{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T12:35:05Z","timestamp":1789907705262,"version":"4.0.1"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Nutrition Research"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.nutres.2024.06.009","type":"journal-article","created":{"date-parts":[[2024,7,3]],"date-time":"2024-07-03T20:37:57Z","timestamp":1720039077000},"page":"94-104","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Dietary and circulating branched chain amino acids are unfavorably associated with body fat measures among Chinese adults"],"prefix":"10.1016","volume":"128","author":[{"given":"Yaozong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Songxian","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohong","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoyu","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjuan","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7365-2689","authenticated-orcid":false,"given":"Wanshui","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.nutres.2024.06.009_bib0001","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1016\/j.celrep.2016.05.092","article-title":"Decreased consumption of branched-chain amino acids improves metabolic health","volume":"16","author":"Fontana","year":"2016","journal-title":"Cell Rep"},{"key":"10.1016\/j.nutres.2024.06.009_bib0002","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1113\/JP275075","article-title":"Restoration of metabolic health by decreased consumption of branched-chain amino acids","volume":"596","author":"Cummings","year":"2018","journal-title":"J Physiol"},{"key":"10.1016\/j.nutres.2024.06.009_bib0003","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1123\/ijsnem.2023-0015","article-title":"Co-ingestion of branched-chain amino acids and carbohydrate stimulates myofibrillar protein synthesis following resistance exercise in trained young men","volume":"33","author":"Jackman","year":"2023","journal-title":"Int J Sport Nutr Exerc Metab"},{"key":"10.1016\/j.nutres.2024.06.009_bib0004","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.3390\/nu12051429","article-title":"Effects of branched-chain amino acid (bcaa) supplementation on the progression of advanced liver disease: A korean nationwide, multicenter, prospective, observational, cohort study","volume":"12","author":"Park","year":"2020","journal-title":"Nutrients"},{"key":"10.1016\/j.nutres.2024.06.009_bib0005","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.ijcard.2016.08.307","article-title":"Associations between branched chain amino acid intake and biomarkers of adiposity and cardiometabolic health independent of genetic factors: a twin study","volume":"223","author":"Jennings","year":"2016","journal-title":"Int J Cardiol"},{"key":"10.1016\/j.nutres.2024.06.009_bib0006","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s12603-015-0521-0","article-title":"Consumption of branched-chain amino acids is inversely associated with central obesity and cardiometabolic features in a population of brazilian middle-aged men: Potential role of leucine intake","volume":"19","author":"Cogate","year":"2015","journal-title":"J Nutr Health Aging"},{"key":"10.1016\/j.nutres.2024.06.009_bib0007","doi-asserted-by":"crossref","first-page":"9573","DOI":"10.3390\/nu7115486","article-title":"The ratio of dietary branched-chain amino acids is associated with a lower prevalence of obesity in young northern Chinese adults: an internet-based cross-sectional study","volume":"7","author":"Li","year":"2015","journal-title":"Nutrients"},{"key":"10.1016\/j.nutres.2024.06.009_bib0008","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3945\/jn.110.128520","article-title":"Higher branched-chain amino acid intake is associated with a lower prevalence of being overweight or obese in middle-aged east Asian and western adults","volume":"141","author":"Qin","year":"2011","journal-title":"J Nutr"},{"key":"10.1016\/j.nutres.2024.06.009_bib0009","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1007\/s40519-021-01266-6","article-title":"Dietary intake of branched-chain amino acids in relation to general and abdominal obesity","volume":"27","author":"Asoudeh","year":"2022","journal-title":"Eat Weight Disord"},{"key":"10.1016\/j.nutres.2024.06.009_bib0010","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1002\/oby.22834","article-title":"Daily branched-chain amino acid intake and risks of obesity and insulin resistance in children: a cross-sectional study","volume":"28","author":"Lu","year":"2020","journal-title":"Obesity (Silver Spring)"},{"key":"10.1016\/j.nutres.2024.06.009_bib0011","first-page":"173","article-title":"Dietary consumption of branched-chain amino acids among Chinese middle-aged and elderly population aged 50 and over in 2015","volume":"52","author":"Yu","year":"2023","journal-title":"Wei Sheng Yan Jiu"},{"key":"10.1016\/j.nutres.2024.06.009_bib0012","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1093\/ije\/dyw143","article-title":"Cumulative consumption of branched-chain amino acids and incidence of type 2 diabetes","volume":"45","author":"Zheng","year":"2016","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.nutres.2024.06.009_bib0013","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/MCO.0000000000000614","article-title":"Effect of branched-chain amino acid supplementation, dietary intake and circulating levels in cardiometabolic diseases: an updated review","volume":"23","author":"de la","year":"2020","journal-title":"Curr Opin Clin Nutr Metab Care"},{"key":"10.1016\/j.nutres.2024.06.009_bib0014","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1146\/annurev-physiol-020518-114455","article-title":"Branched chain amino acids","volume":"81","author":"Neinast","year":"2019","journal-title":"Annu Rev Physiol"},{"key":"10.1016\/j.nutres.2024.06.009_bib0015","doi-asserted-by":"crossref","first-page":"5709","DOI":"10.1021\/acs.analchem.0c04686","article-title":"A metabolite array technology for precision medicine","volume":"93","author":"Xie","year":"2021","journal-title":"Anal Chem"},{"key":"10.1016\/j.nutres.2024.06.009_bib0016","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1249\/MSS.0b013e31821ece12","article-title":"2011 compendium of physical activities: a second update of codes and met values","volume":"43","author":"Ainsworth","year":"2011","journal-title":"Med Sci Sports Exerc"},{"key":"10.1016\/j.nutres.2024.06.009_bib0017","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1001\/archinte.168.7.713","article-title":"Adherence to a dash-style diet and risk of coronary heart disease and stroke in women","volume":"168","author":"Fung","year":"2008","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.nutres.2024.06.009_bib0018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S0954422419000155","article-title":"Dietary approaches to stop hypertension (dash): Potential mechanisms of action against risk factors of the metabolic syndrome","volume":"33","author":"Akhlaghi","year":"2020","journal-title":"Nutr Res Rev"},{"key":"10.1016\/j.nutres.2024.06.009_bib0019","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/liv.15057","article-title":"Higher dietary insulinaemic potential is associated with increased risk of liver steatosis and fibrosis","volume":"42","author":"Zhu","year":"2022","journal-title":"Liver Int"},{"key":"10.1016\/j.nutres.2024.06.009_bib0020","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/0197-2456(90)90005-M","article-title":"Power and sample size calculations. A review and computer program","volume":"11","author":"Dupont","year":"1990","journal-title":"Control Clin Trials"},{"key":"10.1016\/j.nutres.2024.06.009_bib0021","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1001\/jamainternmed.2022.6117","article-title":"Healthy eating patterns and risk of total and cause-specific mortality","volume":"183","author":"Shan","year":"2023","journal-title":"JAMA Intern Med"},{"key":"10.1016\/j.nutres.2024.06.009_bib0022","doi-asserted-by":"crossref","first-page":"390","DOI":"10.3389\/fphys.2017.00390","article-title":"Branched-chain amino acid ingestion stimulates muscle myofibrillar protein synthesis following resistance exercise in humans","volume":"8","author":"Jackman","year":"2017","journal-title":"Front Physiol"},{"key":"10.1016\/j.nutres.2024.06.009_bib0023","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1055\/s-2007-972594","article-title":"Combined effects of caloric restriction and branched-chain amino acid supplementation on body composition and exercise performance in elite wrestlers","volume":"18","author":"Mourier","year":"1997","journal-title":"Int J Sports Med"},{"key":"10.1016\/j.nutres.2024.06.009_bib0024","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.cmet.2009.02.002","article-title":"A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance","volume":"9","author":"Newgard","year":"2009","journal-title":"Cell Metab"},{"key":"10.1016\/j.nutres.2024.06.009_bib0025","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/nm.4057","article-title":"A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance","volume":"22","author":"Jang","year":"2016","journal-title":"Nat Med"},{"key":"10.1016\/j.nutres.2024.06.009_bib0026","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1038\/s42255-019-0059-2","article-title":"Branched chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control","volume":"1","author":"Solon-Biet","year":"2019","journal-title":"Nat Metab"},{"key":"10.1016\/j.nutres.2024.06.009_bib0027","doi-asserted-by":"crossref","first-page":"e6","DOI":"10.1017\/jns.2015.37","article-title":"Associations between plasma branched-chain amino acids, beta-aminoisobutyric acid and body composition","volume":"5","author":"Rietman","year":"2016","journal-title":"J Nutr Sci"},{"key":"10.1016\/j.nutres.2024.06.009_bib0028","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1002\/hep.29465","article-title":"Altered amino acid concentrations in nafld: Impact of obesity and insulin resistance","volume":"67","author":"Gaggini","year":"2018","journal-title":"Hepatology"},{"key":"10.1016\/j.nutres.2024.06.009_bib0029","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1152\/physrev.00026.2020","article-title":"Regulation and metabolic functions of mtorc1 and mtorc2","volume":"101","author":"Szwed","year":"2021","journal-title":"Physiol Rev"},{"key":"10.1016\/j.nutres.2024.06.009_bib0030","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1038\/nrendo.2014.171","article-title":"Branched-chain amino acids in metabolic signalling and insulin resistance","volume":"10","author":"Lynch","year":"2014","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.nutres.2024.06.009_bib0031","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1152\/physrev.00063.2017","article-title":"Mechanisms of insulin action and insulin resistance","volume":"98","author":"Petersen","year":"2018","journal-title":"Physiol Rev"},{"key":"10.1016\/j.nutres.2024.06.009_bib0032","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature18646","article-title":"Human gut microbes impact host serum metabolome and insulin sensitivity","volume":"535","author":"Pedersen","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.nutres.2024.06.009_bib0033","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/s41574-018-0062-9","article-title":"Sarcopenic obesity in older adults: Aetiology, epidemiology and treatment strategies","volume":"14","author":"Batsis","year":"2018","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.nutres.2024.06.009_bib0034","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.arr.2014.12.001","article-title":"Aging and dyslipidemia: a review of potential mechanisms","volume":"19","author":"Liu","year":"2015","journal-title":"Ageing Res Rev"},{"key":"10.1016\/j.nutres.2024.06.009_bib0035","doi-asserted-by":"crossref","first-page":"368","DOI":"10.3389\/fendo.2019.00368","article-title":"Brown and beige adipose tissue and aging","volume":"10","author":"Zoico","year":"2019","journal-title":"Front Endocrinol (Lausanne)"},{"key":"10.1016\/j.nutres.2024.06.009_bib0036","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1172\/JCI64125","article-title":"The role of mitochondria in aging","volume":"123","author":"Bratic","year":"2013","journal-title":"J Clin Invest"},{"key":"10.1016\/j.nutres.2024.06.009_bib0037","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.freeradbiomed.2017.01.009","article-title":"High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mtorc1 activation","volume":"104","author":"Zhenyukh","year":"2017","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.nutres.2024.06.009_bib0038","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1096\/fasebj.10.2.8641567","article-title":"Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA","volume":"10","author":"de la Asuncion","year":"1996","journal-title":"FASEB J"},{"key":"10.1016\/j.nutres.2024.06.009_bib0039","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1161\/CIRCRESAHA.107.165472","article-title":"Role of mitochondrial dysfunction in insulin resistance","volume":"102","author":"Kim","year":"2008","journal-title":"Circ Res"},{"key":"10.1016\/j.nutres.2024.06.009_bib0040","doi-asserted-by":"crossref","first-page":"E495","DOI":"10.1152\/ajpendo.90424.2008","article-title":"Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats","volume":"297","author":"Gollisch","year":"2009","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.nutres.2024.06.009_bib0041","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s13105-019-00663-x","article-title":"Strength training and aerobic exercise alter mitochondrial parameters in brown adipose tissue and equally reduce body adiposity in aged rats","volume":"75","author":"Thirupathi","year":"2019","journal-title":"J Physiol Biochem"},{"key":"10.1016\/j.nutres.2024.06.009_bib0042","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1093\/gerona\/glz126","article-title":"Associations of fat and lean body mass with circulating amino acids in older men and women","volume":"75","author":"Mikkola","year":"2020","journal-title":"J Gerontol A Biol Sci Med Sci"},{"key":"10.1016\/j.nutres.2024.06.009_bib0043","doi-asserted-by":"crossref","first-page":"E366","DOI":"10.1152\/ajpendo.2000.279.2.E366","article-title":"Weight stability masks sarcopenia in elderly men and women","volume":"279","author":"Gallagher","year":"2000","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.nutres.2024.06.009_bib0044","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.ebiom.2019.04.005","article-title":"The impact of dietary protein intake on longevity and metabolic health","volume":"43","author":"Kitada","year":"2019","journal-title":"EBioMedicine"},{"key":"10.1016\/j.nutres.2024.06.009_bib0045","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1017\/S0007114514002475","article-title":"The effectiveness of leucine on muscle protein synthesis, lean body mass and leg lean mass accretion in older people: a systematic review and meta-analysis","volume":"113","author":"Xu","year":"2015","journal-title":"Br J Nutr"},{"key":"10.1016\/j.nutres.2024.06.009_bib0046","doi-asserted-by":"crossref","first-page":"954","DOI":"10.3390\/ijms19040954","article-title":"Branched chain amino acids: Beyond nutrition metabolism","volume":"19","author":"Nie","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.nutres.2024.06.009_bib0047","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/ejcn.2015.144","article-title":"Plasma concentrations and intakes of amino acids in male meat-eaters, fish-eaters, vegetarians and vegans: a cross-sectional analysis in the epic-oxford cohort","volume":"70","author":"Schmidt","year":"2016","journal-title":"Eur J Clin Nutr"},{"key":"10.1016\/j.nutres.2024.06.009_bib0048","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1373\/clinchem.2017.285841","article-title":"Dietary intakes and circulating concentrations of branched-chain amino acids in relation to incident type 2 diabetes risk among high-risk women with a history of gestational diabetes mellitus","volume":"64","author":"Tobias","year":"2018","journal-title":"Clin Chem"},{"key":"10.1016\/j.nutres.2024.06.009_bib0049","first-page":"11","article-title":"Associations between dietary protein sources, plasma BCAA and short-chain acylcarnitine levels in adults","author":"Rousseau","year":"2019","journal-title":"Nutrients"}],"container-title":["Nutrition Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531724000885?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0271531724000885?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T07:55:17Z","timestamp":1734508517000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0271531724000885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":49,"alternative-id":["S0271531724000885"],"URL":"https:\/\/doi.org\/10.1016\/j.nutres.2024.06.009","relation":{},"ISSN":["0271-5317"],"issn-type":[{"value":"0271-5317","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Dietary and circulating branched chain amino acids are unfavorably associated with body fat measures among Chinese adults","name":"articletitle","label":"Article Title"},{"value":"Nutrition Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.nutres.2024.06.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}