{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T04:12:50Z","timestamp":1746245570155,"version":"3.40.4"},"reference-count":68,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","theclinics.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Obstetrics and Gynecology Clinics of North America"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.ogc.2024.12.003","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T21:13:05Z","timestamp":1737666785000},"page":"269-288","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Individualizing Management of Pregnancy of Unknown Location and Uncertain Prognosis"],"prefix":"10.1016","volume":"52","author":[{"given":"Cassandra L.","family":"Denefrio","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel","family":"Flink-Bochacki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.ogc.2024.12.003_bib1","first-page":"163","article-title":"Pregnancy of unknown location","volume":"68","author":"Schuneman","year":"2015","journal-title":"S\u00a0D Med"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib2","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/j.fertnstert.2010.09.006","article-title":"Pregnancy of unknown location: a consensus statement of nomenclature, definitions, and outcome","volume":"95","author":"Barnhart","year":"2011","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ogc.2024.12.003_bib3","first-page":"1","article-title":"Conventional and modern markers of pregnancy of unknown location: update and narrative review","volume":"00","author":"Hou","year":"2024","journal-title":"Int J Gynecol Obstet"},{"key":"10.1016\/j.ogc.2024.12.003_bib4","doi-asserted-by":"crossref","DOI":"10.6061\/clinics\/2019\/e1111","article-title":"Pregnancy of unknown location","volume":"74","author":"Pereira","year":"2019","journal-title":"Clinics"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib5","doi-asserted-by":"crossref","first-page":"e91","DOI":"10.1097\/AOG.0000000000002560","article-title":"ACOG practice bulletin No. 193: tubal ectopic pregnancy","volume":"131","author":"Barnhart","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ogc.2024.12.003_bib6","doi-asserted-by":"crossref","DOI":"10.1148\/radiol.240122","article-title":"A\u00a0lexicon for first-trimester US: society of Radiologists in ultrasound consensus conference recommendations","volume":"312","author":"Rodgers","year":"2024","journal-title":"Radiology"},{"issue":"6","key":"10.1016\/j.ogc.2024.12.003_bib7","first-page":"E20","article-title":"AIUM practice parameter for the performance of standard diagnostic obstetric ultrasound","volume":"43","year":"2024","journal-title":"J\u00a0Ultrasound Med"},{"key":"10.1016\/j.ogc.2024.12.003_bib8","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1093\/oxfordjournals.humrep.a136123","article-title":"The expectant management of early pregnancies of uncertain site","volume":"10","author":"Hahlin","year":"1995","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ogc.2024.12.003_bib9","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1046\/j.1469-0705.1999.14040231.x","article-title":"The expectant management of women with pregnancies of unknown location","volume":"14","author":"Banerjee","year":"1999","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ogc.2024.12.003_bib10","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1111\/j.1471-0528.1988.tb12804.x","article-title":"Suspected ectopic pregnancy: ultrasound findings and hCG levels assessed by an immunofluorometric assay","volume":"95","author":"Cacciatore","year":"1988","journal-title":"Br J Obstet Gynaecol"},{"key":"10.1016\/j.ogc.2024.12.003_bib11","first-page":"158","article-title":"Expectant management of early pregnancies of unknown location: a prospective evaluation of methods to predict spontaneous resolution of pregnancy","volume":"108","author":"Banerjee","year":"2001","journal-title":"BJOG"},{"key":"10.1016\/j.ogc.2024.12.003_bib12","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.ijgo.2004.04.004","article-title":"Human chorionic gonadotrophin and progesterone levels for the investigation of pregnancies of unknown location","volume":"86","author":"Condous","year":"2004","journal-title":"Int J Gynaecol Obstet"},{"key":"10.1016\/j.ogc.2024.12.003_bib13","first-page":"258","article-title":"Suspected ectopic pregnancy: expectant management in patients with negative sonographic findings and low serum hCG concentrations","volume":"1","author":"Hajenius","year":"1995","journal-title":"Early Pregnancy"},{"key":"10.1016\/j.ogc.2024.12.003_bib14","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/S0015-0282(98)00278-7","article-title":"Serum human chorionic gonadotropin measurement in the diagnosis of ectopic pregnancy when transvaginal sonography is inconclusive","volume":"70","author":"Mol","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ogc.2024.12.003_bib15","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1093\/oxfordjournals.humrep.a138247","article-title":"Transvaginal sonography and human chorionic gonadotrophin measurements in suspected ectopic pregnancy: a detailed analysis of a diagnostic approach","volume":"8","author":"Ankum","year":"1993","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ogc.2024.12.003_bib16","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1093\/oxfordjournals.humrep.a138246","article-title":"Laparoscopy: a dispensable tool in the diagnosis of ectopic pregnancy?","volume":"8","author":"Ankum","year":"1993","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ogc.2024.12.003_bib17","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1067\/mem.2002.122432","article-title":"Subclassification of indeterminate pelvic ultrasonography: prospective evaluation of the risk of ectopic pregnancy","volume":"39","author":"Dart","year":"2002","journal-title":"Ann Emerg Med"},{"key":"10.1016\/j.ogc.2024.12.003_bib18","doi-asserted-by":"crossref","first-page":"770","DOI":"10.1002\/uog.2636","article-title":"Diagnostic accuracy of varying discriminatory zones for the prediction of ectopic pregnancy in women with a pregnancy of unknown location","volume":"26","author":"Condous","year":"2005","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.ogc.2024.12.003_bib19","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.jogc.2021.01.002","article-title":"Guideline No. 414: management of pregnancy of unknown location and tubal and nontubal ectopic pregnancies","volume":"43","author":"Po","year":"2021","journal-title":"J\u00a0Obstet Gynaecol Can"},{"key":"10.1016\/j.ogc.2024.12.003_bib20","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/humupd\/dmt047","article-title":"Diagnosing ectopic pregnancy and current concepts in the management of pregnancy of unknown location","volume":"20","author":"Kirk","year":"2014","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ogc.2024.12.003_bib21","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/j.1471-0528.2011.02893.x","article-title":"Introduction of a single visit protocol in the management of selected patients with pregnancy of unknown location: a prospective study","volume":"118","author":"Cordina","year":"2011","journal-title":"BJOG"},{"issue":"6","key":"10.1016\/j.ogc.2024.12.003_bib22","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1097\/01.gco.0000191515.07019.cb","article-title":"Pregnancies of unknown location: diagnostic dilemmas and management","volume":"17","author":"Condous","year":"2005","journal-title":"Curr Opin Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ogc.2024.12.003_bib23","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/uog.2838","article-title":"Pregnancies of unknown location: consensus statement","volume":"28","author":"Condous","year":"2006","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"55","key":"10.1016\/j.ogc.2024.12.003_bib24","article-title":"Effect of clinical setting on prevalence of pregnancy of unknown location: a retrospective cohort study","volume":"141","author":"Javlekar","year":"2023","journal-title":"Obstet Gynecol"},{"key":"10.1016\/j.ogc.2024.12.003_bib25","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/uog.9007","article-title":"A\u00a0model and scoring system to predict outcome of intrauterine pregnancies of uncertain viability","volume":"37","author":"Bottomley","year":"2011","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"15","key":"10.1016\/j.ogc.2024.12.003_bib26","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1056\/NEJMra1302417","article-title":"Diagnostic criteria for nonviable pregnancy early in the first trimester","volume":"369","author":"Doubilet","year":"2013","journal-title":"N\u00a0Engl J Med"},{"issue":"5","key":"10.1016\/j.ogc.2024.12.003_bib27","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.fertnstert.2012.09.018","article-title":"Early pregnancy failure: beware of the pitfalls of modern management","volume":"98","author":"Barnhart","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ogc.2024.12.003_bib28","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.fertnstert.2012.09.032","article-title":"Is there a need to definitively diagnose the location of a pregnancy of unknown location? The case for \u201cno\u201d","volume":"98","author":"Reid","year":"2012","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1016\/j.ogc.2024.12.003_bib29","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/01.AOG.0000128174.48843.12","article-title":"Symptomatic patients with an early viable intrauterine pregnancy: HCG curves redefined","volume":"104","author":"Barnhart","year":"2004","journal-title":"Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib30","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1097\/AOG.0000000000001568","article-title":"Differences in serum human chorionic gonadotropin rise in early pregnancy by race and value at presentation","volume":"128","author":"Barnhart","year":"2016","journal-title":"Obstet Gynaecol"},{"issue":"5 Pt 1","key":"10.1016\/j.ogc.2024.12.003_bib31","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1097\/01.AOG.0000142712.80407.fd","article-title":"Decline of serum human chorionic gonadotropin and spontaneous complete abortion: defining the normal curve","volume":"104","author":"Barnhart","year":"2004","journal-title":"Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.ogc.2024.12.003_bib32","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1016\/j.fertnstert.2012.06.026","article-title":"How and when human chorionic gonadotropin curves in women with an ectopic pregnancy mimic other outcomes: differences by race and ethnicity","volume":"98","author":"Dillon","year":"2012","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ogc.2024.12.003_bib33","doi-asserted-by":"crossref","first-page":"1900","DOI":"10.1093\/humrep\/deh341","article-title":"The use of a new logistic regression model for predicting the outcome of pregnancies of unknown location","volume":"19","author":"Condous","year":"2004","journal-title":"Hum Reprod"},{"issue":"5","key":"10.1016\/j.ogc.2024.12.003_bib34","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/j.1471-0528.2006.00924.x","article-title":"Failing pregnancies of unknown location: a prospective evaluation of the human chorionic gonadotrophin ratio","volume":"113","author":"Condous","year":"2006","journal-title":"BJOG"},{"issue":"6","key":"10.1016\/j.ogc.2024.12.003_bib35","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1002\/uog.4015","article-title":"Prediction of ectopic pregnancy in women with a pregnancy of unknown location","volume":"29","author":"Condous","year":"2007","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"10","key":"10.1016\/j.ogc.2024.12.003_bib36","doi-asserted-by":"crossref","first-page":"2434","DOI":"10.1093\/humrep\/deq217","article-title":"Does a prediction model for pregnancy of unknown location developed in the UK validate on a US population?","volume":"25","author":"Barnhart","year":"2010","journal-title":"Hum Reprod"},{"key":"10.1016\/j.ogc.2024.12.003_bib37","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1002\/uog.15864","article-title":"Managing pregnancy of unknown location based on initial serum progesterone and serial serum hCG levels: development and validation of a two-step triage protocol","volume":"48","author":"Van Calster","year":"2016","journal-title":"Ultrasound Obstet Gynecol"},{"key":"10.1016\/j.ogc.2024.12.003_bib38","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/uog.20420","article-title":"Triaging women with pregnancy of unknown location using two-step protocol including M6 model: clinical implementation study","volume":"55","author":"Bobdiwala","year":"2020","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib39","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/1471-0528.16497","article-title":"External validation of models to predict the outcome of pregnancies of unknown location: a multicentre cohort study","volume":"128","author":"Christodoulou","year":"2021","journal-title":"BJOG"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib40","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1002\/uog.27515","article-title":"Updating M6 pregnancy of unknown location risk-prediction model including evaluation of clinical factors","volume":"63","author":"Kyriacou","year":"2024","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib41","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1093\/humrep\/det450","article-title":"Ectopic pregnancy prediction in women with a pregnancy of unknown location: data beyond 48\u00a0h are necessary","volume":"29","author":"Zee","year":"2014","journal-title":"Hum Reprod"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib42","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1002\/jum.15430","article-title":"First-trimester prognosis when an early gestational sac is seen on ultrasound imaging: logistic regression prediction model","volume":"40","author":"Doubilet","year":"2021","journal-title":"J\u00a0Ultrasound Med"},{"key":"10.1016\/j.ogc.2024.12.003_bib43","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ejogrb.2017.11.020","article-title":"Serial hCG and progesterone levels to predict early pregnancy outcomes in pregnancies of uncertain viability: a prospective study","volume":"220","author":"Puget","year":"2018","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"issue":"5","key":"10.1016\/j.ogc.2024.12.003_bib44","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1097\/AOG.0000000000004124","article-title":"Prioritizing desiredness in pregnancy of unknown location: an algorithm for patient-centered care","volume":"136","author":"Flynn","year":"2020","journal-title":"Obstet Gynecol"},{"issue":"6","key":"10.1016\/j.ogc.2024.12.003_bib45","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1093\/humrep\/dem073","article-title":"Rationalizing the follow-up of pregnancies of unknown location","volume":"22","author":"Kirk","year":"2007","journal-title":"Hum Reprod"},{"issue":"4","key":"10.1016\/j.ogc.2024.12.003_bib46","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/uog.236","article-title":"The conservative management of early pregnancy complications: a review of the literature","volume":"22","author":"Condous","year":"2003","journal-title":"Ultrasound Obstet Gynecol"},{"issue":"5","key":"10.1016\/j.ogc.2024.12.003_bib47","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1097\/AOG.0000000000004756","article-title":"Mifepristone and misoprostol for undesired pregnancy of unknown location","volume":"139","author":"Goldberg","year":"2022","journal-title":"Obstet Gynecol"},{"issue":"2","key":"10.1016\/j.ogc.2024.12.003_bib48","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1136\/bmjsrh-2022-201677","article-title":"Very early medical abortion: treatment with mifepristone and misoprostol before ultrasonographic visualisation of an intrauterine pregnancy","volume":"49","author":"Tai","year":"2023","journal-title":"BMJ Sex Reprod Health"},{"key":"10.1016\/j.ogc.2024.12.003_bib49","doi-asserted-by":"crossref","DOI":"10.1016\/j.contraception.2023.110343","article-title":"hCG trends after mifepristone and misoprostol for undesired pregnancy of unknown location","volume":"131","author":"Bharadwa","year":"2024","journal-title":"Contraception"},{"key":"10.1016\/j.ogc.2024.12.003_bib50","first-page":"813","article-title":"Comparison of abortions induced by methotrexate or mifepristone followed by misoprostol","volume":"99","author":"Wiebe","year":"2002","journal-title":"Obstet Gynecol"},{"issue":"1","key":"10.1016\/j.ogc.2024.12.003_bib51","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0010-7824(98)00146-2","article-title":"Comparing abortion induced with methotrexate and misoprostol to methotrexate alone","volume":"59","author":"Wiebe","year":"1999","journal-title":"Contraception"},{"issue":"1","key":"10.1016\/j.ogc.2024.12.003_bib52","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.ijgo.2009.04.015","article-title":"Methotrexate with or without misoprostol to terminate pregnancies with no gestational sac visible by ultrasound","volume":"107","author":"Wiebe","year":"2009","journal-title":"Int J Gynaecol Obstet"},{"issue":"2","key":"10.1016\/j.ogc.2024.12.003_bib53","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1067\/mob.2002.123898","article-title":"Early surgical abortion: efficacy and safety","volume":"187","author":"Paul","year":"2002","journal-title":"Am J Obstet Gynecol"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib54","first-page":"225","article-title":"Is the endometrial suction curette useful in the detection of chorionic villi during the first trimester?","volume":"3","author":"Hock","year":"1997","journal-title":"Early Pregnancy"},{"year":"2001","series-title":"Crossing the quality chasm: a new health system for the 21st century","author":"Gerteis","key":"10.1016\/j.ogc.2024.12.003_bib55"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib56","first-page":"2","article-title":"What patients really want","volume":"15","author":"Gerteis","year":"1993","journal-title":"Health Manag Q."},{"issue":"1","key":"10.1016\/j.ogc.2024.12.003_bib57","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1093\/humupd\/dmx030","article-title":"Patient-centered early pregnancy care: a systematic review of quantitative and qualitative studies on the perspectives of women and their partners","volume":"24","author":"Van den Berg","year":"2018","journal-title":"Hum Reprod Update"},{"key":"10.1016\/j.ogc.2024.12.003_bib58","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1111\/jmwh.12526","article-title":"Key concepts in pregnancy of unknown location: identifying ectopic pregnancy and providing patient-centered care","volume":"62","author":"Fields","year":"2017","journal-title":"J\u00a0Midwifery Wom Health"},{"key":"10.1016\/j.ogc.2024.12.003_bib59","doi-asserted-by":"crossref","DOI":"10.1016\/j.contraception.2024.110448","article-title":"Do miscarriage care practice recommendations align with individuals\u2019 needs?: a scoping review","volume":"136","author":"Filippa","year":"2024","journal-title":"Contraception"},{"issue":"3","key":"10.1016\/j.ogc.2024.12.003_bib60","first-page":"246","article-title":"Patient attitudes and preferences for the management of pregnancy of unknown location","volume":"3","author":"Wu","year":"2022","journal-title":"F\u00a0S Rep"},{"issue":"5","key":"10.1016\/j.ogc.2024.12.003_bib61","doi-asserted-by":"crossref","first-page":"e197","DOI":"10.1097\/AOG.0000000000002899","article-title":"Ko practice bulletin No. 200: early pregnancy loss","volume":"132","year":"2018","journal-title":"Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.ogc.2024.12.003_bib62","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1177\/1077558712465774","article-title":"Patient-centered care and outcomes: a systematic review of the literature","volume":"70","author":"Rathert","year":"2013","journal-title":"Med Care Res Rev"},{"issue":"2","key":"10.1016\/j.ogc.2024.12.003_bib63","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.contraception.2021.04.015","article-title":"Early pregnancy care in North America: a proposal to high-value care that can level health disparities","volume":"104","author":"Shorter","year":"2021","journal-title":"Contraception"},{"issue":"1","key":"10.1016\/j.ogc.2024.12.003_bib64","doi-asserted-by":"crossref","first-page":"41.e1","DOI":"10.1016\/j.ajog.2023.03.038","article-title":"The association between abortion restrictions and patient-centered care for early pregnancy loss at US obstetrics-gynecology residency programs","volume":"229","author":"Phillips","year":"2023","journal-title":"Am J Obstet Gynecol"},{"issue":"4","key":"10.1016\/j.ogc.2024.12.003_bib65","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/S0015-0282(16)56638-2","article-title":"Serum human chorionic gonadotropin dynamics during spontaneous resolution of ectopic pregnancy","volume":"61","author":"Korhonen","year":"1994","journal-title":"Fertil Steril"},{"key":"10.1016\/j.ogc.2024.12.003_bib66","doi-asserted-by":"crossref","DOI":"10.1016\/j.contraception.2023.110132","article-title":"Effectiveness and safety of misoprostol-only for first-trimester medication abortion: an updated systematic review and meta-analysis","volume":"127","author":"Raymond","year":"2023","journal-title":"Contraception"},{"issue":"4","key":"10.1016\/j.ogc.2024.12.003_bib67","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/j.fertnstert.2003.08.041","article-title":"Hormone pattern after misoprostol administration for a nonviable first-trimester gestation","volume":"81","author":"Barnhart","year":"2004","journal-title":"Fertil Steril"},{"issue":"6","key":"10.1016\/j.ogc.2024.12.003_bib68","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0010-7824(99)00047-5","article-title":"Methotrexate and misoprostol used alone or in combination for early abortion","volume":"59","author":"Ozeren","year":"1999","journal-title":"Contraception"}],"container-title":["Obstetrics and Gynecology Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889854524000986?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0889854524000986?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T22:50:57Z","timestamp":1746226257000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0889854524000986"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":68,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0889854524000986"],"URL":"https:\/\/doi.org\/10.1016\/j.ogc.2024.12.003","relation":{},"ISSN":["0889-8545"],"issn-type":[{"type":"print","value":"0889-8545"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Individualizing Management of Pregnancy of Unknown Location and Uncertain Prognosis","name":"articletitle","label":"Article Title"},{"value":"Obstetrics and Gynecology Clinics of North America","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ogc.2024.12.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}