{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T13:06:58Z","timestamp":1790255218694,"version":"4.1.0"},"reference-count":57,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000781","name":"European Research Council","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000781","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013840","name":"Biocenter Finland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100013840","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004012","name":"Jane ja Aatos Erkon S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","award":["4705796"],"award-info":[{"award-number":["4705796"]}],"id":[{"id":"10.13039\/501100004012","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003125","name":"Finnish Cultural Foundation","doi-asserted-by":"publisher","award":["681219"],"award-info":[{"award-number":["681219"]}],"id":[{"id":"10.13039\/501100003125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010116","name":"Medicinska Underst\u00f6dsf\u00f6reningen Liv och H\u00e4lsa","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010116","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007436","name":"Erling-Perssons Stiftelse","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007436","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004155","name":"Magnus Ehrnroothin S\u00e4\u00e4ti\u00f6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004155","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003127","name":"Punainen Risti Veripalvelu","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003127","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020412","name":"Humanitas Research Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020412","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015735","name":"Helsinki Institute of Life Science, Helsingin Yliopisto","doi-asserted-by":"publisher","award":["797011004"],"award-info":[{"award-number":["797011004"]}],"id":[{"id":"10.13039\/100015735","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010711","name":"Cancer Foundation Finland","doi-asserted-by":"publisher","award":["4706116"],"award-info":[{"award-number":["4706116"]}],"id":[{"id":"10.13039\/501100010711","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","award":["2019-04830"],"award-info":[{"award-number":["2019-04830"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002794","name":"Cancerfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002341","name":"Research Council of Finland","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002341","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Molecular Therapy Oncology"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.omton.2026.201247","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T15:28:53Z","timestamp":1780068533000},"page":"201247","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Patient-derived tumor organoids for personalized cancer immunotherapy: An immunopeptidome-to-validation approach in RCC and BC"],"prefix":"10.1016","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9388-8632","authenticated-orcid":false,"given":"Gabriella","family":"Antignani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela","family":"Feodoroff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacopo","family":"Chiaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Feola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvatore","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Firas","family":"Hamdan Hissaoui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manlio","family":"Fusciello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federica","family":"D\u2019Alessio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Bottega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yvonne","family":"Giannoula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milda","family":"Sakalauskaite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janita","family":"Sandberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miska","family":"Kosonen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virpi","family":"Stigzelius","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara J.","family":"Luck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valentina","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniele","family":"Ciampi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Haapala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui Mamede","family":"Branca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jukka","family":"Partanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satu","family":"Koskela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Rescigno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiina","family":"Sikanen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janne","family":"Lehti\u00f6","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Ndika","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Otto K.","family":"Kari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vilja M.","family":"Pieti\u00e4inen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikaela","family":"Gr\u00f6nholm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4901-3796","authenticated-orcid":false,"given":"Vincenzo","family":"Cerullo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.omton.2026.201247_bib1","first-page":"379","article-title":"Preclinical models for development of immune-oncology therapies","volume":"3","author":"Wang","year":"2022","journal-title":"Immuno-oncol Insights"},{"key":"10.1016\/j.omton.2026.201247_bib2","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1158\/0008-5472.CAN-20-4026","article-title":"Patient-Derived Organoids for Precision Cancer Immunotherapy","volume":"81","author":"Gr\u00f6nholm","year":"2021","journal-title":"Cancer Res."},{"key":"10.1016\/j.omton.2026.201247_bib3","first-page":"910","article-title":"2D and 3D cell cultures - a comparison of different types of cancer cell cultures","volume":"14","author":"Kapa\u0142czy\u0144ska","year":"2018","journal-title":"Arch. Med. Sci."},{"key":"10.1016\/j.omton.2026.201247_bib4","doi-asserted-by":"crossref","first-page":"139","DOI":"10.3390\/cancers15010139","article-title":"Role of Patient-Derived Models of Cancer in Translational Oncology","volume":"15","author":"Idrisova","year":"2022","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.omton.2026.201247_bib5","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1038\/nature07935","article-title":"Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche","volume":"459","author":"Sato","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.omton.2026.201247_bib6","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1016\/j.cell.2017.11.010","article-title":"A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity","volume":"172","author":"Sachs","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.omton.2026.201247_bib7","article-title":"Patient-Derived Tumor Organoids: New Progress and Opportunities to Facilitate Precision Cancer Immunotherapy","volume":"12","author":"Wang","year":"2022","journal-title":"Front. Oncol."},{"key":"10.1016\/j.omton.2026.201247_bib8","doi-asserted-by":"crossref","DOI":"10.3390\/ijms241914609","article-title":"Exploring Tumor\u2013Immune Interactions in Co-Culture Models of T Cells and Tumor Organoids Derived from Patients","volume":"24","author":"Jeong","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.omton.2026.201247_bib9","article-title":"Identifying tumor antigens and immune subtypes of renal cell carcinoma for immunotherapy development","volume":"13","author":"Chen","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.omton.2026.201247_bib10","doi-asserted-by":"crossref","DOI":"10.37349\/etat.2025.1002288","article-title":"Neoantigen immunotherapy: a novel treatment for bladder cancer","volume":"6","author":"Lv","year":"2025","journal-title":"Explor Target Antitumor Ther."},{"key":"10.1016\/j.omton.2026.201247_bib11","doi-asserted-by":"crossref","first-page":"635","DOI":"10.6004\/jnccn.2009.0044","article-title":"Optimal management of localized renal cell carcinoma: surgery, ablation, or active surveillance","volume":"7","author":"Chen","year":"2009","journal-title":"J. Natl. Compr. Canc. Netw."},{"key":"10.1016\/j.omton.2026.201247_bib12","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1056\/NEJMe2402364","article-title":"Adjuvant Immunotherapy for Kidney Cancer - A New Strategy with New Challenges","volume":"390","author":"Voss","year":"2024","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.omton.2026.201247_bib13","doi-asserted-by":"crossref","first-page":"269","DOI":"10.21037\/atm.2020.02.81","article-title":"Tumor mutational burden and immune signatures interplay in renal cell carcinoma","volume":"8","author":"Yakirevich","year":"2020","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.omton.2026.201247_bib14","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1038\/s41581-020-0316-3","article-title":"The immunology of renal cell carcinoma","volume":"16","author":"D\u00edaz-Montero","year":"2020","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.omton.2026.201247_bib15","doi-asserted-by":"crossref","first-page":"1793","DOI":"10.3390\/nu16111793","article-title":"Association of Pro-Inflammatory Diet, Smoking, and Alcohol Consumption with Bladder Cancer: Evidence from Case-Control and NHANES Studies from 1999 to 2020","volume":"16","author":"Teng","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.omton.2026.201247_bib16","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1002\/path.5306","article-title":"Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approaches","volume":"249","author":"Song","year":"2019","journal-title":"J. Pathol."},{"key":"10.1016\/j.omton.2026.201247_bib17","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1038\/s41420-024-01883-x","article-title":"Molecular profiling of a bladder cancer with very high tumour mutational burden","volume":"10","author":"Scimeca","year":"2024","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.omton.2026.201247_bib18","doi-asserted-by":"crossref","first-page":"15992","DOI":"10.1021\/acsnano.1c04371","article-title":"PeptiCHIP: A Microfluidic Platform for Tumor Antigen Landscape Identification","volume":"15","author":"Feola","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.omton.2026.201247_bib19","doi-asserted-by":"crossref","first-page":"7056","DOI":"10.1038\/s41467-023-42668-7","article-title":"Development of mesothelioma-specific oncolytic immunotherapy enabled by immunopeptidomics of murine and human mesothelioma tumors","volume":"14","author":"Chiaro","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.omton.2026.201247_bib20","doi-asserted-by":"crossref","DOI":"10.1002\/cti2.1248","article-title":"Patient-derived organoids of bladder cancer recapitulate antigen expression profiles and serve as a personal evaluation model for CAR-T cells in vitro","volume":"10","author":"Yu","year":"2021","journal-title":"Clin. Transl. Immunology"},{"key":"10.1016\/j.omton.2026.201247_bib21","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.cell.2018.03.017","article-title":"Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer","volume":"173","author":"Lee","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.omton.2026.201247_bib22","doi-asserted-by":"crossref","first-page":"1808","DOI":"10.1158\/2159-8290.CD-20-0522","article-title":"Tumor Mutational Burden as a Predictive Biomarker in Solid Tumors","volume":"10","author":"Sha","year":"2020","journal-title":"Cancer Discov."},{"key":"10.1016\/j.omton.2026.201247_bib23","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12935-018-0661-5","article-title":"Somatic mutations in renal cell carcinomas from Chinese patients revealed by whole exome sequencing","volume":"18","author":"Wang","year":"2018","journal-title":"Cancer Cell Int."},{"key":"10.1016\/j.omton.2026.201247_bib24","doi-asserted-by":"crossref","first-page":"4476","DOI":"10.1158\/0008-5472.CAN-20-0977","article-title":"Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer","volume":"80","author":"Bellmunt","year":"2020","journal-title":"Cancer Res."},{"key":"10.1016\/j.omton.2026.201247_bib25","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.ajhg.2017.01.004","article-title":"InterVar: Clinical Interpretation of Genetic Variants by the 2015 ACMG-AMP Guidelines","volume":"100","author":"Li","year":"2017","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.omton.2026.201247_bib26","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1093\/bioinformatics\/btx817","article-title":"Personal Cancer Genome Reporter: variant interpretation report for precision oncology","volume":"34","author":"Nakken","year":"2018","journal-title":"Bioinformatics"},{"key":"10.1016\/j.omton.2026.201247_bib27","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.4049\/jimmunol.1501721","article-title":"The Length Distribution of Class I-Restricted T Cell Epitopes Is Determined by Both Peptide Supply and MHC Allele-Specific Binding Preference","volume":"196","author":"Trolle","year":"2016","journal-title":"J. Immunol."},{"key":"10.1016\/j.omton.2026.201247_bib28","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1038\/nature24462","article-title":"Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer","volume":"551","author":"Balachandran","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.omton.2026.201247_bib29","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1158\/2326-6066.CIR-20-0814","article-title":"Viral Molecular Mimicry Influences the Antitumor Immune Response in Murine and Human Melanoma","volume":"9","author":"Chiaro","year":"2021","journal-title":"Cancer Immunol. Res."},{"key":"10.1016\/j.omton.2026.201247_bib30","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms13404","article-title":"Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry","volume":"7","author":"Bassani-Sternberg","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.omton.2026.201247_bib31","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2024.2407532","article-title":"Enhancing T-cell recruitment in renal cell carcinoma with cytokine-armed adenoviruses","volume":"13","author":"Feodoroff","year":"2024","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.omton.2026.201247_bib32","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1186\/s12943-025-02374-y","article-title":"Establishing 3D organoid models from patient-derived conditionally reprogrammed cells to bridge preclinical and clinical insights in pancreatic cancer","volume":"24","author":"Kim","year":"2025","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.omton.2026.201247_bib33","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13578-022-00775-w","article-title":"3D and organoid culture in research: physiology, hereditary genetic diseases and cancer","volume":"12","author":"Suarez-Martinez","year":"2022","journal-title":"Cell Biosci."},{"key":"10.1016\/j.omton.2026.201247_bib34","article-title":"Vimentin promotes collective cell migration through collagen networks via increased matrix remodeling and spheroid fluidity","author":"Ho Thanh","year":"2024","journal-title":"bioRxiv"},{"key":"10.1016\/j.omton.2026.201247_bib35","article-title":"Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors","volume":"9","author":"Wang","year":"2022","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.omton.2026.201247_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2490-11-1","article-title":"Quantification of HLA class I molecules on renal cell carcinoma using Edman degradation","volume":"11","author":"Stickel","year":"2011","journal-title":"BMC Urol."},{"key":"10.1016\/j.omton.2026.201247_bib37","doi-asserted-by":"crossref","first-page":"e002071","DOI":"10.1136\/jitc-2020-002071","article-title":"HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy","volume":"9","author":"Marcu","year":"2021","journal-title":"J. Immunother. Cancer"},{"key":"10.1016\/j.omton.2026.201247_bib38","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1021\/pr9006365","article-title":"Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry","volume":"9","author":"Tabb","year":"2010","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.omton.2026.201247_bib39","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1074\/mcp.TIR117.000383","article-title":"High-throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferon\u03b3-Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome","volume":"17","author":"Chong","year":"2018","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.omton.2026.201247_bib40","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13073-020-00731-8","article-title":"Integrative -omics and HLA-ligandomics analysis to identify novel drug targets for ccRCC immunotherapy","volume":"12","author":"Reustle","year":"2020","journal-title":"Genome Med."},{"key":"10.1016\/j.omton.2026.201247_bib41","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/1097-0142(20000701)89:1<152::AID-CNCR20>3.0.CO;2-T","article-title":"Increased glyceraldehyde-3-phosphate dehydrogenase expression in renal cell carcinoma identified by RNA-based, arbitrarily primed polymerase chain reaction","volume":"89","author":"Vil\u00e0","year":"2000","journal-title":"Cancer"},{"key":"10.1016\/j.omton.2026.201247_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7150\/ijbs.77181","article-title":"Vimentin epigenetic deregulation in Bladder Cancer associates with acquisition of invasive and metastatic phenotype through epithelial-to-mesenchymal transition","volume":"19","author":"Monteiro-Reis","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.omton.2026.201247_bib43","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s12094-014-1199-1","article-title":"Expression of vimentin and survivin in clear cell renal cell carcinoma and correlation with p53","volume":"17","author":"Shi","year":"2015","journal-title":"Clin. Transl. Oncol."},{"key":"10.1016\/j.omton.2026.201247_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.686547","article-title":"RPL19 Is a Prognostic Biomarker and Promotes Tumor Progression in Hepatocellular Carcinoma","volume":"9","author":"Rao","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.omton.2026.201247_bib45","article-title":"PLIN2 Promotes Lipid Accumulation in Ascites-Associated Macrophages and Ovarian Cancer Progression by HIF1\u03b1\/SPP1 Signaling","volume":"12","author":"Luo","year":"2025","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.omton.2026.201247_bib46","doi-asserted-by":"crossref","first-page":"4081","DOI":"10.2147\/OTT.S198341","article-title":"ODC1 promotes proliferation and mobility via the AKT\/GSK3\u03b2\/\u03b2-catenin pathway and modulation of acidotic microenvironment in human hepatocellular carcinoma","volume":"12","author":"Ye","year":"2019","journal-title":"OncoTargets Ther."},{"key":"10.1016\/j.omton.2026.201247_bib47","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/s11658-024-00674-7","article-title":"Elongation factor 2 in cancer: a promising therapeutic target in protein translation","volume":"29","author":"Jia","year":"2024","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.omton.2026.201247_bib48","doi-asserted-by":"crossref","first-page":"3506","DOI":"10.3390\/cancers17213506","article-title":"Antigenic Dark Matter: Unexplored Post-Translational Modifications of Tumor-Associated and Tumor-Specific Antigens in Pancreatic Cancer","volume":"17","author":"Safa","year":"2025","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.omton.2026.201247_bib49","doi-asserted-by":"crossref","first-page":"2345","DOI":"10.1158\/2767-9764.CRC-23-0121","article-title":"Multifactorial Remodeling of the Cancer Immunopeptidome by IFN\u03b3","volume":"3","author":"Newey","year":"2023","journal-title":"Cancer Res. Commun."},{"key":"10.1016\/j.omton.2026.201247_bib50","doi-asserted-by":"crossref","first-page":"141","DOI":"10.3389\/fimmu.2019.00141","article-title":"Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression","volume":"10","author":"Javitt","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.omton.2026.201247_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.smim.2023.101727","article-title":"The impact of immunopeptidomics: From basic research to clinical implementation","volume":"66","author":"Shapiro","year":"2023","journal-title":"Semin. Immunol."},{"key":"10.1016\/j.omton.2026.201247_bib52","doi-asserted-by":"crossref","DOI":"10.1080\/2162402X.2015.1105429","article-title":"Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the antitumor immunity and efficacy against melanoma","volume":"5","author":"Capasso","year":"2016","journal-title":"Oncoimmunology"},{"key":"10.1016\/j.omton.2026.201247_bib53","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/978-1-4939-7537-2_14","article-title":"Mass Spectrometry Based Immunopeptidomics for the Discovery of Cancer Neoantigens","volume":"1719","author":"Bassani-Sternberg","year":"2018","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.omton.2026.201247_bib54","doi-asserted-by":"crossref","first-page":"7472","DOI":"10.1038\/s41467-023-42692-7","article-title":"TOF(IMS) mass spectrometry-based immunopeptidomics refines tumor antigen identification","volume":"14","author":"Hoenisch Gravel","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.omton.2026.201247_bib55","doi-asserted-by":"crossref","first-page":"3876","DOI":"10.1021\/acs.jproteome.9b00313","article-title":"MHCquant: Automated and Reproducible Data Analysis for Immunopeptidomics","volume":"18","author":"Bichmann","year":"2019","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.omton.2026.201247_bib56","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.109312","article-title":"Identification of a class of non-conventional ER-stress-response-derived immunogenic peptides","volume":"36","author":"Melacarne","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.omton.2026.201247_bib57","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1016\/j.ccell.2023.08.014","article-title":"Sensitizing cancer cells to immune checkpoint inhibitors by microbiota-mediated upregulation of HLA class I","volume":"41","author":"Ferrari","year":"2023","journal-title":"Cancer Cell"}],"container-title":["Molecular Therapy Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950329926001232?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2950329926001232?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:42:11Z","timestamp":1790253731000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2950329926001232"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":57,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,9]]}},"alternative-id":["S2950329926001232"],"URL":"https:\/\/doi.org\/10.1016\/j.omton.2026.201247","relation":{},"ISSN":["2950-3299"],"issn-type":[{"value":"2950-3299","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Patient-derived tumor organoids for personalized cancer immunotherapy: An immunopeptidome-to-validation approach in RCC and BC","name":"articletitle","label":"Article Title"},{"value":"Molecular Therapy Oncology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.omton.2026.201247","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc. on behalf of The American Society of Gene and Cell Therapy.","name":"copyright","label":"Copyright"}],"article-number":"201247"}}