{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T19:06:46Z","timestamp":1781204806790,"version":"3.54.1"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,4,1]],"date-time":"2019-04-01T00:00:00Z","timestamp":1554076800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition Research"],"published-print":{"date-parts":[[2019,4]]},"DOI":"10.1016\/j.nutres.2018.12.012","type":"journal-article","created":{"date-parts":[[2018,12,29]],"date-time":"2018-12-29T03:52:13Z","timestamp":1546055533000},"page":"56-63","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Apple intake improves antioxidant parameters in hemodialysis patients without affecting serum potassium levels"],"prefix":"10.1016","volume":"64","author":[{"given":"Andr\u00e9ia G.","family":"Giaretta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayara","family":"Schulz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ta\u00eds T.","family":"Silveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina V.","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayara J.","family":"Patr\u00edcio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano V.","family":"Gonzaga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roseane","family":"Fett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edson L.","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Wazlawik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nutres.2018.12.012_bb0005","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1093\/ejcts\/ezt637","article-title":"Oxidative stress during extracorporeal circulation","volume":"46","author":"McDonald","year":"2014","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.nutres.2018.12.012_bb0010","series-title":"Free radical in biology and medicine","first-page":"87","article-title":"Cellular responses to oxidative stress: Adaptation, damage, repair, senescence and death","author":"Halliwell","year":"2007"},{"key":"10.1016\/j.nutres.2018.12.012_bb0015","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.freeradbiomed.2012.05.013","article-title":"One year of pomegranate juice intake decreases oxidative stress, inflammation, and incidence of infections in hemodialysis patients: a randomized placebo-controlled trial","volume":"53","author":"Shema-Didi","year":"2012","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.nutres.2018.12.012_bb0020","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.maturitas.2016.04.001","article-title":"Novel functional foods for optimal oxidative status in healthy ageing","volume":"93","author":"Da Silva","year":"2016","journal-title":"Maturitas"},{"key":"10.1016\/j.nutres.2018.12.012_bb0025","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1053\/j.jrn.2015.11.004","article-title":"Dietary quality and adherence to dietary recommendations in patients undergoing hemodialysis","volume":"26","author":"Luis","year":"2016","journal-title":"J Ren Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0030","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1053\/j.jrn.2015.10.002","article-title":"Exploring problems in following the hemodialysis diet and their relation to energy and nutrient intakes: the BalanceWise study","volume":"26","author":"St-Jules","year":"2016","journal-title":"J Ren Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/sdi.12030","article-title":"Is vitamin C intake too low in dialysis patients?","volume":"26","author":"Raimann","year":"2013","journal-title":"Semin Dial"},{"key":"10.1016\/j.nutres.2018.12.012_bb0040","doi-asserted-by":"crossref","first-page":"3372","DOI":"10.1158\/1055-9965.EPI-08-0364","article-title":"Anthocyanin\/polyphenolic-rich fruit juice reduces oxidative cell damage in an intervention study with patients on hemodialysis","volume":"17","author":"Spormann","year":"2008","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.nutres.2018.12.012_bb0045","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1055\/s-0028-1088300","article-title":"Cancer chemopreventive potential of apples, apple juice, and apple components","volume":"74","author":"Gerhauser","year":"2008","journal-title":"Planta Med"},{"key":"10.1016\/j.nutres.2018.12.012_bb0050","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1006\/abio.2001.5333","article-title":"High-throughput fluorescence screening of antioxidative capacity in human serum","volume":"297","author":"Mayer","year":"2001","journal-title":"Anal Biochem"},{"key":"10.1016\/j.nutres.2018.12.012_bb0055","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1080\/03610730701525352","article-title":"Effects of apple consumption on plasma and erythrocyte antioxidant parameters in elderly subjects","volume":"33","author":"Avci","year":"2007","journal-title":"Exp Aging Res"},{"key":"10.1016\/j.nutres.2018.12.012_bb0060","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s00394-009-0088-9","article-title":"No effect of the farming system (organic\/conventional) on the bioavailability of apple (Malus domestica Bork) polyphenols in healthy men: a comparative study","volume":"49","author":"Stracke","year":"2010","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0065","doi-asserted-by":"crossref","first-page":"390","DOI":"10.3390\/molecules17010390","article-title":"Variations of antioxidant characteristics and mineral contents in pulp and peel of different apple (Malus domestica Borkh) cultivars from Pakistan","volume":"17","author":"Manzoor","year":"2012","journal-title":"Molecules"},{"key":"10.1016\/j.nutres.2018.12.012_bb0070","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3109\/09637480903514041","article-title":"Daily consumption of apple, pear and orange juice differently affects plasma lipids and antioxidant capacity of smoking and non-smoking adults","volume":"61","author":"Alvarez-Parrilla","year":"2010","journal-title":"Int J Food Sci Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0075","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1021\/jf0015266","article-title":"Fate of apple peel phenolics during cool storage","volume":"49","author":"Golding","year":"2001","journal-title":"J Agric Food Chem"},{"key":"10.1016\/j.nutres.2018.12.012_bb0080","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1111\/j.1750-3841.2012.02770.x","article-title":"Efficacy of different sanitizing agents and their combination on microbe population and quality of fresh-cut Chinese chives","volume":"77","author":"Dai","year":"2012","journal-title":"J Food Sci"},{"key":"10.1016\/j.nutres.2018.12.012_bb0085","series-title":"Official methods of analysis","author":"Association of Official Analytical Chemists (AOAC)","year":"2005"},{"key":"10.1016\/j.nutres.2018.12.012_bb0090","doi-asserted-by":"crossref","first-page":"144","DOI":"10.5344\/ajev.1965.16.3.144","article-title":"Colorimetry of total phenolics with phosphomolybdic phosphotungstic acid reagents","volume":"16","author":"Singleton","year":"1965","journal-title":"Am J Enol Vitic"},{"key":"10.1016\/j.nutres.2018.12.012_bb0095","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1006\/jfca.2002.1070","article-title":"Correlation of pigment and flavonol content with antioxidant properties in selected aged regional wines from Greece","volume":"15","author":"Arnous","year":"2002","journal-title":"J Food Composit Anal"},{"key":"10.1016\/j.nutres.2018.12.012_bb0100","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S0023-6438(95)80008-5","article-title":"Use of free radical method to evaluate antioxidant activity","volume":"28","author":"Brand-Williams","year":"1995","journal-title":"LWT Food Sci Technol"},{"key":"10.1016\/j.nutres.2018.12.012_bb0105","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of antioxidant power: the FRAP assay","volume":"239","author":"Benzie","year":"1996","journal-title":"Anal Biochem"},{"key":"10.1016\/j.nutres.2018.12.012_bb0110","series-title":"Current protocols in food analytical chemistry","first-page":"1","article-title":"Anthocyanins: Characterization and measurement with UV-visible spectroscopy","author":"Giusti","year":"2001"},{"key":"10.1016\/j.nutres.2018.12.012_bb0115","author":"National Kidney Foundation (NKF)"},{"key":"10.1016\/j.nutres.2018.12.012_bb0120","author":"National Kidney Foundation (NKF)"},{"key":"10.1016\/j.nutres.2018.12.012_bb0125","first-page":"1199","article-title":"A cadeia produtiva da ma\u00e7\u00e3 em Santa Catarina: competitividade segundo produ\u00e7\u00e3o e packing house","volume":"45","author":"Bittencourt","year":"2011","journal-title":"RAP"},{"key":"10.1016\/j.nutres.2018.12.012_bb0130","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1038\/nprot.2013.095","article-title":"Analysis of GSH and GSSG after derivatization with N-ethylmaleimide","volume":"8","author":"Giustarini","year":"2013","journal-title":"Nat Protoc"},{"key":"10.1016\/j.nutres.2018.12.012_bb0135","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/j.clinbiochem.2003.11.015","article-title":"A novel automated direct measurement method for total antioxidant capacity using a new generation, more stable ABTS radical cation","volume":"37","author":"Erel","year":"2004","journal-title":"Clin Biochem"},{"key":"10.1016\/j.nutres.2018.12.012_bb0140","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0009-9120(01)00270-3","article-title":"Plasma ascorbic acid: measurement, stability and clinical utility revisited","volume":"34","author":"Chung","year":"2001","journal-title":"Clin Biochem"},{"key":"10.1016\/j.nutres.2018.12.012_bb0145","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/0003-2697(88)90554-4","article-title":"A spectophotometric method for determination of catalase activity in small tissue samples","volume":"174","author":"Johansson","year":"1988","journal-title":"Anal Biochem"},{"key":"10.1016\/j.nutres.2018.12.012_bb0150","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0076-6879(81)77046-0","article-title":"Glutathione peroxidase","volume":"77","author":"Wendel","year":"1981","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.nutres.2018.12.012_bb0155","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.clinbiochem.2005.08.008","article-title":"A new automated colorimetric method for measuring total oxidant status","volume":"38","author":"Erel","year":"2005","journal-title":"Clin Biochem"},{"key":"10.1016\/j.nutres.2018.12.012_bb0160","doi-asserted-by":"crossref","first-page":"273","DOI":"10.5021\/ad.2013.25.3.273","article-title":"Total serum oxidant\/antioxidant status and arylesterase activity in recurrent aphthous stomatitis","volume":"25","author":"Akoglu","year":"2013","journal-title":"Ann Dermatol"},{"key":"10.1016\/j.nutres.2018.12.012_bb0165","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1037\/0033-2909.112.1.155","article-title":"A power primer","volume":"112","author":"Cohen","year":"1993","journal-title":"Psychol Bull"},{"key":"10.1016\/j.nutres.2018.12.012_bb0170","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1007\/s00204-011-0674-5","article-title":"The cytoprotective role of the Keap1-Nrf2 pathway","volume":"85","author":"Baird","year":"2011","journal-title":"Arch Toxicol"},{"key":"10.1016\/j.nutres.2018.12.012_bb0175","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s00394-010-0124-9","article-title":"Apple juice intervention modulates expression of are-dependent genes in rat colon and liver","volume":"50","author":"Soyalan","year":"2011","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0180","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0053725","article-title":"Apple peel polyphenols and their beneficial actions on oxidative stress and inflammation","volume":"8","author":"Denis","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2018.12.012_bb0185","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.nutres.2014.10.010","article-title":"Pine bark extract prevents low-density lipoprotein oxidation and regulates monocytic expression of antioxidant enzymes","volume":"35","author":"Nakayamaa","year":"2015","journal-title":"Nutr Res"},{"key":"10.1016\/j.nutres.2018.12.012_bb0190","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1002\/biof.1288","article-title":"Curcuma longa polyphenols improve insulin-mediated lipid accumulation and attenuate proinflammatory response of 3T3-L1 adipose cells during oxidative stress through regulation of key adipokines and antioxidant enzymes","volume":"42","author":"Septembre-Malaterre","year":"2016","journal-title":"Biofactors"},{"key":"10.1016\/j.nutres.2018.12.012_bb0195","first-page":"39","article-title":"Acute effects of hemodialysis on oxidative stress parameters in chronic uremic patients: comparison of two dialysis membranes","volume":"3","author":"Varan","year":"2010","journal-title":"Int J Nephrol Renovasc Dis"},{"key":"10.1016\/j.nutres.2018.12.012_bb0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4172\/scientificreports.413","article-title":"An overview of oxidative stress and antioxidant defensive system","volume":"1","author":"Noori","year":"2012","journal-title":"J Clin Cell Immunol"},{"key":"10.1016\/j.nutres.2018.12.012_bb0205","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1007\/s00394-014-0670-7","article-title":"Effects of regular consumption of vitamin C-rich or polyphenol-rich apple juice on cardiometabolic markers in healthy adults: a randomized crossover trial","volume":"53","author":"Soriano-Maldonado","year":"2014","journal-title":"Eur J Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0210","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1053\/j.jrn.2014.09.007","article-title":"Plasma ascorbic acid concentrations in prevalent patients with end-stage renal disease on hemodialysis","volume":"25","author":"Sirover","year":"2015","journal-title":"J Ren Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0215","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1017\/S0007114507665192","article-title":"Relevance of apple consumption for protection against oxidative damage induced by hydrogen peroxide in human lymphocytes","volume":"97","author":"Maffei","year":"2007","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0220","doi-asserted-by":"crossref","first-page":"1727","DOI":"10.1016\/j.freeradbiomed.2006.04.033","article-title":"Consumption of flavonoid-rich foods and increased plasma antioxidant capacity in humans: cause, consequence, or epiphenomenon?","volume":"41","author":"Lotito","year":"2006","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.nutres.2018.12.012_bb0225","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1038\/ejcn.2010.135","article-title":"The regular consumption of a polyphenol-rich apple does not influence endothelial function: a randomised double-blind trial in hypercholesterolemic adults","volume":"64","author":"Auclair","year":"2010","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0230","first-page":"14","article-title":"Differences in pharmacokinetics of apple polyphenols after standardized oral consumption of unprocessed apple juice","volume":"1","author":"Wruss","year":"2015","journal-title":"Nutr J"},{"key":"10.1016\/j.nutres.2018.12.012_bb0235","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.nutres.2011.12.008","article-title":"Improvement of serum antioxidant status in humans after the acute intake of apple juices","volume":"32","author":"Vieira","year":"2012","journal-title":"Nutr Res"},{"key":"10.1016\/j.nutres.2018.12.012_bb0240","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1177\/2040622311430006","article-title":"Evidence for a protective effect of polyphenols-containing foods on cardiovascular health: an update for clinicians","volume":"3","author":"Habauzit","year":"2012","journal-title":"Ther Adv Chronic Dis"},{"key":"10.1016\/j.nutres.2018.12.012_bb0245","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1007\/s00005-006-0040-0","article-title":"Increased whole blood chemiluminescence in patients with chronic renal failure independent of hemodialysis treatment","volume":"54","author":"Rysz","year":"2006","journal-title":"Arch Immunol Ther Exp (Warsz)"},{"key":"10.1016\/j.nutres.2018.12.012_bb0250","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.nutres.2013.04.004","article-title":"Pomegranate juice intake attenuates the increase in oxidative stress induced by intravenous iron during hemodialysis","volume":"33","author":"Shema-Didi","year":"2013","journal-title":"Nutr Res"},{"key":"10.1016\/j.nutres.2018.12.012_bb0255","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1093\/ajcn\/84.1.252","article-title":"Concentrated red grape juice exerts antioxidant, hypolipidemic, and antiinflammatory effects in both hemodialysis patients and healthy subjects","volume":"84","author":"Castilla","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"10.1016\/j.nutres.2018.12.012_bb0260","doi-asserted-by":"crossref","first-page":"S-126","DOI":"10.1046\/j.1523-1755.2000.07616.x","article-title":"Oxidant stress in hemodialysis: prevention and treatment strategies","volume":"58","author":"Wratten","year":"2000","journal-title":"Kidney Int Suppl"},{"key":"10.1016\/j.nutres.2018.12.012_bb0265","doi-asserted-by":"crossref","first-page":"1668","DOI":"10.1046\/j.1523-1755.2000.00011.x","article-title":"Multistate outbreak of hemolysis in hemodialysis patients traced to faulty blood tubing sets","volume":"57","author":"Dufft","year":"2000","journal-title":"Kidney Int"},{"key":"10.1016\/j.nutres.2018.12.012_bb0270","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/s12882-016-0282-y","article-title":"A practical approach to dietary interventions for nondialysis-dependent CKD patients: the experience of a reference nephrology center in Brazil","volume":"17","author":"Cuppari","year":"2016","journal-title":"BMC Nephrol"},{"key":"10.1016\/j.nutres.2018.12.012_bb0275","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0147329","article-title":"The incidence of endstage renal disease in the diabetic (compared to the non-diabetic) population: a systematic review","volume":"11","author":"Narres","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.nutres.2018.12.012_bb0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/nu8010017","article-title":"Polyphenols and glycemic control","volume":"8","author":"Kim","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.nutres.2018.12.012_bb0285","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.krcp.2015.02.004","article-title":"Effect of acute intradialytic strength physical exercise on oxidative stress and inflammatory responses in hemodialysis patients","volume":"34","author":"Esgalhado","year":"2015","journal-title":"Kidney Res Clin Pract"},{"key":"10.1016\/j.nutres.2018.12.012_bb0290","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3109\/1354750X.2013.867533","article-title":"Variability of oxidative stress biomarkers in hemodialysis patients","volume":"19","author":"Dahwa","year":"2014","journal-title":"Biomarkers"},{"key":"10.1016\/j.nutres.2018.12.012_bb0295","first-page":"1363","article-title":"Effects of fermentable dietary fiber supplementation on oxidative and inflammatory status in hemodialysis patients","volume":"8","author":"Xie","year":"2015","journal-title":"Int J Clin Exp Med"}],"container-title":["Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531718305827?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531718305827?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T14:35:08Z","timestamp":1694529308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0271531718305827"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4]]},"references-count":59,"alternative-id":["S0271531718305827"],"URL":"https:\/\/doi.org\/10.1016\/j.nutres.2018.12.012","relation":{},"ISSN":["0271-5317"],"issn-type":[{"value":"0271-5317","type":"print"}],"subject":[],"published":{"date-parts":[[2019,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Apple intake improves antioxidant parameters in hemodialysis patients without affecting serum potassium levels","name":"articletitle","label":"Article Title"},{"value":"Nutrition Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nutres.2018.12.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}