{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T22:05:54Z","timestamp":1759961154797},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,3,10]],"date-time":"2017-03-10T00:00:00Z","timestamp":1489104000000},"content-version":"vor","delay-in-days":343,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","oooojournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.oooo.2015.12.002","type":"journal-article","created":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T10:07:13Z","timestamp":1450519633000},"page":"412-418","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Human papillomavirus in tonsillar squamous cell carcinomas from Guatemala and Brazil"],"prefix":"10.1016","volume":"121","author":[{"given":"Alicia Rumayor","family":"Pi\u00f1a","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"La\u00edsa Simakawa","family":"Jimenez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernanda Viviane","family":"Mariano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno Augusto Benevenuto","family":"de Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rom\u00e1n","family":"Carlos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Albina","family":"Altemani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oslei Paes","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.oooo.2015.12.002_bib1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.anndiagpath.2011.07.003","article-title":"Changing trends in human papillomavirus\u2013associated head and neck squamous cell carcinoma","volume":"16","author":"Wang","year":"2012","journal-title":"Ann Diagn Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib2","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.oraloncology.2013.12.019","article-title":"Epidemiology of HPV-associated oropharyngeal cancer","volume":"50","author":"Pytynia","year":"2014","journal-title":"Oral Oncol"},{"key":"10.1016\/j.oooo.2015.12.002_bib3","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1007\/s10552-014-0348-8","article-title":"Human papillomavirus (HPV) 16 and the prognosis of head and neck cancer in a geographical region with a low prevalence of HPV infection","volume":"25","author":"L\u00f3pez","year":"2014","journal-title":"Cancer Causes Control"},{"key":"10.1016\/j.oooo.2015.12.002_bib4","series-title":"ICO Information Centre on HPV and Cancer (HPV Information Centre). Human Papillomavirus and Related Diseases in Guatemala. Summary Report","author":"Bruni","year":"2015"},{"key":"10.1016\/j.oooo.2015.12.002_bib5","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/S1808-8694(15)30753-9","article-title":"Epidemiologic evaluation of head and neck patients in a university hospital of Northwestern S\u00e3o Paulo State","volume":"74","author":"Alvarenga Lde","year":"2008","journal-title":"Braz J Otorhinolaryngol"},{"key":"10.1016\/j.oooo.2015.12.002_bib6","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/S0002-9610(98)00246-3","article-title":"Low prevalence of human papillomavirus in a geographic region with a high incidence of head and neck cancer","volume":"176","author":"Miguel","year":"1998","journal-title":"Am J Surg"},{"key":"10.1016\/j.oooo.2015.12.002_bib7","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1590\/S1516-18462009000700020","article-title":"Characterizing the population with mouth and oropharyngeal cancer, attended in the sector of head and neck in a referral hospital in Salvador City \u2013 BA","volume":"11","author":"Silva","year":"2009","journal-title":"Rev CEFAC [online]"},{"key":"10.1016\/j.oooo.2015.12.002_bib8","first-page":"351","article-title":"Epidemiological profile of incident cases of oral and pharyngeal cancer","volume":"58","author":"Melo","year":"2010","journal-title":"Rev Ga\u00facha Odontol"},{"key":"10.1016\/j.oooo.2015.12.002_bib9","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.oraloncology.2011.12.013","article-title":"International incidence of oropharyngeal cancer: a population-based study","volume":"48","author":"de Camargo Cancela","year":"2012","journal-title":"Oral Oncol"},{"key":"10.1016\/j.oooo.2015.12.002_bib10","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1097\/PAS.0b013e3181e84652","article-title":"p16 Positive oropharyngeal squamous cell carcinoma: an entity with a favorable prognosis regardless of tumor HPV status","volume":"34","author":"Lewis","year":"2010","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib11","doi-asserted-by":"crossref","first-page":"S16","DOI":"10.1007\/s12105-012-0377-0","article-title":"Epidemiology and clinical aspects of HPV in head and neck cancers","volume":"6","author":"Chaturvedi","year":"2012","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib12","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1016\/S0002-9440(10)63576-6","article-title":"Absence of human papillomavirus in tonsillar squamous cell carcinomas from Chinese patients","volume":"163","author":"Li","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib13","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1016\/S1470-2045(10)70017-6","article-title":"HPV-associated head and neck cancer: a virus-related cancer epidemic","volume":"11","author":"Marur","year":"2010","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.oooo.2015.12.002_bib14","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/S1470-2045(14)70471-1","article-title":"HPV DNA, E6\/E7 mRNA, and p16 INK4a detection in head and neck cancers: a systematic review and meta-analysis","volume":"15","author":"Ndiaye","year":"2014","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.oooo.2015.12.002_bib15","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1158\/1055-9965.EPI-04-0551","article-title":"Human papillomavirus types in head and neck squamous cell carcinomas worldwide: a systematic review","volume":"14","author":"Kreimer","year":"2005","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.oooo.2015.12.002_bib16","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1097\/00000478-200311000-00010","article-title":"Prevalence of human papillomavirus type 16 DNA in squamous cell carcinoma of the palatine tonsil, and not the oral cavity, in young patients. A distinct clinicopathologic and molecular disease entity","volume":"27","author":"El Mofty","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib17","first-page":"001","article-title":"Worldwide prevalence of human papillomavirus in tonsillar squamous cell carcinoma and tumor-free tonsillar tissue","volume":"S2","author":"Rusan","year":"2012","journal-title":"Otolaryngology"},{"key":"10.1016\/j.oooo.2015.12.002_bib18","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.oooo.2012.05.003","article-title":"Frequency and genotype distribution of multiple human papillomavirus infections in cancer of the head and neck in a Mexican population","volume":"114","author":"Ibieta-Zarco","year":"2012","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.oooo.2015.12.002_bib19","first-page":"371570","article-title":"Absence of HPV infection is associated with smoker patients with squamous cell carcinoma of the oropharynx","volume":"2014","author":"Soares","year":"2014","journal-title":"J\u00a0Oncol"},{"key":"10.1016\/j.oooo.2015.12.002_bib20","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.oraloncology.2008.07.008","article-title":"Oropharyngeal carcinoma in non-smokers and non-drinkers: a role for HPV","volume":"45","author":"Andrews","year":"2009","journal-title":"Oral Oncol"},{"key":"10.1016\/j.oooo.2015.12.002_bib21","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1093\/ije\/dyq249","article-title":"Low human papillomavirus prevalence in head and neck cancer: results from two large case-control studies in high-incidence regions","volume":"40","author":"Ribeiro","year":"2011","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.oooo.2015.12.002_bib22","first-page":"6469","article-title":"Detection of human papillomavirus in cervical lymph nodes: a highly effective strategy for localizing site of tumor origin","volume":"9","author":"Begum","year":"2003","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.oooo.2015.12.002_bib23","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1590\/S0104-42302004000300029","article-title":"Human papillomavirus (HPV) infection and its relation with squamous cell carcinoma of the mouth and oropharynx","volume":"50","author":"Tinoco","year":"2004","journal-title":"Rev Assoc Med Bras"},{"key":"10.1016\/j.oooo.2015.12.002_bib24","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1097\/COC.0b013e31826b9920","article-title":"Five-year outcomes of squamous cell carcinoma of the tonsil treated with radiotherapy","volume":"37","author":"Mourad","year":"2014","journal-title":"Am J Clin Oncol"},{"key":"10.1016\/j.oooo.2015.12.002_bib25","doi-asserted-by":"crossref","first-page":"S41","DOI":"10.1007\/s12105-012-0373-4","article-title":"Morphologic features of conventional squamous cell carcinoma of the oropharynx: \u201ckeratinizing\u201d and \u201cnonkeratinizing\u201d histologic types as the basis for a consistent classification system","volume":"6","author":"Chernock","year":"2012","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib26","doi-asserted-by":"crossref","first-page":"5694","DOI":"10.1158\/1078-0432.CCR-05-0587","article-title":"Tissue distribution of human papillomavirus 16 DNA integration in patients with tonsillar carcinoma","volume":"11","author":"Begum","year":"2005","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.oooo.2015.12.002_bib27","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1007\/s12105-009-0100-y","article-title":"The changing face of head and neck cancer in the 21st century: the impact of HPV on the epidemiology and pathology of oral cancer","volume":"3","author":"Westra","year":"2009","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib28","doi-asserted-by":"crossref","first-page":"S48","DOI":"10.1007\/s12105-012-0371-6","article-title":"The morphologic profile of HPV-related head and neck squamous carcinoma: implications for diagnosis, prognosis, and clinical management","volume":"6","author":"Westra","year":"2012","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib29","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1365-2559.2011.04092.x","article-title":"Recognition of nonkeratinizing morphology in oropharyngeal squamous cell carcinoma\u2014a prospective cohort and interobserver variability study","volume":"60","author":"Lewis","year":"2012","journal-title":"Histopathology"},{"key":"10.1016\/j.oooo.2015.12.002_bib30","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.humpath.2011.05.010","article-title":"The relationship between p16 expression and high-risk human papillomavirus infection in squamous cell carcinomas from sites other than uterine cervix: a study of 137 cases","volume":"43","author":"Doxtader","year":"2012","journal-title":"Hum Pathol"},{"key":"10.1016\/j.oooo.2015.12.002_bib31","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.clon.2013.07.003","article-title":"The prognostic significance of the biomarker p16 in oropharyngeal squamous cell carcinoma","volume":"25","author":"Oguejiofor","year":"2013","journal-title":"Clin Oncol (R Coll Radiol)"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440315013383?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440315013383?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,22]],"date-time":"2019-08-22T07:04:11Z","timestamp":1566457451000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212440315013383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S2212440315013383"],"URL":"https:\/\/doi.org\/10.1016\/j.oooo.2015.12.002","relation":{},"ISSN":["2212-4403"],"issn-type":[{"value":"2212-4403","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human papillomavirus in tonsillar squamous cell carcinomas from Guatemala and Brazil","name":"articletitle","label":"Article Title"},{"value":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.oooo.2015.12.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}