{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:29:21Z","timestamp":1760646561814},"reference-count":52,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"crossref","award":["25560047"],"award-info":[{"award-number":["25560047"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Migakazuba Researchers from Ochanomizu University"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","nrjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition Research"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.nutres.2016.11.006","type":"journal-article","created":{"date-parts":[[2016,11,17]],"date-time":"2016-11-17T21:30:40Z","timestamp":1479418240000},"page":"1379-1391","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Vitamin C impacts anxiety-like behavior and stress-induced anorexia relative to social environment in SMP30\/GNL knockout mice"],"prefix":"10.1016","volume":"36","author":[{"given":"Miwako","family":"Koizumi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshitaka","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayumi","family":"Isaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akihito","family":"Ishigami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emiko","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.nutres.2016.11.006_bb0005","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.jpsychires.2011.11.009","article-title":"Ascorbic acid treatment, similarly to fluoxetine, reverses depressive-like behavior and brain oxidative damage induced by chronic unpredictable stress","volume":"46","author":"Moretti","year":"2012","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.nutres.2016.11.006_bb0010","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1475-2891-12-31","article-title":"Efficacy of vitamin C as an adjunct to fluoxetine therapy in pediatric major depressive disorder: a randomized, double-blind, placebo-controlled pilot study","volume":"12","author":"Amr","year":"2013","journal-title":"Nutr J"},{"key":"10.1016\/j.nutres.2016.11.006_bb0015","doi-asserted-by":"crossref","first-page":"1847","DOI":"10.3945\/jn.111.142257","article-title":"Foods, fortificants, and supplements: where do Americans get their nutrients?","volume":"141","author":"Fulgoni","year":"2011","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2016.11.006_bb0020","series-title":"The Goverment of Japan National Health and Nutrition Survey\u2013Japan (NHNS-J)","author":"Ministry of Health Law","year":"2013"},{"key":"10.1016\/j.nutres.2016.11.006_bb0025","series-title":"The Goverment of Japan. Dietary reference intakes for Japanese (DRIs-J)","author":"Ministry of Health Law","year":"2015"},{"key":"10.1016\/j.nutres.2016.11.006_bb0030","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/cbf.2895","article-title":"Water-immersion restraint stress disrupts nonenzymatic antioxidant defense systems through rapid and continuous ascorbic acid depletion in the adrenal gland of rats","volume":"31","author":"Ohta","year":"2013","journal-title":"Cell Biochem Funct"},{"key":"10.1016\/j.nutres.2016.11.006_bb0035","first-page":"3091","article-title":"Cardiovascular diseases: oxidative damage and antioxidant protection","volume":"18","author":"Zhang","year":"2014","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1016\/j.nutres.2016.11.006_bb0040","doi-asserted-by":"crossref","first-page":"93","DOI":"10.3109\/19390211.2013.790332","article-title":"A short-term evaluation of the relationship between plasma ascorbic acid levels and periodontal disease in systemically healthy and type 2 diabetes mellitus subjects","volume":"10","author":"Gokhale","year":"2013","journal-title":"J Diet Suppl"},{"key":"10.1016\/j.nutres.2016.11.006_bb0045","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0031-9384(01)00459-0","article-title":"Gender differences in vulnerability to social stress: a Darwinian perspective","volume":"73","author":"Troisi","year":"2001","journal-title":"Physiol Behav"},{"issue":"Suppl. 2","key":"10.1016\/j.nutres.2016.11.006_bb0050","doi-asserted-by":"crossref","first-page":"S213","DOI":"10.2105\/AJPH.2013.301277","article-title":"Housing instability and mental distress among US veterans","volume":"103","author":"Bossarte","year":"2013","journal-title":"Am J Public Health"},{"key":"10.1016\/j.nutres.2016.11.006_bb0055","first-page":"7027","article-title":"Lasting adaptations in social behavior produced by social disruption and inhibition of adult neurogenesis","volume":"36","author":"Opendak","year":"2016"},{"key":"10.1016\/j.nutres.2016.11.006_bb0060","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/j.psyneuen.2007.02.011","article-title":"Persistent neuroendocrine and behavioral effects of a novel, etiologically relevant mouse paradigm for chronic social stress during adolescence","volume":"32","author":"Schmidt","year":"2007","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.nutres.2016.11.006_bb0065","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1080\/10253890802049343","article-title":"Chronic social stress during adolescence in mice alters fat distribution in late life: prevention by antidepressant treatment","volume":"12","author":"Schmidt","year":"2009","journal-title":"Stress"},{"key":"10.1016\/j.nutres.2016.11.006_bb0070","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.yhbeh.2010.01.010","article-title":"A novel chronic social stress paradigm in female mice","volume":"57","author":"Schmidt","year":"2010","journal-title":"Horm Behav"},{"key":"10.1016\/j.nutres.2016.11.006_bb0075","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/S0006-3223(00)01041-6","article-title":"Altered fear circuits in 5-HT(1A) receptor KO mice","volume":"48","author":"Gross","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.nutres.2016.11.006_bb0080","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1124\/jpet.106.109678","volume":"321","author":"David","year":"2007","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.nutres.2016.11.006_bb0085","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1038\/266730a0","article-title":"Depression: a new animal model sensitive to antidepressant treatments","volume":"266","author":"Porsolt","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.nutres.2016.11.006_bb0090","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/0014-2999(78)90118-8","article-title":"Behavioural despair in rats: a new model sensitive to antidepressant treatments","volume":"47","author":"Porsolt","year":"1978","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.nutres.2016.11.006_bb0095","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0166-4328(00)00220-5","article-title":"Influence of single or repeated experience of rats with forced swimming on behavioural and physiological responses to the stressor","volume":"114","author":"Dal-Zotto","year":"2000","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.nutres.2016.11.006_bb0100","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jneumeth.2010.12.015","article-title":"Repeated rat-forced swim test: reducing the number of animals to evaluate gradual effects of antidepressants","volume":"195","author":"Mezadri","year":"2011","journal-title":"J Neurosci Methods"},{"key":"10.1016\/j.nutres.2016.11.006_bb0105","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.pnpbp.2014.10.017","article-title":"Influence of enrichment on behavioral and neurogenic effects of antidepressants in Wistar rats submitted to repeated forced swim test","volume":"58","author":"Possamai","year":"2015","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.nutres.2016.11.006_bb0110","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.ejphar.2009.06.018","article-title":"Use of latency to immobility improves detection of antidepressant-like activity in the behavioral despair test in the mouse","volume":"616","author":"Castagne","year":"2009","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.nutres.2016.11.006_bb0115","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1007\/s10571-005-8468-z","article-title":"Enhanced BDNF signaling is associated with an antidepressant-like behavioral response and changes in brain monoamines","volume":"25","author":"Koponen","year":"2005","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.nutres.2016.11.006_bb0120","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1038\/nn.2647","article-title":"Animal models of neuropsychiatric disorders","volume":"13","author":"Nestler","year":"2010","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.nutres.2016.11.006_bb0125","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1079\/BJN19940076","article-title":"Ascorbic acid deficiency in guinea pigs: contrasting effects of tissue ascorbic acid depletion and of associated inanition on status indices related to collagen and vitamin D","volume":"72","author":"Tsuchiya","year":"1994","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nutres.2016.11.006_bb0130","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/S0002-9440(10)64404-5","article-title":"Senescence marker protein\u201330 knockout mouse liver is highly susceptible to tumor necrosis factor-alpha\u2013 and Fas-mediated apoptosis","volume":"161","author":"Ishigami","year":"2002","journal-title":"Am J Pathol"},{"key":"10.1016\/j.nutres.2016.11.006_bb0135","doi-asserted-by":"crossref","first-page":"5723","DOI":"10.1073\/pnas.0511225103","article-title":"Senescence marker protein 30 functions as gluconolactonase in l-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy","volume":"103","author":"Kondo","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.nutres.2016.11.006_bb0140","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.nut.2010.04.010","article-title":"Time course of vitamin C distribution and absorption after oral administration in SMP30\/GNL knockout mice","volume":"27","author":"Iwama","year":"2011","journal-title":"Nutrition"},{"key":"10.1016\/j.nutres.2016.11.006_bb0145","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.bbrc.2008.09.132","article-title":"Vitamin C depletion increases superoxide generation in brains of SMP30\/GNL knockout mice","volume":"377","author":"Kondo","year":"2008","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.nutres.2016.11.006_bb0150","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0006-3223(02)01827-9","article-title":"Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice","volume":"54","author":"Merali","year":"2003","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.nutres.2016.11.006_bb0155","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/0471142301.ns0810as55","article-title":"Rodent models of depression: forced swim and tail suspension behavioral despair tests in rats and mice","volume":"55","author":"Castagne","year":"2011","journal-title":"Curr Protoc Neurosci"},{"key":"10.1016\/j.nutres.2016.11.006_bb0160","doi-asserted-by":"crossref","first-page":"31","DOI":"10.2131\/jts.36.31","article-title":"Depression-related anhedonic behaviors caused by immobilization stress: a comparison with nicotine-induced depression-like behavioral alterations and effects of nicotine and\/or \"antidepressant\" drugs","volume":"36","author":"Hayase","year":"2011","journal-title":"J Toxicol Sci"},{"key":"10.1016\/j.nutres.2016.11.006_bb0165","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.bbrc.2004.01.091","article-title":"SMP30 deficiency in mice causes an accumulation of neutral lipids and phospholipids in the liver and shortens the life span","volume":"315","author":"Ishigami","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.nutres.2016.11.006_bb0170","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.2741\/4160","article-title":"Effects of vitamin C on health: a review of evidence","volume":"18","author":"Grosso","year":"2013","journal-title":"Front Biosci (Landmark Ed)"},{"key":"10.1016\/j.nutres.2016.11.006_bb0175","doi-asserted-by":"crossref","first-page":"9286","DOI":"10.1021\/jf502587j","article-title":"Potato chip intake increases ascorbic acid levels and decreases reactive oxygen species in SMP30\/GNL knockout mouse tissues","volume":"62","author":"Kondo","year":"2014","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.nutres.2016.11.006_bb0180","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/0031-9384(91)90212-7","article-title":"Taste preference and protein nutrition and L-amino acid homeostasis in male Sprague-Dawley rats","volume":"49","author":"Mori","year":"1991","journal-title":"Physiol Behav"},{"key":"10.1016\/j.nutres.2016.11.006_bb0185","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1007\/s00726-003-0358-4","article-title":"Metabolic interactions between restraint stress and l-lysine: the effect on urea cycle components","volume":"24","author":"Smriga","year":"2003","journal-title":"Amino Acids"},{"key":"10.1016\/j.nutres.2016.11.006_bb0190","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1523\/JNEUROSCI.5584-07.2008","article-title":"Orexin signaling mediates the antidepressant-like effect of calorie restriction","volume":"28","author":"Lutter","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.nutres.2016.11.006_bb0195","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/0031-9384(90)90361-7","article-title":"Plasma catecholamine, corticosterone and glucose responses to repeated stress in rats: effect of interstressor interval length","volume":"47","author":"De Boer","year":"1990","journal-title":"Physiol Behav"},{"key":"10.1016\/j.nutres.2016.11.006_bb0200","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.psychres.2012.04.032","article-title":"Depression, anxiety and obsessive-compulsive symptoms in relation to nutritional status and outcome in severe anorexia nervosa","volume":"200","author":"Mattar","year":"2012","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.nutres.2016.11.006_bb0205","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.jad.2010.09.014","article-title":"Relationship between malnutrition and depression or anxiety in anorexia nervosa: a critical review of the literature","volume":"132","author":"Mattar","year":"2011","journal-title":"J Affect Disord"},{"key":"10.1016\/j.nutres.2016.11.006_bb0210","first-page":"16362","article-title":"Sex differences in nucleus accumbens transcriptome profiles associated with susceptibility versus resilience to subchronic variable stress","volume":"35","author":"Hodes","year":"2015"},{"key":"10.1016\/j.nutres.2016.11.006_bb0215","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.neubiorev.2014.11.017","article-title":"Inoculation stress hypothesis of environmental enrichment","volume":"49","author":"Crofton","year":"2015","journal-title":"Neurosci Biobehav Rev"},{"issue":"Suppl. 1","key":"10.1016\/j.nutres.2016.11.006_bb0220","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.neurobiolaging.2005.08.020","article-title":"Protective environments and health status: cross-talk between human and animal studies","volume":"26","author":"Singer","year":"2005","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.nutres.2016.11.006_bb0225","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1196\/annals.1297.012","article-title":"Environmental enrichment-behavior-oxidative stress interactions in the aged rat: issues for a therapeutic approach in human aging","volume":"1019","author":"Fernandez","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.nutres.2016.11.006_bb0230","first-page":"77","article-title":"Metabolism and antioxidant function of glutathione","volume":"44","author":"Gerard-Monnier","year":"1996","journal-title":"Pathol Biol"},{"key":"10.1016\/j.nutres.2016.11.006_bb0235","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1002\/jcb.24092","article-title":"Oxidative stress markers and apoptosis in the prostate of diabetic rats and the influence of vitamin C treatment","volume":"113","author":"Gobbo","year":"2012","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.nutres.2016.11.006_bb0240","doi-asserted-by":"crossref","first-page":"929","DOI":"10.3945\/ajcn.111.011460","article-title":"Serum vitamin C and other biomarkers differ by genotype of phase 2 enzyme genes GSTM1 and GSTT1","volume":"94","author":"Block","year":"2011","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nutres.2016.11.006_bb0245","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/j.pnpbp.2012.07.013","article-title":"Reduced antioxidant defense systems in schizophrenia and bipolar I disorder","volume":"39","author":"Raffa","year":"2012","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"key":"10.1016\/j.nutres.2016.11.006_bb0250","doi-asserted-by":"crossref","first-page":"e1944","DOI":"10.1371\/journal.pone.0001944","article-title":"Negative correlation between brain glutathione level and negative symptoms in schizophrenia: a 3 T 1H-MRS study","volume":"3","author":"Matsuzawa","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2016.11.006_bb0255","first-page":"Cc04","article-title":"Oxidative stress and major depression","volume":"8","author":"Bajpai","year":"2014","journal-title":"J Clin Diagn Res"},{"key":"10.1016\/j.nutres.2016.11.006_bb0260","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1179\/135100003225003393","article-title":"Oxidative damage and major depression: the potential antioxidant action of selective serotonin re-uptake inhibitors","volume":"8","author":"Khanzode","year":"2003","journal-title":"Redox Rep"}],"container-title":["Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531716306728?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531716306728?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T10:51:37Z","timestamp":1601203897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0271531716306728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":52,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0271531716306728"],"URL":"https:\/\/doi.org\/10.1016\/j.nutres.2016.11.006","relation":{},"ISSN":["0271-5317"],"issn-type":[{"value":"0271-5317","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Vitamin C impacts anxiety-like behavior and stress-induced anorexia relative to social environment in SMP30\/GNL knockout mice","name":"articletitle","label":"Article Title"},{"value":"Nutrition Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nutres.2016.11.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}