{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T09:00:20Z","timestamp":1762506020676},"reference-count":44,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T00:00:00Z","timestamp":1367366400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1016\/j.oooo.2012.09.002","type":"journal-article","created":{"date-parts":[[2012,12,12]],"date-time":"2012-12-12T12:47:11Z","timestamp":1355316431000},"page":"e66-e71","source":"Crossref","is-referenced-by-count":6,"title":["Metastatic Merkel cell carcinoma of the oral cavity in a human immunodeficiency virus\u2013positive patient and the detection of Merkel cell polyomavirus"],"prefix":"10.1016","volume":"115","author":[{"given":"Mengtao","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Negin","family":"Saghafi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Earl","family":"Freymiller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John R.","family":"Basile","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yi-Ling","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.oooo.2012.09.002_bib1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1097\/QCO.0b013e3283486d04","article-title":"Human herpesvirus 8\u2013associated neoplasms: the roles of viral replication and antiviral treatment","volume":"24","author":"Gantt","year":"2011","journal-title":"Curr Opin Infect Dis"},{"key":"10.1016\/j.oooo.2012.09.002_bib2","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.jcv.2011.12.021","article-title":"Assessment of immunovirological features in HIV related non-Hodgkin lymphoma patients and their impact on outcome","volume":"53","author":"Tedeschi","year":"2012","journal-title":"J Clin Virol"},{"key":"10.1016\/j.oooo.2012.09.002_bib3","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(02)07668-7","article-title":"Merkel cell carcinoma and HIV infection","volume":"359","author":"Engels","year":"2002","journal-title":"Lancet"},{"key":"10.1016\/j.oooo.2012.09.002_bib4","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1056\/NEJM199810223391715","article-title":"Merkel-cell carcinomas in patients treated with methoxsalen and ultraviolet A radiation","volume":"339","author":"Lunder","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1016\/j.oooo.2012.09.002_bib5","doi-asserted-by":"crossref","first-page":"5009","DOI":"10.1158\/0008-5472.CAN-08-0949","article-title":"Frequent detection of Merkel cell polyomavirus in human Merkel cell carcinomas and identification of a unique deletion in the VP1 gene","volume":"68","author":"Kassem","year":"2008","journal-title":"Cancer Res"},{"key":"10.1016\/j.oooo.2012.09.002_bib6","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/jid.2008.198","article-title":"MC polyomavirus is frequently present in Merkel cell carcinoma of European patients","volume":"129","author":"Becker","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.oooo.2012.09.002_bib7","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1126\/science.1152586","article-title":"Clonal integration of a polyomavirus in human Merkel cell carcinoma","volume":"319","author":"Feng","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.oooo.2012.09.002_bib8","doi-asserted-by":"crossref","first-page":"16272","DOI":"10.1073\/pnas.0806526105","article-title":"T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirus","volume":"105","author":"Shuda","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.oooo.2012.09.002_bib9","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1146\/annurev-pathol-011110-130227","article-title":"Merkel cell carcinoma: a virus-induced human cancer","volume":"7","author":"Chang","year":"2012","journal-title":"Annu Rev Pathol"},{"key":"10.1016\/j.oooo.2012.09.002_bib10","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1001\/archderm.1972.01620040075020","article-title":"Trabecular carcinoma of the skin","volume":"105","author":"Toker","year":"1972","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.oooo.2012.09.002_bib11","doi-asserted-by":"crossref","first-page":"2311","DOI":"10.1002\/1097-0142(197811)42:5<2311::AID-CNCR2820420531>3.0.CO;2-L","article-title":"Trabecular carcinoma of the skin: an ultrastructural study","volume":"42","author":"Tang","year":"1978","journal-title":"Cancer"},{"key":"10.1016\/j.oooo.2012.09.002_bib12","first-page":"427","article-title":"Cytokeratin 20 in human carcinomas","volume":"140","author":"Moll","year":"1992","journal-title":"Am J Pathol"},{"key":"10.1016\/j.oooo.2012.09.002_bib13","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.5858\/2009-0165-RSR2.1","article-title":"Merkel cell carcinoma","volume":"134","author":"Wong","year":"2010","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.oooo.2012.09.002_bib14","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1097\/00000478-198502000-00005","article-title":"Primary neuroendocrine (Merkel cell?) carcinoma of the skin","volume":"9","author":"Sibley","year":"1985","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.oooo.2012.09.002_bib15","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/00000478-198502000-00004","article-title":"Primary neuroendocrine (Merkel cell?) carcinoma of the skin","volume":"9","author":"Sibley","year":"1985","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.oooo.2012.09.002_bib16","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1083\/jcb.200907080","article-title":"Epidermal progenitors give rise to Merkel cells during embryonic development and adult homeostasis","volume":"187","author":"Van Keymeulen","year":"2009","journal-title":"J Cell Biol"},{"key":"10.1016\/j.oooo.2012.09.002_bib17","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/S0190-9622(03)02108-X","article-title":"Epidemiology of primary Merkel cell carcinoma in the United States","volume":"49","author":"Agelli","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.oooo.2012.09.002_bib18","doi-asserted-by":"crossref","first-page":"274","DOI":"10.3109\/2000656X.2011.613233","article-title":"2011","volume":"45","author":"Lyhne","year":"2011","journal-title":"J Plast Surg Hand Surg"},{"key":"10.1016\/j.oooo.2012.09.002_bib19","series-title":"Cancer Epidemiol","article-title":"Increased incidence of Merkel cell carcinoma among younger statin users","author":"Sahi","year":"2012"},{"key":"10.1016\/j.oooo.2012.09.002_bib20","doi-asserted-by":"crossref","first-page":"354","DOI":"10.2340\/00015555-1038","article-title":"Rapid growth of Merkel cell carcinoma during etanercept treatment of psoriatic arthritis: cause or coincidence?","volume":"91","author":"de Giorgi","year":"2011","journal-title":"Acta Derm Venereol"},{"key":"10.1016\/j.oooo.2012.09.002_bib21","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1111\/j.1365-2230.2005.01800.x","article-title":"Merkel cell carcinoma in a patient with chronic sarcoidosis","volume":"30","author":"McLoone","year":"2005","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.oooo.2012.09.002_bib22","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/j.1365-2133.1997.tb03802.x","article-title":"Merkel cell carcinoma arising after therapeutic immunosuppression","volume":"137","author":"Gooptu","year":"1997","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.oooo.2012.09.002_bib23","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1365-2141.2012.09087.x","article-title":"Increased incidence of chronic lymphocytic leukaemia and lymphomas in patients with Merkel cell carcinoma\u2014a population based study of 335 cases with neuroendocrine skin tumour","volume":"157","author":"Tadmor","year":"2012","journal-title":"Br J Haematol"},{"key":"10.1016\/j.oooo.2012.09.002_bib24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.jss.2012.03.067","article-title":"Merkel cell carcinoma: high recurrence rate despite aggressive treatment","volume":"177","author":"Soult","year":"2012","journal-title":"J Surg Res"},{"key":"10.1016\/j.oooo.2012.09.002_bib25","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.bjoms.2009.06.008","article-title":"Spontaneous regression of advanced Merkel-cell\u2013like small cell carcinoma of the parotid gland","volume":"48","author":"Mulder","year":"2010","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.oooo.2012.09.002_bib26","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1159\/000327000","article-title":"Sustained remission of a primary nodal Merkel cell carcinoma in an HIV-positive patient","volume":"34","author":"Brugnaro","year":"2011","journal-title":"Onkologie"},{"key":"10.1016\/j.oooo.2012.09.002_bib27","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1258\/jrsm.96.5.238","article-title":"Sustained remission of metastatic Merkel cell carcinoma with treatment of HIV infection","volume":"96","author":"Burack","year":"2003","journal-title":"J R Soc Med"},{"key":"10.1016\/j.oooo.2012.09.002_bib28","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.jaad.2007.11.020","article-title":"Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features","volume":"58","author":"Heath","year":"2008","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.oooo.2012.09.002_bib29","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1111\/j.1600-0560.2009.01370.x","article-title":"Merkel cell carcinoma demographics, morphology, and survival based on 3870 cases: a population based study","volume":"37","author":"Albores-Saavedra","year":"2010","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.oooo.2012.09.002_bib30","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/QAD.0b013e328340a19c","article-title":"Merkel cell carcinoma associated with HIV: review of 14 patients","volume":"25","author":"Izikson","year":"2011","journal-title":"AIDS"},{"key":"10.1016\/j.oooo.2012.09.002_bib31","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1177\/002215540205000802","article-title":"DNA extraction from archival formalin-fixed, paraffin-embedded tissue sections based on the antigen retrieval principle: heating under the influence of pH","volume":"50","author":"Shi","year":"2002","journal-title":"J Histochem Cytochem"},{"key":"10.1016\/j.oooo.2012.09.002_bib32","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.1002\/ijc.24737","article-title":"Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission","volume":"126","author":"Loyo","year":"2010","journal-title":"Int J Cancer"},{"key":"10.1016\/j.oooo.2012.09.002_bib33","doi-asserted-by":"crossref","first-page":"7099","DOI":"10.1182\/blood-2010-09-310557","article-title":"Merkel cell polyomavirus DNA sequences in the buffy coats of healthy blood donors","volume":"117","author":"Pancaldi","year":"2011","journal-title":"Blood"},{"key":"10.1016\/j.oooo.2012.09.002_bib34","doi-asserted-by":"crossref","first-page":"685","DOI":"10.3201\/eid1604.091278","article-title":"Merkel cell polyomavirus in cutaneous swabs","volume":"16","author":"Foulongne","year":"2010","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.oooo.2012.09.002_bib35","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1128\/CVI.05175-11","article-title":"Age-specific seroprevalence of Merkel cell polyomavirus, BK virus, and JC virus","volume":"18","author":"Viscidi","year":"2011","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.oooo.2012.09.002_bib36","doi-asserted-by":"crossref","first-page":"e1000578","DOI":"10.1371\/journal.ppat.1000578","article-title":"Quantitation of human seroresponsiveness to Merkel cell polyomavirus","volume":"5","author":"Pastrana","year":"2009","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.oooo.2012.09.002_bib37","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1002\/ijc.24509","article-title":"Human Merkel cell polyomavirus infection II","volume":"125","author":"Tolstov","year":"2009","journal-title":"Int J Cancer"},{"key":"10.1016\/j.oooo.2012.09.002_bib38","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1001\/archdermatol.2011.42","article-title":"Merkel cell polyomavirus infection in HIV-positive men","volume":"147","author":"Wieland","year":"2011","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.oooo.2012.09.002_bib39","doi-asserted-by":"crossref","first-page":"7064","DOI":"10.1128\/JVI.02400-09","article-title":"Merkel cell polyomavirus-infected Merkel cell carcinoma cells require expression of viral T antigens","volume":"84","author":"Houben","year":"2010","journal-title":"J Virol"},{"key":"10.1016\/j.oooo.2012.09.002_bib40","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1038\/296671a0","article-title":"Enhanced transformation of human fibroblasts by origin-defective simian virus 40","volume":"296","author":"Small","year":"1982","journal-title":"Nature"},{"key":"10.1016\/j.oooo.2012.09.002_bib41","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.tripleo.2010.04.007","article-title":"Oral cavity neuroendocrine carcinoma: a comparison study with cutaneous Merkel cell carcinoma and other mucosal head and neck neuroendocrine carcinomas","volume":"110","author":"Lewis","year":"2010","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2012.09.002_bib42","author":"Washington"},{"key":"10.1016\/j.oooo.2012.09.002_bib43","doi-asserted-by":"crossref","first-page":"2717","DOI":"10.1056\/NEJMcpc0803063","article-title":"Case records of the Massachusetts General Hospital. Case 19 2008. A 63-year-old HIV-positive man with cutaneous Merkel-cell carcinoma","author":"Busse","year":"2008","journal-title":"N Engl J Med"},{"key":"10.1016\/j.oooo.2012.09.002_bib44","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/1097-0339(200103)24:3<186::AID-DC1038>3.0.CO;2-W","article-title":"Fine-needle aspiration diagnosis of unusual cutaneous neoplasms of the scalp in HIV-infected patients: a report of two cases and review of the literature","volume":"24","author":"Solomon","year":"2001","journal-title":"Diagn Cytopathol"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440312015106?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440312015106?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,5,3]],"date-time":"2024-05-03T05:23:30Z","timestamp":1714713810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212440312015106"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":44,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013,5]]}},"alternative-id":["S2212440312015106"],"URL":"https:\/\/doi.org\/10.1016\/j.oooo.2012.09.002","relation":{},"ISSN":["2212-4403"],"issn-type":[{"value":"2212-4403","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}