{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T15:28:02Z","timestamp":1758814082808},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2013,8,1]],"date-time":"2013-08-01T00:00:00Z","timestamp":1375315200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T00:00:00Z","timestamp":1404864000000},"content-version":"vor","delay-in-days":342,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"published-print":{"date-parts":[[2013,8]]},"DOI":"10.1016\/j.oooo.2013.05.007","type":"journal-article","created":{"date-parts":[[2013,7,9]],"date-time":"2013-07-09T15:34:58Z","timestamp":1373384098000},"page":"210-213","source":"Crossref","is-referenced-by-count":4,"title":["WWOX expression in giant cell lesions of the jaws"],"prefix":"10.1016","volume":"116","author":[{"given":"Fabr\u00edcio Rezende","family":"Amaral","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina Gon\u00e7alves","family":"Diniz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa F\u00e1tima","family":"Bernardes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo Eduardo Alencar","family":"Souza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo Santiago","family":"Gomez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina Cavali\u00e9ri","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.oooo.2013.05.007_bib1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/j.tripleo.2007.04.003","article-title":"Central giant cell granuloma of the jaw: a review of the literature with emphasis on therapy options","volume":"104","author":"de Lange","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2013.05.007_bib2","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/S0009-9260(89)80325-3","article-title":"Central giant cell granuloma of the jaws. A clinico-radiological study","volume":"40","author":"Horner","year":"1989","journal-title":"Clin Radiol"},{"key":"10.1016\/j.oooo.2013.05.007_bib3","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/S0901-5027(88)80158-9","article-title":"Peripheral giant cell granuloma. Clinicopathologic study of 224 new cases and review of 956 reported cases","volume":"17","author":"Katsikeris","year":"1998","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.oooo.2013.05.007_bib4","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1034\/j.1600-0714.2003.00069.x","article-title":"Cellular mechanisms of osteoclast formation and lacunar in giant cell granuloma of the jaw","volume":"32","author":"Itonaga","year":"2003","journal-title":"J\u00a0Oral Pathol Med"},{"key":"10.1016\/j.oooo.2013.05.007_bib5","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1601-0825.2000.tb00319.x","article-title":"Evaluation of p53, PCNA, Ki-67, MDM2 and AgNOR in oral peripheral and central giant cell lesions","volume":"6","author":"Souza","year":"2000","journal-title":"Oral Dis"},{"key":"10.1016\/j.oooo.2013.05.007_bib6","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/0964-1955(95)00037-2","article-title":"PCNA and p53","volume":"31B","author":"Mighell","year":"1995","journal-title":"Eur J Cancer B Oral Oncol"},{"key":"10.1016\/j.oooo.2013.05.007_bib7","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/j.1600-0714.1997.tb00451.x","article-title":"Central giant cell granulomas of the jaws: phenotype and proliferation-associated markers","volume":"26","author":"O'Malley","year":"1997","journal-title":"J\u00a0Oral Pathol Med"},{"key":"10.1016\/j.oooo.2013.05.007_bib8","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/88832","article-title":"Mutations in the gene encoding c-Abl-binding protein SH3BP2 cause cherubism","volume":"28","author":"Ueki","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.oooo.2013.05.007_bib9","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/0030-4220(92)90137-F","article-title":"Cherubism: diagnosis, treatment, and comparison with central giant cell granulomas and giant cell tumors","volume":"73","author":"Kaugars","year":"1992","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"10.1016\/j.oooo.2013.05.007_bib10","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jcms.2004.07.006","article-title":"Cherubism \u2013 new hypotheses on pathogenesis and therapeutic consequences","volume":"33","author":"Hyckel","year":"2005","journal-title":"J\u00a0Craniomaxillofac Surg"},{"key":"10.1016\/j.oooo.2013.05.007_bib11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1086\/302454","article-title":"The gene for cherubism maps to chromosome 4p16.3","volume":"65","author":"Mangion","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.oooo.2013.05.007_bib12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.cell.2006.12.019","article-title":"Jawing about TNF: new hope for cherubism","volume":"128","author":"Novack","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.oooo.2013.05.007_bib13","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1196\/annals.1402.071","article-title":"The role of NFAT in osteoclast formation","volume":"1116","author":"Takayanagi","year":"2007","journal-title":"Ann N\u00a0Y Acad Sci"},{"key":"10.1016\/j.oooo.2013.05.007_bib14","first-page":"2140","article-title":"WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23. 3-24. 1, a region frequently affected in breast cancer","volume":"60","author":"Bednarek","year":"2000","journal-title":"Cancer Res"},{"key":"10.1016\/j.oooo.2013.05.007_bib15","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1093\/hmg\/9.11.1651","article-title":"Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation\u00a0breakpoints in cancer cells","volume":"9","author":"Ried","year":"2000","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.oooo.2013.05.007_bib16","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1159\/000072844","article-title":"WWOX, the common chromosomal fragile site, FRA16D, cancer gene","volume":"100","author":"Ludes-Meyers","year":"2003","journal-title":"Cytogenet Genome Res"},{"key":"10.1016\/j.oooo.2013.05.007_bib17","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.canlet.2005.07.041","article-title":"Common chromosomal fragile site and cancer. Focus on FRA16D","volume":"232","author":"O'Keefe","year":"2006","journal-title":"Cancer Lett"},{"key":"10.1016\/j.oooo.2013.05.007_bib18","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1111\/j.1601-0825.2011.01802.x","article-title":"Impact of WWOX alterations on p73, DNp73, p53, cell proliferation and DNA ploidy in salivary gland neoplasms","volume":"17","author":"Gomes","year":"2011","journal-title":"Oral Dis"},{"key":"10.1016\/j.oooo.2013.05.007_bib19","doi-asserted-by":"crossref","first-page":"11417","DOI":"10.1073\/pnas.191175898","article-title":"WWOX: a candidate tumour suppressor gene involved in multiple tumour types","volume":"98","author":"Paige","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.oooo.2013.05.007_bib20","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1002\/ijc.21446","article-title":"Characterization of the tumour suppressor gene WWOX in primary human oral squamous cell carcinomas","volume":"118","author":"Pimenta","year":"2006","journal-title":"Int J Cancer"},{"key":"10.1016\/j.oooo.2013.05.007_bib21","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.oraloncology.2007.08.019","article-title":"Molecular alterations in the tumour suppressor gene WWOX in oral leukoplakias","volume":"44","author":"Pimenta","year":"2008","journal-title":"Oral Oncol"},{"key":"10.1016\/j.oooo.2013.05.007_bib22","doi-asserted-by":"crossref","first-page":"4401","DOI":"10.1073\/pnas.0400805101","article-title":"Functional association between Wwox tumour suppressor protein and p73, a p53 homolog","volume":"101","author":"Aqeilan","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.oooo.2013.05.007_bib23","first-page":"877","article-title":"WWOX tumor suppressor gene","volume":"23","author":"Yang","year":"2008","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.oooo.2013.05.007_bib24","doi-asserted-by":"crossref","first-page":"15611","DOI":"10.1073\/pnas.0505485102","article-title":"WWOX gene restoration prevents lung cancer growth in vitro and in vivo","volume":"102","author":"Fabbri","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.oooo.2013.05.007_bib25","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1158\/1078-0432.CCR-06-2038","article-title":"Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression","volume":"13","author":"Iliopoulos","year":"2007","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.oooo.2013.05.007_bib26","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1007\/s13277-011-0201-6","article-title":"Quantitative expression analysis of apoptotic\/antiapoptotic genes and association with immunolocalization of BAX and BCL-2 in peripheral and central giant cell lesions of the jaws","volume":"32","author":"Amaral","year":"2011","journal-title":"Tumour Biol"},{"key":"10.1016\/j.oooo.2013.05.007_bib27","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/0278-2391(86)90040-6","article-title":"Central giant cell lesions of the jaws: a clinicopathologic study","volume":"44","author":"Chuong","year":"1986","journal-title":"J\u00a0Oral Maxillofac Surg"},{"key":"10.1016\/j.oooo.2013.05.007_bib28","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.oraloncology.2007.01.012","article-title":"A\u00a0novel mutation of the SH3BP2 gene in an aggressive case of cherubism","volume":"44","author":"Carvalho","year":"2008","journal-title":"Oral Oncol"},{"key":"10.1016\/j.oooo.2013.05.007_bib29","doi-asserted-by":"crossref","first-page":"5577","DOI":"10.1158\/0008-5472.CAN-09-4602","article-title":"Frequent attenuation of the WWOX tumor suppressor in osteosarcoma is associated with increased tumorigenicity and aberrant RUNX2 expression","volume":"70","author":"Kurek","year":"2010","journal-title":"Cancer Res"},{"key":"10.1016\/j.oooo.2013.05.007_bib30","first-page":"499","article-title":"Evidence of molecular alterations in the tumour suppressor gene WWOX in benign and malignant bone related lesions of the jaws","volume":"25","author":"Diniz","year":"2011","journal-title":"Oncol Rep"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440313002356?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440313002356?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,14]],"date-time":"2018-10-14T18:21:43Z","timestamp":1539541303000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212440313002356"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,8]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,8]]}},"alternative-id":["S2212440313002356"],"URL":"https:\/\/doi.org\/10.1016\/j.oooo.2013.05.007","relation":{},"ISSN":["2212-4403"],"issn-type":[{"value":"2212-4403","type":"print"}],"subject":[],"published":{"date-parts":[[2013,8]]}}}