{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T23:45:59Z","timestamp":1790466359070,"version":"4.1.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2012,8,1]],"date-time":"2012-08-01T00:00:00Z","timestamp":1343779200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nutrition Research"],"published-print":{"date-parts":[[2012,8]]},"DOI":"10.1016\/j.nutres.2012.06.015","type":"journal-article","created":{"date-parts":[[2012,8,3]],"date-time":"2012-08-03T03:01:17Z","timestamp":1343962877000},"page":"626-636","source":"Crossref","is-referenced-by-count":33,"title":["Aqueous extract of tamarind seeds selectively increases glucose transporter-2, glucose transporter-4, and islets' intracellular calcium levels and stimulates \u03b2-cell proliferation resulting in improved glucose homeostasis in rats with streptozotocin-induced diabetes mellitus"],"prefix":"10.1016","volume":"32","author":[{"given":"Sushant Shivdas","family":"Sole","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.P.","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nutres.2012.06.015_bb0005","first-page":"732","article-title":"Role of hemeoxygenase in inflammation insulin signaling diabetes and obesity","volume":"359","author":"Ndsing","year":"2010","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.nutres.2012.06.015_bb0010","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1073\/pnas.86.8.2535","article-title":"A glucose transport protein expressed predominantly in insulin-responsive tissues","volume":"86","author":"Charron","year":"1989","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.nutres.2012.06.015_bb0015","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1056\/NEJM199907223410406","article-title":"Glucose transporters and insulin action: implications for insulin resistance and diabetes mellitus","volume":"341","author":"Shepherd","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nutres.2012.06.015_bb0020","doi-asserted-by":"crossref","first-page":"198","DOI":"10.2337\/diacare.13.3.198","article-title":"Molecular biology of mammalian glucose transporters","volume":"13","author":"Bell","year":"1990","journal-title":"Diabetes Care"},{"key":"10.1016\/j.nutres.2012.06.015_bb0025","doi-asserted-by":"crossref","first-page":"13656","DOI":"10.1073\/pnas.96.24.13656","article-title":"Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocininduced, diabetes","volume":"96","author":"Shimomura","year":"1999","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.nutres.2012.06.015_bb0030","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1152\/physrev.1987.67.4.1185","article-title":"Ca2+, cAMP, and phospholipid-derived messengers in coupling mechanisms of insulin secretion","volume":"67","author":"Prentki","year":"1987","journal-title":"Physiol Rev"},{"key":"10.1016\/j.nutres.2012.06.015_bb0035","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1006\/niox.1998.0203","article-title":"Insulin secretion DNA damage and apoptosis in human and rat islets following exposure to nitric oxide, peroxynitrite and cytokines","volume":"2","author":"Hadjivassiliou","year":"1998","journal-title":"Nitric Oxide"},{"key":"10.1016\/j.nutres.2012.06.015_bb0040","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.fct.2003.12.001","article-title":"Extract of seed coat of Tamarindus indica L. Inhibits nitric oxide production by murine macrophages in vitro and in vivo","volume":"42","author":"Komutarin","year":"2004","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.nutres.2012.06.015_bb0045","doi-asserted-by":"crossref","first-page":"2671","DOI":"10.1021\/jf00048a004","article-title":"Antioxidative components isolated from the seed of Tamarind (Tamarindus indica L)","volume":"42","author":"Tsuda","year":"1994","journal-title":"Agric Food Chem"},{"key":"10.1016\/j.nutres.2012.06.015_bb0050","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1002\/ptr.2650090316","article-title":"Screening of antiradical, antilipoperoxidant and hepatotoprotective effects of nine plant extracts used in Caribbean folk medicine","volume":"9","author":"Joyeux","year":"1995","journal-title":"Phytother Res"},{"key":"10.1016\/j.nutres.2012.06.015_bb0055","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1002\/(SICI)1099-1573(199903)13:2<128::AID-PTR399>3.0.CO;2-7","article-title":"Antiinflammatory activity of some extracts from plants used in traditional medicines of North-African Countries (II)","volume":"13","author":"Rimbau","year":"1999","journal-title":"Phytother Res"},{"key":"10.1016\/j.nutres.2012.06.015_bb0060","first-page":"235","article-title":"Tamarindus indica Linn","volume":"Vol. 5","author":"Iyer","year":"1995"},{"key":"10.1016\/j.nutres.2012.06.015_bb0065","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1248\/bpb.28.1172","article-title":"Attenuation of hyperglycemia and hyperlipidemia in streptozotocin induced diabetic rats by aqueous extract of seed of Tamarindus indica","volume":"28","author":"Maiti","year":"2005","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.nutres.2012.06.015_bb0070","series-title":"Orientation training course on research methodology in reproductive biomedicine","author":"Khillare","year":"2000"},{"key":"10.1016\/j.nutres.2012.06.015_bb0075","first-page":"590","article-title":"Islet secretion in new experimental model of non-insulin dependent diabetes","volume":"30","author":"Weir","year":"1981","journal-title":"Diabetes Metab Rev"},{"key":"10.1016\/j.nutres.2012.06.015_bb0080","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1177\/29.4.6166661","article-title":"Use of avidin-biotin peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabelled antibody (PAP) procedures","volume":"29","author":"Hsu","year":"1981","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.nutres.2012.06.015_bb0085","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0041-1345(96)00055-3","article-title":"Fas antigen expression and apoptosis in kidney allografts","volume":"29","author":"Matsuno","year":"1997","journal-title":"Transplant Proc"},{"key":"10.1016\/j.nutres.2012.06.015_bb0090","doi-asserted-by":"crossref","first-page":"35","DOI":"10.2337\/diab.16.1.35","article-title":"Method for the isolation of intact islets of Langerhans from the rat pancreas","volume":"16","author":"Lacy","year":"1967","journal-title":"Diabetes"},{"key":"10.1016\/j.nutres.2012.06.015_bb0095","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/0003-9861(91)90192-L","article-title":"Continuous measurement of mitochondrial pH gradients in isolated hepatocytes by difference ratio spectroscopy","volume":"288","author":"Thomas","year":"1991","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.nutres.2012.06.015_bb0100","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1677\/jme.1.01679","article-title":"Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats","volume":"34","author":"Suh","year":"2005","journal-title":"J Mol Endocrinol"},{"key":"10.1016\/j.nutres.2012.06.015_bb0105","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1248\/bpb.30.1015","article-title":"Effects of Hachimi-jio-gan (Ba-Wei-Di-Huang-Wan) on hyperglycemia in streptozotocin induced diabetic rats","volume":"30","author":"Yoshihiko","year":"2007","journal-title":"Biol Pharm Bull"},{"key":"10.1016\/j.nutres.2012.06.015_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.etp.2011.01.003","article-title":"Abresham ameliorates dyslipidemia,hepaticsteatosis and hypertension in high fat diet fed rats by repressing oxidative stress, TNF-\u03b1 and normalizing NO production","author":"Nepal","year":"2011","journal-title":"Exp Toxicol Pathol"},{"key":"10.1016\/j.nutres.2012.06.015_bb0115","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.cccn.2004.01.019","article-title":"The effect of estrogen on serum nitric oxide concentrations in normotensive and DOCA salt hypertensive ovariectomized rats","volume":"344","author":"Nematbakhsh","year":"2004","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.nutres.2012.06.015_bb0120","first-page":"991","article-title":"Development and standardization of a new immunoturbidimetric assay HbA1c Assay","volume":"39","author":"Karl","year":"1993","journal-title":"Klin Lab"},{"key":"10.1016\/j.nutres.2012.06.015_bb0125","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1073\/pnas.93.3.1049","article-title":"Sterol regulation of acetyl coenzyme A carboxylase: a mechanism for coordinate control of cellular lipid","volume":"93","author":"Lopez","year":"1996","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.nutres.2012.06.015_bb0130","doi-asserted-by":"crossref","first-page":"e73","DOI":"10.1093\/nar\/gng073","article-title":"Experimental validation of novel and conventional approaches to quantitative real-timePCR data analysis","volume":"31","author":"Peirson","year":"2003","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.nutres.2012.06.015_bb0135","doi-asserted-by":"crossref","first-page":"1210","DOI":"10.2337\/diabetes.42.8.1210","article-title":"Fluorescence digital image analysis of glucose-induced [Ca2+]i oscillations in mouse pancreatic islets of Langerhans","volume":"42","author":"Valdeolmillos","year":"1993","journal-title":"Diabetes"},{"key":"10.1016\/j.nutres.2012.06.015_bb0140","doi-asserted-by":"crossref","first-page":"764","DOI":"10.2337\/diab.36.6.764","article-title":"Pulsatile secretion of fuel-regulatory hormones","volume":"36","author":"Weigle","year":"1987","journal-title":"Diabetes"},{"key":"10.1016\/j.nutres.2012.06.015_bb0145","first-page":"129","article-title":"Inhibition of metallopeptidases by flavonoids and related compounds","volume":"55","author":"Borman","year":"2000","journal-title":"Die Pharmazie"},{"key":"10.1016\/j.nutres.2012.06.015_bb0150","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/0196-9781(90)90135-R","article-title":"Distribution of neuropeptide-Y and vasoactive intestinal polypeptide immunoreactive nerves in normal and transplanted pancreatic tissue","volume":"11","author":"Adeghate","year":"1990","journal-title":"Peptides"},{"key":"10.1016\/j.nutres.2012.06.015_bb0155","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1196\/annals.1433.001","article-title":"Usefulness of antibodies for evaluating the biological significance of AGEs","volume":"1126","author":"Nagai","year":"2008","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.nutres.2012.06.015_bb0160","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2174\/138161210789941838","article-title":"Nitrosative stress as a mediator of apoptosis: implications for cancer therapy","volume":"16","author":"Hirst","year":"2010","journal-title":"Curr Pharm Des"},{"key":"10.1016\/j.nutres.2012.06.015_bb0165","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0940-9602(11)80189-5","article-title":"Differential proliferation of somatostatin and glucagons cells in rat pancreatic islets submitted to different stimuli","volume":"177","author":"Pons","year":"1995","journal-title":"Ann Anat"},{"key":"10.1016\/j.nutres.2012.06.015_bb0170","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1074\/jbc.274.6.3253","article-title":"GLUT 4 gene regulation and manipulation","volume":"274","author":"Charron","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.nutres.2012.06.015_bb0175","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1172\/JCI115858","article-title":"The loss of GLUT2 expression by glucose unresponsive beta cells of db\/db mice is reversible and is induced by the diabetic environment","volume":"90","author":"Thorens","year":"1992","journal-title":"J Clin Invest"},{"key":"10.1016\/j.nutres.2012.06.015_bb0180","doi-asserted-by":"crossref","first-page":"2791","DOI":"10.1172\/JCI28570.","article-title":"TNF-\u03b1 downregulates eNOS expression and mitochondrial biogenesis in fat and muscle of obese rodents","volume":"116","author":"Valerio","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.nutres.2012.06.015_bb0185","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.fct.2005.10.011","article-title":"Hypolipemic and antioxidant activities from Tamarindus indica L. pulp fruit extract in hypercholesterolemic hamsters","volume":"44","author":"Martinello","year":"2006","journal-title":"Food Chem Toxicol"}],"container-title":["Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027153171200142X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S027153171200142X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,2]],"date-time":"2019-07-02T08:49:10Z","timestamp":1562057350000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S027153171200142X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2012,8]]}},"alternative-id":["S027153171200142X"],"URL":"https:\/\/doi.org\/10.1016\/j.nutres.2012.06.015","relation":{},"ISSN":["0271-5317"],"issn-type":[{"value":"0271-5317","type":"print"}],"subject":[],"published":{"date-parts":[[2012,8]]}}}