{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T09:31:15Z","timestamp":1780047075410,"version":"3.53.1"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.nut.2025.112769","type":"journal-article","created":{"date-parts":[[2025,3,17]],"date-time":"2025-03-17T03:59:43Z","timestamp":1742183983000},"page":"112769","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["The mediating role of perceived social isolation in feeding methods and depression among patients with dysphagia after ischemic stroke: A multicenter study"],"prefix":"10.1016","volume":"135","author":[{"given":"Hongji","family":"Zeng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weijia","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzhen","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changming","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-6079-5008","authenticated-orcid":false,"given":"Xi","family":"Zeng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2025.112769_bib0001","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2024.1292289","article-title":"Influence of comorbidity of chronic diseases on basic activities of daily living among older adults in China: a propensity score-matched study","volume":"12","author":"Zeng","year":"2024","journal-title":"Front Public Health"},{"issue":"3","key":"10.1016\/j.nut.2025.112769_bib0002","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1007\/s00415-021-10597-4","article-title":"The advances of post-stroke depression: 2021 update","volume":"269","author":"Guo","year":"2022","journal-title":"J Neurol"},{"key":"10.1016\/j.nut.2025.112769_bib0003","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.genhosppsych.2020.06.011","article-title":"Post-stroke depression: a 2020 updated review","volume":"66","author":"Medeiros","year":"2020","journal-title":"Gen Hosp Psychiat"},{"key":"10.1016\/j.nut.2025.112769_bib0004","doi-asserted-by":"crossref","DOI":"10.1038\/s41572-019-0118-8","article-title":"Ischaemic stroke","volume":"5","author":"Campbell","year":"2019","journal-title":"Nat Rev Dis Primers"},{"issue":"3","key":"10.1016\/j.nut.2025.112769_bib0005","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1161\/STROKEAHA.119.028337","article-title":"Review of perfusion imaging in acute ischemic stroke from time to tissue","volume":"51","author":"Demeestere","year":"2020","journal-title":"Stroke"},{"issue":"2","key":"10.1016\/j.nut.2025.112769_bib0006","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s00455-023-10613-x","article-title":"The cortical and subcortical neural control of swallowing: a narrative review","volume":"39","author":"Wei","year":"2024","journal-title":"Dysphagia"},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0007","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00455-022-10443-3","article-title":"Clinical predictors of dysphagia recovery after stroke: a systematic review","volume":"38","author":"D'Netto","year":"2023","journal-title":"Dysphagia"},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000324940","article-title":"MRI-based neuroanatomical predictors of dysphagia after acute ischemic stroke: a systematic review and meta-analysis","volume":"32","author":"Flowers","year":"2011","journal-title":"Cerebrovasc Dis"},{"key":"10.1016\/j.nut.2025.112769_bib0009","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.nut.2017.10.022","article-title":"Changes in nutritional state and dysphagia in stroke patients monitored during a 14-d period in a Burkina Faso hospital setting","volume":"48","author":"Diend\u00e9r\u00e9","year":"2018","journal-title":"Nutrition"},{"issue":"5","key":"10.1016\/j.nut.2025.112769_bib0010","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1044\/2022_JSLHR-21-00502","article-title":"Understanding the independent predictors of dysphagia-related quality of life in stroke survivors","volume":"65","author":"Namasivayam-MacDonald","year":"2022","journal-title":"J Speech Lang Hear R"},{"issue":"10","key":"10.1016\/j.nut.2025.112769_bib0011","doi-asserted-by":"crossref","first-page":"11191","DOI":"10.21037\/apm-21-2922","article-title":"Enteral nutrition management in stroke patients: a narrative review","volume":"10","author":"Gong","year":"2021","journal-title":"Ann Palliat Med"},{"key":"10.1016\/j.nut.2025.112769_bib0012","series-title":"Practical rehabilitation techniques for dysphagia","author":"Xi","year":"2020"},{"issue":"7","key":"10.1016\/j.nut.2025.112769_bib0013","doi-asserted-by":"crossref","first-page":"7406","DOI":"10.21037\/apm-21-736","article-title":"Intermittent tube feeding for stroke patients with dysphagia: a meta-analysis and systematic review","volume":"10","author":"Wu","year":"2021","journal-title":"Ann Palliat Med"},{"issue":"5","key":"10.1016\/j.nut.2025.112769_bib0014","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1161\/STROKEAHA.123.046122","article-title":"Effect of intermittent oro-esophageal tube feeding in bulbar palsy after ischemic stroke: a randomized controlled study","volume":"55","author":"Zeng","year":"2024","journal-title":"Stroke"},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0015","doi-asserted-by":"crossref","DOI":"10.12998\/wjcc.v12.i1.119","article-title":"Nasogastric tube syndrome: a meta-summary of case reports","volume":"12","author":"Juneja","year":"2024","journal-title":"World J Clin Cases"},{"key":"10.1016\/j.nut.2025.112769_bib0016","doi-asserted-by":"crossref","DOI":"10.1016\/j.nut.2024.112673","article-title":"Intermittent Oro-Esophageal tube feeding for cerebral small vessel disease patients with dysphagia: a randomized controlled study","author":"Zeng","year":"2025","journal-title":"Nutrition"},{"issue":"3","key":"10.1016\/j.nut.2025.112769_bib0017","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1192\/bjb.2023.58","article-title":"Nasogastric tube feeding under restraint: understanding the impact and improving care","volume":"48","author":"Fuller","year":"2024","journal-title":"Bjpsych Bull"},{"key":"10.1016\/j.nut.2025.112769_bib0018","article-title":"How tube feeding modes influence anxiety in patients with dysphagia after ischemic stroke: a propensity score matched, longitudinal study","author":"Zeng","year":"2024","journal-title":"Int J Stroke"},{"key":"10.1016\/j.nut.2025.112769_bib0019","series-title":"Dysphagia: Diagnosis and Treatment","first-page":"873","article-title":"Social and psychologic impact of dysphagia","author":"Pizzorni","year":"2019"},{"issue":"7","key":"10.1016\/j.nut.2025.112769_bib0020","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1016\/j.apmr.2024.02.733","article-title":"Dynamics of perceived social isolation, secondary conditions, and daily activity patterns among individuals with stroke: a network analysis of ecological momentary assessment data","volume":"105","author":"Shi","year":"2024","journal-title":"Arch Phys Med Rehab"},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0021","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.expneurol.2011.01.016","article-title":"Stress and social isolation increase vulnerability to stroke","volume":"233","author":"Stuller","year":"2012","journal-title":"Exp Neurol"},{"issue":"14","key":"10.1016\/j.nut.2025.112769_bib0022","doi-asserted-by":"crossref","first-page":"5895","DOI":"10.1073\/pnas.0810737106","article-title":"Social isolation alters neuroinflammatory response to stroke","volume":"106","author":"Karelina","year":"2009","journal-title":"P Natl Acad Sci Usa"},{"key":"10.1016\/j.nut.2025.112769_bib0023","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.bbr.2013.10.047","article-title":"Social isolation after stroke leads to depressive-like behavior and decreased BDNF levels in mice","volume":"260","author":"O'Keefe","year":"2014","journal-title":"Behav Brain Res"},{"issue":"9","key":"10.1016\/j.nut.2025.112769_bib0024","first-page":"710","article-title":"Diagnostic criteria of cerebrovascular diseases in China (version 2019)","volume":"52","author":"Neurology","year":"2019","journal-title":"Chin J Neurol"},{"issue":"4","key":"10.1016\/j.nut.2025.112769_bib0025","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1007\/s00455-019-10064-3","article-title":"Use of the penetration-aspiration scale in dysphagia research: a systematic review","volume":"35","author":"Borders","year":"2020","journal-title":"Dysphagia"},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0026","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1177\/0148607116673053","article-title":"ASPEN safe practices for enteral nutrition therapy","volume":"41","author":"Boullata","year":"2017","journal-title":"Jpen-Parenter Enter"},{"issue":"2","key":"10.1016\/j.nut.2025.112769_bib0027","first-page":"434","article-title":"Chinese expert consensus on food and nutrition management for dysphagia (2019 version)","volume":"29","author":"Chinese","year":"2020","journal-title":"Asia Pac J Clin Nutr"},{"issue":"10","key":"10.1016\/j.nut.2025.112769_bib0028","first-page":"1061","article-title":"New evidence, new guidelines, and new criteria for secondary prevention of ischemic stroke","volume":"55","author":"Wang","year":"2022","journal-title":"Chin J Neurol"},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0029","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1089\/heq.2022.0030","article-title":"Validity of the Chinese language patient health questionnaire 2 and 9: a systematic review","volume":"6","author":"Yin","year":"2022","journal-title":"Health Equity"},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0030","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1186\/s12955-022-01997-9","article-title":"Validity and reliability of the Chinese version of the patient-reported outcomes measurement information system adult profile-57 (PROMIS-57)","volume":"20","author":"Cai","year":"2022","journal-title":"Health Qual Life Out"},{"issue":"11","key":"10.1016\/j.nut.2025.112769_bib0031","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.117.008069","article-title":"Perceived social isolation and outcomes in patients with heart failure","volume":"7","author":"Manemann","year":"2024","journal-title":"J Am Heart Assoc"},{"issue":"11","key":"10.1016\/j.nut.2025.112769_bib0032","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0259806","article-title":"Changes in PHQ-9 depression scores in acute stroke patients shortly after returning home","volume":"16","author":"Strong","year":"2021","journal-title":"Plos One"},{"issue":"12","key":"10.1016\/j.nut.2025.112769_bib0033","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1093\/aje\/kwj149","article-title":"Variable selection for propensity score models","volume":"163","author":"Brookhart","year":"2006","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.nut.2025.112769_bib0034","article-title":"Reliability and validity of the Chinese Mandarin version of the dysphagia handicap index","author":"Zeng","year":"2024","journal-title":"Dysphagia."},{"issue":"12","key":"10.1016\/j.nut.2025.112769_bib0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.jamda.2024.105297","article-title":"Effect of simple swallowing training program on early oropharyngeal dysphagia in community-dwelling older adults: a randomized controlled study","volume":"25","author":"Zeng","year":"2024","journal-title":"J Am Med Dir Assoc"},{"issue":"4","key":"10.1016\/j.nut.2025.112769_bib0036","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1080\/09602011.2013.794742","article-title":"The influence of self-efficacy, pre-stroke depression and perceived social support on self-reported depressive symptoms during stroke rehabilitation","volume":"23","author":"Lewin","year":"2013","journal-title":"Neuropsychol Rehabil"},{"key":"10.1016\/j.nut.2025.112769_bib0037","series-title":"Principles of Deglutition: A Multidisciplinary Text for Swallowing and its Disorders","first-page":"965","article-title":"Tube feeding: indications, considerations, and technique","author":"Berger","year":"2013"},{"issue":"6","key":"10.1016\/j.nut.2025.112769_bib0038","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1111\/j.1600-0404.2010.01422.x","article-title":"Stress and depression symptoms in patients with multiple sclerosis: the mediating role of the loss of social functioning","volume":"123","author":"Kirchner","year":"2011","journal-title":"Acta Neurol Scand"},{"issue":"10","key":"10.1016\/j.nut.2025.112769_bib0039","first-page":"702","article-title":"How enteral nutrition modes influence nasopharyngeal carcinoma survivors with late dysphagia after radiotherapy: a randomized controlled study","volume":"32","author":"Zeng","year":"2024","journal-title":"Support Care Cancer"},{"issue":"06","key":"10.1016\/j.nut.2025.112769_bib0040","first-page":"296","article-title":"Effect of intermittent oral to esophageal feeding on stigma in patients with dysphagia after stroke","volume":"14","author":"Zhang","year":"2019","journal-title":"Neural Injury and Functional Reconstruction"},{"issue":"2","key":"10.1016\/j.nut.2025.112769_bib0041","first-page":"58","article-title":"Social relationships and health: the toxic effects of perceived social isolation","volume":"8","author":"Cacioppo","year":"2014","journal-title":"Soc Personal Psychol"},{"key":"10.1016\/j.nut.2025.112769_bib0042","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jad.2023.02.096","article-title":"Emotional and social loneliness and their unique links with social isolation, depression and anxiety","volume":"329","author":"Wolters","year":"2023","journal-title":"J Affect Disorders"},{"issue":"4","key":"10.1016\/j.nut.2025.112769_bib0043","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1002\/cpp.2061","article-title":"The Relationship between self-blame for the onset of a chronic physical health condition and emotional distress: a systematic literature review","volume":"24","author":"Callebaut","year":"2017","journal-title":"Clin Psychol Psychot"},{"issue":"6","key":"10.1016\/j.nut.2025.112769_bib0044","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1007\/s00455-016-9717-7","article-title":"Outcome of rehabilitation and swallowing therapy after percutaneous endoscopic gastrostomy in dysphagia patients","volume":"31","author":"Yoon","year":"2016","journal-title":"Dysphagia."},{"issue":"1","key":"10.1016\/j.nut.2025.112769_bib0045","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s41043-021-00264-9","article-title":"Clinician's attitude to enteral nutrition with percutaneous endoscopic gastrostomy: a survey in China","volume":"40","author":"Zhang","year":"2021","journal-title":"Journal of Health, Population and Nutrition."},{"issue":"2","key":"10.1016\/j.nut.2025.112769_bib0046","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.jfma.2012.04.002","article-title":"Percutaneous endoscopic gastrostomy placement: caregiver decision making in Taiwan","volume":"112","author":"Yeh","year":"2013","journal-title":"J Formos Med Assoc"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900725000875?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900725000875?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T04:32:55Z","timestamp":1762317175000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900725000875"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":46,"alternative-id":["S0899900725000875"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2025.112769","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The mediating role of perceived social isolation in feeding methods and depression among patients with dysphagia after ischemic stroke: A multicenter study","name":"articletitle","label":"Article Title"},{"value":"Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nut.2025.112769","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112769"}}