{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:18:41Z","timestamp":1788412721206,"version":"build-2803163510"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,3,1]],"date-time":"2022-03-01T00:00:00Z","timestamp":1646092800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T00:00:00Z","timestamp":1630886400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007819","name":"Allergan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006692","name":"Universit\u00e0 degli Studi di Torino","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006692","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006483","name":"AbbVie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006483","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology Glaucoma"],"published-print":{"date-parts":[[2022,3]]},"DOI":"10.1016\/j.ogla.2021.08.005","type":"journal-article","created":{"date-parts":[[2021,8,31]],"date-time":"2021-08-31T12:50:28Z","timestamp":1630414228000},"page":"210-218","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":66,"title":["Effectiveness of MicroShunt in Patients with Primary Open-Angle and Pseudoexfoliative Glaucoma"],"prefix":"10.1016","volume":"5","author":[{"given":"Antonio Maria","family":"Fea","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Luca","family":"Laffi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Martini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario A.","family":"Economou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7153-1074","authenticated-orcid":false,"given":"Paolo","family":"Caselgrandi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6399-3140","authenticated-orcid":false,"given":"Matteo","family":"Sacchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leon","family":"Au","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ogla.2021.08.005_bib1","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1136\/bjo.2005.081224","article-title":"The number of people with glaucoma worldwide in 2010 and 2020","volume":"90","author":"Quigley","year":"2006","journal-title":"Br J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ogla.2021.08.005_bib2","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.ophtha.2007.04.050","article-title":"Glaucoma and quality of life: the Salisbury Eye Evaluation","volume":"115","author":"Freeman","year":"2008","journal-title":"Ophthalmology"},{"issue":"11","key":"10.1016\/j.ogla.2021.08.005_bib3","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1016\/j.ophtha.2014.05.013","article-title":"Global prevalence of glaucoma and projections of glaucoma burden through 2040: a systematic review and meta-analysis","volume":"121","author":"Tham","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ogla.2021.08.005_bib4","first-page":"523","article-title":"Different strategies and cost-effectiveness in the treatment of primary open angle glaucoma","volume":"6","author":"Ting","year":"2014","journal-title":"Clinicoecon Outcomes Res"},{"issue":"4","key":"10.1016\/j.ogla.2021.08.005_bib5","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.ophtha.2011.09.043","article-title":"A\u00a0twenty-year follow-up study of trabeculectomy: risk factors and outcomes","volume":"119","author":"Landers","year":"2012","journal-title":"Ophthalmology"},{"issue":"1","key":"10.1016\/j.ogla.2021.08.005_bib6","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.ajo.2005.02.013","article-title":"Perioperative complications of trabeculectomy in the collaborative initial glaucoma treatment study (CIGTS)","volume":"140","author":"Jampel","year":"2005","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"10.1016\/j.ogla.2021.08.005_bib7","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1007\/s40123-016-0054-6","article-title":"The new era of glaucoma micro-stent surgery","volume":"5","author":"Manasses","year":"2016","journal-title":"Ophthalmol Ther"},{"issue":"1","key":"10.1016\/j.ogla.2021.08.005_bib8","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1111\/cts.12660","article-title":"Translating minimally invasive glaucoma surgery devices","volume":"13","author":"Lee","year":"2020","journal-title":"Clin Transl Sci"},{"issue":"4","key":"10.1016\/j.ogla.2021.08.005_bib9","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.biomaterials.2007.09.041","article-title":"Medical applications of poly(styrene-block-isobutylene-block-styrene) (\u201cSIBS\u201d)","volume":"29","author":"Pinchuk","year":"2008","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.ogla.2021.08.005_bib10","doi-asserted-by":"crossref","first-page":"27","DOI":"10.17925\/EOR.2019.13.1.27","article-title":"Minimally invasive glaucoma surgery with a new ab-externo subconjunctival bypass\u2014current status and review of literature","volume":"13","author":"Beckers","year":"2019","journal-title":"European Ophthalmic Review"},{"issue":"9","key":"10.1016\/j.ogla.2021.08.005_bib11","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1016\/j.jfo.2015.05.005","article-title":"[One-year results on the safety and efficacy of the InnFocus MicroShunt\u2122 depending on placement and concentration of mitomycin C]","volume":"38","author":"Riss","year":"2015","journal-title":"J\u00a0Fr Ophtalmol"},{"issue":"2","key":"10.1016\/j.ogla.2021.08.005_bib12","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1097\/IJG.0000000000000368","article-title":"Three-year follow-up of a novel aqueous humor microshunt","volume":"25","author":"Batlle","year":"2016","journal-title":"J\u00a0Glaucoma"},{"issue":"3","key":"10.1016\/j.ogla.2021.08.005_bib13","doi-asserted-by":"crossref","first-page":"e433","DOI":"10.1111\/aos.14602","article-title":"XEN\u00ae Gel Stent compared to PRESERFLO\u2122 MicroShunt implantation for primary open-angle glaucoma: two-year results","volume":"99","author":"Scheres","year":"2021","journal-title":"Acta Ophthalmol"},{"issue":"3","key":"10.1016\/j.ogla.2021.08.005_bib14","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/IJG.0000000000001734","article-title":"Long-term results of the PRESERFLO\u00ae MicroShunt in patients with primary open-angle glaucoma from a single-center non-randomized study","volume":"30","author":"Batlle","year":"2021","journal-title":"J\u00a0Glaucoma"},{"key":"10.1016\/j.ogla.2021.08.005_bib15","unstructured":"Beckers H, Aptel F, Webers C, et\u00a0al. Two-year results of a multicentre study assessing the MicroShunt in patients with primary open-angle glaucoma: 0.4 mg\/ml mitomycin C outcomes. Poster presented at the 37th Congress of the ESCRS, 2019. Paris (France). Available at: https:\/\/www.escrs.org\/paris2019\/programme\/posters-details.asp?id=33176; 2019 Accessed 06.06.21."},{"key":"10.1016\/j.ogla.2021.08.005_bib16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.ajo.2020.02.020","article-title":"Intermediate outcomes of a novel standalone ab externo SIBS microshunt with mitomycin C","volume":"215","author":"Schlenker","year":"2020","journal-title":"Am J Ophthalmol"},{"issue":"12","key":"10.1016\/j.ogla.2021.08.005_bib17","doi-asserted-by":"crossref","first-page":"1710","DOI":"10.1016\/j.ophtha.2021.05.023","article-title":"Ab-externo microshunt versus trabeculectomy in primary open-angle glaucoma: one-year results from a 2-year randomized, multicenter study","volume":"128","author":"Baker","year":"2021","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.ogla.2021.08.005_bib18","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3102\/10769986030002141","article-title":"On the post hoc power in testing mean differences","volume":"30","author":"Yuan","year":"2005","journal-title":"J\u00a0Educ Behav Stat"},{"issue":"7","key":"10.1016\/j.ogla.2021.08.005_bib19","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1001\/jamaophthalmol.2014.856","article-title":"Electronic monitoring to assess adherence with once-daily glaucoma medications and risk factors for nonadherence: the automated dosing reminder study","volume":"132","author":"Boland","year":"2014","journal-title":"JAMA Ophthalmol"},{"issue":"10","key":"10.1016\/j.ogla.2021.08.005_bib20","doi-asserted-by":"crossref","first-page":"2010","DOI":"10.1016\/j.ophtha.2015.06.039","article-title":"Patterns of glaucoma medication adherence over four years of follow-up","volume":"122","author":"Newman-Casey","year":"2015","journal-title":"Ophthalmology"},{"issue":"4","key":"10.1016\/j.ogla.2021.08.005_bib21","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.ophtha.2019.10.022","article-title":"The association between medication adherence and visual field progression in the Collaborative Initial Glaucoma Treatment Study","volume":"127","author":"Newman-Casey","year":"2020","journal-title":"Ophthalmology"},{"issue":"5","key":"10.1016\/j.ogla.2021.08.005_bib22","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.ajo.2011.10.026","article-title":"Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up","volume":"153","author":"Gedde","year":"2012","journal-title":"Am J Ophthalmol"},{"issue":"5","key":"10.1016\/j.ogla.2021.08.005_bib23","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.ophtha.2018.02.003","article-title":"Treatment outcomes in the primary Tube Versus Trabeculectomy Study after 1 year of follow-up","volume":"125","author":"Gedde","year":"2018","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ogla.2021.08.005_bib24","unstructured":"Santen Pharmaceutical. Santen announces topline data for DE-128 (MicroShunt) demonstrating reductions in IOP and medication use in patients with glaucoma [press release]. August 30, 2019. Available at: https:\/\/eyewire.news\/articles\/santen-announces-topline-data-for-de-128-microshunt-demonstrating-reductions-in-iop-and-medication-use-in-patients-with-glaucoma; 2019 Accessed 06.06.21."},{"issue":"9","key":"10.1016\/j.ogla.2021.08.005_bib25","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0239324","article-title":"Numerical model to predict and compare the hypotensive efficacy and safety of minimally invasive glaucoma surgery devices","volume":"15","author":"Kudsieh","year":"2020","journal-title":"PLoS One"},{"issue":"Suppl 1","key":"10.1016\/j.ogla.2021.08.005_bib26","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1159\/000267859","article-title":"The blood-aqueous barrier in eyes with pseudoexfoliation syndrome","volume":"27","author":"K\u00fcchle","year":"1995","journal-title":"Ophthalmic Res"},{"issue":"6","key":"10.1016\/j.ogla.2021.08.005_bib27","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1001\/archopht.117.6.733","article-title":"Quantification of aqueous flare after phacoemulsification with intraocular lens implantation in eyes with pseudoexfoliation syndrome","volume":"117","author":"Schumacher","year":"1999","journal-title":"Arch Ophthalmol"},{"issue":"8","key":"10.1016\/j.ogla.2021.08.005_bib28","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1016\/j.jcrs.2012.04.028","article-title":"Simultaneous increases in multiple proinflammatory cytokines in the aqueous humor in pseudophakic glaucomatous eyes","volume":"38","author":"Inoue","year":"2012","journal-title":"J\u00a0Cataract Refract Surg"},{"issue":"1","key":"10.1016\/j.ogla.2021.08.005_bib29","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1001\/jamaophthalmol.2013.5605","article-title":"Trabeculectomy for open-angle glaucoma in phakic eyes vs in pseudophakic eyes after phacoemulsification: a prospective clinical cohort study","volume":"132","author":"Takihara","year":"2014","journal-title":"JAMA Ophthalmol"},{"issue":"10","key":"10.1016\/j.ogla.2021.08.005_bib30","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1136\/bjophthalmol-2018-312972","article-title":"Success of trabeculectomy surgery in relation to cataract surgery: 5-year outcomes","volume":"103","author":"Mathew","year":"2019","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ogla.2021.08.005_bib31","first-page":"1945","article-title":"A\u00a0review of the efficacy of mitomycin C in glaucoma filtration surgery","volume":"9","author":"Al Habash","year":"2015","journal-title":"Clin Ophthalmol"}],"container-title":["Ophthalmology Glaucoma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589419621001903?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2589419621001903?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T18:53:06Z","timestamp":1762887186000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2589419621001903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["S2589419621001903"],"URL":"https:\/\/doi.org\/10.1016\/j.ogla.2021.08.005","relation":{},"ISSN":["2589-4196"],"issn-type":[{"value":"2589-4196","type":"print"}],"subject":[],"published":{"date-parts":[[2022,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effectiveness of MicroShunt in Patients with Primary Open-Angle and Pseudoexfoliative Glaucoma","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology Glaucoma","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ogla.2021.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 by the American Academy of Ophthalmology.","name":"copyright","label":"Copyright"}]}}