{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,15]],"date-time":"2026-07-15T16:28:08Z","timestamp":1784132888087,"version":"3.55.0"},"reference-count":31,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["22K11839"],"award-info":[{"award-number":["22K11839"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020685","name":"Japan Hospice Palliative Care Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100020685","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.nut.2025.112818","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T19:13:22Z","timestamp":1745608402000},"page":"112818","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Association between baseline inflammation and the effectiveness of nutritional support among terminally ill patients with cancer: A secondary analysis of a multicenter prospective cohort study"],"prefix":"10.1016","volume":"138","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1779-6389","authenticated-orcid":false,"given":"Koji","family":"Amano","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satomi","family":"Okamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0357-8604","authenticated-orcid":false,"given":"Naoharu","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuma","family":"Sakaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomofumi","family":"Miura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Uneno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroto","family":"Ishiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Hiratsuka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naosuke","family":"Yokomichi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0304-9881","authenticated-orcid":false,"given":"Jun","family":"Hamano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masanori","family":"Mori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatsuya","family":"Morita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nut.2025.112818_bib0001","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1200\/JCO.20.00611","article-title":"Management of cancer cachexia: ASCO guideline","volume":"38","author":"Roeland","year":"2020","journal-title":"J Clin Oncol"},{"issue":"3","key":"10.1016\/j.nut.2025.112818_bib0002","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2021.100092","article-title":"Cancer cachexia in adult patients: ESMO clinical practice guidelines","volume":"6","author":"Arends","year":"2021","journal-title":"ESMO Open"},{"issue":"5","key":"10.1016\/j.nut.2025.112818_bib0003","doi-asserted-by":"crossref","first-page":"2898","DOI":"10.1016\/j.clnu.2021.02.005","article-title":"ESPEN practical guideline: clinical nutrition in cancer","volume":"40","author":"Muscaritoli","year":"2021","journal-title":"Clin Nutr"},{"issue":"4","key":"10.1016\/j.nut.2025.112818_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.esmoop.2021.100225","article-title":"Care of the adult cancer patient at the end of life: ESMO clinical practice guidelines","volume":"6","author":"Crawford","year":"2021","journal-title":"ESMO Open"},{"key":"10.1016\/j.nut.2025.112818_bib0005","doi-asserted-by":"crossref","DOI":"10.1177\/1758835919899852","article-title":"Unmet needs in clinical nutrition in oncology: a multinational analysis of real-world evidence","volume":"12","author":"Caccialanza","year":"2020","journal-title":"Ther Adv Med Oncol"},{"issue":"3","key":"10.1016\/j.nut.2025.112818_bib0006","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1016\/j.clnu.2020.07.027","article-title":"Effects of enteral nutrition and parenteral nutrition on survival in patients with advanced cancer cachexia: analysis of a multicenter prospective cohort study","volume":"40","author":"Amano","year":"2021","journal-title":"Clin Nutr"},{"issue":"12","key":"10.1016\/j.nut.2025.112818_bib0007","first-page":"7541","article-title":"Effects of parenteral nutrition and hydration on survival in advanced cancer patients with malignant bowel obstruction: secondary analysis of a multicenter prospective cohort study","volume":"29","author":"Arakawa","year":"2021","journal-title":"Support Care Cancer"},{"issue":"11","key":"10.1016\/j.nut.2025.112818_bib0008","doi-asserted-by":"crossref","first-page":"3346","DOI":"10.1016\/j.clnu.2020.02.021","article-title":"Home artificial nutrition in palliative care cancer patients: impact on survival and performance status","volume":"39","author":"Ruggeri","year":"2020","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.nut.2025.112818_bib0009","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1136\/bmjspcare-2020-002343","article-title":"Home parenteral nutrition versus artificial hydration in malnourished patients with cancer in palliative care: a prospective, cohort survival study","volume":"12","author":"Cotogni","year":"2022","journal-title":"BMJ Support Palliat Care"},{"key":"10.1016\/j.nut.2025.112818_bib0010","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.clnu.2024.12.008","article-title":"Nutritional interventions in randomised clinical trials for people with incurable solid cancer: a systematic review","volume":"44","author":"Mcluskie","year":"2024","journal-title":"Clin Nutr"},{"issue":"1","key":"10.1016\/j.nut.2025.112818_bib0011","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/jcsm.12383","article-title":"GLIM criteria for the diagnosis of malnutrition\u2014a consensus report from the global clinical nutrition community","volume":"10","author":"Cederholm","year":"2019","journal-title":"J Cachexia Sarcopenia Muscle"},{"issue":"5","key":"10.1016\/j.nut.2025.112818_bib0012","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.clnu.2023.11.026","article-title":"Guidance for assessment of the inflammation etiologic criterion for the GLIM diagnosis of malnutrition: a modified Delphi approach","volume":"43","author":"Cederholm","year":"2024","journal-title":"Clin Nutr"},{"issue":"10188","key":"10.1016\/j.nut.2025.112818_bib0013","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1016\/S0140-6736(18)32776-4","article-title":"Individualised nutritional support in medical inpatients at nutritional risk: a randomised clinical trial","volume":"393","author":"Schuetz","year":"2019","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.nut.2025.112818_bib0014","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2020.0663","article-title":"Association of baseline inflammation with effectiveness of nutritional support among patients with disease-related malnutrition: a secondary analysis of a randomized clinical trial","volume":"3","author":"Merker","year":"2020","journal-title":"JAMA Netw Open"},{"issue":"1","key":"10.1016\/j.nut.2025.112818_bib0015","first-page":"50","article-title":"Enteral nutrition support in patients with cancer: association of short-term prognosis and medical costs with inflammation","volume":"33","author":"Liu","year":"2024","journal-title":"Support Care Cancer"},{"issue":"22","key":"10.1016\/j.nut.2025.112818_bib0016","doi-asserted-by":"crossref","first-page":"7988","DOI":"10.1002\/cam4.4314","article-title":"Diagnostic models for impending death in terminally ill cancer patients: a multicenter cohort study","volume":"10","author":"Mori","year":"2021","journal-title":"Cancer Med"},{"issue":"6","key":"10.1016\/j.nut.2025.112818_bib0017","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/jjco\/hyac034","article-title":"Overview of the ethical guidelines for medical and biological research involving human subjects in Japan","volume":"52","author":"Eba","year":"2022","journal-title":"Jpn J Clin Oncol"},{"issue":"6","key":"10.1016\/j.nut.2025.112818_bib0018","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1097\/00000421-198212000-00014","article-title":"Toxicity and response criteria of the eastern cooperative oncology group","volume":"5","author":"Oken","year":"1982","journal-title":"Am J Clin Oncol"},{"issue":"3","key":"10.1016\/j.nut.2025.112818_bib0019","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1093\/jjco\/hyy203","article-title":"Validation of the integrated palliative care outcome scale (IPOS)\u2014Japanese version","volume":"49","author":"Sakurai","year":"2019","journal-title":"Jpn J Clin Oncol"},{"key":"10.1016\/j.nut.2025.112818_bib0020","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1038\/nature07205","article-title":"Cancer-related inflammation","volume":"454","author":"Mantovani","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.nut.2025.112818_bib0021","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S1470-2045(10)70218-7","article-title":"Definition and classification of cancer cachexia: an international consensus","volume":"12","author":"Fearon","year":"2011","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.nut.2025.112818_bib0022","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/S1470-2045(12)70582-X","article-title":"Cytokine patterns in patients with cancer: a systematic review","volume":"14","author":"Lippitz","year":"2013","journal-title":"Lancet Oncol"},{"issue":"suppl 1","key":"10.1016\/j.nut.2025.112818_bib0023","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1007\/s10875-012-9847-0","article-title":"Cancer-related inflammation","volume":"33","author":"Candido","year":"2013","journal-title":"J Clin Immunol"},{"key":"10.1016\/j.nut.2025.112818_bib0024","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S1470-2045(14)70263-3","article-title":"Cancer-related inflammation and treatment effectiveness","volume":"15","author":"Diakos","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.nut.2025.112818_bib0025","doi-asserted-by":"crossref","first-page":"17105","DOI":"10.1038\/nrdp.2017.105","article-title":"Cancer-associated cachexia","volume":"4","author":"Baracos","year":"2018","journal-title":"Nat Rev Dis Primers"},{"issue":"9","key":"10.1016\/j.nut.2025.112818_bib0026","doi-asserted-by":"crossref","first-page":"1824","DOI":"10.1016\/j.cell.2023.03.028","article-title":"Cachexia: a systemic consequence of progressive, unresolved disease","volume":"186","author":"Ferrer","year":"2023","journal-title":"Cell"},{"issue":"6","key":"10.1016\/j.nut.2025.112818_bib0027","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.clnu.2022.04.019","article-title":"Inflammatory burden as a prognostic biomarker for cancer","volume":"41","author":"Xie","year":"2022","journal-title":"Clin Nutr"},{"issue":"11","key":"10.1016\/j.nut.2025.112818_bib0028","doi-asserted-by":"crossref","first-page":"3471","DOI":"10.3390\/ijms19113471","article-title":"Efficacy of anamorelin, a novel non-peptide ghrelin analogue, in patients with advanced non-small cell lung cancer (NSCLC) and cachexia-review and expert opinion","volume":"19","author":"Currow","year":"2018","journal-title":"Int J Mol Sci"},{"issue":"3","key":"10.1016\/j.nut.2025.112818_bib0029","doi-asserted-by":"crossref","DOI":"10.4088\/JCP.24f15532","article-title":"Therapeutic effects, side effects, and adverse effects of neuropsychiatric drugs in the context of treating cancer-related anorexia with olanzapine and mirtazapine","volume":"85","author":"Andrade","year":"2024","journal-title":"J Clin Psychiatry"},{"issue":"24","key":"10.1016\/j.nut.2025.112818_bib0030","doi-asserted-by":"crossref","first-page":"2291","DOI":"10.1056\/NEJMoa2409515","article-title":"Ponsegromab for the treatment of cancer cachexia","volume":"391","author":"Groarke","year":"2024","journal-title":"N Engl J Med"},{"issue":"1","key":"10.1016\/j.nut.2025.112818_bib0031","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1038\/s41571-024-00964-1","article-title":"On the cusp of targeted therapy for cancer cachexia\u2014what clinical benefits might we promise our patients?","volume":"22","author":"Baracos","year":"2025","journal-title":"Nat Rev Clin Oncol"}],"container-title":["Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900725001364?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0899900725001364?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T04:32:27Z","timestamp":1762317147000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0899900725001364"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":31,"alternative-id":["S0899900725001364"],"URL":"https:\/\/doi.org\/10.1016\/j.nut.2025.112818","relation":{},"ISSN":["0899-9007"],"issn-type":[{"value":"0899-9007","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Association between baseline inflammation and the effectiveness of nutritional support among terminally ill patients with cancer: A secondary analysis of a multicenter prospective cohort study","name":"articletitle","label":"Article Title"},{"value":"Nutrition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nut.2025.112818","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"112818"}}