{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T09:54:23Z","timestamp":1791453263231,"version":"4.3.3"},"reference-count":39,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,7,1]],"date-time":"2018-07-01T00:00:00Z","timestamp":1530403200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology Glaucoma"],"published-print":{"date-parts":[[2018,7]]},"DOI":"10.1016\/j.ogla.2018.06.003","type":"journal-article","created":{"date-parts":[[2018,7,6]],"date-time":"2018-07-06T07:18:38Z","timestamp":1530861518000},"page":"66-74","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Treatment Outcomes of Mitomycin C-Augmented Trabeculectomy, Sub-Tenon Injection versus Soaked Sponges, after 3 Years of Follow-up"],"prefix":"10.1016","volume":"1","author":[{"given":"Hamed","family":"Esfandiari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Pakravan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahin","family":"Yazdani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azadeh","family":"Doozandeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehdi","family":"Yaseri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian P.","family":"Conner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ogla.2018.06.003_bib1","doi-asserted-by":"crossref","first-page":"2491","DOI":"10.1167\/iovs.12-9483l","article-title":"Advances in glaucoma treatment and management: surgery","volume":"53","author":"Coleman","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ogla.2018.06.003_bib2","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.ophtha.2007.10.023","article-title":"Needling revision of trabeculectomies bleb morphology and long-term survival","volume":"115","author":"Rotchford","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ogla.2018.06.003_bib3","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD002897.pub2","article-title":"Intra-operative mitomycin C for glaucoma surgery","author":"Wilkins","year":"2005","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ogla.2018.06.003_bib4","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1159\/000458483","article-title":"Enhanced trabeculectomy: the Moorfields Safer Surgery System","volume":"59","author":"Khaw","year":"2017","journal-title":"Dev Ophthalmol"},{"issue":"Suppl 1","key":"10.1016\/j.ogla.2018.06.003_bib5","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1186\/s12886-015-0134-8","article-title":"Pathobiology of wound healing after glaucoma filtration surgery","volume":"15","author":"Yamanaka","year":"2015","journal-title":"BMC Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib6","first-page":"81","article-title":"Does titration of mitomycin C as an adjunct to trabeculectomy significantly influence the intraocular pressure outcome?","volume":"3","author":"Lee","year":"2009","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib7","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.ophtha.2003.04.005","article-title":"Factors associated with success in first-time trabeculectomy for patients at low risk of failure with chronic open-angle glaucoma","volume":"111","author":"Edmunds","year":"2004","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ogla.2018.06.003_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD006259.pub2","article-title":"Mitomycin C versus 5-fluorouracil for wound healing in glaucoma surgery","author":"Cabourne","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.ogla.2018.06.003_bib9","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1136\/bjophthalmol-2016-309671","article-title":"Mitomycin C-augmented trabeculectomy: subtenon injection versus soaked sponges: a randomised clinical trial","volume":"101","author":"Pakravan","year":"2017","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib10","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1097\/00061198-200306000-00015","article-title":"Morphologic classification of filtering blebs after glaucoma filtration surgery: the Indiana Bleb Appearance Grading Scale","volume":"12","author":"Cantor","year":"2003","journal-title":"J\u00a0Glaucoma"},{"key":"10.1016\/j.ogla.2018.06.003_bib11","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.ophtha.2008.08.009","article-title":"Long-term outcomes of intraoperative 5-fluorouracil versus intraoperative mitomycin C in primary trabeculectomy surgery","volume":"116","author":"Palanca-Capistrano","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ogla.2018.06.003_bib12","doi-asserted-by":"crossref","first-page":"491","DOI":"10.2147\/OPTH.S17328","article-title":"Augmenting trabeculectomy in glaucoma with subconjunctival mitomycin C versus subconjunctival 5-fluorouracil: a randomized clinical trial","volume":"5","author":"Mostafaei","year":"2011","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib13","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.ajo.2011.10.026","article-title":"Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up","volume":"153","author":"Gedde","year":"2012","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib14","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1097\/IJG.0000000000000219","article-title":"Targeting a low-teen intraocular pressure by trabeculectomy with a fornix-based conjunctival flap: continuous Japanese case series by a single surgeon","volume":"24","author":"Aoyama","year":"2015","journal-title":"J\u00a0Glaucoma"},{"key":"10.1016\/j.ogla.2018.06.003_bib15","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1097\/IJG.0000000000000775","article-title":"Primary trabeculectomy outcomes by glaucoma fellows in a tertiary hospital in Brazil","volume":"26","author":"Abe","year":"2017","journal-title":"J\u00a0Glaucoma"},{"key":"10.1016\/j.ogla.2018.06.003_bib16","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0002-9394(14)73529-9","article-title":"Three-year follow-up of the Fluorouracil Filtering Surgery Study","volume":"115","year":"1993","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib17","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ajo.2006.07.020","article-title":"Treatment outcomes in the tube versus trabeculectomy study after one year of follow-up","volume":"143","author":"Gedde","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib18","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1136\/bjo.85.6.686","article-title":"Long term results and complications of trabeculectomy augmented with low dose mitomycin C in patients at risk for filtration failure","volume":"85","author":"Casson","year":"2001","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"10.1016\/j.ogla.2018.06.003_bib19","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1034\/j.1600-0420.2002.800307.x","article-title":"Long-term outcome of trabeculectomy in terms of intraocular pressure","volume":"80","author":"Ehrnrooth","year":"2002","journal-title":"Acta Ophthalmol Scand"},{"key":"10.1016\/j.ogla.2018.06.003_bib20","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/S0039-6257(03)00038-9","article-title":"Antifibrotics and wound healing in glaucoma surgery","volume":"48","author":"Lama","year":"2003","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib21","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.ajo.2011.10.024","article-title":"Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up","volume":"153","author":"Gedde","year":"2012","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib22","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/01.icu.0000156138.05323.6f","article-title":"Recent advances in trabeculectomy technique","volume":"16","author":"Jones","year":"2005","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib23","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1016\/S0161-6420(00)00391-2","article-title":"Trabeculectomy with intraoperative mitomycin C versus 5-fluorouracil. Prospective randomized clinical trial","volume":"107","author":"Singh","year":"2000","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ogla.2018.06.003_bib24","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1001\/archopht.1997.01100160139001","article-title":"A\u00a0long-term dose-response study of mitomycin in glaucoma filtration surgery","volume":"115","author":"Robin","year":"1997","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib25","series-title":"Glaucoma Surgery. Vol 50. Developments in Ophthalmology","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000334776","article-title":"Enhanced trabeculectomy\u2014the Moorfields Safer Surgery System","author":"Khaw","year":"2012"},{"key":"10.1016\/j.ogla.2018.06.003_bib26","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1097\/ICU.0000000000000236","article-title":"Innovations and adaptations in trabeculectomy","volume":"27","author":"Sawchyn","year":"2016","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib27","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1097\/00061198-200110001-00029","article-title":"Advances in glaucoma surgery: evolution of antimetabolite adjunctive therapy","volume":"10","author":"Khaw","year":"2001","journal-title":"J\u00a0Glaucoma"},{"key":"10.1016\/j.ogla.2018.06.003_bib28","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0002-9394(14)72853-3","article-title":"Retained cellulose sponge after trabeculectomy with adjunctive subconjunctival mitomycin C","volume":"118","author":"Shin","year":"1994","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib29","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1089\/jop.1995.11.233","article-title":"Preoperative mitomycin-C subconjunctival injection and glaucoma filtering surgery","volume":"11","author":"Hung","year":"1995","journal-title":"J\u00a0Ocul Pharmacol Ther"},{"key":"10.1016\/j.ogla.2018.06.003_bib30","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1111\/j.1755-3768.2007.01147.x","article-title":"Trabeculectomy surgery augmented with intra-Tenon injection of mitomycin C","volume":"86","author":"Lee","year":"2008","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.ogla.2018.06.003_bib31","unstructured":"Lim MC, Tong MG, Brandt JD. A comparison of trabeculectomy surgery outcomes with mitomycin-C applied by intra-tenon injection versus sponge method. Abstract. American Glaucoma Society 23rd Annual Meeting 2013."},{"key":"10.1016\/j.ogla.2018.06.003_bib32","doi-asserted-by":"crossref","DOI":"10.12688\/f1000research.12904.1","article-title":"Predictive value of early postoperative IOP and bleb morphology in mitomycin-C augmented trabeculectomy","volume":"6","author":"Esfandiari","year":"2017","journal-title":"F1000Res"},{"key":"10.1016\/j.ogla.2018.06.003_bib33","first-page":"249","article-title":"Filtering blebs: follow up of trabeculectomy","volume":"24","author":"Vesti","year":"1993","journal-title":"Ophthalmic Surg"},{"key":"10.1016\/j.ogla.2018.06.003_bib34","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1089\/jop.1998.14.491","article-title":"A\u00a0novel method for controlling the quantity of mitomycin-C applied during filtering surgery for glaucoma","volume":"14","author":"Mehel","year":"1998","journal-title":"J\u00a0Ocul Pharmacol Ther"},{"key":"10.1016\/j.ogla.2018.06.003_bib35","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1076\/ceyr.25.4.221.13485","article-title":"Impact of irrigation in a new model for in\u00a0vitro diffusion of mitomycin-C after episcleral application","volume":"25","author":"Georgopoulos","year":"2002","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.ogla.2018.06.003_bib36","series-title":"Ophthalmology: A Practical Textbook","first-page":"1596","article-title":"Modulating scarring and new surgical techniques in glaucoma surgery","author":"Khaw","year":"2003"},{"key":"10.1016\/j.ogla.2018.06.003_bib37","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3928\/1542-8877-19960801-04","article-title":"Subconjunctival versus intrascleral mitomycin-C in trabeculectomy","volume":"27","author":"Tressler","year":"1996","journal-title":"Ophthalmic Surg Lasers"},{"key":"10.1016\/j.ogla.2018.06.003_bib38","doi-asserted-by":"crossref","first-page":"714","DOI":"10.3928\/1542-8877-19980901-04","article-title":"Episcleral versus combined episcleral and intrascleral application of mitomycin-C in trabeculectomy","volume":"29","author":"Vass","year":"1998","journal-title":"Ophthalmic Surg Lasers"},{"key":"10.1016\/j.ogla.2018.06.003_bib39","first-page":"91","article-title":"Assessing the role of subconjunctival versus intrascleral application of mitomycin C in high-risk trabeculectomies","volume":"49","author":"Agarwal","year":"2001","journal-title":"Indian J Ophthalmol"}],"container-title":["Ophthalmology Glaucoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589419618300292?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589419618300292?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T18:50:24Z","timestamp":1762887024000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589419618300292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["S2589419618300292"],"URL":"https:\/\/doi.org\/10.1016\/j.ogla.2018.06.003","relation":{},"ISSN":["2589-4196"],"issn-type":[{"value":"2589-4196","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment Outcomes of Mitomycin C-Augmented Trabeculectomy, Sub-Tenon Injection versus Soaked Sponges, after 3 Years of Follow-up","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology Glaucoma","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ogla.2018.06.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 by the American Academy of Ophthalmology","name":"copyright","label":"Copyright"}]}}