{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:55:40Z","timestamp":1790736940529,"version":"4.1.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda (English Edition)"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.oftale.2026.502617","type":"journal-article","created":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T06:19:31Z","timestamp":1785133171000},"page":"502617","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Efficacy and safety at 12 months of PRESERFLO\u00ae combined with DuraGen\u00ae and morphological evaluation using AS-OCT"],"prefix":"10.1016","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-9912-2326","authenticated-orcid":false,"given":"V.T.","family":"P\u00e9rez-Torregrosa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-9815-7026","authenticated-orcid":false,"given":"A.","family":"Caro-Ortega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"P\u00e9rez-Cant\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00c1.","family":"Ojeda-Parot","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"P\u00e9rez-Mart\u00ednez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Gracia-Rovira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-3141-5342","authenticated-orcid":false,"given":"M.","family":"Huerta-Morales","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Cabrera-Peset","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Duch-Samper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"Suppl 1","key":"10.1016\/j.oftale.2026.502617_bib0005","first-page":"1","article-title":"European Glaucoma Society: Terminology and guidelines for glaucoma, 6th Edition","volume":"109","year":"2025","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0010","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ogla.2021.07.008","article-title":"Safety and effectiveness of the PRESERFLO\u00ae MicroShunt in primary Open-angle glaucoma: results from a 2-year multicenter study","volume":"5","author":"Beckers","year":"2022","journal-title":"Ophthalmol Glaucoma"},{"key":"10.1016\/j.oftale.2026.502617_bib0015","doi-asserted-by":"crossref","first-page":"1104","DOI":"10.1136\/bjophthalmol-2021-320631","article-title":"One-year surgical outcomes of the PreserFlo MicroShunt in glaucoma: a multicentre analysis","volume":"107","author":"Tanner","year":"2023","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0020","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1097\/IJG.0000000000000368","article-title":"Three-year follow-up of a novel aqueous humor MicroShunt","volume":"25","author":"Batlle","year":"2016","journal-title":"J Glaucoma"},{"key":"10.1016\/j.oftale.2026.502617_bib0025","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0039-6257(87)90091-9","article-title":"Wound healing in glaucoma filtering surgery","volume":"32","author":"Skuta","year":"1987","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0030","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/00055735-200004000-00010","article-title":"Wound healing modulation after glaucoma surgery","volume":"11","author":"Cordeiro","year":"2000","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0035","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/IJG.0000000000001734","article-title":"Long-term results of the PRESERFLO MicroShunt in patients with primary open-angle glaucoma from a single-center nonrandomized study","volume":"30","author":"Batlle","year":"2021","journal-title":"J Glaucoma"},{"key":"10.1016\/j.oftale.2026.502617_bib0040","doi-asserted-by":"crossref","first-page":"1533","DOI":"10.1007\/s40123-025-01149-4","article-title":"Pooled analysis of three MicroShunt studies in primary open-angle glaucoma evaluating different concentrations of applied mitomycin C","volume":"14","author":"Garcia-Feijoo","year":"2025","journal-title":"Ophthalmol Ther"},{"key":"10.1016\/j.oftale.2026.502617_bib0045","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1111\/ceo.13799","article-title":"Efficacy of the Ologen collagen matrix in combination with the XEN gel stent implantation in the treatment of open-angle glaucoma: a case-control study","volume":"48","author":"Navero-Rodr\u00edguez","year":"2020","journal-title":"Clin Exp Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0050","doi-asserted-by":"crossref","first-page":"2861","DOI":"10.1097\/01.brs.0000148049.69541.ad","article-title":"Collagen matrix (DuraGen) in dural repair: analysis of a new modified technique","volume":"29","author":"Narotam","year":"2004","journal-title":"Spine (Phila Pa 1976)"},{"key":"10.1016\/j.oftale.2026.502617_bib0055","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-95489-7","article-title":"Histopathological analysis of duragen collagen matrix over time in humans","volume":"15","author":"Maeda","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.oftale.2026.502617_bib0060","series-title":"Cirug\u00eda de glaucoma con Preserflo\u00ae e interposici\u00f3n de DuraGen\u00ae en 15 ojos y su seguimiento a 3 meses. Comunicaci\u00f3n oral","author":"Ojeda Parot","year":"2024"},{"key":"10.1016\/j.oftale.2026.502617_bib0065","series-title":"Estudio de la eficacia hipotensora y de la seguridad del preserflo, MMC al 0,04% y con interposici\u00f3n de duragen, en la cirug\u00eda de Glaucoma del Hospital Cl\u00ednico de Valencia [Trabajo Fin de Grado no publicado]","author":"P\u00e9rez Cant\u00f3","year":"2025"},{"key":"10.1016\/j.oftale.2026.502617_bib0070","series-title":"Empleo de DuraGen\u00ae como modulador de la cicatrizaci\u00f3n en reintervenciones de cirug\u00edas de glauoma. Comunicaci\u00f3n oral","author":"Arruza Santos","year":"2025"},{"key":"10.1016\/j.oftale.2026.502617_bib0075","series-title":"Seguridad y tolerancia de la matriz de col\u00e1geno biodegradable DuraGen\u00ae como adyuvante en cirug\u00eda filtrante: estudio piloto a un a\u00f1o. Comunicaci\u00f3n oral","author":"Bold\u00fa Roig","year":"2025"},{"key":"10.1016\/j.oftale.2026.502617_bib0080","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1097\/IJG.0000000000002052","article-title":"Efficacy and safety of the preserflo microshunt with mitomycin C for the treatment of Open angle glaucoma","volume":"31","author":"Ibarz Barber\u00e1","year":"2022","journal-title":"J Glaucoma"},{"key":"10.1016\/j.oftale.2026.502617_bib0085","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1167\/tvst.12.11.4","article-title":"Factors correlated with mid-term morphology of functional blebs following implantation of Preserflo MicroShunt using AS-OCT","volume":"12","author":"Hasan","year":"2023","journal-title":"Transl Vis Sci Technol"},{"key":"10.1016\/j.oftale.2026.502617_bib0090","first-page":"e231","article-title":"Longitudinal bleb morphology in anterior segment OCT after minimally invasive transscleral ab interno Glaucoma Gel Microstent implantation","volume":"97","author":"Lenzhofer","year":"2019","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0095","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-95217-x","article-title":"Clinical outcomes of combined Preserflo Microshunt implantation and cataract surgery in open-angle glaucoma patients","volume":"11","author":"Mart\u00ednez-de-la-Casa","year":"2021","journal-title":"Sci Rep"},{"key":"10.1016\/j.oftale.2026.502617_bib0100","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.survophthal.2025.06.001","article-title":"Efficacy and complications of microcatheter-assisted minimally invasive glaucoma surgery for open-angle glaucoma: a systematic review and network meta-analysis","volume":"70","author":"Han","year":"2025","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0105","doi-asserted-by":"crossref","first-page":"417","DOI":"10.4103\/IJO.IJO_1502_23","article-title":"Preserflo TM MicroShunt implantation combined with Ologen TM in primary and secondary glaucoma patients in a clinical setting","volume":"72","author":"Rojo-Arnao","year":"2024","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0110","series-title":"Comparaci\u00f3n del uso de matriz celular Ologen versus Duragen en la esclerectom\u00eda profunda no perforante. Comunicaci\u00f3n oral","author":"Cobo de Nadal","year":"2025"},{"key":"10.1016\/j.oftale.2026.502617_bib0115","series-title":"Cirug\u00eda de glaucoma con Preserflo\u00ae, Mitomicina C al 0,04% y DuraGen\u00ae: resultados a los 6 meses. Comunicaci\u00f3n oral","author":"P\u00e9rez Mart\u00ednez","year":"2025"},{"key":"10.1016\/j.oftale.2026.502617_bib0120","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/s40662-021-00253-3","article-title":"Preliminary results of Preserflo Microshunt versus Preserflo Microshunt and Ologen implantation","volume":"8","author":"Vastardis","year":"2021","journal-title":"Eye Vis (Lond)"},{"key":"10.1016\/j.oftale.2026.502617_bib0125","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.oftal.2024.05.015","article-title":"Anterior segment optic coherence tomography (OCT-SA) findings in glaucoma surgery after Preserflo\u00ae Microshunt implantation","volume":"99","author":"Ortega-Prades","year":"2024","journal-title":"Arch Soc Esp Oftalmol (Engl Ed)"},{"key":"10.1016\/j.oftale.2026.502617_bib0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0286884","article-title":"Bleb geometry and morphology after Preserflo Microshunt surgery: risk factors for surgical failure","volume":"18","author":"Ibarz Barber\u00e1","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.oftale.2026.502617_bib0135","doi-asserted-by":"crossref","first-page":"e192","DOI":"10.1111\/aos.14863","article-title":"Anterior-segment optical coherence tomography of filtering blebs in the early postoperative period of ab externo SIBS microshunt implantation with mitomycin C: morphological analysis and correlation with intraocular pressure reduction","volume":"100","author":"Ibarz Barber\u00e1","year":"2022","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.oftale.2026.502617_bib0140","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/610623","article-title":"Anterior segment optical coherence tomography imaging of conjunctival filtering blebs after glaucoma surgery","volume":"2014","author":"Mastropasqua","year":"2014","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.oftale.2026.502617_bib0145","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.oftal.2023.06.006","article-title":"Obstruction of the Preserflo Microshunt implant due to incomplete exit to the anterior chamber: case report","volume":"98","author":"Ortega-Prades","year":"2023","journal-title":"Arch Soc Esp Oftalmol (Engl Ed)"},{"key":"10.1016\/j.oftale.2026.502617_bib0150","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/IJG.0000000000002096","article-title":"Novel Bleb classification following ab interno implantation of gel-stent using anterior segment optical coherence tomography","volume":"32","author":"Hasan","year":"2023","journal-title":"J Glaucoma"}],"container-title":["Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda (English Edition)"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173579426001842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2173579426001842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T02:21:58Z","timestamp":1790734918000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2173579426001842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":30,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["S2173579426001842"],"URL":"https:\/\/doi.org\/10.1016\/j.oftale.2026.502617","relation":{},"ISSN":["2173-5794"],"issn-type":[{"value":"2173-5794","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Efficacy and safety at 12 months of PRESERFLO\u00ae combined with DuraGen\u00ae and morphological evaluation using AS-OCT","name":"articletitle","label":"Article Title"},{"value":"Archivos de la Sociedad Espa\u00f1ola de Oftalmolog\u00eda (English Edition)","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.oftale.2026.502617","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"https:\/\/doi.org\/10.1016\/j.oftal.2026.502617","name":"associatedlink","label":"CrossRef DOI link to the associated document"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Espa\u00f1a, S.L.U. on behalf of Sociedad Espa\u00f1ola de Oftalmolog\u00eda. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"502617"}}