{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T19:38:50Z","timestamp":1784230730916,"version":"3.55.0"},"reference-count":68,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:00:00Z","timestamp":1569888000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition Research"],"published-print":{"date-parts":[[2019,10]]},"DOI":"10.1016\/j.nutres.2018.06.004","type":"journal-article","created":{"date-parts":[[2018,6,27]],"date-time":"2018-06-27T22:32:36Z","timestamp":1530138756000},"page":"50-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Depletion of regulator-of-G-protein signaling-10 in mice exaggerates high-fat diet-induced insulin resistance and inflammation, and this effect is mitigated by dietary green tea extract"],"prefix":"10.1016","volume":"70","author":[{"given":"Xi","family":"Fang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaegwon","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Olsen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Snider","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachael H.","family":"Earls","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Jeon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hea Jin","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Kyung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Supplement 1","key":"10.1016\/j.nutres.2018.06.004_bb0005","doi-asserted-by":"crossref","first-page":"S439","DOI":"10.1016\/j.dsx.2017.03.032","article-title":"Risk of diabetes according to the metabolic health status and degree of obesity","volume":"11","author":"Janghorbani","year":"2017","journal-title":"Diabetes Metab Syndr"},{"issue":"1","key":"10.1016\/j.nutres.2018.06.004_bb0010","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.pcad.2017.05.005","article-title":"The interaction of cardiorespiratory fitness with obesity and the obesity paradox in cardiovascular disease","volume":"60","author":"Oktay","year":"2017","journal-title":"Prog Cardiovasc Dis"},{"key":"10.1016\/j.nutres.2018.06.004_bb0015","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0092-8674(00)80998-8","article-title":"EGL-10 regulates G protein signaling in the C elegans nervous system and shares a conserved domain with many mammalian proteins","volume":"84","author":"Koelle","year":"1996","journal-title":"Cell"},{"key":"10.1016\/j.nutres.2018.06.004_bb0020","doi-asserted-by":"crossref","first-page":"7216","DOI":"10.1073\/pnas.94.14.7216","article-title":"The regulators of G protein signaling (RGS) domains of RGS4, RGS10, and GAIP retain GTPase activating protein activity in vitro","volume":"94","author":"Popov","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.nutres.2018.06.004_bb0025","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1146\/annurev.biochem.69.1.795","article-title":"GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins","volume":"69","author":"Ross","year":"2000","journal-title":"Annu Rev Biochem"},{"key":"10.1016\/j.nutres.2018.06.004_bb0030","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1006\/geno.2002.6693","article-title":"Evolution of the regulators of G-protein signaling multigene family in mouse and human","volume":"79","author":"Sierra","year":"2002","journal-title":"Genomics"},{"key":"10.1016\/j.nutres.2018.06.004_bb0035","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0027984","article-title":"Association between regulator of G protein signaling 9-2 and body weight","volume":"6","author":"Waugh","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2018.06.004_bb0040","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/j.physbeh.2014.10.012","article-title":"Effects of gender on locomotor sensitivity to amphetamine, body weight, and fat mass in regulator of G protein signaling 9 (RGS9) knockout mice","volume":"138","author":"Walker","year":"2015","journal-title":"Physiol Behav"},{"key":"10.1016\/j.nutres.2018.06.004_bb0045","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1038\/oby.2010.333","article-title":"RGS6 variants are associated with dietary fat intake in Hispanics: the IRAS Family Study","volume":"19","author":"Sibbel","year":"2011","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.nutres.2018.06.004_bb0050","article-title":"Loss of regulator of G protein signaling 5 exacerbates obesity, hepatic steatosis, inflammation and insulin resistance","volume":"7","author":"Deng","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2018.06.004_bb0055","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.metabol.2007.10.021","article-title":"RGS2 C1114G polymorphism and body weight gain in hypertensive patients","volume":"57","author":"Sartori","year":"2008","journal-title":"Metabolism"},{"key":"10.1016\/j.nutres.2018.06.004_bb0060","doi-asserted-by":"crossref","first-page":"4470","DOI":"10.1210\/endo.139.11.6282","article-title":"Role of regulator of G protein signaling in desensitization of the glucose-dependent insulinotropic peptide receptor","volume":"139","author":"Tseng","year":"1998","journal-title":"Endocrinology"},{"key":"10.1016\/j.nutres.2018.06.004_bb0065","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.4049\/jimmunol.171.3.1542","article-title":"Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation","volume":"171","author":"Lippert","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.nutres.2018.06.004_bb0070","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.molmet.2016.08.010","article-title":"The regulator of G-protein signaling RGS16 promotes insulin secretion and beta-cell proliferation in rodent and human islets","volume":"5","author":"Vivot","year":"2016","journal-title":"Mol Metab"},{"key":"10.1016\/j.nutres.2018.06.004_bb0075","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/383175a0","article-title":"RGS10 is a selective activator of G alpha i GTPase activity","volume":"383","author":"Hunt","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.nutres.2018.06.004_bb0080","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0378-1119(02)00883-1","article-title":"Structure, chromosomal localization and expression of the mouse regulator of G-protein signaling10 gene (mRGS10)","volume":"297","author":"Haller","year":"2002","journal-title":"Gene"},{"key":"10.1016\/j.nutres.2018.06.004_bb0085","doi-asserted-by":"crossref","first-page":"8517","DOI":"10.1523\/JNEUROSCI.1806-08.2008","article-title":"Regulator of G-protein signaling 10 promotes dopaminergic neuron survival via regulation of the microglial inflammatory response","volume":"28","author":"Lee","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.nutres.2018.06.004_bb0090","doi-asserted-by":"crossref","first-page":"11879","DOI":"10.1523\/JNEUROSCI.1002-11.2011","article-title":"Regulator of G-protein signaling-10 negatively regulates NF-kappaB in microglia and neuroprotects dopaminergic neurons in hemiparkinsonian rats","volume":"31","author":"Lee","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.nutres.2018.06.004_bb0095","article-title":"Critical role of regulator G-protein signaling 10 (RGS10) in modulating macrophage M1\/M2 activation","volume":"8","author":"Lee","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2018.06.004_bb0100","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s12906-016-1077-1","article-title":"Beneficial effects of cocoa, coffee, green tea, and garcinia complex supplement on diet induced obesity in rats","volume":"16","author":"Huang","year":"2016","journal-title":"BMC Complement Altern Med"},{"key":"10.1016\/j.nutres.2018.06.004_bb0105","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.3390\/molecules21101305","article-title":"Beneficial Effects of Tea and the Green Tea Catechin Epigallocatechin-3-gallate on Obesity","volume":"21","author":"Suzuki","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.nutres.2018.06.004_bb0110","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.ijcard.2016.07.142","article-title":"Green tea consumption and risk of cardiovascular disease or stroke","volume":"221","author":"Kawada","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.nutres.2018.06.004_bb0115","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s10654-016-0173-3","article-title":"Association of green tea consumption with mortality from all-cause, cardiovascular disease and cancer in a Chinese cohort of 165,000 adult men","volume":"31","author":"Liu","year":"2016","journal-title":"Eur J Epidemiol"},{"key":"10.1016\/j.nutres.2018.06.004_bb0120","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.biopha.2016.12.082","article-title":"Green tea epigallocatechin 3-gallate alleviates hyperglycemia and reduces advanced glycation end products via nrf2 pathway in mice with high fat diet-induced obesity","volume":"87","author":"Sampath","year":"2017","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.nutres.2018.06.004_bb0125","first-page":"545","article-title":"Effect modification of green tea on the association between rice intake and the risk of diabetes mellitus: a prospective study in Japanese men and women","volume":"26","author":"Hirata","year":"2017","journal-title":"Asia Pac J Clin Nutr"},{"issue":"4","key":"10.1016\/j.nutres.2018.06.004_bb0130","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/cts.12470","article-title":"Bioinformatics analysis on molecular mechanism of green tea compound epigallocatechin-3-gallate against ovarian cancer","volume":"10","author":"Xinqiang","year":"2017","journal-title":"Clin Transl Sci"},{"key":"10.1016\/j.nutres.2018.06.004_bb0135","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/1691568","article-title":"Protective effect of green tea (Camellia sinensis (L.) Kuntze) against prostate cancer: from in vitro data to Algerian patients","volume":"2017","author":"Lassed","year":"2017","journal-title":"Evid Based Complement Alternat Med"},{"key":"10.1016\/j.nutres.2018.06.004_bb0140","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.3945\/jn.114.191007","article-title":"Green tea, black tea, and oolong tea polyphenols reduce visceral fat and inflammation in mice fed high-fat, high-sucrose obesogenic diets","volume":"144","author":"Heber","year":"2014","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2018.06.004_bb0145","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/635470","article-title":"Green tea extract supplementation induces the lipolytic pathway, attenuates obesity, and reduces low-grade inflammation in mice fed a high-fat diet","volume":"2013","author":"Cunha","year":"2013","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.nutres.2018.06.004_bb0150","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/j.jnutbio.2018.03.024","article-title":"Polyphenol-rich green tea extract improves adipose tissue metabolism by down-regulating miR-335 expression and mitigating insulin resistance and inflammation","volume":"57","author":"Otton","year":"2018","journal-title":"J Nutr Biochem"},{"key":"10.1016\/j.nutres.2018.06.004_bb0155","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1089\/jmf.2014.3265","article-title":"Fermented green tea extract alleviates obesity and related complications and alters gut microbiota composition in diet-induced obese mice","volume":"18","author":"Seo","year":"2015","journal-title":"J Med Food"},{"key":"10.1016\/j.nutres.2018.06.004_bb0160","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ejphar.2008.10.044","article-title":"PCR differential display-based identification of regulator of G protein signaling 10 as the target gene in human colon cancer cells induced by black tea polyphenol theaflavin monogallate","volume":"601","author":"Lu","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.nutres.2018.06.004_bb0165","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.bbadis.2013.05.017","article-title":"Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance","volume":"1842","author":"Lee","year":"2014","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.nutres.2018.06.004_bb0170","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1038\/33423","article-title":"Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells","volume":"392","author":"Zambrowicz","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.nutres.2018.06.004_bb0175","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1089\/jmf.2014.0048","article-title":"Green tea lowers hepatic COX-2 and prostaglandin E2 in rats with dietary fat-induced nonalcoholic steatohepatitis","volume":"18","author":"Chung","year":"2015","journal-title":"J Med Food"},{"key":"10.1016\/j.nutres.2018.06.004_bb0180","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3945\/jn.111.148544","article-title":"Green tea extract suppresses NFkappaB activation and inflammatory responses in diet-induced obese rats with nonalcoholic steatohepatitis","volume":"142","author":"Park","year":"2012","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2018.06.004_bb0185","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1002\/oby.20330","article-title":"7765 improves metabolic and immunological alterations associated with obesity in high-fat diet-fed mice","volume":"21","author":"Cano","year":"2013","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.nutres.2018.06.004_bb0190","doi-asserted-by":"crossref","first-page":"978","DOI":"10.2337\/diabetes.55.04.06.db05-1339","article-title":"Gonadal hormones determine sensitivity to central leptin and insulin","volume":"55","author":"Clegg","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.nutres.2018.06.004_bb0195","doi-asserted-by":"crossref","first-page":"E1323","DOI":"10.1152\/ajpendo.90617.2008","article-title":"Evaluating the glucose tolerance test in mice","volume":"295","author":"Andrikopoulos","year":"2008","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.nutres.2018.06.004_bb0200","doi-asserted-by":"crossref","first-page":"212","DOI":"10.3164\/jcbn.09-83","article-title":"A mouse model of metabolic syndrome: insulin resistance, fatty liver and non-alcoholic fatty pancreas disease (NAFPD) in C57BL\/6 mice fed a high fat diet","volume":"46","author":"Fraulob","year":"2010","journal-title":"J Clin Biochem Nutr"},{"key":"10.1016\/j.nutres.2018.06.004_bb0205","series-title":"Design and analysis: A researcher's handbook","author":"Keppel","year":"2004"},{"key":"10.1016\/j.nutres.2018.06.004_bb0210","doi-asserted-by":"crossref","first-page":"124","DOI":"10.2174\/1573399810666140421124051","article-title":"Glycaemic control: a balancing act or a different approach?","volume":"10","author":"Fava","year":"2014","journal-title":"Curr Diabetes Rev"},{"key":"10.1016\/j.nutres.2018.06.004_bb0215","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1126\/science.7624777","article-title":"Weight-reducing effects of the plasma protein encoded by the obese gene","volume":"269","author":"Halaas","year":"1995","journal-title":"Science"},{"key":"10.1016\/j.nutres.2018.06.004_bb0220","doi-asserted-by":"crossref","first-page":"12916","DOI":"10.1021\/jf102840w","article-title":"Green and black tea suppress hyperglycemia and insulin resistance by retaining the expression of glucose transporter 4 in muscle of high-fat diet-fed C57BL\/6J mice","volume":"58","author":"Nishiumi","year":"2010","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.nutres.2018.06.004_bb0225","doi-asserted-by":"crossref","first-page":"E1444","DOI":"10.1152\/ajpendo.00434.2013","article-title":"Effects of the green tea polyphenol epigallocatechin-3-gallate on high-fat diet-induced insulin resistance and endothelial dysfunction","volume":"305","author":"Jang","year":"2013","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.nutres.2018.06.004_bb0230","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1038\/sj.ijo.0801209","article-title":"Development of high fat diet-induced obesity and leptin resistance in C57Bl\/6J mice","volume":"24","author":"Lin","year":"2000","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1016\/j.nutres.2018.06.004_bb0235","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/S0026-0495(98)90037-3","article-title":"High-monounsaturated fat diet-induced obesity and diabetes in C57BL\/6J mice","volume":"47","author":"Tsunoda","year":"1998","journal-title":"Metabolism"},{"key":"10.1016\/j.nutres.2018.06.004_bb0240","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1038\/sj.ijo.0801404","article-title":"Plasma leptin concentrations and obesity in relation to insulin resistance syndrome components among school children in Taiwan--The Taipei Children Heart Study","volume":"24","author":"Chu","year":"2000","journal-title":"Int J Obes Relat Metab Disord"},{"key":"10.1016\/j.nutres.2018.06.004_bb0245","doi-asserted-by":"crossref","first-page":"988","DOI":"10.2337\/diab.45.7.988","article-title":"Relationship between insulin sensitivity and plasma leptin concentration in lean and obese men","volume":"45","author":"Segal","year":"1996","journal-title":"Diabetes"},{"key":"10.1016\/j.nutres.2018.06.004_bb0250","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1136\/bmj.313.7063.965","article-title":"Serum leptin concentration, obesity, and insulin resistance in Western Samoans: cross sectional study","volume":"313","author":"Zimmet","year":"1996","journal-title":"BMJ"},{"key":"10.1016\/j.nutres.2018.06.004_bb0255","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/oby.2003.74","article-title":"Systemic inflammation, adipose tissue tumor necrosis factor, and leptin expression","volume":"11","author":"Bullo","year":"2003","journal-title":"Obes Res"},{"key":"10.1016\/j.nutres.2018.06.004_bb0260","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.jacc.2008.05.060","article-title":"Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease","volume":"52","author":"Martin","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.nutres.2018.06.004_bb0265","doi-asserted-by":"crossref","first-page":"699","DOI":"10.2337\/diab.45.5.699","article-title":"Acute and chronic effects of insulin on leptin production in humans: Studies in vivo and in vitro","volume":"45","author":"Kolaczynski","year":"1996","journal-title":"Diabetes"},{"key":"10.1016\/j.nutres.2018.06.004_bb0270","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.2337\/diab.45.10.1435","article-title":"Insulin and cortisol promote leptin production in cultured human fat cells","volume":"45","author":"Wabitsch","year":"1996","journal-title":"Diabetes"},{"key":"10.1016\/j.nutres.2018.06.004_bb0275","doi-asserted-by":"crossref","first-page":"R5","DOI":"10.1677\/joe.0.155r005","article-title":"Leptin inhibits insulin binding in isolated rat adipocytes","volume":"155","author":"Walder","year":"1997","journal-title":"J Endocrinol"},{"key":"10.1016\/j.nutres.2018.06.004_bb0280","doi-asserted-by":"crossref","first-page":"10585","DOI":"10.1074\/jbc.272.16.10585","article-title":"Leptin impairs metabolic actions of insulin in isolated rat adipocytes","volume":"272","author":"Muller","year":"1997","journal-title":"J Biol Chem"},{"key":"10.1016\/j.nutres.2018.06.004_bb0285","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1016\/S0196-9781(97)00135-6","article-title":"Leptin: a potent inhibitor of insulin secretion","volume":"18","author":"Fehmann","year":"1997","journal-title":"Peptides"},{"key":"10.1016\/j.nutres.2018.06.004_bb0290","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fendo.2017.00300","article-title":"Editorial: leptin resistance in metabolic disorders: possible mechanisms and treatments","volume":"8","author":"Hosoi","year":"2017","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.nutres.2018.06.004_bb0295","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1007\/s11626-013-9629-x","article-title":"Participation of leptin in the determination of the macrophage phenotype: an additional role in adipocyte and macrophage crosstalk","volume":"49","author":"Acedo","year":"2013","journal-title":"In Vitro Cell Dev Biol Anim"},{"key":"10.1016\/j.nutres.2018.06.004_bb0300","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/1758-5996-5-31","article-title":"Chronic inflammation role in the obesity-diabetes association: a case-cohort study","volume":"5","author":"Luft","year":"2013","journal-title":"Diabetol Metab Syndr"},{"key":"10.1016\/j.nutres.2018.06.004_bb0305","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1038\/leu.2009.65","article-title":"Mesenchymal stem cells from multiple myeloma patients display distinct genomic profile as compared with those from normal donors","volume":"23","author":"Garayoa","year":"2009","journal-title":"Leukemia"},{"key":"10.1016\/j.nutres.2018.06.004_bb0310","doi-asserted-by":"crossref","first-page":"E7239","DOI":"10.1073\/pnas.1500396113","article-title":"CD11b regulates obesity-induced insulin resistance via limiting alternative activation and proliferation of adipose tissue macrophages","volume":"112","author":"Zheng","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.nutres.2018.06.004_bb0315","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1189\/jlb.71.4.597","article-title":"Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages","volume":"71","author":"Raes","year":"2002","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.nutres.2018.06.004_bb0320","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0165-2478(02)00225-0","article-title":"Macrophages in chronic type 2 inflammation have a novel phenotype characterized by the abundant expression of Ym1 and Fizz1 that can be partly replicated in vitro","volume":"85","author":"Nair","year":"2003","journal-title":"Immunol Lett"},{"key":"10.1016\/j.nutres.2018.06.004_bb0325","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0060185","article-title":"Transcriptional suppression, DNA methylation, and histone deacetylation of the regulator of G-protein signaling 10 (RGS10) gene in ovarian cancer cells","volume":"8","author":"Ali","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2018.06.004_bb0330","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1046\/j.1471-4159.2002.01002.x","article-title":"Regulation of regulators of G protein signaling mRNA expression in rat brain by acute and chronic electroconvulsive seizures","volume":"82","author":"Gold","year":"2002","journal-title":"J Neurochem"},{"key":"10.1016\/j.nutres.2018.06.004_bb0335","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.neurobiolaging.2015.02.006","article-title":"Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration","volume":"36","author":"Kannarkat","year":"2015","journal-title":"Neurobiol Aging"},{"key":"10.1016\/j.nutres.2018.06.004_bb0340","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/aps.2015.11","article-title":"Green tea polyphenol epigallocatechin-3-gallate ameliorates insulin resistance in non-alcoholic fatty liver disease mice","volume":"36","author":"Gan","year":"2015","journal-title":"Acta Pharmacol Sin"}],"container-title":["Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531718302008?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531718302008?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T23:48:25Z","timestamp":1759448905000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0271531718302008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10]]},"references-count":68,"alternative-id":["S0271531718302008"],"URL":"https:\/\/doi.org\/10.1016\/j.nutres.2018.06.004","relation":{},"ISSN":["0271-5317"],"issn-type":[{"value":"0271-5317","type":"print"}],"subject":[],"published":{"date-parts":[[2019,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Depletion of regulator-of-G-protein signaling-10 in mice exaggerates high-fat diet-induced insulin resistance and inflammation, and this effect is mitigated by dietary green tea extract","name":"articletitle","label":"Article Title"},{"value":"Nutrition Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nutres.2018.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}