{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:49:58Z","timestamp":1791982198246,"version":"4.4.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T00:00:00Z","timestamp":1789430400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100032443","name":"Hong Kong Jockey Club","doi-asserted-by":"publisher","award":["_PPF-2021-101639"],"award-info":[{"award-number":["_PPF-2021-101639"]}],"id":[{"id":"10.13039\/100032443","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.jp","oarsiopenjournal.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Osteoarthritis and Cartilage Open"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.ocarto.2026.100878","type":"journal-article","created":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T23:49:30Z","timestamp":1790380170000},"page":"100878","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Clonal articular cartilage progenitors outperform mesenchymal stromal cells in mitigating post-traumatic osteoarthritis"],"prefix":"10.1016","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3087-9661","authenticated-orcid":false,"given":"Heidi","family":"Kloser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3583-4497","authenticated-orcid":false,"given":"Parvathy","family":"Thampi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4990-5006","authenticated-orcid":false,"given":"Lynn","family":"Pezzanite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-7073-4586","authenticated-orcid":false,"given":"Taryn","family":"Boxleitner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6413-9517","authenticated-orcid":false,"given":"Lyndah","family":"Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5488-9464","authenticated-orcid":false,"given":"Steve","family":"Dow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3750-4777","authenticated-orcid":false,"given":"Katie J.","family":"Sikes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2348-594X","authenticated-orcid":false,"given":"Kelly","family":"Santangelo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8010-4429","authenticated-orcid":false,"given":"Laurie","family":"Goodrich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7786-2870","authenticated-orcid":false,"given":"Brian","family":"Johnstone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.ocarto.2026.100878_bib1","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1002\/jor.23872","article-title":"Inflammatory and degenerative phases resulting from anterior cruciate rupture in a non-invasive murine model of post-traumatic osteoarthritis","volume":"36","author":"Gilbert","year":"2018","journal-title":"J. Orthop. Res."},{"issue":"SUPPL. 3","key":"10.1016\/j.ocarto.2026.100878_bib2","article-title":"The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the mouse","volume":"18","author":"Glasson","year":"2010","journal-title":"Osteoarthr. Cartil."},{"issue":"3","key":"10.1016\/j.ocarto.2026.100878_bib3","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jcot.2016.05.006","article-title":"Concepts in regenerative medicine: past, present, and future in articular cartilage treatment","volume":"7","author":"Anz","year":"2016","journal-title":"J Clin Orthop Trauma"},{"key":"10.1016\/j.ocarto.2026.100878_bib4","first-page":"117","article-title":"Mesenchymal stem cell therapy for osteoarthritis: current perspectives","volume":"8","author":"Wyles","year":"2015","journal-title":"Stem Cells Cloning"},{"key":"10.1016\/j.ocarto.2026.100878_bib5","article-title":"New approaches to treat osteoarthritis with mesenchymal stem cells","volume":"2018","author":"Shah","year":"2018","journal-title":"Stem Cell. Int."},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib6","article-title":"The effect of autologous adipose derived mesenchymal stem cell therapy in the treatment of a large osteochondral defect of the knee following unsuccessful surgical intervention of osteochondritis dissecans - a case study","volume":"18","author":"Freitag","year":"2017","journal-title":"BMC Muscoskelet. Disord."},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib7","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-017-0632-0","article-title":"Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix","volume":"8","author":"Wang","year":"2017","journal-title":"Stem Cell Res. Ther."},{"issue":"5","key":"10.1016\/j.ocarto.2026.100878_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/ijms22052499","article-title":"Evaluation of allogeneic bone-marrow-derived and umbilical cord blood-derived mesenchymal stem cells to prevent the development of osteoarthritis in an equine model","volume":"22","author":"Bertoni","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ocarto.2026.100878_bib9","series-title":"Equine Osteoarthritis: Strategies to Enhance Mesenchymal Stromal Cell-based Acellular Therapies","author":"Jammes","year":"2023"},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib10","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.stem.2015.06.007","article-title":"Stem cell therapies in clinical trials: progress and challenges","volume":"17","author":"Trounson","year":"2015","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib11","doi-asserted-by":"crossref","DOI":"10.1038\/s41536-019-0083-6","article-title":"Mesenchymal stem cell perspective: cell biology to clinical progress","volume":"4","author":"Pittenger","year":"2019","journal-title":"npj Regen. Med."},{"key":"10.1016\/j.ocarto.2026.100878_bib12","article-title":"Human placenta-derived mesenchymal stromal cells: a review from basic research to clinical applications","author":"Torre","year":"2018","journal-title":"Stromal Cells - Structure, Function, and Therapeutic Implications"},{"issue":"10","key":"10.1016\/j.ocarto.2026.100878_bib13","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1016\/j.joca.2012.06.003","article-title":"Mesenchymal stem cells secrete factors that inhibit inflammatory processes in short-term osteoarthritic synovium and cartilage explant culture","volume":"20","author":"van Buul","year":"2012","journal-title":"Osteoarthr. Cartil."},{"issue":"MAY","key":"10.1016\/j.ocarto.2026.100878_bib14","article-title":"The life and fate of mesenchymal stem cells","volume":"5","author":"Eggenhofer","year":"2014","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.ocarto.2026.100878_bib15","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1161\/01.CIR.0000124062.31102.57","article-title":"Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanisms","volume":"109","author":"Kinnaird","year":"2004","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.ocarto.2026.100878_bib16","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/jcp.21701","article-title":"Secretome from mesenchymal stem cells induces angiogenesis via Cyr61","volume":"219","author":"Estrada","year":"2009","journal-title":"J. Cell. Physiol."},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib17","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/mt.2011.211","article-title":"Mesenchymal stem\/stromal cells (MSCs): role as guardians of inflammation","volume":"20","author":"Prockop","year":"2012","journal-title":"Mol. Ther."},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib18","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13287-016-0420-2","article-title":"In vivo human adipose-derived mesenchymal stem cell tracking after intra-articular delivery in a rat osteoarthritis model","volume":"7","author":"Li","year":"2016","journal-title":"Stem Cell Res. Ther."},{"issue":"10","key":"10.1016\/j.ocarto.2026.100878_bib19","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1016\/j.joca.2012.06.002","article-title":"Intra-articular injection of human mesenchymal stem cells (MSCs) promote rat meniscal regeneration by being activated to express Indian hedgehog that enhances expression of type II collagen","volume":"20","author":"Horie","year":"2012","journal-title":"Osteoarthr. Cartil."},{"issue":"Pt 6","key":"10.1016\/j.ocarto.2026.100878_bib20","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1242\/jcs.00912","article-title":"The surface of articular cartilage contains a progenitor cell population","volume":"117","author":"Dowthwaite","year":"2004","journal-title":"J. Cell Sci."},{"issue":"5","key":"10.1016\/j.ocarto.2026.100878_bib21","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1002\/art.39030","article-title":"Identification of a Prg4-expressing articular cartilage progenitor cell population in mice","volume":"67","author":"Kozhemyakina","year":"2015","journal-title":"Arthritis Rheumatol."},{"issue":"4","key":"10.1016\/j.ocarto.2026.100878_bib22","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.joca.2008.08.002","article-title":"Clonal chondroprogenitors maintain telomerase activity and Sox 9 expression during extended monolayer culture and retain chondrogenic potential","volume":"17","author":"Khan","year":"2009","journal-title":"Osteoarthr. Cartil."},{"issue":"3","key":"10.1016\/j.ocarto.2026.100878_bib23","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.tvjl.2011.08.036","article-title":"The comparison of equine articular cartilage progenitor cells and bone marrow-derived stromal cells as potential cell sources for cartilage repair in the horse","volume":"192","author":"McCarthy","year":"2012","journal-title":"Vet. J."},{"issue":"11","key":"10.1016\/j.ocarto.2026.100878_bib24","doi-asserted-by":"crossref","first-page":"3626","DOI":"10.1002\/art.34613","article-title":"Chondrogenic progenitor cells respond to cartilage injury","volume":"64","author":"Seol","year":"2012","journal-title":"Arthritis Rheum."},{"issue":"10","key":"10.1016\/j.ocarto.2026.100878_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0013246","article-title":"Identification and clonal characterisation of a progenitor cell sub-population in normal human articular cartilage","volume":"5","author":"Williams","year":"2010","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib26","doi-asserted-by":"crossref","DOI":"10.1186\/s13287-016-0419-8","article-title":"Responses to altered oxygen tension are distinct between human stem cells of high and low chondrogenic capacity","volume":"7","author":"Anderson","year":"2016","journal-title":"Stem Cell Res. Ther."},{"issue":"3\u20134","key":"10.1016\/j.ocarto.2026.100878_bib27","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1089\/ten.tea.2016.0510","article-title":"Physioxia promotes the articular chondrocyte-like phenotype in human chondroprogenitor-derived self-organized tissue","volume":"24","author":"Anderson","year":"2018","journal-title":"Tissue Eng."},{"issue":"4","key":"10.1016\/j.ocarto.2026.100878_bib28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3109\/03008207.2015.1040547","article-title":"Potential benefits and limitations of utilizing chondroprogenitors in cell-based cartilage therapy","volume":"56","author":"Jayasuriya","year":"2015","journal-title":"Connect. Tissue Res."},{"issue":"4","key":"10.1016\/j.ocarto.2026.100878_bib29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1177\/1947603514544953","article-title":"Evidence of a viable pool of stem cells within human osteoarthritic cartilage","volume":"5","author":"Nelson","year":"2014","journal-title":"Cartilage"},{"issue":"6","key":"10.1016\/j.ocarto.2026.100878_bib30","doi-asserted-by":"crossref","first-page":"484","DOI":"10.2106\/JBJS.N.00404","article-title":"Evaluation of articular cartilage progenitor cells for the repair of articular defects in an equine model","volume":"97","author":"Frisbie","year":"2015","journal-title":"J. Bone Jt. Surg. Am. Vol."},{"issue":"5","key":"10.1016\/j.ocarto.2026.100878_bib31","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1634\/stemcells.22-5-675","article-title":"Study of telomere length reveals rapid aging of human marrow stromal cells following in vitro expansion","volume":"22","author":"Baxter","year":"2004","journal-title":"Stem Cell."},{"issue":"6","key":"10.1016\/j.ocarto.2026.100878_bib32","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/S0301-472X(00)00160-0","article-title":"Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells: implications for their use in cell therapy","volume":"28","author":"Banfi","year":"2000","journal-title":"Exp. Hematol."},{"issue":"6","key":"10.1016\/j.ocarto.2026.100878_bib33","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1002\/1529-0131(200106)44:6<1237::AID-ART214>3.0.CO;2-F","article-title":"Osteoarthritis, an inflammatory disease: potential implication for the selection of new therapeutic targets","volume":"44","author":"Pelletier","year":"2001","journal-title":"Arthritis Rheum."},{"issue":"6","key":"10.1016\/j.ocarto.2026.100878_bib34","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/1759720X10378373","article-title":"The role of synovitis in osteoarthritis","volume":"2","author":"Wenham","year":"2010","journal-title":"Ther Adv Musculoskelet Dis"},{"issue":"9","key":"10.1016\/j.ocarto.2026.100878_bib35","doi-asserted-by":"crossref","first-page":"311","DOI":"10.21037\/atm-22-4256","article-title":"Erythrocyte removal from bone marrow aspirate concentrate improves efficacy as intra-articular cellular therapy in a rodent osteoarthritis model","volume":"11","author":"Pezzanite","year":"2023","journal-title":"Ann. Transl. Med."},{"issue":"6","key":"10.1016\/j.ocarto.2026.100878_bib36","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.joca.2006.11.005","article-title":"Osteoarthritis severity is sex dependent in a surgical mouse model","volume":"15","author":"Ma","year":"2007","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.ocarto.2026.100878_bib37","article-title":"TLR4 antagonism provides short-term but not long-term clinical benefit in a full-depth cartilage defect mouse model","author":"Timkovich","year":"2023","journal-title":"Connect. Tissue Res."},{"issue":"3","key":"10.1016\/j.ocarto.2026.100878_bib38","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s10439-022-03065-1","article-title":"Full and partial mid-substance ACL rupture using mechanical tibial displacement in Male and female mice","volume":"51","author":"Timkovich","year":"2023","journal-title":"Ann. Biomed. Eng."},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib39","doi-asserted-by":"crossref","DOI":"10.1186\/s13075-022-02971-y","article-title":"Early removal of the infrapatellar fat pad\/synovium complex beneficially alters the pathogenesis of moderate stage idiopathic knee osteoarthritis in Male dunkin hartley Guinea pigs","volume":"24","author":"Afzali","year":"2022","journal-title":"Arthritis Res. Ther."},{"issue":"12","key":"10.1016\/j.ocarto.2026.100878_bib40","doi-asserted-by":"crossref","first-page":"1602","DOI":"10.1016\/j.joca.2023.07.013","article-title":"Streamlining quantitative joint-wide medial femoro-tibial histopathological scoring of mouse post-traumatic knee osteoarthritis models","volume":"31","author":"Haubruck","year":"2023","journal-title":"Osteoarthr. Cartil."},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib41","doi-asserted-by":"crossref","DOI":"10.1080\/20013078.2020.1735249","article-title":"Small extracellular vesicles from human adipose-derived stem cells attenuate cartilage degeneration","volume":"9","author":"Woo","year":"2020","journal-title":"J. Extracell. Vesicles"},{"issue":"4","key":"10.1016\/j.ocarto.2026.100878_bib42","doi-asserted-by":"crossref","first-page":"423","DOI":"10.3390\/jcm8040423","article-title":"Human diseased articular cartilage contains a mesenchymal stem cell-like population of chondroprogenitors with strong immunomodulatory responses","volume":"8","author":"De Luca","year":"2019","journal-title":"J. Clin. Med."},{"issue":"8","key":"10.1016\/j.ocarto.2026.100878_bib43","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1302\/2046-3758.118.BJR-2021-0575.R1","article-title":"Modelling osteoarthritis in mice via surgical destabilization of the medial meniscus with or without a stereomicroscope","volume":"11","author":"Hu","year":"2022","journal-title":"Bone Joint Res"},{"issue":"2","key":"10.1016\/j.ocarto.2026.100878_bib44","doi-asserted-by":"crossref","DOI":"10.1016\/j.ocarto.2020.100044","article-title":"Injected human umbilical cord-derived mesenchymal stromal cells do not appear to elicit an inflammatory response in a murine model of osteoarthritis","volume":"2","author":"Perry","year":"2020","journal-title":"Osteoarthr Cartil Open"},{"key":"10.1016\/j.ocarto.2026.100878_bib45","doi-asserted-by":"crossref","first-page":"218","DOI":"10.22203\/eCM.v036a16","article-title":"Mesenchymal stem cell secretome reduces pain and prevents cartilage damage in a murine osteoarthritis model","volume":"36","author":"Khatab","year":"2018","journal-title":"Eur. Cell. Mater."},{"key":"10.1016\/j.ocarto.2026.100878_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/9198328","article-title":"Intra-articular injection of human synovial membrane-derived mesenchymal stem cells in murine collagen-induced arthritis: assessment of immunomodulatory capacity in vivo","volume":"2017","author":"Yan","year":"2017","journal-title":"Stem Cell. Int."},{"issue":"3","key":"10.1016\/j.ocarto.2026.100878_bib47","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.berh.2014.08.002","article-title":"Burden of disability due to musculoskeletal (MSK) disorders","volume":"28","author":"March","year":"2014","journal-title":"Best Pract. Res. Clin. Rheumatol."},{"issue":"5","key":"10.1016\/j.ocarto.2026.100878_bib48","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1097\/00002281-200009000-00019","article-title":"Osteoarthritis pain and its treatment","volume":"12","author":"Creamer","year":"2000","journal-title":"Curr. Opin. Rheumatol."},{"issue":"4","key":"10.1016\/j.ocarto.2026.100878_bib49","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.biocel.2003.11.001","article-title":"Mesenchymal stem cells: clinical applications and biological characterization","volume":"36","author":"Barry","year":"2004","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"1","key":"10.1016\/j.ocarto.2026.100878_bib50","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.scr.2009.09.004","article-title":"Immune evasion by neocartilage-derived chondrocytes: implications for biologic repair of joint articular cartilage","volume":"4","author":"Adkisson","year":"2010","journal-title":"Stem Cell Res."}],"container-title":["Osteoarthritis and Cartilage Open"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665913126001366?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2665913126001366?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:14:17Z","timestamp":1791980057000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2665913126001366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":50,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,12]]}},"alternative-id":["S2665913126001366"],"URL":"https:\/\/doi.org\/10.1016\/j.ocarto.2026.100878","relation":{},"ISSN":["2665-9131"],"issn-type":[{"value":"2665-9131","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clonal articular cartilage progenitors outperform mesenchymal stromal cells in mitigating post-traumatic osteoarthritis","name":"articletitle","label":"Article Title"},{"value":"Osteoarthritis and Cartilage Open","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ocarto.2026.100878","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd on behalf of Osteoarthritis Research Society International (OARSI).","name":"copyright","label":"Copyright"}],"article-number":"100878"}}