{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:41:21Z","timestamp":1790617281481,"version":"4.1.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1016\/j.nut.2021.111261","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T12:22:11Z","timestamp":1617798131000},"page":"111261","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"special_numbering":"C","title":["Improvement of nutritional status enhances cognitive and physical functions in older adults with orthostatic hypotension"],"prefix":"10.1016","volume":"90","author":[{"given":"Suleyman Emre","family":"Kocyigit","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Ates Bulut","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0182-2850","authenticated-orcid":false,"given":"Ali Ekrem","family":"Aydin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Professor","given":"Ahmet Turan","family":"Isik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2021.111261_bib0001","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.maturitas.2013.07.013","article-title":"Malnutrition in the elderly: A narrative review","volume":"76","author":"Agarwal","year":"2013","journal-title":"Maturitas"},{"key":"10.1016\/j.nut.2021.111261_bib0002","doi-asserted-by":"crossref","first-page":"824","DOI":"10.1016\/j.jand.2014.11.010","article-title":"Differentiating malnutrition screening and assessment: A nutrition care process perspective","volume":"115","author":"Field","year":"2015","journal-title":"J Acad Nutr Diet"},{"key":"10.1016\/j.nut.2021.111261_bib0003","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/S0749-0690(02)00059-9","article-title":"Identifying the elderly at risk for malnutrition. The Mini Nutritional Assessment","volume":"18","author":"Guigoz","year":"2002","journal-title":"Clin Geriat Med"},{"key":"10.1016\/j.nut.2021.111261_bib0004","first-page":"456","article-title":"Overview of the MNA\u2013Its history and challenges","volume":"10","author":"Vellas","year":"2006","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.nut.2021.111261_bib0005","doi-asserted-by":"crossref","first-page":"1470","DOI":"10.1212\/WNL.46.5.1470","article-title":"Consensus statement on the definition of orthostatic hypotension, pure autonomic failure, and multiple system atrophy. The Consensus Committee of the American Autonomic Society and the American Academy of Neurology","volume":"46","year":"1996","journal-title":"Neurology"},{"key":"10.1016\/j.nut.2021.111261_bib0006","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/MBP.0000000000000466","article-title":"Postural blood pressure changes in the elderly: Orthostatic hypotension and hypertension","volume":"25","author":"Kocyigit","year":"2020","journal-title":"Blood Press Monit"},{"key":"10.1016\/j.nut.2021.111261_bib0007","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1007\/s12603-017-0953-9","article-title":"Orthostatic hypotension and associated factors among home care clients aged 75 years or older - A population-based study","volume":"22","author":"Luukkonen","year":"2018","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.nut.2021.111261_bib0008","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1007\/s12603-018-1032-6","article-title":"Malnutrition and malnutrition risk can be associated with systolic orthostatic hypotension in older adults","volume":"22","author":"Kocyigit","year":"2018","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.nut.2021.111261_bib0009","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1017\/S0029665118002628","article-title":"Malnutrition in older adults: Screening and determinants","volume":"78","author":"Corish","year":"2019","journal-title":"Proc Nutr Soc"},{"key":"10.1016\/j.nut.2021.111261_bib0010","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.jash.2011.08.008","article-title":"Orthostatic hypotension: A common, serious and underrecognized problem in hospitalized patients","volume":"6","author":"Feldstein","year":"2012","journal-title":"J Am Soc Hypertens"},{"key":"10.1016\/j.nut.2021.111261_bib0011","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1007\/s41999-019-00239-4","article-title":"Orthostatic hypotension and health outcomes: An umbrella review of observational studies","volume":"10","author":"Soysal","year":"2019","journal-title":"Eur Geriatr Med"},{"key":"10.1016\/j.nut.2021.111261_bib0012","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1093\/ageing\/afaa077","article-title":"Relationship between sarcopenia and orthostatic hypotension","volume":"49","author":"Soysal","year":"2020","journal-title":"Age Ageing"},{"key":"10.1016\/j.nut.2021.111261_bib0013","first-page":"272","article-title":"What is the relationship between frailty and orthostatic hypotension in older adults?","volume":"16","author":"Kocyigit","year":"2019","journal-title":"J Geriatr Cardiol"},{"key":"10.1016\/j.nut.2021.111261_bib0014","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1161\/HYPERTENSIONAHA.110.156380","article-title":"Orthostatic hypotension and incident chronic kidney disease: The atherosclerosis risk in communities study","volume":"56","author":"Franceschini","year":"2010","journal-title":"Hypertension"},{"key":"10.1016\/j.nut.2021.111261_bib0015","doi-asserted-by":"crossref","first-page":"1749","DOI":"10.1007\/s40520-019-01448-4","article-title":"Validation of population-based cutoffs for low muscle mass and strength in a population of Turkish elderly adults","volume":"32","author":"Ates Bulut","year":"2020","journal-title":"Aging Clin Exp Res"},{"key":"10.1016\/j.nut.2021.111261_bib0016","doi-asserted-by":"crossref","first-page":"M146","DOI":"10.1093\/gerona\/56.3.M146","article-title":"Frailty in older adults: Evidence for a phenotype","volume":"56","author":"Fried","year":"2001","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.nut.2021.111261_bib0017","doi-asserted-by":"crossref","first-page":"607","DOI":"10.2147\/CIA.S159966","article-title":"Costs of medication in older patients: Before and after comprehensive geriatric assessment","volume":"13","author":"Unutmaz","year":"2018","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.nut.2021.111261_bib0018","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1136\/hrt.2007.136457","article-title":"The Newcastle protocols 2008: An update on head-up tilt table testing and the management of vasovagal syncope and related disorders","volume":"95","author":"Parry","year":"2009","journal-title":"Heart"},{"key":"10.1016\/j.nut.2021.111261_bib0019","first-page":"168","article-title":"New horizons in orthostatic hypotension","volume":"46","author":"Frith","year":"2017","journal-title":"Age Ageing"},{"key":"10.1016\/j.nut.2021.111261_bib0020","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1161\/HYPERTENSIONAHA.119.14309","article-title":"Orthostatic hypotension, cardiovascular outcomes, and adverse events: Results from SPRINT","volume":"75","author":"Juraschek","year":"2020","journal-title":"Hypertension"},{"key":"10.1016\/j.nut.2021.111261_bib0021","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0192895","article-title":"Cardiovascular disease risk factors in chronic kidney disease: A systematic review and meta-analysis","volume":"13","author":"Major","year":"2018","journal-title":"PloS One"},{"key":"10.1016\/j.nut.2021.111261_bib0022","doi-asserted-by":"crossref","first-page":"1899","DOI":"10.2147\/CIA.S180281","article-title":"Frequency and coincidence of geriatric syndromes according to age groups: Single-center experience in Turkey between 2013 and 2017","volume":"13","author":"Ates Bulut","year":"2018","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.nut.2021.111261_bib0023","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.cger.2015.04.009","article-title":"Screening for malnutrition in older people","volume":"31","author":"Guyonnet","year":"2015","journal-title":"Clin Geriatr Med"},{"key":"10.1016\/j.nut.2021.111261_bib0024","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1016\/j.nephro.2017.01.003","article-title":"Orthostatic hypotension: A review","volume":"13","author":"Joseph","year":"2017","journal-title":"Nephrol Ther"},{"key":"10.1016\/j.nut.2021.111261_bib0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2019.06.001","article-title":"A comparison of the prevalence of orthostatic hypotension between older patients with Alzheimer's Disease, Lewy body dementia, and without dementia","volume":"124","author":"Isik","year":"2019","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.nut.2021.111261_bib0026","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3233\/JAD-190402","article-title":"Orthostatic hypotension: An important risk factor for clinical progression to mild cognitive impairment or dementia. The Amsterdam Dementia Cohort","volume":"71","author":"Kleipool","year":"2019","journal-title":"J Alzheimers Dis"},{"key":"10.1016\/j.nut.2021.111261_bib0027","doi-asserted-by":"crossref","first-page":"3135","DOI":"10.1093\/eurheartj\/ehy418","article-title":"Orthostatic hypotension and symptomatic subclinical orthostatic hypotension increase risk of cognitive impairment: An integrated evidence review and analysis of a large older adult hypertensive cohort","volume":"39","author":"Peters","year":"2018","journal-title":"Eur Heart J"},{"key":"10.1016\/j.nut.2021.111261_bib0028","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/jgs.14563","article-title":"Impaired orthostatic blood pressure recovery is associated with unexplained and injurious falls","volume":"65","author":"Finucane","year":"2017","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.nut.2021.111261_bib0029","doi-asserted-by":"crossref","first-page":"1609","DOI":"10.1093\/eurheartj\/ehv093","article-title":"Cardiovascular morbidity and mortality related to orthostatic hypotension: A meta-analysis of prospective observational studies","volume":"36","author":"Ricci","year":"2015","journal-title":"Eur Heart J"},{"key":"10.1016\/j.nut.2021.111261_bib0030","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.arr.2018.10.007","article-title":"Orthostatic hypotension and physical functioning in older adults: A systematic review and meta-analysis","volume":"48","author":"Mol","year":"2018","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.nut.2021.111261_bib0031","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s12603-019-1201-2","article-title":"Health and functional determinants of orthostatic hypotension in geriatric ward patients: A retrospective cross sectional cohort study","volume":"23","author":"Wojszel","year":"2019","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.nut.2021.111261_bib0032","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1179\/2295333715Y.0000000006","article-title":"Orthostatic hypotension and associated conditions in geriatric inpatients","volume":"70","author":"Jodaitis","year":"2015","journal-title":"Acta Clin Belg"},{"key":"10.1016\/j.nut.2021.111261_bib0033","first-page":"1","article-title":"Nutrition and aging successfully","volume":"20","author":"Morley","year":"2017","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.nut.2021.111261_bib0034","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1111\/jgs.16132","article-title":"Associations between skeletal muscle and myocardium in aging: A syndrome of \"cardio-sarcopenia\"?","volume":"67","author":"Keng","year":"2019","journal-title":"J Am Geriatr Soc"},{"key":"10.1016\/j.nut.2021.111261_bib0035","doi-asserted-by":"crossref","first-page":"693","DOI":"10.2147\/CIA.S196770","article-title":"Mini Nutritional Assessment Scale-Short Form can be useful for frailty screening in older adults","volume":"14","author":"Soysal","year":"2019","journal-title":"Clin Interv Aging"},{"key":"10.1016\/j.nut.2021.111261_bib0036","doi-asserted-by":"crossref","first-page":"1991","DOI":"10.3390\/nu11091991","article-title":"Efficacy of nutritional interventions as stand-alone or synergistic treatments with exercise for the management of sarcopenia","volume":"11","author":"Damanti","year":"2019","journal-title":"Nutrients"},{"key":"10.1016\/j.nut.2021.111261_bib0037","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1037\/0894-4105.20.2.215","article-title":"Cognitive processes related to gait velocity: Results from the Einstein Aging Study","volume":"20","author":"Holtzer","year":"2006","journal-title":"Neuropsychology"},{"key":"10.1016\/j.nut.2021.111261_bib0038","doi-asserted-by":"crossref","first-page":"1929","DOI":"10.3390\/nu12071929","article-title":"NHANES 2011\u20132014 reveals cognition of US older adults may benefit from better adaptation to the Mediterranean diet","volume":"12","author":"Taylor","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.nut.2021.111261_bib0039","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1177\/1533317518822274","article-title":"Effect of vitamin D on cognitive functions in older adults: 24-week follow-up study","volume":"34","author":"Ates Bulut","year":"2019","journal-title":"Am J Alzheimers Dis Other Demen"},{"key":"10.1016\/j.nut.2021.111261_bib0040","doi-asserted-by":"crossref","first-page":"3756","DOI":"10.1016\/j.clnu.2020.04.003","article-title":"Long-term effects of vitamin D deficiency on gait and balance in the older adults","volume":"39","author":"Sahin Alak","year":"2020","journal-title":"Clin Nutr"},{"key":"10.1016\/j.nut.2021.111261_bib0041","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/HJH.0000000000000907","article-title":"Hypovitaminosis D and orthostatic hypotension: A systematic review and meta-analysis","volume":"34","author":"Ometto","year":"2016","journal-title":"J Hypertens"},{"key":"10.1016\/j.nut.2021.111261_bib0042","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s10286-004-0142-x","article-title":"Orthostatic tolerance in older patients with vitamin B12 deficiency before and after vitamin B12 replacement","volume":"14","author":"Moore","year":"2004","journal-title":"Clin Auton Res"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900721001234?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900721001234?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T12:15:18Z","timestamp":1760271318000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900721001234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10]]},"references-count":42,"alternative-id":["S0899900721001234"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2021.111261","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2021,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Improvement of nutritional status enhances cognitive and physical functions in older adults with orthostatic hypotension","name":"articletitle","label":"Article Title"},{"value":"Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nut.2021.111261","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"111261"}}