\/jdv.16443"},{"key":"10.1016\/j.nut.2020.111024_bib0015","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s11154-017-9411-6","article-title":"Vitamin D and its role in psoriasis: an overview of the dermatologist and nutritionist","volume":"18","author":"Barrea","year":"2017","journal-title":"Rev Endocr Metab Disord"},{"key":"10.1016\/j.nut.2020.111024_bib0016","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1016\/j.jaad.2013.06.027","article-title":"Topical treatments for chronic plaque psoriasis: an abridged Cochrane Systematic Review","volume":"69","author":"Mason","year":"2013","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0017","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1111\/ced.13381","article-title":"Association between circulating 25-hydroxyvitamin D levels and psoriasis, and correlation with disease severity: a meta-analysis","volume":"43","author":"Lee","year":"2018","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0018","doi-asserted-by":"crossref","first-page":"103","DOI":"10.17161\/kjm.v12i4.13255","article-title":"Hypovitaminosis D is associated with psoriasis: a systematic review and meta-analysis","volume":"12","author":"Pitukweerakul","year":"2019","journal-title":"Kansas J Med"},{"key":"10.1016\/j.nut.2020.111024_bib0019","first-page":"339","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration","author":"Liberati","year":"2009","journal-title":"BMJ"},{"key":"10.1016\/j.nut.2020.111024_bib0020","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1159\/000250839","article-title":"Severe psoriasis\u2014oral therapy with a new retinoid","volume":"157","author":"Fredriksson","year":"1978","journal-title":"Dermatology"},{"key":"10.1016\/j.nut.2020.111024_bib0021","series-title":"Therapy for severe psoriasis","first-page":"17","article-title":"Ultraviolet B phototherapy","author":"Pena","year":"2017"},{"key":"10.1016\/j.nut.2020.111024_bib0022","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0197-2456(95)00134-4","article-title":"Assessing the quality of reports of randomized clinical trials: is blinding necessary?","volume":"17","author":"Jadad","year":"1996","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.nut.2020.111024_bib0023","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2: a revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"Br Med J"},{"key":"10.1016\/j.nut.2020.111024_bib0024","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.jclinepi.2010.04.026","article-title":"GRADE guidelines: 1. Introduction-GRADE evidence profiles and summary of findings tables","volume":"64","author":"Guyatt","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.nut.2020.111024_bib0025","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2288-14-135","article-title":"Estimating the sample mean and standard deviation from the sample size, median, range and\/or interquartile range","volume":"14","author":"Wan","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.nut.2020.111024_bib0026","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/0895-4356(92)90054-Q","article-title":"Variance imputation for overviews of clinical trials with continuous response","volume":"45","author":"Follmann","year":"1992","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.nut.2020.111024_bib0027","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/jrsm.1164","article-title":"Methods to estimate the between-study variance and its uncertainty in meta-analysis","volume":"7","author":"Veroniki","year":"2016","journal-title":"Res Synth Methods"},{"key":"10.1016\/j.nut.2020.111024_bib0028","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/1471-2288-14-25","article-title":"The Hartung-Knapp-Sidik-Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian-Laird method","volume":"14","author":"IntHout","year":"2014","journal-title":"BMC Med Res Methodol"},{"key":"10.1016\/j.nut.2020.111024_bib0029","series-title":"Cochrane handbook of systematic reviews of interventions","first-page":"241","article-title":"Analysing data and undertaking meta\u2010analyses","year":"2019"},{"key":"10.1016\/j.nut.2020.111024_bib0030","first-page":"40","article-title":"meta: An R package for meta-analysis","volume":"7","author":"Schwarzer","year":"2007","journal-title":"R News"},{"key":"10.1016\/j.nut.2020.111024_bib0031","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1080\/09546634.2017.1373735","article-title":"A randomized, double-blind, placebo-controlled trial of the effect of monthly vitamin D supplementation in mild psoriasis*","volume":"29","author":"Jarrett","year":"2018","journal-title":"J Dermatolog Treat"},{"key":"10.1016\/j.nut.2020.111024_bib0032","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1080\/09546634.2018.1444728","article-title":"Oral vitamin D3 supplementation for chronic plaque psoriasis: a randomized, double-blind, placebo-controlled trial","volume":"29","author":"Ingram","year":"2018","journal-title":"J Dermatolog Treat"},{"key":"10.1016\/j.nut.2020.111024_bib0033","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/5237642","article-title":"The clinical effect of oral vitamin D2 supplementation on psoriasis: a double-blind, randomized, placebo-controlled study","volume":"2019","author":"Disphanurat","year":"2019","journal-title":"Dermatol Res Pract"},{"key":"10.1016\/j.nut.2020.111024_bib0034","doi-asserted-by":"crossref","first-page":"243","DOI":"10.3109\/09546639009086743","article-title":"Vitamin D3 and psoriasis: a randomized double-blind placebo-controlled study","volume":"1","author":"Siddiqui","year":"1990","journal-title":"J Dermatolog Treat"},{"key":"10.1016\/j.nut.2020.111024_bib0035","first-page":"1070","article-title":"Safety and efficacy of oral calcitriol (1.25-dihydroxyvitamin D3) for the treatment of psoriasis","volume":"134","author":"Perez","year":"1996","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0036","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF02555120","article-title":"Treatment of psoriasis vulgaris by oral administration of 1 alpha-hydroxyvitamin D3\u2013open-design study","volume":"39","author":"Morimoto","year":"1986","journal-title":"Calcif Tissue Int"},{"key":"10.1016\/j.nut.2020.111024_bib0037","doi-asserted-by":"crossref","first-page":"1716","DOI":"10.1111\/1471-0528.15199","article-title":"Randomised controlled trials\u2014the gold standard for effectiveness research: Study design: randomised controlled trials","volume":"125","author":"Hariton","year":"2018","journal-title":"BJOG An Int J Obstet Gynaecol"},{"key":"10.1016\/j.nut.2020.111024_bib0038","doi-asserted-by":"crossref","DOI":"10.5070\/D3252042883","article-title":"Diet and psoriasis","volume":"25","author":"Pona","year":"2019","journal-title":"Dermatol Online J"},{"key":"10.1016\/j.nut.2020.111024_bib0039","doi-asserted-by":"crossref","first-page":"1807","DOI":"10.3389\/fimmu.2019.01807","article-title":"Psoriasis: obesity and fatty acids","volume":"10","author":"Kunz","year":"2019","journal-title":"Front Immunol"},{"key":"10.1016\/j.nut.2020.111024_bib0040","doi-asserted-by":"crossref","first-page":"138","DOI":"10.23736\/S0391-1977.20.03190-9","article-title":"Vitamin D and psoriasis: an update for dermatologists and nutritionists","volume":"45","author":"Megna","year":"2020","journal-title":"Minerva Endocrinol"},{"key":"10.1016\/j.nut.2020.111024_bib0041","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ad.2012.08.003","article-title":"Obesity and psoriasis: inflammatory nature of obesity, relationship between psoriasis and obesity, and therapeutic implications","volume":"105","author":"Carrascosa","year":"2014","journal-title":"Actas Dermosifiliogr"},{"key":"10.1016\/j.nut.2020.111024_bib0042","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0006340","article-title":"Vitamin D analogs differentially control antimicrobial peptide\/\u201calarmin\u201d expression in psoriasis","volume":"4","author":"Peric","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.nut.2020.111024_bib0043","doi-asserted-by":"crossref","first-page":"116","DOI":"10.4103\/0019-5154.127668","article-title":"Immunomodulatory mechanisms of action of calcitriol in psoriasis","volume":"59","author":"Raychaudhuri","year":"2014","journal-title":"Indian J Dermatol"},{"key":"10.1016\/j.nut.2020.111024_bib0044","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1111\/j.1468-3083.2012.04524.x","article-title":"Topical vitamin D analogues alone or in association with topical steroids for psoriasis: a systematic review","volume":"26","author":"Devaux","year":"2012","journal-title":"J Eur Acad Dermatology Venereol"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900720303075?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900720303075?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T12:13:54Z","timestamp":1760271234000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900720303075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":44,"alternative-id":["S0899900720303075"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2020.111024","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2021,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of oral vitamin D supplementation in lessening disease severity among patients with psoriasis: A systematic review and meta-analysis of randomized controlled trials","name":"articletitle","label":"Article Title"},{"value":"Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nut.2020.111024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111024"}}