{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T23:07:21Z","timestamp":1791068841931,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,7,1]],"date-time":"2020-07-01T00:00:00Z","timestamp":1593561600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.es","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda"],"published-print":{"date-parts":[[2020,7]]},"DOI":"10.1016\/j.oftal.2020.04.018","type":"journal-article","created":{"date-parts":[[2020,6,1]],"date-time":"2020-06-01T17:04:43Z","timestamp":1591031083000},"page":"334-344","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Medidas para prevenir los riesgos asociados con la exposici\u00f3n a citost\u00e1ticos en cirug\u00eda filtrante de glaucoma"],"prefix":"10.1016","volume":"95","author":[{"given":"A.","family":"Gonz\u00e1lez-Ventosa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Ariz-Juan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Sabater-Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.oftal.2020.04.018_bib0255","year":"2003","journal-title":"Protocolos de Vigilancia Sanitaria Espec\u00edfica: Agentes Citost\u00e1ticos"},{"key":"10.1016\/j.oftal.2020.04.018_bib0260","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1038\/nrc1074","article-title":"5-fluorouracil: mechanisms of action and clinical strategies","volume":"3","author":"Longley","year":"2003","journal-title":"Nat Rev Cancer."},{"key":"10.1016\/j.oftal.2020.04.018_bib0265","year":"2004","journal-title":"Preventing Occupational Exposure to Antineoplastic and Other Hazardous Drugs in Health Care Settings. Publication No. 2004-165"},{"key":"10.1016\/j.oftal.2020.04.018_bib0270","first-page":"1033","article-title":"ASHP technical assistance bulletin on handling cytotoxic and hazardous drugs","volume":"47","year":"1990","journal-title":"Am J Hop Pharm."},{"key":"10.1016\/j.oftal.2020.04.018_bib0275","year":"2016","journal-title":"NIOSH List of Antineoplastic and Other Hazardous Drugs in Healthcare Settings"},{"key":"10.1016\/j.oftal.2020.04.018_bib0280","first-page":"124","article-title":"Hazardous drugs: new challenges, new opportunities","volume":"40","author":"Valero Garc\u00eda","year":"2016","journal-title":"Farm Hosp."},{"key":"10.1016\/j.oftal.2020.04.018_bib0285","first-page":"257","article-title":"Impact of the new handling recommendations for hazardous drugs in a hospital pharmacy service","volume":"41","author":"Garc\u00eda Alc\u00e1ntara","year":"2017","journal-title":"Farm Hosp."},{"key":"10.1016\/j.oftal.2020.04.018_bib0290","year":"2015","journal-title":"Occupational health and safety risks in the healthcare sector: Guide to prevention and good practice"},{"key":"10.1016\/j.oftal.2020.04.018_bib0295","year":"2016","journal-title":"Medicamentos peligrosos: Medidas de prevenci\u00f3n para su preparaci\u00f3n y administraci\u00f3n"},{"key":"10.1016\/j.oftal.2020.04.018_bib0300","first-page":"1","article-title":"Some antineoplastic and immunosuppresive agents","volume":"26","year":"1981","journal-title":"IARC Monogr Eval Carcinog Risk Chem Hum."},{"key":"10.1016\/j.oftal.2020.04.018_bib0305","first-page":"57","article-title":"Toxicity of Antineoplastic Agents in Man: Chromosomal Aberrations, Antifertility Effects, Congenital Malformations, and Carcinogenic Potential","volume":"22","author":"Sieber","year":"1974","journal-title":"Advances in Cancer Research."},{"key":"10.1016\/j.oftal.2020.04.018_bib0310","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0165-1110(85)90024-7","article-title":"Occupational exposure to anticancer drugs --potential and real hazards","volume":"154","author":"Sorsa","year":"1985","journal-title":"Mutat Res."},{"key":"10.1016\/j.oftal.2020.04.018_bib0315","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0165-1218(79)90023-5","article-title":"Sister-chromatid exchanges and chromosal breakage in patients treated with cytostatics","volume":"67","author":"Musilov\u00e1","year":"1979","journal-title":"Mutat Res."},{"key":"10.1016\/j.oftal.2020.04.018_bib0320","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1093\/mutage\/gem032","article-title":"Genotoxicity assessment in oncology nurses handling antineoplastic drugs","volume":"22","author":"Rekhadevi","year":"2007","journal-title":"Mutagenesis."},{"key":"10.1016\/j.oftal.2020.04.018_bib0325","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0140-6736(84)90005-9","article-title":"Monitoring exposure of nursing and pharmacy personnel to cytotoxic drugs: urinary mutation assays and urinary platinum as markers of absorption","volume":"1","author":"Venitt","year":"1984","journal-title":"Lancet."},{"key":"10.1016\/j.oftal.2020.04.018_bib0330","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0140-6736(82)90474-3","article-title":"Urinary thioether excretion in nurses handling cytotoxic drugs","volume":"2","author":"Jagun","year":"1982","journal-title":"Lancet."},{"key":"10.1016\/j.oftal.2020.04.018_bib0335","doi-asserted-by":"crossref","first-page":"102","DOI":"10.5271\/sjweh.1811","article-title":"Risk of spontaneous abortion among nurses handling antineoplastic drugs","volume":"16","author":"St\u00fccker","year":"1990","journal-title":"Scand J Work Environ Health."},{"key":"10.1016\/j.oftal.2020.04.018_bib0340","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/BF00277812","article-title":"Occupational handling of cytostatic drugs","volume":"54","author":"Kolmodin-Hedman","year":"1983","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.oftal.2020.04.018_bib0345","doi-asserted-by":"crossref","first-page":"50","DOI":"10.5005\/jp-journals-10078-1254","article-title":"Glaucoma Surgery with Soaked Sponges with Mitomycin C vs Sub-Tenon Injection: Short-term Outcomes","volume":"13","author":"Guimar\u00e3es","year":"2019","journal-title":"J Curr Glaucoma Pract."},{"key":"10.1016\/j.oftal.2020.04.018_bib0350","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1111\/j.1755-3768.2007.01147.x","article-title":"Trabeculectomy surgery augmented with intra-Tenon injection of mitomycin C","volume":"86","author":"Lee","year":"2008","journal-title":"Acta Ophthalmol."},{"key":"10.1016\/j.oftal.2020.04.018_bib0355","first-page":"73","article-title":"Outcomes of Trabeculectomy With and Without Mitomycin C in Pseudoexfoliative Glaucoma Compared With Mitomycin C in Primary Open Angle Glaucoma","volume":"8","author":"Lopes","year":"2019","journal-title":"Med Hypothesis Discov Innov Ophthalmol."},{"key":"10.1016\/j.oftal.2020.04.018_bib0360","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ajo.2005.02.013","article-title":"Perioperative complications of trabeculectomy in the collaborative initial glaucoma treatment study (CIGTS)","volume":"140","author":"Jampel","year":"2005","journal-title":"Am J Ophthalmol."},{"key":"10.1016\/j.oftal.2020.04.018_bib0365","doi-asserted-by":"crossref","first-page":"216","DOI":"10.4103\/0974-9233.95255","article-title":"Office-based slit-lamp needle revision with adjunctive mitomycin-C for late failed or encapsulated filtering blebs","volume":"19","author":"Amini","year":"2012","journal-title":"Middle East Afr J Ophthalmol."},{"key":"10.1016\/j.oftal.2020.04.018_bib0370","first-page":"396","article-title":"Revisi\u00f3n por aguja de la bula de filtraci\u00f3n, una alternativa terap\u00e9utica en pacientes trabeculectomizados","volume":"25","author":"Arzuaga Hern\u00e1ndez","year":"2012","journal-title":"Rev Cubana de Oftalmol."},{"key":"10.1016\/j.oftal.2020.04.018_bib0375","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1097\/00061198-200502000-00009","article-title":"Needle revision of failed filtering blebs using 5-Fluorouracil and a combined ab-externo and ab-interno approach","volume":"14","author":"Pasternack","year":"2005","journal-title":"J Glaucoma."},{"key":"10.1016\/j.oftal.2020.04.018_bib0380","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.ophtha.2007.10.023","article-title":"Needling revision of trabeculectomies bleb morphology and long-term survival","volume":"115","author":"Rotchford","year":"2008","journal-title":"Ophthalmology."},{"key":"10.1016\/j.oftal.2020.04.018_bib0385","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.ophtha.2003.07.009","article-title":"Needle revision of failing and failed trabeculectomy blebs with adjunctive 5-fluorouracil: survival analysis","volume":"111","author":"Broadway","year":"2004","journal-title":"Ophthalmology."},{"key":"10.1016\/j.oftal.2020.04.018_bib0390","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1097\/IJG.0000000000000235","article-title":"Outcomes: Trabeculectomy Bleb Needle Revision With 5-Fluorouracil","volume":"25","author":"Zheng","year":"2016","journal-title":"J Glaucoma."},{"key":"10.1016\/j.oftal.2020.04.018_bib0395","first-page":"97","article-title":"Needling revision with subconjunctival 5- fluorouracil in failing filtering blebs","volume":"25","author":"Chang","year":"2002","journal-title":"Chang Gung Med J."},{"key":"10.1016\/j.oftal.2020.04.018_bib0400","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/IJG.0b013e3181911271","article-title":"Long-term outcomes of needle revision of trabeculectomy blebs with mitomycin C and 5-fluorouracil: A comparative safety and efficacy report","volume":"18","author":"Anand","year":"2009","journal-title":"J Glaucoma."},{"key":"10.1016\/j.oftal.2020.04.018_bib0405","doi-asserted-by":"crossref","first-page":"1946","DOI":"10.1016\/S0161-6420(96)30403-X","article-title":"Slit lamp needle revision of failed filtering blebs using mitomycin C","volume":"103","author":"Mardelli","year":"1996","journal-title":"Ophthamology."},{"key":"10.1016\/j.oftal.2020.04.018_bib0410","first-page":"295","article-title":"Needle revision with mitomycin-C in encapsulated blebs","volume":"46","author":"Zarei","year":"2008","journal-title":"Acta Med Iranica."},{"key":"10.1016\/j.oftal.2020.04.018_bib0415","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/j.1442-9071.2007.01483.x","article-title":"Non-penetrating glaucoma surgery augmented with mitomycin C or 5-fluorouracil in eyes at high risk of failure of filtration surgery: long-term results","volume":"35","author":"Choudhary","year":"2007","journal-title":"Clin Exp Ophthalmol."},{"key":"10.1016\/j.oftal.2020.04.018_bib0420","first-page":"4","article-title":"Safe handling of oral chemotherapeutic agents: A European perspective","volume":"5","author":"Meier","year":"2011","journal-title":"Eur J Oncol Pharm."},{"key":"10.1016\/j.oftal.2020.04.018_bib0425","first-page":"231","article-title":"A pooled analysis to study trends in exposure to antineoplastic drugs among nurses","volume":"51","author":"Fransman","year":"2007","journal-title":"Ann Occup Hyg."},{"key":"10.1016\/j.oftal.2020.04.018_bib0430","year":"2014","journal-title":"Exposici\u00f3n a los carcin\u00f3genos y c\u00e1ncer relacionado con el trabajo: Una revisi\u00f3n de los m\u00e9todos de evaluaci\u00f3n"},{"key":"10.1016\/j.oftal.2020.04.018_bib0435","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1097\/JOM.0000000000000249","article-title":"Reproductive Health Risks Associated with Occupational Exposures to Antineoplastic Drugs in Health Care Settings: A Review of the Evidence","volume":"56","author":"Connor","year":"2014","journal-title":"J Occup Environ Med."},{"key":"10.1016\/j.oftal.2020.04.018_bib0440","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1093\/ajhp\/56.14.1427","article-title":"Surface contamination with antineoplastic agents in six cancer treatment centers in Canada and the United States","volume":"56","author":"Connor","year":"1999","journal-title":"Am J Health Syst Pharm."},{"key":"10.1016\/j.oftal.2020.04.018_bib0445","unstructured":"Diario Oficial de la Uni\u00f3n Europea L 158 de 30 de abril de 2004. Directiva 2004\/37\/CE del Parlamento Europeo y del Consejo de 29 de Abr de 2004 relativa a la protecci\u00f3n de los trabajadores contra los riesgos relacionados con la exposici\u00f3n a agentes carcin\u00f3genos o mut\u00e1genos durante el trabajo (sexta Directiva espec\u00edfica con arreglo al apartado 1 del art\u00edculo16 de la Directiva 89\/391\/CEE del Consejo). Disponible en: https:\/\/www.boe.es\/doue\/2004\/229\/L00023-00034.pdf"},{"key":"10.1016\/j.oftal.2020.04.018_bib0450","year":"2014","journal-title":"Gu\u00eda de buenas pr\u00e1cticas de preparaci\u00f3n de medicamentos en servicios de farmacia hospitalaria"},{"key":"10.1016\/j.oftal.2020.04.018_bib0455","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1177\/1078155213499387","article-title":"Cost savings realized by use of the PhaSeal (\u00ae) close-system transfer device for preparation of antineoplastic agents","author":"Edwards","year":"2013","journal-title":"J Oncol Pharm Pract."},{"key":"10.1016\/j.oftal.2020.04.018_bib0460","year":"2014","journal-title":"Riesgos para la salud y la seguridad en el sector sanitario: Gu\u00eda de prevenci\u00f3n y buenas pr\u00e1cticas"},{"key":"10.1016\/j.oftal.2020.04.018_bib0465","year":"2016","journal-title":"Preventing occupational exposure to cytotoxic and other hazardous drugs: European Policy Recommendations"},{"key":"10.1016\/j.oftal.2020.04.018_bib0470","unstructured":"The United States Pharmacopeial Convention (USP). Hazardous Drugs: Handling in Healthcare Settings USP39-NF 34 USP General Chapter 800, Section 5.2. 2016. Disponible en: https:\/\/www.usp.org\/news\/usp-publishes-standard-handling-hazardous-drugs-healthcare-settings"},{"key":"10.1016\/j.oftal.2020.04.018_bib0475","unstructured":"BOE. Real Decreto 665\/1997 de 12 de mayo, sobre la protecci\u00f3n de los trabajadores contra los riesgos relacionados con la exposici\u00f3n a agentes cancer\u00edgenos durante el trabajo. 1997. Disponible en: https:\/\/boe.es\/buscar\/pdf\/1997\/BOE-A-1997-11145-consolidado.pdf"},{"key":"10.1016\/j.oftal.2020.04.018_bib0480","unstructured":"BOE. Real Decreto 1124\/2000 de 16 de junio, por el que se modifica el Real Decreto 665\/1997 de 12 de mayo, sobre la protecci\u00f3n de los trabajadores contra los riesgos relacionados con la exposici\u00f3n a agentes carcin\u00f3genos durante el trabajo BOE 145. 2000. Disponible en: https:\/\/www.boe.es\/eli\/es\/rd\/2000\/06\/16\/1124"},{"key":"10.1016\/j.oftal.2020.04.018_bib0485","year":"2006","journal-title":"NTP 740: Exposici\u00f3n laboral a citost\u00e1ticos en el \u00e1mbito sanitario"},{"key":"10.1016\/j.oftal.2020.04.018_bib0490","year":"2015","journal-title":"NTP 1051 Exposici\u00f3n laboral a compuestos citost\u00e1ticos: sistemas seguros para su preparaci\u00f3n"},{"key":"10.1016\/j.oftal.2020.04.018_bib0495","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1472-6955-9-15","article-title":"Cancer incidence and adverse pregnancy outcome in registered nurses potentially exposed to antineoplastic drugs","volume":"9","author":"Ratner","year":"2010","journal-title":"BMC Nurs."},{"key":"10.1016\/j.oftal.2020.04.018_bib0500","year":"2014","journal-title":"Gu\u00eda de buenas pr\u00e1cticas para trabajadores profesionalmente expuestos a agentes citost\u00e1ticos"}],"container-title":["Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda"],"original-title":[],"language":"es","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0365669120301568?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0365669120301568?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,6]],"date-time":"2025-10-06T23:44:21Z","timestamp":1759794261000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0365669120301568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,7]]},"references-count":50,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7]]}},"alternative-id":["S0365669120301568"],"URL":"https:\/\/doi.org\/10.1016\/j.oftal.2020.04.018","relation":{},"ISSN":["0365-6691"],"issn-type":[{"value":"0365-6691","type":"print"}],"subject":[],"published":{"date-parts":[[2020,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Medidas para prevenir los riesgos asociados con la exposici\u00f3n a citost\u00e1ticos en cirug\u00eda filtrante de glaucoma","name":"articletitle","label":"Article Title"},{"value":"Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.oftal.2020.04.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Sociedad Espa\u00f1ola de Oftalmolog\u00eda. Published by Elsevier Espa\u00f1a, S.L.U. All rights reserved.","name":"copyright","label":"Copyright"}]}}