{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:52:40Z","timestamp":1792813960070,"version":"4.5.0"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T00:00:00Z","timestamp":1744588800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["One Health"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.onehlt.2025.101040","type":"journal-article","created":{"date-parts":[[2025,4,21]],"date-time":"2025-04-21T19:19:06Z","timestamp":1745263146000},"page":"101040","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Re-emergence of Crimean Congo hemorrhagic fever virus in Kedougou, south-eastern Senegal in 2023: Epidemiological and zoological investigations of the first symptomatic human case"],"prefix":"10.1016","volume":"20","author":[{"given":"Bacary Djilocalisse","family":"Sadio","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dethi\u00e9","family":"Ngom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bocar","family":"Sow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheikh Tidiane","family":"Diagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aboubacry","family":"Gaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aliou","family":"Khoul\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ousseynou","family":"S\u00e8ne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Faye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moufid","family":"Mhamadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diogop","family":"Camara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cherif Nehma","family":"Sylla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatoumata Goundo","family":"Diaby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahfouz","family":"Traor\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oumar","family":"Ndiaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalifa Ababacar","family":"Mbaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khady","family":"Ciss\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boly","family":"Diop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El Hadji Mamadou","family":"Ndiaye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoro","family":"Sall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alassane","family":"Mbengue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdourahmane","family":"Sow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amadou Alpha","family":"Sall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oumar","family":"Faye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Faye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ndongo","family":"Dia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mawlouth","family":"Diallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moussa Moise","family":"Diagne","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gamou","family":"Fall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diawo","family":"Diallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.onehlt.2025.101040_bb0005","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.antiviral.2004.08.001","article-title":"Crimean\u2013Congo hemorrhagic fever","volume":"64","author":"Whitehouse","year":"2004","journal-title":"Antiviral Res."},{"key":"10.1016\/j.onehlt.2025.101040_bb0010","author":"T.V.D. Societies, International Committee on Taxonomy of Viruses (ICTV)"},{"key":"10.1016\/j.onehlt.2025.101040_bb0015","author":"Vourc'h"},{"key":"10.1016\/j.onehlt.2025.101040_bb0020","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.antiviral.2016.06.011","article-title":"Prognostic factors, pathophysiology and novel biomarkers in Crimean-Congo hemorrhagic fever","volume":"132","author":"Akinci","year":"2016","journal-title":"Antiviral Res."},{"key":"10.1016\/j.onehlt.2025.101040_bb0025","doi-asserted-by":"crossref","first-page":"7766","DOI":"10.1128\/JVI.02469-10","article-title":"Crimean-Congo hemorrhagic fever virus activates endothelial cells","volume":"85","author":"Connolly-Andersen","year":"2011","journal-title":"J. Virol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0030","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.antiviral.2013.07.006","article-title":"Crimean-Congo hemorrhagic fever: history, epidemiology, pathogenesis, clinical syndrome and genetic diversity","volume":"100","author":"Bente","year":"2013","journal-title":"Antiviral Res."},{"key":"10.1016\/j.onehlt.2025.101040_bb0035","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.antiviral.2017.11.019","article-title":"Second international conference on Crimean-Congo hemorrhagic fever","volume":"150","author":"Spengler","year":"2018","journal-title":"Antiviral Res."},{"key":"10.1016\/j.onehlt.2025.101040_bb0040","doi-asserted-by":"crossref","first-page":"1513123","DOI":"10.3389\/fvets.2024.1513123","article-title":"Crimean-Congo haemorrhagic fever virus in ticks, domestic, and wild animals","volume":"11","author":"Celina","year":"2025","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.onehlt.2025.101040_bb0045","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.antiviral.2016.07.010","article-title":"Multi-center prospective evaluation of discharge criteria for hospitalized patients with Crimean-Congo Hemorrhagic Fever","volume":"133","author":"Leblebicioglu","year":"2016","journal-title":"Antiviral Res."},{"key":"10.1016\/j.onehlt.2025.101040_bb0050","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.cimid.2007.07.001","article-title":"Recent progress in molecular biology of Crimean\u2013Congo hemorrhagic fever","volume":"30","author":"Morikawa","year":"2007","journal-title":"Comp. Immunol. Microbiol. Infect. Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0055","doi-asserted-by":"crossref","first-page":"317","DOI":"10.3390\/tropicalmed8060317","article-title":"Detection of Crimean\u2013Congo haemorrhagic fever virus from livestock ticks in Northern, Central and Southern Senegal in 2021","volume":"8","author":"Badji","year":"2023","journal-title":"Trop. Med. Infect. Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0060","article-title":"History and classification of Aigai virus (formerly Crimean\u2013Congo haemorrhagic fever virus genotype VI)","volume":"103","author":"Papa","year":"2022","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0065","doi-asserted-by":"crossref","first-page":"315","DOI":"10.3390\/v16020315","article-title":"Emergence of Crimean\u2013Congo hemorrhagic fever virus in Eastern Senegal in 2022","volume":"16","author":"Sene","year":"2024","journal-title":"Viruses"},{"key":"10.1016\/j.onehlt.2025.101040_bb0070","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1309\/LMN1P2FRZ7BKZSCO","article-title":"Crimean-Congo hemorrhagic fever","volume":"46","author":"Shayan","year":"2015","journal-title":"Lab. Med."},{"key":"10.1016\/j.onehlt.2025.101040_bb0075","doi-asserted-by":"crossref","first-page":"1907","DOI":"10.3390\/microorganisms9091907","article-title":"Crimean-Congo hemorrhagic fever virus in Asia, Africa and Europe","volume":"9","author":"Shahhosseini","year":"2021","journal-title":"Microorganisms"},{"key":"10.1016\/j.onehlt.2025.101040_bb0080","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.antiviral.2015.05.005","article-title":"Meeting report: first international conference on Crimean-Congo hemorrhagic fever","volume":"120","author":"Papa","year":"2015","journal-title":"Antiviral Res."},{"key":"10.1016\/j.onehlt.2025.101040_bb0085","unstructured":"J.-P. Digoutte, Le virus de la fi\u00e8vre h\u00e9morragique de Crim\u00e9e-Congo (CCHF) en Mauritanie w, (n.d.). https:\/\/horizon.documentation.ird.fr\/exl-doc\/pleins_textes\/cahiers\/entomo\/23244.pdf (accessed March 7, 2024)."},{"key":"10.1016\/j.onehlt.2025.101040_bb0090","series-title":"Mater. 16, Nauchn. Sess. Inst. Polio. Virus. Entsefalitov (Moscow 2 (1969))","first-page":"158","article-title":"Results from investigating human and domestic and wild animal blood sera in the S\u00e9n\u00e9gal Republic (western Africa) for antibodies to Crimean hemorrhagic fever virus","author":"Chunikhin","year":"1969"},{"key":"10.1016\/j.onehlt.2025.101040_bb0095","article-title":"Crimean-Congo haemorrhagic fever outbreak in Northern Senegal in 2022: Prevalence of the virus in livestock and ticks, associated risk factors and epidemiological implications","author":"Ngom","year":"2025","journal-title":"Zoo. Public Health"},{"key":"10.1016\/j.onehlt.2025.101040_bb0100","series-title":"Bulletin hebdomadaire des urgences infectieuses de sant\u00e9 publique au S\u00e9n\u00e9gal","author":"Ba","year":"2023"},{"key":"10.1016\/j.onehlt.2025.101040_bb0105","author":"Perez"},{"key":"10.1016\/j.onehlt.2025.101040_bb0110","series-title":"African Ixodoidea","author":"Hoogstraal","year":"1956"},{"key":"10.1016\/j.onehlt.2025.101040_bb0115","series-title":"Tiks of Dometic Animals in Africa: a guide to identification of Species","first-page":"221","author":"Walker","year":"2003"},{"key":"10.1016\/j.onehlt.2025.101040_bb0120","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/j.1365-2028.1973.tb00081.x","article-title":"A review of the age determination of mammals by means of teeth, with especial reference to Africa","volume":"11","author":"Spinage","year":"1973","journal-title":"Afr. J. Ecol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0125","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1128\/jcm.19.2.225-229.1984","article-title":"Detection of human immunoglobulins G and M antibodies to Rift Valley fever virus by enzyme-linked immunosorbent assay","volume":"19","author":"Niklasson","year":"1984","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0130","series-title":"Camicas, Epidemiology of Crimean-Congo Hemorrhagic Fever in Senegal: Temporal and Spatial Patterns","first-page":"323","author":"Wilson","year":"1991"},{"key":"10.1016\/j.onehlt.2025.101040_bb0135","doi-asserted-by":"crossref","first-page":"922","DOI":"10.1128\/jcm.25.5.922-924.1987","article-title":"Rapid diagnosis of human Crimean-Congo hemorrhagic fever and detection of the virus in naturally infected ticks","volume":"25","author":"Saluzzo","year":"1987","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0140","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.antiviral.2018.01.006","article-title":"A novel double-antigen sandwich ELISA for the species-independent detection of Crimean-Congo hemorrhagic fever virus-specific antibodies","volume":"151","author":"Sas","year":"2018","journal-title":"Antiviral Res."},{"key":"10.1016\/j.onehlt.2025.101040_bb0145","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1093\/infdis\/jiy362","article-title":"Development of mobile laboratory for viral hemorrhagic fever detection in Africa","volume":"218","author":"Weidmann","year":"2018","journal-title":"J Infect Dis"},{"key":"10.1016\/j.onehlt.2025.101040_bb0150","doi-asserted-by":"crossref","first-page":"ofab655","DOI":"10.1093\/ofid\/ofab655","article-title":"Detection of Rift Valley fever virus lineage H from South Africa through the syndromic sentinel surveillance network in Senegal","volume":"9","author":"Bob","year":"2022","journal-title":"Open Forum Infect. Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0155","series-title":"R: A language and environment for statistical computing","first-page":"2020","author":"R.C. Team","year":"2020"},{"key":"10.1016\/j.onehlt.2025.101040_bb0160","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1002\/jmv.24990","article-title":"Dynamics of viral load in Crimean Congo hemorrhagic fever","volume":"90","author":"Hasanoglu","year":"2018","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0165","doi-asserted-by":"crossref","first-page":"1498672","DOI":"10.3389\/fviro.2024.1498672","article-title":"Case report: kinetics of viral load, immunoglobulins, and cytokines in a fatal case of Crimean-Congo hemorrhagic fever virus","volume":"4","author":"Mhamadi","year":"2025","journal-title":"Front. Virol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0170","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.ijregi.2023.03.016","article-title":"Seroprevalence of Crimean-Congo hemorrhagic fever virus and Rift Valley fever virus in human population in Senegal from October to November 2020","volume":"7","author":"Sankhe","year":"2023","journal-title":"IJID Regions"},{"key":"10.1016\/j.onehlt.2025.101040_bb0175","doi-asserted-by":"crossref","first-page":"557","DOI":"10.4269\/ajtmh.1990.43.557","article-title":"Distribution of Crimean-Congo hemorrhagic fever viral antibody in Senegal: environmental and vectorial correlates","volume":"43","author":"Wilson","year":"1990","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1016\/j.onehlt.2025.101040_bb0180","article-title":"Fi\u00e8vres h\u00e9morragiques virales au Mali\u00a0: Revue des travaux publi\u00e9s sur les virus de Lassa, Crim\u00e9e Congo, Ebola, Fi\u00e8vre de la Vall\u00e9e du Rift et Dengue","volume":"2","author":"Bane","year":"2018","journal-title":"Rev. Malienne d\u2019Infectiol. Microbiol."},{"key":"10.1016\/j.onehlt.2025.101040_bb0185","doi-asserted-by":"crossref","first-page":"17878","DOI":"10.1038\/s41598-022-22491-8","article-title":"First hepatitis E outbreak in southeastern Senegal","volume":"12","author":"Sadio","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.onehlt.2025.101040_bb0190","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.3201\/eid1010.040586","article-title":"Human Crimean-Congo hemorrhagic fever, S\u00e9n\u00e9gal","volume":"10","author":"Nabeth","year":"2004","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0195","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1080\/22221751.2020.1847605","article-title":"Detection of Crimean Congo haemorrhagic fever virus in North-eastern Senegal, Bokidiaw\u00e9 2019","volume":"9","author":"Dieng","year":"2020","journal-title":"Emerg. Microb. Infect."},{"key":"10.1016\/j.onehlt.2025.101040_bb0200","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3390\/tropicalmed7100324","article-title":"Crimean\u2013Congo hemorrhagic fever virus survey in humans, ticks, and livestock in Agnam (Northeastern Senegal) from February 2021 to March 2022","volume":"7","author":"Mhamadi","year":"2022","journal-title":"Trop. Med. Infect. Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0205","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009228","article-title":"Crimean-Congo hemorrhagic fever virus antibody prevalence in Mauritanian livestock (cattle, goats, sheep and camels) is stratified by the animal\u2019s age","volume":"15","author":"Schulz","year":"2021","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0210","doi-asserted-by":"crossref","first-page":"2618","DOI":"10.3390\/v14122618","article-title":"Detection of Crimean-Congo hemorrhagic fever virus antibodies in cattle in Plateau State, Nigeria","volume":"14","author":"Dzikwi-Emennaa","year":"2022","journal-title":"Viruses"},{"key":"10.1016\/j.onehlt.2025.101040_bb0215","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1089\/vbz.2019.2592","article-title":"Seroprevalence of Crimean-Congo hemorrhagic fever in domesticated animals in northwestern Senegal","volume":"20","author":"Mangombi","year":"2020","journal-title":"Vector-Borne Zoonot. Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0220","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.ttbdis.2015.03.002","article-title":"Epidemiological survey of Crimean Congo hemorrhagic fever virus in cattle in East Darfur State, Sudan","volume":"6","author":"Ibrahim","year":"2015","journal-title":"Ticks Tick-Borne Dis."},{"key":"10.1016\/j.onehlt.2025.101040_bb0225","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1051\/parasite\/1999061027","article-title":"Transmission exp\u00e9rimentale du virus de la fi\u00e8vre h\u00e9morragique de Crim\u00e9e-Congo: place de trois esp\u00e8ces vectrices dans les cycles de maintenance et de transmission au S\u00e9n\u00e9gal","volume":"6","author":"Faye","year":"1999","journal-title":"Parasite"},{"key":"10.1016\/j.onehlt.2025.101040_bb0230","doi-asserted-by":"crossref","DOI":"10.1002\/vms3.70165","article-title":"Tick species infesting livestock in three bioclimatic areas of Senegal: bioecology, prevalence of tick infestation, associated categorical factors and Crimean-Congo haemorrhagic fever virus infection","volume":"11","author":"Khoule","year":"2025","journal-title":"Vet. Med. Sci."},{"key":"10.1016\/j.onehlt.2025.101040_bb0235","series-title":"Hemorrhagic Fever with Renal Syndrome, Tick- and Mosquito-Borne Viruses","first-page":"303","article-title":"Ecology of ticks as potential vectors of Crimean-Congo hemorrhagic fever virus in Senegal: epidemiological implications","author":"Camicas","year":"1990"}],"container-title":["One Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235277142500076X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235277142500076X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:41:57Z","timestamp":1765413717000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S235277142500076X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":47,"alternative-id":["S235277142500076X"],"URL":"https:\/\/doi.org\/10.1016\/j.onehlt.2025.101040","relation":{},"ISSN":["2352-7714"],"issn-type":[{"value":"2352-7714","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Re-emergence of Crimean Congo hemorrhagic fever virus in Kedougou, south-eastern Senegal in 2023: Epidemiological and zoological investigations of the first symptomatic human case","name":"articletitle","label":"Article Title"},{"value":"One Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.onehlt.2025.101040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101040"}}