{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T04:22:55Z","timestamp":1787286175671,"version":"build-2736575974"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition Research"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.nutres.2017.08.002","type":"journal-article","created":{"date-parts":[[2017,8,26]],"date-time":"2017-08-26T02:31:05Z","timestamp":1503714665000},"page":"68-77","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":27,"special_numbering":"C","title":["Protein blend ingestion before allogeneic stem cell transplantation improves protein-energy malnutrition in patients with leukemia"],"prefix":"10.1016","volume":"46","author":[{"given":"Guangxu","family":"Ren","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghua","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suqin","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongru","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nutres.2017.08.002_bb0005","doi-asserted-by":"crossref","first-page":"83","DOI":"10.3322\/caac.21219","article-title":"Childhood and adolescent cancer statistics, 2014","volume":"64","author":"Ward","year":"2014","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.nutres.2017.08.002_bb0010","doi-asserted-by":"crossref","first-page":"146","DOI":"10.5539\/gjhs.v8n7p146","article-title":"Leukemia-related mortality in Inner Mongolia, 2008-2012","volume":"8","author":"Hao","year":"2015","journal-title":"Glob J Health Sci"},{"key":"10.1016\/j.nutres.2017.08.002_bb0015","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1002\/(SICI)1097-0215(1998)78:11+<81::AID-IJC23>3.0.CO;2-0","article-title":"Growth and body composition in response to chemotherapy in children with acute lymphoblastic leukemia","volume":"11","author":"Halton","year":"1998","journal-title":"Int J Cancer Suppl"},{"key":"10.1016\/j.nutres.2017.08.002_bb0020","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1177\/0148607190014003315","article-title":"Special nutritional needs of children with malignancies: a review","volume":"14","author":"Mauer","year":"1990","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0025","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1146\/annurev.nu.05.070185.002251","article-title":"Nutrition and cancer: physiological interrelationships","volume":"5","author":"van Eys","year":"1985","journal-title":"Annu Rev Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0030","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1093\/ajcn\/65.1.95","article-title":"Nutritional status of children with acute lymphoblastic leukemia: a longitudinal study","volume":"65","author":"Delbecque-Boussard","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0035","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1002\/1097-0142(19850101)55:1+<238::AID-CNCR2820551306>3.0.CO;2-S","article-title":"Tissue components of weight loss in cancer patients. A new method of study and preliminary observations","volume":"55","author":"Heymsfield","year":"1985","journal-title":"Cancer"},{"key":"10.1016\/j.nutres.2017.08.002_bb0040","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1002\/1097-0142(19900715)66:2<373::AID-CNCR2820660229>3.0.CO;2-C","article-title":"Skeletal muscle wasting and protein-energy malnutrition in children with a newly diagnosed acute leukemia","volume":"66","author":"Koskelo","year":"1990","journal-title":"Cancer"},{"key":"10.1016\/j.nutres.2017.08.002_bb0045","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1136\/bmj.293.6553.983","article-title":"Effects of nutrient intake, surgery, sepsis, and long term administration of steroids on muscle function","volume":"293","author":"Brough","year":"1986","journal-title":"Br Med J (Clin Res Ed)"},{"key":"10.1016\/j.nutres.2017.08.002_bb0050","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S1470-2045(08)70153-0","article-title":"Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study","volume":"9","author":"Prado","year":"2008","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0055","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1016\/0145-2126(89)90043-X","article-title":"Leukaemia and nutrition. I: malnutrition is an adverse prognostic factor in the outcome of treatment of patients with standard-risk acute lymphoblastic leukaemia","volume":"13","author":"Lobato-Mendizabal","year":"1989","journal-title":"Leuk Res"},{"key":"10.1016\/j.nutres.2017.08.002_bb0060","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1097\/MCO.0b013e32831cef75","article-title":"Maximizing muscle protein anabolism: the role of protein quality","volume":"12","author":"Tang","year":"2009","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.nutres.2017.08.002_bb0065","doi-asserted-by":"crossref","first-page":"464S","DOI":"10.1080\/07315724.2009.10718113","article-title":"The rationale for consuming protein blends in sports nutrition","volume":"28 Suppl","author":"Paul","year":"2009","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0070","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1039\/C6FO01692H","article-title":"Ingestion of soy-whey blended protein augments sports performance and ameliorates exercise-induced fatigue in a rat exercise model","volume":"8","author":"Ren","year":"2017","journal-title":"Food Funct"},{"key":"10.1016\/j.nutres.2017.08.002_bb0075","doi-asserted-by":"crossref","first-page":"14930","DOI":"10.1073\/pnas.94.26.14930","article-title":"Slow and fast dietary proteins differently modulate postprandial protein accretion","volume":"94","author":"Boirie","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.nutres.2017.08.002_bb0080","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1152\/japplphysiol.01093.2013","article-title":"Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle","volume":"116","author":"Reidy","year":"2014","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0085","doi-asserted-by":"crossref","first-page":"410","DOI":"10.3945\/jn.112.168021","article-title":"Protein blend ingestion following resistance exercise promotes human muscle protein synthesis","volume":"143","author":"Reidy","year":"2013","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0090","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/ecc.12262","article-title":"The effect of dietary intake changes on nutritional status in acute leukaemia patients after first induction chemotherapy","volume":"24","author":"Malihi","year":"2015","journal-title":"Eur J Cancer Care (Engl)"},{"key":"10.1016\/j.nutres.2017.08.002_bb0095","doi-asserted-by":"crossref","first-page":"3385","DOI":"10.1007\/s00520-015-2850-2","article-title":"Pre-transplant arm muscle area: a simple measure to identify patients at risk","volume":"23","author":"Thomaz","year":"2015","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.nutres.2017.08.002_bb0100","doi-asserted-by":"crossref","first-page":"2036","DOI":"10.1002\/1097-0142(197905)43:5+<2036::AID-CNCR2820430712>3.0.CO;2-7","article-title":"Alterations of nutritional status: impact of chemotherapy and radiation therapy","volume":"43","author":"Donaldson","year":"1979","journal-title":"Cancer"},{"key":"10.1016\/j.nutres.2017.08.002_bb0105","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1200\/JCO.2012.45.2722","article-title":"Cancer cachexia in the age of obesity: skeletal muscle depletion is a powerful prognostic factor, independent of body mass index","volume":"31","author":"Martin","year":"2013","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0110","doi-asserted-by":"crossref","first-page":"654","DOI":"10.4065\/77.7.654","article-title":"Audit of nutrition support for hematopoietic stem cell transplantation at a single institution","volume":"77","author":"Scolapio","year":"2002","journal-title":"Mayo Clin Proc"},{"key":"10.1016\/j.nutres.2017.08.002_bb0115","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1177\/0148607190014005480","article-title":"Protein metabolism assessed by 1-13C leucine infusions in patients undergoing bone marrow transplantation","volume":"14","author":"Keller","year":"1990","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0120","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1177\/0148607185009002139","article-title":"Energy requirements of parenterally fed bone marrow transplant recipients","volume":"9","author":"Szeluga","year":"1985","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0125","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1177\/0148607191015002184","article-title":"Parenteral nutrition for marrow transplant recipients: evaluation of an increased nitrogen dose","volume":"15","author":"Geibig","year":"1991","journal-title":"JPEN J Parenter Enteral Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0130","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.1056\/NEJMoa021423","article-title":"Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults","volume":"348","author":"Calle","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nutres.2017.08.002_bb0135","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1016\/S0899-9007(00)00407-X","article-title":"Regulation of skeletal-muscle-protein turnover in cancer-associated cachexia","volume":"16","author":"Baracos","year":"2000","journal-title":"Nutrition"},{"key":"10.1016\/j.nutres.2017.08.002_bb0140","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/S0016-5085(83)80074-2","article-title":"Graft-versus-host disease of the intestine: a protein losing enteropathy characterized by fecal alpha 1-antitrypsin","volume":"85","author":"Weisdorf","year":"1983","journal-title":"Gastroenterology"},{"key":"10.1016\/j.nutres.2017.08.002_bb0145","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1007\/s00277-013-1957-0","article-title":"Serum albumin level predicts survival of patients with gastrointestinal acute graft-versus-host disease after allogeneic stem cell transplantation","volume":"93","author":"Ayuk","year":"2014","journal-title":"Ann Hematol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0150","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1016\/j.bbmt.2011.07.021","article-title":"Decreased serum albumin as a biomarker for severe acute graft-versus-host disease after reduced-intensity allogeneic hematopoietic cell transplantation","volume":"17","author":"Rezvani","year":"2011","journal-title":"Biol Blood Marrow Transplant"},{"key":"10.1016\/j.nutres.2017.08.002_bb0155","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1249\/01.MSS.0000147582.99810.C5","article-title":"Ingestion of casein and whey proteins result in muscle anabolism after resistance exercise","volume":"36","author":"Tipton","year":"2004","journal-title":"Med Sci Sports Exerc"},{"key":"10.1016\/j.nutres.2017.08.002_bb0160","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1152\/japplphysiol.00076.2009","article-title":"Ingestion of whey hydrolysate, casein, or soy protein isolate: effects on mixed muscle protein synthesis at rest and following resistance exercise in young men","volume":"107","author":"Tang","year":"2009","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0165","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1186\/1475-2891-3-22","article-title":"Soy versus whey protein bars: effects on exercise training impact on lean body mass and antioxidant status","volume":"3","author":"Brown","year":"2004","journal-title":"Nutr J"},{"key":"10.1016\/j.nutres.2017.08.002_bb0170","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1080\/10408399509527692","article-title":"Antioxidants and physical performance","volume":"35","author":"Clarkson","year":"1995","journal-title":"Crit Rev Food Sci Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0175","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1093\/jn\/130.10.2413","article-title":"Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway","volume":"130","author":"Anthony","year":"2000","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0180","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1093\/jn\/135.3.376","article-title":"Oral leucine administration stimulates protein synthesis in rat skeletal muscle","volume":"135","author":"Crozier","year":"2005","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0185","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/00075197-200001000-00007","article-title":"The effect of age on protein metabolism","volume":"3","author":"Short","year":"2000","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.nutres.2017.08.002_bb0190","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1093\/ajcn\/66.4.774","article-title":"Aging, protein requirements, and protein turnover","volume":"66","author":"Millward","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0195","first-page":"107","article-title":"Muscle protein turnover: methodological issues and the effect of aging","volume":"50 Spec No","author":"Nair","year":"1995","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.nutres.2017.08.002_bb0200","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1093\/ajcn\/66.4.880","article-title":"Whole-body protein turnover in the healthy elderly","volume":"66","author":"Morais","year":"1997","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0205","doi-asserted-by":"crossref","first-page":"2186","DOI":"10.1016\/j.biocel.2013.06.021","article-title":"Muscle wasting: the gut microbiota as a new therapeutic target?","volume":"45","author":"Bindels","year":"2013","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0210","doi-asserted-by":"crossref","first-page":"e37971","DOI":"10.1371\/journal.pone.0037971","article-title":"Restoring specific lactobacilli levels decreases inflammation and muscle atrophy markers in an acute leukemia mouse model","volume":"7","author":"Bindels","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2017.08.002_bb0215","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3945\/jn.115.224196","article-title":"Soy protein compared with milk protein in a western diet increases gut microbial diversity and reduces serum lipids in golden Syrian hamsters","volume":"146","author":"Butteiger","year":"2016","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2017.08.002_bb0220","doi-asserted-by":"crossref","first-page":"e88904","DOI":"10.1371\/journal.pone.0088904","article-title":"Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and the gut microbiota in C57BL\/6J mice","volume":"9","author":"McAllan","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2017.08.002_bb0225","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/S0301-472X(00)00169-7","article-title":"Transplantation with selected autologous peripheral blood cd34+thy1+ hematopoietic stem cells (hscs) in multiple myeloma: impact of hsc dose on engraftment, safety, and immune reconstitution","volume":"28","author":"Michallet","year":"2000","journal-title":"Exp Hematol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0230","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.transci.2006.08.009","article-title":"Factors influencing engraftment in autologous peripheral hematopoetic stem cell transplantation (PBSCT)","volume":"36","author":"Ergene","year":"2007","journal-title":"Transfus Apher Sci"},{"key":"10.1016\/j.nutres.2017.08.002_bb0235","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1093\/oxfordjournals.annonc.a010721","article-title":"Multivariate analyses of prognostic factors associated with hematopoietic recovery in autograft patients with different sources of progenitor cells. A GATMO experience. Argintine Group of Bone Marrow Transplant","volume":"7","author":"Pavlovsky","year":"1996","journal-title":"Ann Oncol"},{"key":"10.1016\/j.nutres.2017.08.002_bb0240","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1056\/NEJM198901263200401","article-title":"Effect of HLA compatibility on engraftment of bone marrow transplants in patients with leukemia or lymphoma","volume":"320","author":"Anasetti","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1016\/j.nutres.2017.08.002_bb0245","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1378\/chest.109.4.1066","article-title":"Pulmonary complications of bone marrow transplantation","volume":"109","author":"Soubani","year":"1996","journal-title":"Chest"},{"key":"10.1016\/j.nutres.2017.08.002_bb0250","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1182\/blood.V75.9.1888.1888","article-title":"Cytomegalovirus infection after autologous bone marrow transplantation: occurrence of cytomegalovirus disease and effect on engraftment","volume":"75","author":"Reusser","year":"1990","journal-title":"Blood"},{"key":"10.1016\/j.nutres.2017.08.002_bb0255","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1200\/JCO.1995.13.6.1323","article-title":"Granulocyte colony-stimulating factor accelerates neutrophil engraftment following peripheral-blood stem-cell transplantation: a prospective, randomized trial","volume":"13","author":"Klumpp","year":"1995","journal-title":"J Clin Oncol"}],"container-title":["Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531717304888?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531717304888?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,10,16]],"date-time":"2020-10-16T10:03:42Z","timestamp":1602842622000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0271531717304888"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":51,"alternative-id":["S0271531717304888"],"URL":"https:\/\/doi.org\/10.1016\/j.nutres.2017.08.002","relation":{},"ISSN":["0271-5317"],"issn-type":[{"value":"0271-5317","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protein blend ingestion before allogeneic stem cell transplantation improves protein-energy malnutrition in patients with leukemia","name":"articletitle","label":"Article Title"},{"value":"Nutrition Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nutres.2017.08.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}