{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T13:39:47Z","timestamp":1793108387778,"version":"4.5.0"},"reference-count":51,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,5,17]],"date-time":"2025-05-17T00:00:00Z","timestamp":1747440000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000943","name":"Commonwealth Scientific and Industrial Research Organisation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000943","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["One Health"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.onehlt.2025.101081","type":"journal-article","created":{"date-parts":[[2025,5,22]],"date-time":"2025-05-22T12:08:53Z","timestamp":1747915733000},"page":"101081","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["Systems thinking to understand the complexity of antimicrobial resistance across One Health: A systematic review of current approaches"],"prefix":"10.1016","volume":"20","author":[{"given":"Yen","family":"Pham","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa M.","family":"Wozniak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.onehlt.2025.101081_bb0005","article-title":"Mapping the effect of antimicrobial resistance in poultry production in Senegal: an integrated system dynamics and network analysis approach","volume":"10","author":"Aboah","year":"2023","journal-title":"Front. Veterin. Sci."},{"key":"10.1016\/j.onehlt.2025.101081_bb0010","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1093\/heapol\/czaa052","article-title":"Factors influencing non-prescription sales of antibiotics among patent and proprietary medicine vendors in Kano, Nigeria: a cross-sectional study","volume":"35","author":"Adamu","year":"2020","journal-title":"Health Policy Plan."},{"key":"10.1016\/j.onehlt.2025.101081_bb0015","doi-asserted-by":"crossref","first-page":"e291","DOI":"10.1016\/S2542-5196(23)00026-8","article-title":"Global antimicrobial-resistance drivers: an ecological country-level study at the human–animal interface","volume":"7","author":"Allel","year":"2023","journal-title":"Lancet Planetary Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0020","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1089\/omi.2023.0049","article-title":"One Health lens for antimicrobial resistance research and funding: a systematic review","volume":"27","author":"Alsamara","year":"2023","journal-title":"Omics: J. Integr. Biol."},{"key":"10.1016\/j.onehlt.2025.101081_bb0025","doi-asserted-by":"crossref","first-page":"e124","DOI":"10.1016\/S2542-5196(23)00278-4","article-title":"The need for One Health systems-thinking approaches to understand multiscale dissemination of antimicrobial resistance","volume":"8","author":"Arnold","year":"2024","journal-title":"Lancet Planetary Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0030","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1258\/0956462054679124","article-title":"Impact of an effective multidrug-resistant tuberculosis control programme in the setting of an immature HIV epidemic: system dynamics simulation model","volume":"16","author":"Atun","year":"2005","journal-title":"Int. J. STD AIDS"},{"key":"10.1016\/j.onehlt.2025.101081_bb0035","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1258\/095646207780659024","article-title":"High coverage with HAART is required to substantially reduce the number of deaths from tuberculosis: system dynamics simulation","volume":"18","author":"Atun","year":"2007","journal-title":"Int. J. STD AIDS"},{"key":"10.1016\/j.onehlt.2025.101081_bb0040","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.healthpol.2006.05.021","article-title":"Impact of joined-up HIV harm reduction and multidrug resistant tuberculosis control programmes in Estonia: system dynamics simulation model","volume":"81","author":"Atun","year":"2007","journal-title":"Health Policy"},{"key":"10.1016\/j.onehlt.2025.101081_bb0045","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.scitotenv.2019.06.134","article-title":"Identifying hotspots for antibiotic resistance emergence and selection, and elucidating pathways to human exposure: Application of a systems-thinking approach to aquaculture systems","volume":"687","author":"Brunton","year":"2019","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.onehlt.2025.101081_bb0050","series-title":"Feedback economics economic modeling with system dynamics","author":"Cavana","year":"2021"},{"key":"10.1016\/j.onehlt.2025.101081_bb0055","doi-asserted-by":"crossref","first-page":"e368","DOI":"10.1016\/S1473-3099(18)30296-2","article-title":"Quantifying drivers of antibiotic resistance in humans: a systematic review","volume":"18","author":"Chatterjee","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.onehlt.2025.101081_bb0060","author":"Climate Interactive"},{"key":"10.1016\/j.onehlt.2025.101081_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0290464","article-title":"Is scientific evidence enough? Using expert opinion to fill gaps in data in antimicrobial resistance research","volume":"18","author":"Cousins","year":"2023","journal-title":"PLoS One"},{"key":"10.1016\/j.onehlt.2025.101081_bb0070","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.envint.2007.10.010","article-title":"Causal regulations vs. political will: Why human zoonotic infections increase despite precautionary bans on animal antibiotics","volume":"34","author":"Cox","year":"2008","journal-title":"Environ. Int."},{"key":"10.1016\/j.onehlt.2025.101081_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquaculture.2021.736735","article-title":"Systems-thinking approach to identify and assess feasibility of potential interventions to reduce antibiotic use in tilapia farming in Egypt","volume":"540","author":"Desbois","year":"2021","journal-title":"Aquaculture"},{"key":"10.1016\/j.onehlt.2025.101081_bb0080","first-page":"231","article-title":"Using the kaban lakes integrated assessment model for investigating potential levels of antibiotic pollution of the Nizhniy Kaban and Sredniy Kaban Lakes","author":"Frolova","year":"2020","journal-title":"Water Air Soil Pollut."},{"key":"10.1016\/j.onehlt.2025.101081_bb0085","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1080\/09581596.2023.2210743","article-title":"Do you see the problem? Visualising a generalised \u2018complex local system\u2019 of antibiotic prescribing across the United Kingdom using qualitative interview data","volume":"33","author":"Glover","year":"2023","journal-title":"Crit. Public Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0090","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.csbj.2020.12.006","article-title":"Recent advances in exploring the heavy metal(loid) resistant microbiome","volume":"19","author":"Hao","year":"2021","journal-title":"Comput. Struct. Biotechnol. J."},{"key":"10.1016\/j.onehlt.2025.101081_bb0095","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1002\/sdr.200","article-title":"Toward a dynamic theory of antibiotic resistance","volume":"16","author":"Homer","year":"2000","journal-title":"Syst. Dyn. Rev."},{"key":"10.1016\/j.onehlt.2025.101081_bb0100","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1111\/jep.13203","article-title":"A system dynamics model of infection risk, expectations, and perceptions on antibiotic prescribing in the United States","volume":"26","author":"Kianmehr","year":"2020","journal-title":"J. Eval. Clin. Pract."},{"key":"10.1016\/j.onehlt.2025.101081_bb0105","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens10121535","article-title":"Factors associated with hiv drug resistance in dar es salaam, tanzania: analysis of a complex adaptive system","volume":"10","author":"Kiekens","year":"2021","journal-title":"Pathogens"},{"key":"10.1016\/j.onehlt.2025.101081_bb0110","doi-asserted-by":"crossref","DOI":"10.1186\/s12889-022-12738-4","article-title":"Exploring the mechanisms behind HIV drug resistance in sub-Saharan Africa: conceptual mapping of a complex adaptive system based on multi-disciplinary expert insights","volume":"22","author":"Kiekens","year":"2022","journal-title":"BMC Public Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0115","first-page":"17","article-title":"Factors influencing antimicrobial resistance in the European food system and potential leverage points for intervention: a participatory, One Health study","author":"Lambraki","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.onehlt.2025.101081_bb0120","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.992507","article-title":"Factors impacting antimicrobial resistance in the South East Asian food system and potential places to intervene: a participatory, one health study","volume":"13","author":"Lambraki","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.onehlt.2025.101081_bb0125","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/s41579-021-00649-x","article-title":"Antibiotic resistance in the environment","volume":"20","author":"Larsson","year":"2022","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.onehlt.2025.101081_bb0130","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1038\/s41564-023-01351-9","article-title":"AMR, one health and the environment","volume":"8","author":"Larsson","year":"2023","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.onehlt.2025.101081_bb0135","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1057\/jors.2009.90","article-title":"System Dynamic simulation of treatment policies to address colliding epidemics of tuberculosis, drug resistant tuberculosis and injecting drug users driven HIV in Russia","volume":"61","author":"Lebcir","year":"2010","journal-title":"J. Oper. Res. Soc."},{"key":"10.1016\/j.onehlt.2025.101081_bb0140","series-title":"Systems Thinking, System Dynamics: Managing Change and Complexity","author":"Maani","year":"2007"},{"key":"10.1016\/j.onehlt.2025.101081_bb0145","doi-asserted-by":"crossref","DOI":"10.3389\/fpubh.2022.816943","article-title":"System mapping of antimicrobial resistance to combat a rising global health crisis","volume":"10","author":"Matthiessen","year":"2022","journal-title":"Front. Public Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0150","series-title":"2. WHO Guidelines on Use of Medically Important Antimicrobials in Food-Producing Animals","article-title":"Potential unintended consequences associated with restrictions on antimicrobial use in food-producing animals","author":"Mcewen","year":"2017"},{"key":"10.1016\/j.onehlt.2025.101081_bb0155","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","author":"Murray","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.onehlt.2025.101081_bb0160","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/S0140-6736(24)01867-1","article-title":"Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050","volume":"404","author":"Naghavi","year":"2024","journal-title":"Lancet"},{"key":"10.1016\/j.onehlt.2025.101081_bb0165","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jgar.2023.12.008","article-title":"Characterising proximal and distal drivers of antimicrobial resistance: an umbrella review","volume":"36","author":"Nguyen-Thanh","year":"2024","journal-title":"J. Global Antimicrob. Resist."},{"key":"10.1016\/j.onehlt.2025.101081_bb0170","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"10.1016\/j.onehlt.2025.101081_bb0175","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1186\/1478-4505-12-51","article-title":"The application of systems thinking in health: Why use systems thinking?","volume":"12","author":"Peters","year":"2014","journal-title":"Health Res. Policy Syst."},{"key":"10.1016\/j.onehlt.2025.101081_bb0180","doi-asserted-by":"crossref","first-page":"112790","DOI":"10.1016\/j.jenvman.2021.112790","article-title":"Evaluating management strategies for sustainable crop production under changing climate conditions: a system dynamics approach","volume":"292","author":"Pham","year":"2021","journal-title":"J. Environ. Manag."},{"key":"10.1016\/j.onehlt.2025.101081_bb0185","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1080\/07294360.2013.841651","article-title":"The benefits of publishing systematic quantitative literature reviews for PhD candidates and other early-career researchers","volume":"33","author":"Pickering","year":"2014","journal-title":"High. Educ. Res. Dev."},{"key":"10.1016\/j.onehlt.2025.101081_bb0190","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1080\/03075079.2014.914907","article-title":"Publishing not perishing: how research students transition from novice to knowledgeable using systematic quantitative literature reviews","volume":"40","author":"Pickering","year":"2015","journal-title":"Stud. High. Educ."},{"key":"10.1016\/j.onehlt.2025.101081_bb0195","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/s41429-023-00601-6","article-title":"Persistence of resistance: a panel data analysis of the effect of antibiotic usage on the prevalence of resistance","volume":"76","author":"Rahman","year":"2023","journal-title":"J. Antibiot."},{"key":"10.1016\/j.onehlt.2025.101081_bb0200","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1111\/jep.12856","article-title":"Thinking about complexity in health: A systematic review of the key systems thinking and complexity ideas in health","volume":"24","author":"Rusoja","year":"2018","journal-title":"J. Eval. Clin. Pract."},{"key":"10.1016\/j.onehlt.2025.101081_bb0205","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.jgar.2021.08.001","article-title":"Environmental antimicrobial resistance and its drivers: a potential threat to public health","volume":"27","author":"Samreen Ahmad","year":"2021","journal-title":"J. Global Antimicrob. Resist."},{"key":"10.1016\/j.onehlt.2025.101081_bb0210","doi-asserted-by":"crossref","first-page":"113497","DOI":"10.1016\/j.ijheh.2020.113497","article-title":"What drives antibiotic use in the community? A systematic review of determinants in the human outpatient sector","volume":"226","author":"Schmiege","year":"2020","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0215","series-title":"The Fifth Discipline: The Art and Practice of the Learning Organization","author":"Senge","year":"1990"},{"key":"10.1016\/j.onehlt.2025.101081_bb0220","series-title":"Business Dynamics: Systems Thinking and moeling for a coplex world","author":"Sterman","year":"2000"},{"key":"10.1016\/j.onehlt.2025.101081_bb0225","doi-asserted-by":"crossref","DOI":"10.1007\/s11270-020-04526-w","article-title":"Using a system dynamics model for investigating potential levels of antibiotics pollution in the Volga River","volume":"231","author":"Sverdrup","year":"2020","journal-title":"Water Air Soil Pollut."},{"key":"10.1016\/j.onehlt.2025.101081_bb0230","doi-asserted-by":"crossref","DOI":"10.3390\/ijerph19116549","article-title":"A Rapid Review of Environmental Health Gaps in Antimicrobial Resistance and Water-Related Research from 1990\u20132020","volume":"19","author":"Taing","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0235","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2022-010191","article-title":"Development of the systems thinking for health actions framework: a literature review and a case study","volume":"8","author":"Thelen","year":"2023","journal-title":"BMJ Glob. Health"},{"key":"10.1016\/j.onehlt.2025.101081_bb0240","series-title":"WHO at UNGA: Call for Urgent, High-Level Action to Address Global Scourge of Antimicrobial Resistance","author":"WHO","year":"2024"},{"key":"10.1016\/j.onehlt.2025.101081_bb0245","series-title":"Systems Concepts in Action: A Practitioner's Toolkit","author":"Williams","year":"2020"},{"key":"10.1016\/j.onehlt.2025.101081_bb0250","doi-asserted-by":"crossref","first-page":"1553","DOI":"10.1038\/s41467-022-29283-8","article-title":"Assessment of global health risk of antibiotic resistance genes","volume":"13","author":"Zhang","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.onehlt.2025.101081_bb0255","doi-asserted-by":"crossref","first-page":"2490","DOI":"10.1080\/01605682.2020.1796537","article-title":"System dynamics modelling to formulate policy interventions to optimise antibiotic prescribing in hospitals","volume":"72","author":"Zhu","year":"2021","journal-title":"J. Oper. Res. Soc."}],"container-title":["One Health"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235277142500117X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S235277142500117X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:42:59Z","timestamp":1765413779000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S235277142500117X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":51,"alternative-id":["S235277142500117X"],"URL":"https:\/\/doi.org\/10.1016\/j.onehlt.2025.101081","relation":{},"ISSN":["2352-7714"],"issn-type":[{"value":"2352-7714","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Systems thinking to understand the complexity of antimicrobial resistance across One Health: A systematic review of current approaches","name":"articletitle","label":"Article Title"},{"value":"One Health","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.onehlt.2025.101081","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101081"}}