{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:50:26Z","timestamp":1792439426090,"version":"4.5.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,2,16]],"date-time":"2021-02-16T00:00:00Z","timestamp":1613433600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2019M661869"],"award-info":[{"award-number":["2019M661869"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004608","name":"Natural Science Foundation of Jiangsu Province","doi-asserted-by":"publisher","award":["BK20200563"],"award-info":[{"award-number":["BK20200563"]}],"id":[{"id":"10.13039\/501100004608","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31672422"],"award-info":[{"award-number":["31672422"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31972569"],"award-info":[{"award-number":["31972569"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy Nucleic Acids"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.omtn.2021.02.016","type":"journal-article","created":{"date-parts":[[2021,2,21]],"date-time":"2021-02-21T11:38:09Z","timestamp":1613907489000},"page":"54-66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Long non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b"],"prefix":"10.1016","volume":"24","author":[{"given":"Mingtian","family":"Deng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongjie","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baobao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangpeng","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zifei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingnan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanli","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.omtn.2021.02.016_bib1","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.stem.2018.06.018","article-title":"Somatic Cell Nuclear Transfer Reprogramming: Mechanisms and Applications","volume":"23","author":"Matoba","year":"2018","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib2","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1016\/j.theriogenology.2012.05.030","article-title":"Reprogramming mammalian somatic cells","volume":"78","author":"Rodriguez-Osorio","year":"2012","journal-title":"Theriogenology"},{"key":"10.1016\/j.omtn.2021.02.016_bib3","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/nature01079","article-title":"Somatic cell nuclear transfer","volume":"419","author":"Wilmut","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.omtn.2021.02.016_bib4","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1016\/j.cell.2013.05.006","article-title":"Human embryonic stem cells derived by somatic cell nuclear transfer","volume":"153","author":"Tachibana","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib5","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1038\/ng1973","article-title":"Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning","volume":"39","author":"Yang","year":"2007","journal-title":"Nat. Genet."},{"key":"10.1016\/j.omtn.2021.02.016_bib6","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1016\/j.stem.2015.10.001","article-title":"Histone Demethylase Expression Enhances Human Somatic Cell Nuclear Transfer Efficiency and Promotes Derivation of Pluripotent Stem Cells","volume":"17","author":"Chung","year":"2015","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib7","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/j.stem.2014.03.015","article-title":"Human somatic cell nuclear transfer using adult cells","volume":"14","author":"Chung","year":"2014","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib8","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.cell.2014.09.055","article-title":"Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation","volume":"159","author":"Matoba","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib9","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1146\/annurev-cellbio-100913-013027","article-title":"Zygotic genome activation during the maternal-to-zygotic transition","volume":"30","author":"Lee","year":"2014","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.omtn.2021.02.016_bib10","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.gde.2016.12.001","article-title":"The timing of zygotic genome activation","volume":"43","author":"P\u00e1lfy","year":"2017","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.omtn.2021.02.016_bib11","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1093\/biolre\/iox020","article-title":"WDR5 in porcine preimplantation embryos: expression, regulation of epigenetic modifications and requirement for early development","volume":"96","author":"Ding","year":"2017","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.omtn.2021.02.016_bib12","doi-asserted-by":"crossref","first-page":"e0144897","DOI":"10.1371\/journal.pone.0144897","article-title":"Genome-Wide Dynamic Profiling of Histone Methylation during Nuclear Transfer-Mediated Porcine Somatic Cell Reprogramming","volume":"10","author":"Cao","year":"2015","journal-title":"PLoS ONE"},{"key":"10.1016\/j.omtn.2021.02.016_bib13","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1093\/biolre\/ioy118","article-title":"Long noncoding RNAs exchange during zygotic genome activation in goat","volume":"99","author":"Deng","year":"2018","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.omtn.2021.02.016_bib14","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1159\/000487579","article-title":"Down-Regulation of H3K4me3 by MM-102 Facilitates Epigenetic Reprogramming of Porcine Somatic Cell Nuclear Transfer Embryos","volume":"45","author":"Zhang","year":"2018","journal-title":"Cell. Physiol. Biochem"},{"key":"10.1016\/j.omtn.2021.02.016_bib15","doi-asserted-by":"crossref","first-page":"dev158261","DOI":"10.1242\/dev.158261","article-title":"H3K9 demethylase KDM4E is an epigenetic regulator for bovine embryonic development and a defective factor for nuclear reprogramming","volume":"145","author":"Liu","year":"2018","journal-title":"Development"},{"key":"10.1016\/j.omtn.2021.02.016_bib16","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.stem.2017.03.003","article-title":"H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer Embryos","volume":"21","author":"H\u00f6rmanseder","year":"2017","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib17","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.molcel.2017.01.030","article-title":"Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways","volume":"65","author":"Jullien","year":"2017","journal-title":"Mol. Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib18","doi-asserted-by":"crossref","first-page":"4638","DOI":"10.1096\/fj.201801887R","article-title":"H3K27me3 is an epigenetic barrier while KDM6A overexpression improves nuclear reprogramming efficiency","volume":"33","author":"Zhou","year":"2019","journal-title":"FASEB J."},{"key":"10.1016\/j.omtn.2021.02.016_bib19","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.theriogenology.2016.04.021","article-title":"Epigenetic reprogramming in mammalian species after SCNT-based cloning","volume":"86","author":"Niemann","year":"2016","journal-title":"Theriogenology"},{"key":"10.1016\/j.omtn.2021.02.016_bib20","doi-asserted-by":"crossref","first-page":"13403","DOI":"10.1038\/s41598-017-13899-8","article-title":"Sperm-borne miR-449b influences cleavage, epigenetic reprogramming and apoptosis of SCNT embryos in bovine","volume":"7","author":"Wang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.omtn.2021.02.016_bib21","doi-asserted-by":"crossref","first-page":"15916","DOI":"10.1074\/jbc.M117.796771","article-title":"MicroRNA-125b is a key epigenetic regulatory factor that promotes nuclear transfer reprogramming","volume":"292","author":"Zhang","year":"2017","journal-title":"J.\u00a0Biol. Chem."},{"key":"10.1016\/j.omtn.2021.02.016_bib22","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1016\/j.stem.2014.05.014","article-title":"Long noncoding RNAs in cell-fate programming and reprogramming","volume":"14","author":"Flynn","year":"2014","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib23","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1093\/humupd\/dmw035","article-title":"Long non-coding RNAs in human early embryonic development and their potential in ART","volume":"23","author":"Bouckenheimer","year":"2016","journal-title":"Hum. Reprod. Update"},{"key":"10.1016\/j.omtn.2021.02.016_bib24","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1038\/nsmb.2660","article-title":"Single-cell RNA-Seq profiling of human preimplantation embryos and embryonic stem cells","volume":"20","author":"Yan","year":"2013","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.omtn.2021.02.016_bib25","first-page":"910","article-title":"Gene activation-associated long noncoding RNAs function in mouse preimplantation development","volume":"142","author":"Hamazaki","year":"2015","journal-title":"Development"},{"key":"10.1016\/j.omtn.2021.02.016_bib26","doi-asserted-by":"crossref","first-page":"38333","DOI":"10.1038\/srep38333","article-title":"Identification and functional analysis of long intergenic noncoding RNA genes in porcine pre-implantation embryonic development","volume":"6","author":"Li","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.omtn.2021.02.016_bib27","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.15252\/embr.201642051","article-title":"A novel long intergenic noncoding RNA indispensable for the cleavage of mouse two-cell embryos","volume":"17","author":"Wang","year":"2016","journal-title":"EMBO Rep."},{"key":"10.1016\/j.omtn.2021.02.016_bib28","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1016\/j.cell.2018.11.039","article-title":"Asymmetric Expression of LincGET Biases Cell Fate in Two-Cell Mouse Embryos","volume":"175","author":"Wang","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib29","doi-asserted-by":"crossref","first-page":"20621","DOI":"10.1073\/pnas.1112664108","article-title":"RNAi-mediated knockdown of Xist can rescue the impaired postimplantation development of cloned mouse embryos","volume":"108","author":"Matoba","year":"2011","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.omtn.2021.02.016_bib30","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1126\/science.1194174","article-title":"Impeding Xist expression from the active X chromosome improves mouse somatic cell nuclear transfer","volume":"330","author":"Inoue","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.omtn.2021.02.016_bib31","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.stemcr.2017.12.015","article-title":"XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer","volume":"10","author":"Ruan","year":"2018","journal-title":"Stem Cell Reports"},{"key":"10.1016\/j.omtn.2021.02.016_bib32","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.stem.2014.11.005","article-title":"Single-cell transcriptome analysis reveals dynamic changes in lncRNA expression during reprogramming","volume":"16","author":"Kim","year":"2015","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.omtn.2021.02.016_bib33","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1095\/biolreprod.104.029462","article-title":"Aberrant gene expression in organs of bovine clones that die within two days after birth","volume":"72","author":"Li","year":"2005","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.omtn.2021.02.016_bib34","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1016\/j.ijbiomac.2020.02.026","article-title":"RNA sequencing revealed the abnormal transcriptional profile in cloned bovine embryos","volume":"150","author":"Zhang","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.omtn.2021.02.016_bib35","first-page":"580367","article-title":"YTHDF2 Regulates Maternal Transcriptome Degradation and Embryo Development in Goat. Front. Cell","volume":"8","author":"Deng","year":"2020","journal-title":"Dev. Biol"},{"key":"10.1016\/j.omtn.2021.02.016_bib36","doi-asserted-by":"crossref","first-page":"16010","DOI":"10.1038\/celldisc.2016.10","article-title":"Identification of key factors conquering developmental arrest of somatic cell cloned embryos by combining embryo biopsy and single-cell sequencing","volume":"2","author":"Liu","year":"2016","journal-title":"Cell Discov."},{"key":"10.1016\/j.omtn.2021.02.016_bib37","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1530\/REP-15-0338","article-title":"Histone H3 lysine 27 trimethylation acts as an epigenetic barrier in porcine nuclear reprogramming","volume":"151","author":"Xie","year":"2016","journal-title":"Reproduction"},{"key":"10.1016\/j.omtn.2021.02.016_bib38","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1096\/fj.201900578RR","article-title":"Transcriptional memory inherited from donor cells is a developmental defect of bovine cloned embryos","volume":"34","author":"Zhou","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.omtn.2021.02.016_bib39","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1038\/emboj.2011.91","article-title":"KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription","volume":"30","author":"Xie","year":"2011","journal-title":"EMBO J."},{"key":"10.1016\/j.omtn.2021.02.016_bib40","doi-asserted-by":"crossref","DOI":"10.1186\/s12864-018-5021-2","article-title":"Long non-coding RNAs potentially function synergistically in the cellular reprogramming of SCNT embryos","volume":"19","author":"Wu","year":"2018","journal-title":"BMC Genomics"},{"key":"10.1016\/j.omtn.2021.02.016_bib41","doi-asserted-by":"crossref","first-page":"2813","DOI":"10.1242\/dev.107276","article-title":"Initiation of Hippo signaling is linked to polarity rather than to cell position in the pre-implantation mouse embryo","volume":"141","author":"Anani","year":"2014","journal-title":"Development"},{"key":"10.1016\/j.omtn.2021.02.016_bib42","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.cub.2013.05.044","article-title":"The Hippo pathway member Nf2 is required for inner cell mass specification","volume":"23","author":"Cockburn","year":"2013","journal-title":"Curr. Biol."},{"key":"10.1016\/j.omtn.2021.02.016_bib43","doi-asserted-by":"crossref","first-page":"e55102","DOI":"10.7554\/eLife.55102","article-title":"The S-phase-induced lncRNA SUNO1 promotes cell proliferation by controlling YAP1\/Hippo signaling pathway","volume":"9","author":"Hao","year":"2020","journal-title":"eLife"},{"key":"10.1016\/j.omtn.2021.02.016_bib44","doi-asserted-by":"crossref","first-page":"dev166587","DOI":"10.1242\/dev.166587","article-title":"Maternal Ybx1 safeguards zebrafish oocyte maturation and maternal-to-zygotic transition by repressing global translation","volume":"145","author":"Sun","year":"2018","journal-title":"Development"},{"key":"10.1016\/j.omtn.2021.02.016_bib45","doi-asserted-by":"crossref","first-page":"161","DOI":"10.7150\/ijbs.2.161","article-title":"Murine Wee1 plays a critical role in cell cycle regulation and pre-implantation stages of embryonic development","volume":"2","author":"Tominaga","year":"2006","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.omtn.2021.02.016_bib46","doi-asserted-by":"crossref","first-page":"3950","DOI":"10.1242\/dev.082024","article-title":"Klf4 is required for germ-layer differentiation and body axis patterning during Xenopus embryogenesis","volume":"139","author":"Cao","year":"2012","journal-title":"Development"},{"key":"10.1016\/j.omtn.2021.02.016_bib47","doi-asserted-by":"crossref","first-page":"e46240","DOI":"10.15252\/embr.201846240","article-title":"KDM6A and KDM6B play contrasting roles in nuclear transfer embryos revealed by MERVL reporter system","volume":"19","author":"Yang","year":"2018","journal-title":"EMBO Rep."},{"key":"10.1016\/j.omtn.2021.02.016_bib48","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1095\/biolreprod.114.122762","article-title":"Impairment of preimplantation porcine embryo development by histone demethylase KDM5B knockdown through disturbance of bivalent H3K4me3-H3K27me3 modifications","volume":"92","author":"Huang","year":"2015","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.omtn.2021.02.016_bib49","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1038\/s41556-019-0311-8","article-title":"Cellular functions of long noncoding RNAs","volume":"21","author":"Yao","year":"2019","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.omtn.2021.02.016_bib50","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.theriogenology.2020.02.036","article-title":"Aberrant DNA and histone methylation during zygotic genome activation in goat cloned embryos","volume":"148","author":"Deng","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.omtn.2021.02.016_bib51","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.theriogenology.2020.07.008","article-title":"DNA methylation dynamics during zygotic genome activation in goat","volume":"156","author":"Deng","year":"2020","journal-title":"Theriogenology"},{"key":"10.1016\/j.omtn.2021.02.016_bib52","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1101\/gad.17446611","article-title":"Integrative annotation of human large intergenic noncoding RNAs reveals global properties and specific subclasses","volume":"25","author":"Cabili","year":"2011","journal-title":"Genes Dev."},{"key":"10.1016\/j.omtn.2021.02.016_bib53","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.theriogenology.2020.06.013","article-title":"EZH2 expression and its role in spermatogonial stem cell self-renewal in goats","volume":"155","author":"Cai","year":"2020","journal-title":"Theriogenology"}],"container-title":["Molecular Therapy Nucleic Acids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2162253121000512?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2162253121000512?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T16:46:55Z","timestamp":1788540415000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2162253121000512"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":53,"alternative-id":["S2162253121000512"],"URL":"https:\/\/doi.org\/10.1016\/j.omtn.2021.02.016","relation":{},"ISSN":["2162-2531"],"issn-type":[{"value":"2162-2531","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Long non-coding RNA lnc_3712 impedes nuclear reprogramming via repressing Kdm5b","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy Nucleic Acids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.omtn.2021.02.016","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 The Authors.","name":"copyright","label":"Copyright"}]}}