{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,6]],"date-time":"2025-12-06T04:57:30Z","timestamp":1764997050110},"reference-count":31,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270449"],"award-info":[{"award-number":["81270449"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Shandong Provincial Natural Science Foundation, China","award":["ZR2012HM046"],"award-info":[{"award-number":["ZR2012HM046"]}]},{"name":"Qingdao Minsheng Science and Technology Foundation, Shandong, China","award":["14-2-3-5-nsh"],"award-info":[{"award-number":["14-2-3-5-nsh"]}]},{"name":"Qingdao Science and Technology Plan Project","award":["13-1-4-220-jch"],"award-info":[{"award-number":["13-1-4-220-jch"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.es","nrjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition Research"],"published-print":{"date-parts":[[2015,9]]},"DOI":"10.1016\/j.nutres.2015.06.008","type":"journal-article","created":{"date-parts":[[2015,7,3]],"date-time":"2015-07-03T03:25:02Z","timestamp":1435893902000},"page":"784-791","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Fish oil\u2013supplemented parenteral nutrition could alleviate acute lung injury, modulate immunity, and reduce inflammation in rats with abdominal sepsis"],"prefix":"10.1016","volume":"35","author":[{"given":"Xiaolong","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianxiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enqin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nanyang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shougen","family":"Cao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanbing","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nutres.2015.06.008_bb0005","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.1001\/jama.2011.1831","article-title":"Immunosuppression in sepsis","volume":"306","author":"Ward","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.nutres.2015.06.008_bb0010","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1038\/nri3552","article-title":"Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy","volume":"13","author":"Hotchkiss","year":"2013","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.nutres.2015.06.008_bb0015","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.cellimm.2014.02.002","article-title":"Tremella polysaccharides attenuated sepsis through inhibiting abnormal CD4(+)CD25(high) regulatory T cells in mice","volume":"288","author":"Shi","year":"2014","journal-title":"Cell Immunol"},{"key":"10.1016\/j.nutres.2015.06.008_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s00423-013-1129-7","article-title":"Immunopathogenesis of abdominal sepsis","volume":"399","author":"Weber","year":"2014","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.nutres.2015.06.008_bb0025","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/j.1753-4887.2010.00287.x","article-title":"Fatty acids from fish: the anti-inflammatory potential of long-chain omega-3 fatty acids","volume":"68","author":"Wall","year":"2010","journal-title":"Nutr Rev"},{"key":"10.1016\/j.nutres.2015.06.008_bb0030","doi-asserted-by":"crossref","first-page":"964","DOI":"10.3945\/jn.110.132985","article-title":"Supplementation with a fish oil\u2013enriched, high-protein medical food leads to rapid incorporation of EPA into white blood cells and modulates immune responses within one week in healthy men and women","volume":"141","author":"Faber","year":"2011","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2015.06.008_bb0035","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1111\/j.1365-2362.2011.02582.x","article-title":"Short-term infusion of a fish oil\u2013based lipid emulsion modulates fatty acid status, but not immune function or (anti)oxidant balance: a randomized cross-over study","volume":"42","author":"Versleijen","year":"2012","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.nutres.2015.06.008_bb0040","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.nut.2008.01.012","article-title":"Effects of omega-3 fatty acids on inflammatory mediators and splenocyte cytokine mRNA expressions in rats with polymicrobial sepsis","volume":"24","author":"Tsou","year":"2008","journal-title":"Nutrition"},{"key":"10.1016\/j.nutres.2015.06.008_bb0045","article-title":"The effects of dexmedetomidine on secondary acute lung and kidney injuries in the rat model of intra-abdominal sepsis","volume":"292687","author":"Koca","year":"2013","journal-title":"ScientificWorldJournal"},{"key":"10.1016\/j.nutres.2015.06.008_bb0050","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1097\/SHK.0b013e31821e4f8b","article-title":"Fish oil\u2013supplemented parenteral nutrition prolongs survival while beneficially altering phospholipids' fatty acid composition and modulating immune function in rat sepsis","volume":"36","author":"Cao","year":"2011","journal-title":"Shock"},{"key":"10.1016\/j.nutres.2015.06.008_bb0055","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/S0899-9007(00)00512-8","article-title":"Parenteral supplementation with a fish-oil emulsion prolongs survival and improves rat lymphocyte function during sepsis","volume":"17","author":"Lanza-Jacoby","year":"2001","journal-title":"Nutrition"},{"key":"10.1016\/j.nutres.2015.06.008_bb0060","doi-asserted-by":"crossref","first-page":"e44987","DOI":"10.1371\/journal.pone.0044987","article-title":"Sepsis-induced acute lung injury (ALI) is milder in diabetic rats and correlates with impaired NFkB activation","volume":"7","author":"Jr Filgueiras","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2015.06.008_bb0065","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1097\/SHK.0b013e3181ac4b3b","article-title":"Induction of lymphocyte apoptosis in a murine model of acute lung injury\u2014modulation by lipid emulsions","volume":"33","author":"Bi","year":"2010","journal-title":"Shock"},{"key":"10.1016\/j.nutres.2015.06.008_bb0070","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.jss.2013.10.009","article-title":"Fish-oil emulsion (omega-3 polyunsaturated fatty acids) attenuates acute lung injury induced by intestinal ischemia-reperfusion through adenosine 5'-monophosphate\u2013activated protein kinase-sirtuin1 pathway","volume":"187","author":"Jing","year":"2014","journal-title":"J Surg Res"},{"key":"10.1016\/j.nutres.2015.06.008_bb0075","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1097\/00003246-200009000-00016","article-title":"Rapid onset of intestinal epithelial and lymphocyte apoptotic cell death in patients with trauma and shock","volume":"28","author":"Hotchkiss","year":"2000","journal-title":"Crit Care Med"},{"key":"10.1016\/j.nutres.2015.06.008_bb0080","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.nut.2006.11.005","article-title":"Effects of omega-3 fatty acids on leukocyte Th1\/Th2 cytokine and integrin expression in rats with gut-derived sepsis","volume":"23","author":"Lin","year":"2007","journal-title":"Nutrition"},{"key":"10.1016\/j.nutres.2015.06.008_bb0085","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1097\/ALN.0b013e31823422e8","article-title":"Advances in the management of sepsis and the understanding of key immunologic defects","volume":"115","author":"Skrupky","year":"2011","journal-title":"Anesthesiology"},{"key":"10.1016\/j.nutres.2015.06.008_bb0090","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1097\/CCM.0b013e318274645f","article-title":"Reduction of immunocompetent T cells followed by prolonged lymphopenia in severe sepsis in the elderly","volume":"41","author":"Inoue","year":"2013","journal-title":"Crit Care Med"},{"key":"10.1016\/j.nutres.2015.06.008_bb0095","doi-asserted-by":"crossref","first-page":"2594","DOI":"10.1001\/jama.2011.1829","article-title":"Immunosuppression in patients who die of sepsis and multiple organ failure","volume":"306","author":"Boomer","year":"2011","journal-title":"JAMA"},{"key":"10.1016\/j.nutres.2015.06.008_bb0100","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1056\/NEJMra021333","article-title":"The pathophysiology and treatment of sepsis","volume":"328","author":"Hotchkiss","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nutres.2015.06.008_bb0105","first-page":"450","article-title":"Altered T-lymphocyte subsets in severe sepsis","volume":"54","author":"Dahn","year":"1988","journal-title":"Am Surg"},{"key":"10.1016\/j.nutres.2015.06.008_bb0110","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/0002-9343(83)90412-6","article-title":"Alterations in lymphocyte cell surface markers during various human infections","volume":"75","author":"Jr Williams","year":"1983","journal-title":"Am J Med"},{"key":"10.1016\/j.nutres.2015.06.008_bb0115","doi-asserted-by":"crossref","first-page":"7943","DOI":"10.4049\/jimmunol.177.11.7943","article-title":"Increased natural CD4+CD25+ regulatory T cells and their suppressor activity do not contribute to mortality in murine polymicrobial sepsis","volume":"177","author":"Scumpia","year":"2006","journal-title":"J Immunol"},{"key":"10.1016\/j.nutres.2015.06.008_bb0120","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1189\/jlb.0607371","article-title":"Regulatory T cell populations in sepsis and trauma","volume":"83","author":"Venet","year":"2008","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.nutres.2015.06.008_bb0125","doi-asserted-by":"crossref","first-page":"2329","DOI":"10.1097\/01.CCM.0000145999.42971.4B","article-title":"Increased percentage of CD4+CD25+ regulatory T cells during septic shock is due to the decrease of CD4+CD25\u2212 lymphocytes","volume":"32","author":"Venet","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1016\/j.nutres.2015.06.008_bb0130","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1097\/CCM.0b013e3181e78ad0","article-title":"Role of regulatory T cells in long-term immune dysfunction associated with severe sepsis","volume":"38","author":"Nascimento","year":"2010","journal-title":"Crit Care Med"},{"key":"10.1016\/j.nutres.2015.06.008_bb0135","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1097\/01.shk.0000239780.33398.e4","article-title":"The contribution of CD4+ CD25+ T-regulatory-cells to immune suppression in sepsis","volume":"27","author":"Wisnoski","year":"2007","journal-title":"Shock"},{"key":"10.1016\/j.nutres.2015.06.008_bb0140","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1194\/jlr.M500033-JLR200","article-title":"Docosahexaenoic acid changes lipid composition and interleukin-2 receptor signaling in membrane rafts","volume":"46","author":"Li","year":"2005","journal-title":"J Lipid Res"},{"key":"10.1016\/j.nutres.2015.06.008_bb0145","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1194\/jlr.M900101-JLR200","article-title":"Docosahexaenoic acid reduces suppressive and migratory functions of CD4+CD25+ regulatory T-cells","volume":"50","author":"Yessoufou","year":"2009","journal-title":"J Lipid Res"},{"key":"10.1016\/j.nutres.2015.06.008_bb0150","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1017\/BJN20061891","article-title":"Dietary fish oil enhances adhesion molecule and interleukin-6 expression in mice with polymicrobial sepsis","volume":"96","author":"Hsu","year":"2006","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nutres.2015.06.008_bb0155","article-title":"A randomized controlled trial investigating the effects of parenteral fish oil on survival outcomes in critically ill patients with sepsis: a pilot study","author":"Hall","year":"2014","journal-title":"JPEN J Parenter Enteral Nutr"}],"container-title":["Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531715001578?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531715001578?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,16]],"date-time":"2022-05-16T21:21:11Z","timestamp":1652736071000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0271531715001578"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9]]},"references-count":31,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["S0271531715001578"],"URL":"https:\/\/doi.org\/10.1016\/j.nutres.2015.06.008","relation":{},"ISSN":["0271-5317"],"issn-type":[{"value":"0271-5317","type":"print"}],"subject":[],"published":{"date-parts":[[2015,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fish oil\u2013supplemented parenteral nutrition could alleviate acute lung injury, modulate immunity, and reduce inflammation in rats with abdominal sepsis","name":"articletitle","label":"Article Title"},{"value":"Nutrition Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nutres.2015.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}