{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:09:49Z","timestamp":1790744989109,"version":"4.1.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,6,30]],"date-time":"2017-06-30T00:00:00Z","timestamp":1498780800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100019725","name":"DEBRA Austria","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002347","name":"Bundesministerium f\u00fcr Bildung und Forschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002347","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006603","name":"Bundesministerium f\u00fcr Bildung und Frauen","doi-asserted-by":"publisher","award":["01EO0803"],"award-info":[{"award-number":["01EO0803"]}],"id":[{"id":"10.13039\/501100006603","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy - Methods &amp; Clinical Development"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.omtm.2017.06.008","type":"journal-article","created":{"date-parts":[[2017,7,4]],"date-time":"2017-07-04T21:33:37Z","timestamp":1499204017000},"page":"112-123","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":48,"special_numbering":"C","title":["Traceless Targeting and Isolation of Gene-Edited Immortalized Keratinocytes from Epidermolysis Bullosa Simplex Patients"],"prefix":"10.1016","volume":"6","author":[{"given":"Magomet","family":"Aushev","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Koller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudio","family":"Mussolino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toni","family":"Cathomen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Reichelt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.omtm.2017.06.008_bib1","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1083\/jcb.200810196","article-title":"Self-organization of keratin intermediate filaments into cross-linked networks","volume":"186","author":"Lee","year":"2009","journal-title":"J.\u00a0Cell Biol."},{"key":"10.1016\/j.omtm.2017.06.008_bib2","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/humu.20652","article-title":"The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases","volume":"29","author":"Szeverenyi","year":"2008","journal-title":"Hum. Mutat."},{"key":"10.1016\/j.omtm.2017.06.008_bib3","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1146\/annurev.cb.11.110195.001011","article-title":"Keratins and the skin","volume":"11","author":"Fuchs","year":"1995","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.omtm.2017.06.008_bib4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/ncb3282","article-title":"Human keratinocytes have two interconvertible modes of proliferation","volume":"18","author":"Roshan","year":"2016","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.omtm.2017.06.008_bib5","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1073\/pnas.90.8.3197","article-title":"Disease severity correlates with position of keratin point mutations in patients with epidermolysis bullosa simplex","volume":"90","author":"Letai","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.omtm.2017.06.008_bib6","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1046\/j.1523-1747.1999.00495.x","article-title":"Identification of novel and known mutations in the genes for keratin 5 and 14 in Danish patients with epidermolysis bullosa simplex: correlation between genotype and phenotype","volume":"112","author":"S\u00f8rensen","year":"1999","journal-title":"J.\u00a0Invest. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib7","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1111\/1523-1747.ep12491885","article-title":"Epidermolysis bullosa simplex (Dowling-Meara type) is a genetic disease characterized by an abnormal keratin-filament network involving keratins K5 and K14","volume":"97","author":"Ishida-Yamamoto","year":"1991","journal-title":"J.\u00a0Invest. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib8","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1007\/BF00424265","article-title":"Abnormal organization of keratin intermediate filaments in cultured keratinocytes of epidermolysis bullosa simplex","volume":"281","author":"Kitajima","year":"1989","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.omtm.2017.06.008_bib9","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jdermsci.2008.11.003","article-title":"Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition","volume":"53","author":"Chamcheu","year":"2009","journal-title":"J.\u00a0Dermatol. Sci."},{"key":"10.1016\/j.omtm.2017.06.008_bib10","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1111\/j.1365-2133.2009.09615.x","article-title":"Epidermolysis bullosa simplex due to KRT5 mutations: mutation-related differences in cellular fragility and the protective effects of trimethylamine N-oxide in cultured primary keratinocytes","volume":"162","author":"Chamcheu","year":"2010","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib11","doi-asserted-by":"crossref","first-page":"1684","DOI":"10.1038\/jid.2011.93","article-title":"Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases","volume":"131","author":"Chamcheu","year":"2011","journal-title":"J.\u00a0Invest. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib12","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1101\/gad.8.21.2563","article-title":"A functional \u201cknockout\u201d of human keratin 14","volume":"8","author":"Rugg","year":"1994","journal-title":"Genes Dev."},{"key":"10.1016\/j.omtm.2017.06.008_bib13","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1101\/gad.8.21.2574","article-title":"A human keratin 14 \u201cknockout\u201d: the absence of K14 leads to severe epidermolysis bullosa simplex and a function for an intermediate filament protein","volume":"8","author":"Chan","year":"1994","journal-title":"Genes Dev."},{"key":"10.1016\/j.omtm.2017.06.008_bib14","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1093\/hmg\/ddl028","article-title":"A human keratin 10 knockout causes recessive epidermolytic hyperkeratosis","volume":"15","author":"M\u00fcller","year":"2006","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.omtm.2017.06.008_bib15","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1196\/annals.1348.059","article-title":"SiRNA-mediated selective inhibition of mutant keratin mRNAs responsible for the skin disorder pachyonychia congenita","volume":"1082","author":"Hickerson","year":"2006","journal-title":"Ann. N Y Acad. Sci."},{"key":"10.1016\/j.omtm.2017.06.008_bib16","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1038\/sj.jid.5701060","article-title":"Single-nucleotide-specific siRNA targeting in a dominant-negative skin model","volume":"128","author":"Hickerson","year":"2008","journal-title":"J.\u00a0Invest. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib17","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/mt.2009.273","article-title":"First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder","volume":"18","author":"Leachman","year":"2010","journal-title":"Mol. Ther."},{"key":"10.1016\/j.omtm.2017.06.008_bib18","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1038\/jid.2011.169","article-title":"Development of allele-specific therapeutic siRNA for keratin 5 mutations in epidermolysis bullosa simplex","volume":"131","author":"Atkinson","year":"2011","journal-title":"J.\u00a0Invest. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib19","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/nature07758","article-title":"The promises and pitfalls of RNA-interference-based therapeutics","volume":"457","author":"Castanotto","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.omtm.2017.06.008_bib20","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1002\/emmm.200900023","article-title":"RNAi-based therapeutics-current status, challenges and prospects","volume":"1","author":"Tiemann","year":"2009","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib21","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1002\/jgm.665","article-title":"Myocardial gene transfer and long-term expression following intracoronary delivery of adeno-associated virus","volume":"7","author":"Kaspar","year":"2005","journal-title":"J.\u00a0Gene Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib22","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1038\/nrg3686","article-title":"A guide to genome engineering with programmable nucleases","volume":"15","author":"Kim","year":"2014","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.omtm.2017.06.008_bib23","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nm.3793","article-title":"Therapeutic genome editing: prospects and challenges","volume":"21","author":"Cox","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib24","first-page":"8096","article-title":"Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease","volume":"14","author":"Rouet","year":"1994","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.omtm.2017.06.008_bib25","doi-asserted-by":"crossref","first-page":"2302","DOI":"10.1073\/pnas.84.8.2302","article-title":"Three clonal types of keratinocyte with different capacities for multiplication","volume":"84","author":"Barrandon","year":"1987","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.omtm.2017.06.008_bib26","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1056\/NEJM198408163110706","article-title":"Permanent coverage of large burn wounds with autologous cultured human epithelium","volume":"311","author":"Gallico","year":"1984","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib27","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1097\/00007890-200012150-00009","article-title":"Long-term regeneration of human epidermis on third degree burns transplanted with autologous cultured epithelium grown on a fibrin matrix","volume":"70","author":"Ronfard","year":"2000","journal-title":"Transplantation"},{"key":"10.1016\/j.omtm.2017.06.008_bib28","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1038\/nm1504","article-title":"Correction of junctional epidermolysis bullosa by transplantation of genetically modified epidermal stem cells","volume":"12","author":"Mavilio","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib29","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.jid.2016.10.038","article-title":"Closure of a large chronic wound through transplantation of gene-corrected epidermal stem cells","volume":"137","author":"Bauer","year":"2017","journal-title":"J.\u00a0Invest. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib30","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1007\/s12015-011-9313-z","article-title":"Highly efficient zinc-finger nuclease-mediated disruption of an eGFP transgene in keratinocyte stem cells without impairment of stem cell properties","volume":"8","author":"H\u00f6her","year":"2012","journal-title":"Stem Cell Rev."},{"key":"10.1016\/j.omtm.2017.06.008_bib31","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2217\/17460751.1.1.45","article-title":"Regeneration of squamous epithelia from stem cells of cultured grafts","volume":"1","author":"De Luca","year":"2006","journal-title":"Regen. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.stemcr.2013.11.001","article-title":"Long-term stability and safety of transgenic cultured epidermal stem cells in gene therapy of junctional epidermolysis bullosa","volume":"2","author":"De Rosa","year":"2013","journal-title":"Stem Cell Reports"},{"key":"10.1016\/j.omtm.2017.06.008_bib33","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.semcdb.2012.09.011","article-title":"Capturing epidermal stemness for regenerative medicine","volume":"23","author":"Barrandon","year":"2012","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.omtm.2017.06.008_bib34","series-title":"Handbook of Stem Cells","first-page":"766","article-title":"Regeneration of epidermis from adult human keratinocytes stem cells","author":"Rochat","year":"2013"},{"key":"10.1016\/j.omtm.2017.06.008_bib35","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/nm.4313","article-title":"Refining strategies to translate genome editing to the clinic","volume":"23","author":"Cornu","year":"2017","journal-title":"Nat. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib36","article-title":"Gene editing for skin diseases: designer nucleases as tools for gene therapy of skin fragility disorders","author":"March","year":"2017","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.omtm.2017.06.008_bib37","doi-asserted-by":"crossref","first-page":"9283","DOI":"10.1093\/nar\/gkr597","article-title":"A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity","volume":"39","author":"Mussolino","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.omtm.2017.06.008_bib38","doi-asserted-by":"crossref","first-page":"6762","DOI":"10.1093\/nar\/gku305","article-title":"TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity","volume":"42","author":"Mussolino","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.omtm.2017.06.008_bib39","doi-asserted-by":"crossref","first-page":"2769","DOI":"10.1093\/nar\/gks1356","article-title":"A large-scale in\u00a0vivo analysis reveals that TALENs are significantly more mutagenic than ZFNs generated using context-dependent assembly","volume":"41","author":"Chen","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.omtm.2017.06.008_bib40","doi-asserted-by":"crossref","first-page":"5368","DOI":"10.1093\/nar\/gks199","article-title":"Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers","volume":"40","author":"Bultmann","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.omtm.2017.06.008_bib41","doi-asserted-by":"crossref","first-page":"38427","DOI":"10.1074\/jbc.C112.408864","article-title":"Overcoming transcription activator-like effector (TALE) DNA binding domain sensitivity to cytosine methylation","volume":"287","author":"Valton","year":"2012","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.omtm.2017.06.008_bib42","doi-asserted-by":"crossref","first-page":"5390","DOI":"10.1073\/pnas.82.16.5390","article-title":"Cell size as a determinant of the clone-forming ability of human keratinocytes","volume":"82","author":"Barrandon","year":"1985","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.omtm.2017.06.008_bib43","doi-asserted-by":"crossref","first-page":"1695","DOI":"10.1038\/mt.2013.143","article-title":"Targeted gene addition in human epithelial stem cells by zinc-finger nuclease-mediated homologous recombination","volume":"21","author":"Coluccio","year":"2013","journal-title":"Mol. Ther."},{"key":"10.1016\/j.omtm.2017.06.008_bib44","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1016\/0092-8674(94)90383-2","article-title":"Location of stem cells of human hair follicles by clonal analysis","volume":"76","author":"Rochat","year":"1994","journal-title":"Cell"},{"key":"10.1016\/j.omtm.2017.06.008_bib45","doi-asserted-by":"crossref","first-page":"10371","DOI":"10.1073\/pnas.93.19.10371","article-title":"Clonal analysis of stably transduced human epidermal stem cells in culture","volume":"93","author":"Mathor","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.omtm.2017.06.008_bib46","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.stem.2016.05.012","article-title":"Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells","volume":"19","author":"Mou","year":"2016","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.omtm.2017.06.008_bib47","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1038\/mt.2013.56","article-title":"TALEN-based gene correction for epidermolysis bullosa","volume":"21","author":"Osborn","year":"2013","journal-title":"Mol. Ther."},{"key":"10.1016\/j.omtm.2017.06.008_bib48","doi-asserted-by":"crossref","first-page":"380","DOI":"10.15252\/emmm.201404353","article-title":"A single epidermal stem cell strategy for safe ex\u00a0vivo gene therapy","volume":"7","author":"Droz-Georget Lathion","year":"2015","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib49","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1056\/NEJMoa1300662","article-title":"Gene editing of CCR5 in autologous CD4 T\u00a0cells of persons infected with HIV","volume":"370","author":"Tebas","year":"2014","journal-title":"N.\u00a0Engl. J. Med."},{"key":"10.1016\/j.omtm.2017.06.008_bib50","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1365-2133.2010.10092.x","article-title":"Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a useful in\u00a0vitro model for testing new treatments","volume":"164","author":"Chamcheu","year":"2011","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.omtm.2017.06.008_bib51","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1038\/nmeth.1456","article-title":"Transient cold shock enhances zinc-finger nuclease-mediated gene disruption","volume":"7","author":"Doyon","year":"2010","journal-title":"Nat. Methods"},{"key":"10.1016\/j.omtm.2017.06.008_bib52","doi-asserted-by":"crossref","first-page":"5790","DOI":"10.1093\/nar\/gkr151","article-title":"Assembly of custom TALE-type DNA binding domains by modular cloning","volume":"39","author":"Morbitzer","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.omtm.2017.06.008_bib53","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/978-1-60761-753-2_15","article-title":"A rapid and general assay for monitoring endogenous gene modification","volume":"649","author":"Guschin","year":"2010","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.omtm.2017.06.008_bib54","first-page":"1750","article-title":"Deletion of K1\/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity","volume":"125","author":"Wallace","year":"2012","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.omtm.2017.06.008_bib55","doi-asserted-by":"crossref","first-page":"4341","DOI":"10.1242\/jcs.00120","article-title":"Keratin mutations of epidermolysis bullosa simplex alter the kinetics of stress response to osmotic shock","volume":"115","author":"D\u2019Alessandro","year":"2002","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.omtm.2017.06.008_bib56","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gks608","article-title":"TAL Effector-Nucleotide Targeter (TALE-NT) 2.0: tools for TAL effector design and target prediction","volume":"40","author":"Doyle","year":"2012","journal-title":"Nucleic Acids Res."}],"container-title":["Molecular Therapy - Methods &amp; Clinical Development"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2329050117300839?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2329050117300839?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:21:38Z","timestamp":1762420898000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2329050117300839"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":56,"alternative-id":["S2329050117300839"],"URL":"https:\/\/doi.org\/10.1016\/j.omtm.2017.06.008","relation":{},"ISSN":["2329-0501"],"issn-type":[{"value":"2329-0501","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Traceless Targeting and Isolation of Gene-Edited Immortalized Keratinocytes from Epidermolysis Bullosa Simplex Patients","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy - Methods & Clinical Development","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.omtm.2017.06.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 The Author(s).","name":"copyright","label":"Copyright"}]}}