{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T21:14:06Z","timestamp":1788556446713,"version":"build-2803163510"},"reference-count":52,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T00:00:00Z","timestamp":1771286400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","award":["EY000470"],"award-info":[{"award-number":["EY000470"]}],"id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy Advances"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.omta.2026.201705","type":"journal-article","created":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T07:56:40Z","timestamp":1771574200000},"page":"201705","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Gene therapy induces pigmentation in induced pluripotent stem cell-derived retinal pigment epithelium of OCA1A patients and albino rat eye"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-1955-9599","authenticated-orcid":false,"given":"Aman","family":"George","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnold","family":"Leigh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Selzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tyler","family":"Pfister","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"DeYoung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Villasmil","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mones","family":"Abu-Asab","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suja","family":"Hiriyanna","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philsang","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruchi","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arvydas","family":"Maminishkis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiansen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian P.","family":"Brooks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.omta.2026.201705_bib1","series-title":"The Online Metabolic and Molecular Bases of Inherited Disease (Vol. 1\u2013Book, Section)","article-title":"Albinism","author":"King","year":"2019"},{"key":"10.1016\/j.omta.2026.201705_bib2","series-title":"Ortonne J-P (eds). The Pigmentary System: Physiology and Pathophysiology","author":"Nordlund","year":"2007"},{"key":"10.1016\/j.omta.2026.201705_bib3","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1471-5945-12-5","article-title":"Skin cancers among Albinos at a University teaching hospital in Northwestern Tanzania: A retrospective review of 64 cases","volume":"12","author":"Mabula","year":"2012","journal-title":"BMC Dermatol."},{"key":"10.1016\/j.omta.2026.201705_bib4","series-title":"NORD","year":"2015"},{"key":"10.1016\/j.omta.2026.201705_bib5","series-title":"Ocular Disease","first-page":"461","article-title":"Albinism","author":"Cox","year":"2010"},{"key":"10.1016\/j.omta.2026.201705_bib6","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1038\/mt.2009.112","article-title":"AAV-mediated Tyrosinase Gene Transfer Restores Melanogenesis and Retinal Function in a Model of Oculo-cutaneous Albinism Type I (OCA1)","volume":"17","author":"Gargiulo","year":"2009","journal-title":"Mol. Ther."},{"key":"10.1016\/j.omta.2026.201705_bib7","doi-asserted-by":"crossref","first-page":"4901","DOI":"10.1172\/JCI129085","article-title":"AAV8-vectored suprachoroidal gene transfer produces widespread ocular transgene expression","volume":"129","author":"Ding","year":"2019","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.omta.2026.201705_bib8","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.stemcr.2021.11.016","article-title":"In vitro disease modeling of oculocutaneous albinism type 1 and 2 using human induced pluripotent stem cell-derived retinal pigment epithelium","volume":"17","author":"George","year":"2022","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.omta.2026.201705_bib9","first-page":"1095","article-title":"Vision in albinism","volume":"94","author":"Summers","year":"1996","journal-title":"Trans. Am. Ophthalmol. Soc."},{"key":"10.1016\/j.omta.2026.201705_bib10","doi-asserted-by":"crossref","first-page":"802","DOI":"10.2174\/156652410793937813","article-title":"The retinal pigment epithelium in health and disease","volume":"10","author":"Sparrow","year":"2010","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.omta.2026.201705_bib11","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1146\/annurev-pharmtox-010919-023245","article-title":"Retinal Pigment Epithelium Replacement Therapy for Age-Related Macular Degeneration: Are We There Yet?","volume":"60","author":"Sharma","year":"2020","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1016\/j.omta.2026.201705_bib12","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/S0140-6736(17)31868-8","article-title":"Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: A randomised, controlled, open-label, phase 3 trial","volume":"390","author":"Russell","year":"2017","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.omta.2026.201705_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.xpro.2022.101582","article-title":"Triphasic developmentally guided protocol to generate retinal pigment epithelium from induced pluripotent stem cells","volume":"3","author":"Sharma","year":"2022","journal-title":"STAR Protoc."},{"key":"10.1016\/j.omta.2026.201705_bib16","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1111\/j.1600-0749.2005.00227.x","article-title":"A Tyrosinase missense mutation causes albinism in the Wistar rat","volume":"18","author":"Blaszczyk","year":"2005","journal-title":"Pigment Cell Res."},{"key":"10.1016\/j.omta.2026.201705_bib52","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1038\/70591","article-title":"Retinopathy and attenuated circadian entrainment in Crx-deficient mice","volume":"23","author":"Furukawa","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1016\/j.omta.2026.201705_bib14","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/978-1-4939-9139-6_7","article-title":"Use of AAV Vectors for CRISPR-Mediated In Vivo Genome Editing in the Retina","volume":"1950","author":"Yu","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.omta.2026.201705_bib17","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1016\/0003-9861(92)90032-R","article-title":"Generation of superoxide during the enzymatic action of tyrosinase","volume":"292","author":"Koga","year":"1992","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.omta.2026.201705_bib18","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1111\/j.1755-148X.2009.00610.x","article-title":"Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function","volume":"22","author":"Simon","year":"2009","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.omta.2026.201705_bib19","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.jaapos.2006.01.008","article-title":"Spectrum of Foveal Development in Albinism Detected with Optical Coherence Tomography","volume":"10","author":"Harvey","year":"2006","journal-title":"J. Am. Assoc. Pediatr. Ophthalmol. Strabismus"},{"key":"10.1016\/j.omta.2026.201705_bib20","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/0042-6989(86)90143-4","article-title":"A qualitative and quantitative analysis of the human fovea during development","volume":"26","author":"Yuodelis","year":"1986","journal-title":"Vision Res."},{"key":"10.1016\/j.omta.2026.201705_bib21","doi-asserted-by":"crossref","DOI":"10.1038\/mtm.2014.11","article-title":"Proof of concept for AAV2\/5-mediated gene therapy in iPSC-derived retinal pigment epithelium of a choroideremia patient","volume":"1","author":"Cereso","year":"2014","journal-title":"Mol. Ther. Methods Clin. Dev."},{"key":"10.1016\/j.omta.2026.201705_bib22","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/j.omtm.2019.10.014","article-title":"AAV-Mediated Gene Augmentation Therapy Restores Critical Functions in Mutant PRPF31+\/- iPSC-Derived RPE Cells","volume":"15","author":"Brydon","year":"2019","journal-title":"Mol. Ther. Methods Clin. Dev."},{"key":"10.1016\/j.omta.2026.201705_bib23","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/hmg\/ddac181","article-title":"AAV-mediated gene-replacement therapy restores viability of BCD patient iPSC derived RPE cells and vision of Cyp4v3 knockout mice","volume":"32","author":"Jia","year":"2023","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.omta.2026.201705_bib24","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.ajhg.2020.06.011","article-title":"Human iPSC Modeling Reveals Mutation-Specific Responses to Gene Therapy in a Genotypically Diverse Dominant Maculopathy","volume":"107","author":"Sinha","year":"2020","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.omta.2026.201705_bib25","doi-asserted-by":"crossref","first-page":"10020","DOI":"10.1111\/jcmm.16911","article-title":"Gene replacement therapy restores RCBTB1 expression and cilium length in patient-derived retinal pigment epithelium","volume":"25","author":"Huang","year":"2021","journal-title":"J. Cell Mol. Med."},{"key":"10.1016\/j.omta.2026.201705_bib26","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/s41536-022-00235-6","article-title":"Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue","volume":"7","author":"Rodrigues","year":"2022","journal-title":"NPJ Regen. Med."},{"key":"10.1016\/j.omta.2026.201705_bib27","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1089\/jop.2019.0126","article-title":"Suprachoroidal Delivery of Viral and Nonviral Gene Therapy for Retinal Diseases","volume":"36","author":"Kansara","year":"2020","journal-title":"J. Ocul. Pharmacol. Ther."},{"key":"10.1016\/j.omta.2026.201705_bib28","article-title":"Ocular Gene Therapy: A Literature Review With Focus on Current Clinical Trials","volume":"14","author":"Wasnik","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.omta.2026.201705_bib29","doi-asserted-by":"crossref","first-page":"1910","DOI":"10.1167\/iovs.17-22494","article-title":"Humoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients","volume":"59","author":"Reichel","year":"2018","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"key":"10.1016\/j.omta.2026.201705_bib30","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aba1606","article-title":"Suprachoroidal gene transfer with nonviral nanoparticles","volume":"6","author":"Shen","year":"2020","journal-title":"Sci. Adv."},{"key":"10.1016\/j.omta.2026.201705_bib31","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.omtm.2020.01.002","article-title":"Suprachoroidal and Subretinal Injections of AAV Using Transscleral Microneedles for Retinal Gene Delivery in Nonhuman Primates","volume":"16","author":"Yiu","year":"2020","journal-title":"Mol. Ther. Methods Clin. Dev."},{"key":"10.1016\/j.omta.2026.201705_bib32","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1089\/hum.2020.281","article-title":"Host Immune Responses after Suprachoroidal Delivery of AAV8 in Nonhuman Primate Eyes","volume":"32","author":"Chung","year":"2021","journal-title":"Hum. Gene Ther."},{"key":"10.1016\/j.omta.2026.201705_bib33","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1007\/s40265-022-01777-1","article-title":"Suprachoroidal Space Triamcinolone Acetonide: A Review in Uveitic Macular Edema","volume":"82","author":"Fung","year":"2022","journal-title":"Drugs"},{"key":"10.1016\/j.omta.2026.201705_bib34","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1136\/bjophthalmol-2020-318019","article-title":"Suprachoroidal CLS-TA for non-infectious uveitis: An open-label, safety trial (AZALEA)","volume":"106","author":"Henry","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.omta.2026.201705_bib35","article-title":"Safety and Efficacy of Suprachoroidal Injection of Triamcinolone in Treating Macular Edema Secondary to Noninfectious Uveitis","volume":"13","author":"Hanif","year":"2021","journal-title":"Cureus"},{"key":"10.1016\/j.omta.2026.201705_bib36","doi-asserted-by":"crossref","first-page":"1880","DOI":"10.1097\/IAE.0000000000002279","article-title":"Suprachoroidal injection of triamcinolone acetonide, cls-ta, for macular edema due to noninfectious uveitis: A Randomized, Phase 2 Study (DOGWOOD)","volume":"39","author":"Yeh","year":"2019","journal-title":"Retina"},{"key":"10.1016\/j.omta.2026.201705_bib37","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1167\/tvst.5.6.14","article-title":"Suprachoroidal Corticosteroid Administration: A Novel Route for Local Treatment of Noninfectious Uveitis","volume":"5","author":"Goldstein","year":"2016","journal-title":"Transl. Vis. Sci. Technol."},{"key":"10.1016\/j.omta.2026.201705_bib38","first-page":"1139","article-title":"Extension study of the safety and efficacy of CLS-TA for treatment of macular oedema associated with non-infectious uveitis (MAGNOLIA)","volume":"106","author":"Khurana","year":"2022","journal-title":"Br. J. Ophthalmol."},{"key":"10.1016\/j.omta.2026.201705_bib39","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1016\/j.ophtha.2020.01.006","article-title":"Efficacy and Safety of Suprachoroidal CLS-TA for Macular Edema Secondary to Noninfectious Uveitis: Phase 3 Randomized Trial","volume":"127","author":"Yeh","year":"2020","journal-title":"Ophthalmology"},{"key":"10.1016\/j.omta.2026.201705_bib40","doi-asserted-by":"crossref","DOI":"10.1177\/03000605221089807","article-title":"Suprachoroidal injection of triamcinolone acetonide using a custom-made needle to treat diabetic macular edema post pars plana vitrectomy: A case series","volume":"50","author":"Marashi","year":"2022","journal-title":"J. Int. Med. Res."},{"key":"10.1016\/j.omta.2026.201705_bib41","doi-asserted-by":"crossref","first-page":"733","DOI":"10.2147\/OPTH.S351853","article-title":"Suprachoroidal versus Intravitreal Triamcinolone Acetonide for the Treatment of Diabetic Macular Edema","volume":"16","author":"Zakaria","year":"2022","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.omta.2026.201705_bib42","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/7947710","article-title":"A Randomized Trial Comparing Suprachoroidal and Intravitreal Injection of Triamcinolone Acetonide in Refractory Diabetic Macular Edema due to Epiretinal Membrane","volume":"2022","author":"Abdelshafy Tabl","year":"2022","journal-title":"J. Ophthalmol."},{"key":"10.1016\/j.omta.2026.201705_bib43","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.oret.2020.08.007","article-title":"Suprachoroidal CLS-TA plus Intravitreal Aflibercept for Diabetic Macular Edema: A Randomized, Double-Masked, Parallel-Design, Controlled Study","volume":"5","author":"Barakat","year":"2021","journal-title":"Ophthalmol. Retina"},{"key":"10.1016\/j.omta.2026.201705_bib44","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.2147\/OPTH.S361636","article-title":"Modified Microneedle for Suprachoroidal Injection of Triamcinolone Acetonide Combined with Intravitreal Injection of Ranibizumab in Branch Retinal Vein Occlusion Patients","volume":"16","author":"Nawar","year":"2022","journal-title":"Clin. Ophthalmol."},{"key":"10.1016\/j.omta.2026.201705_bib45","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.oret.2017.07.013","article-title":"Suprachoroidal Triamcinolone Acetonide for Retinal Vein Occlusion: Results of the Tanzanite Study","volume":"2","author":"Campochiaro","year":"2018","journal-title":"Ophthalmol. Retina"},{"key":"10.1016\/j.omta.2026.201705_bib46","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.4103\/ijo.IJO_1788_21","article-title":"Safety and efficacy of suprachoroidal triamcinolone acetonide for the management of serous choroidal detachment prior to rhegmatogenous retinal detachment surgery: A Pilot study","volume":"70","author":"Kohli","year":"2022","journal-title":"Indian J. Ophthalmol."},{"key":"10.1016\/j.omta.2026.201705_bib47","doi-asserted-by":"crossref","first-page":"3482","DOI":"10.1177\/11206721221085420","article-title":"Suprachoroidal triamcinolone acetonide injection: A novel therapy for serous retinal detachment due to Vogt-Koyanagi Harada disease","volume":"32","author":"Tabl","year":"2022","journal-title":"Eur. J. Ophthalmol."},{"key":"10.1016\/j.omta.2026.201705_bib48","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1186\/s13256-021-03162-0","article-title":"Managing solar retinopathy with suprachoroidal triamcinolone acetonide injection in a young girl: A case report","volume":"15","author":"Marashi","year":"2021","journal-title":"J. Med. Case Rep."},{"key":"10.1016\/j.omta.2026.201705_bib49","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.jconrel.2022.10.036","article-title":"Six-month sustained delivery of anti-VEGF from in-situ forming hydrogel in the suprachoroidal space","volume":"352","author":"Jung","year":"2022","journal-title":"J. Control. Release"},{"key":"10.1016\/j.omta.2026.201705_bib50","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ejpb.2021.10.003","article-title":"Suprachoroidal delivery of bevacizumab in rabbit in vivo eyes: Rapid distribution throughout the posterior segment","volume":"169","author":"Sher","year":"2021","journal-title":"Eur. J. Pharm. Biopharm."},{"key":"10.1016\/j.omta.2026.201705_bib51","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1167\/tvst.10.7.19","article-title":"Evaluation of Long-Lasting Potential of Suprachoroidal Axitinib Suspension Via Ocular and Systemic Disposition in Rabbits","volume":"10","author":"Kansara","year":"2021","journal-title":"Transl. Vis. Sci. Technol."},{"key":"10.1016\/j.omta.2026.201705_bib15","first-page":"1.21","article-title":"Separation Index: An Easy-to-Use Metric for Evaluation of Different Configurations on the Same Flow Cytometer","volume":"1","author":"Bigos","year":"2007","journal-title":"Curr. Protoc. Cytom."}],"container-title":["Molecular Therapy Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S3117387X26000406?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S3117387X26000406?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:32:12Z","timestamp":1788553932000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S3117387X26000406"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":52,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S3117387X26000406"],"URL":"https:\/\/doi.org\/10.1016\/j.omta.2026.201705","relation":{},"ISSN":["3117-387X"],"issn-type":[{"value":"3117-387X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Gene therapy induces pigmentation in induced pluripotent stem cell-derived retinal pigment epithelium of OCA1A patients and albino rat eye","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.omta.2026.201705","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc. on behalf of The American Society of Gene and Cell Therapy.","name":"copyright","label":"Copyright"}],"article-number":"201705"}}