{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:41:50Z","timestamp":1788309710757,"version":"build-2803163510"},"reference-count":67,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2018,3,1]],"date-time":"2018-03-01T00:00:00Z","timestamp":1519862400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","oooojournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"published-print":{"date-parts":[[2018,3]]},"DOI":"10.1016\/j.oooo.2017.10.006","type":"journal-article","created":{"date-parts":[[2017,11,4]],"date-time":"2017-11-04T00:05:47Z","timestamp":1509753947000},"page":"e54-e66","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Drug-associated hyperpigmentation of the oral mucosa: report of four cases"],"prefix":"10.1016","volume":"125","author":[{"given":"Konstantinos I.","family":"Tosios","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleni-Marina","family":"Kalogirou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandra","family":"Sklavounou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.oooo.2017.10.006_bib0010","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/154411130401500405","article-title":"Adverse drug reactions in the orofacial region","volume":"15","author":"Scully","year":"2004","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.oooo.2017.10.006_bib0015","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/j.1600-0560.1987.tb00493.x","article-title":"Minocycline-related cutaneous hyperpigmentation as demonstrated by light microscopy, electron microscopy and X-ray energy spectroscopy","volume":"14","author":"Argenyi","year":"1987","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0020","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1007\/s12105-011-0325-4","article-title":"Mucosal pigmentation caused by imatinib: report of three cases","volume":"6","author":"Li","year":"2012","journal-title":"Head Neck Pathol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0025","doi-asserted-by":"crossref","first-page":"4","DOI":"10.5070\/D3498194BX","article-title":"Oral melanosis after tyrosine kinase inhibition with Imatinib for chronic myelogenous leukemia: report of a case and review of the literature","volume":"17","author":"Wong","year":"2011","journal-title":"Dermatol Online J"},{"key":"10.1016\/j.oooo.2017.10.006_bib0030","first-page":"644","article-title":"Drug-induced hyperpigmentation: a systematic review","volume":"11","author":"Krause","year":"2013","journal-title":"J Dtsch Dermatol Ges"},{"key":"10.1016\/j.oooo.2017.10.006_bib0035","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1001\/jamadermatol.2013.709","article-title":"Hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematosus: a case-control study","volume":"149","author":"Jallouli","year":"2013","journal-title":"JAMA Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0040","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1016\/j.tripleo.2003.11.006","article-title":"Oral mucosal pigmentation secondary to minocycline therapy: report of two cases and a review of the literature","volume":"97","author":"Treister","year":"2004","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0045","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1016\/j.tripleo.2010.11.006","article-title":"Oral pigmentation in the hard palate associated with imatinib mesylate therapy: a report of three cases","volume":"111","author":"Mattsson","year":"2011","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0050","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1111\/j.1365-2230.2011.04196.x","article-title":"Oral mucosal hyperpigmentation and horizontal melanonychia caused by imatinib","volume":"37","author":"Steele","year":"2012","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0055","doi-asserted-by":"crossref","first-page":"e115","DOI":"10.1016\/j.bjoms.2014.07.220","article-title":"Palatal hyperpigmentation in a patient with chronic myeloid leukaemia on imatinib mesylate therapy","volume":"52","author":"Hindocha","year":"2014","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.oooo.2017.10.006_bib0060","first-page":"79","article-title":"Rare oral manifestation of chronic myelogenous leukemia and its targeted therapy: a case report and literature review","volume":"1","author":"Loudon","year":"2012","journal-title":"Univ J Med Dent"},{"key":"10.1016\/j.oooo.2017.10.006_bib0065","first-page":"817094","article-title":"A rare case of melanosis of the hard palate mucosa in a patient with chronic myeloid leukemia","volume":"2015","author":"Romeo","year":"2015","journal-title":"Case Rep Dent"},{"key":"10.1016\/j.oooo.2017.10.006_bib0070","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1600-051X.2005.00646.x","article-title":"Minocycline-associated intra-oral soft-tissue pigmentation: clinicopathologic correlations and review","volume":"32","author":"LaPorta","year":"2005","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0075","doi-asserted-by":"crossref","first-page":"e140","DOI":"10.1016\/j.jcms.2011.07.010","article-title":"Imatinib-associated hyperpigmentation of the palate in post-HSCT patient","volume":"40","author":"Resende","year":"2012","journal-title":"J Craniomaxillofac Surg"},{"key":"10.1016\/j.oooo.2017.10.006_bib0080","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1067\/moe.2000.106340","article-title":"Oral mucosal hyperpigmentation secondary to antimalarial drug therapy","volume":"90","author":"Kleinegger","year":"2000","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0085","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.tripleo.2007.07.047","article-title":"Pigmented lesions of the oral mucosa and perioral tissues: a flow-chart for the diagnosis and some recommendations for the management","volume":"105","author":"Meleti","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0090","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.oooo.2014.11.015","article-title":"Pigmented lesions on the mucosa: a wide range of diagnoses","volume":"119","author":"Fernandes","year":"2015","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0095","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1007\/s00520-008-0536-8","article-title":"Skin and oral lesions associated to imatinib mesylate therapy","volume":"17","author":"Basso","year":"2009","journal-title":"Support Care Cancer"},{"key":"10.1016\/j.oooo.2017.10.006_bib0100","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.amjmed.2006.07.031","article-title":"The tarnished tongue","volume":"119","author":"Alkhatib","year":"2006","journal-title":"Am J Med"},{"key":"10.1016\/j.oooo.2017.10.006_bib0105","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.clinthera.2005.09.005","article-title":"Safety of doxycycline and minocycline: a systematic review","volume":"27","author":"Smith","year":"2005","journal-title":"Clin Ther"},{"key":"10.1016\/j.oooo.2017.10.006_bib0110","first-page":"205","article-title":"Minocycline-induced hyperpigmentation of the tongue: successful treatment with the Q-switched ruby laser","volume":"28","author":"Friedman","year":"2002","journal-title":"Dermatol Surg"},{"key":"10.1016\/j.oooo.2017.10.006_bib0115","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1111\/j.1365-2133.1996.tb06972.x","article-title":"Safety of long-term high-dose minocycline in the treatment of acne","volume":"134","author":"Goulden","year":"1996","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0120","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1365-2230.2004.01421.x","article-title":"A new type of minocycline-induced cutaneous hyperpigmentation","volume":"29","author":"Mouton","year":"2004","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0125","doi-asserted-by":"crossref","first-page":"836","DOI":"10.1016\/j.jaad.2007.04.028","article-title":"The histopathology of subcutaneous minocycline pigmentation","volume":"57","author":"Bowen","year":"2007","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0130","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S1079-2104(05)80128-3","article-title":"Oral presentation of minocycline-induced black bone disease","volume":"79","author":"Odell","year":"1995","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0135","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/S1079-2104(05)80279-3","article-title":"Lingual hyperpigmentation associated with minocycline therapy","volume":"79","author":"Meyerson","year":"1995","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0140","first-page":"46","article-title":"Minocycline-induced hyperpigmentation involving the oral mucosa after short-term minocycline use","volume":"92","author":"Filitis","year":"2013","journal-title":"Cutis"},{"key":"10.1016\/j.oooo.2017.10.006_bib0145","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0140-6736(97)80019-0","article-title":"Minocycline-induced oral hyperpigmentation","volume":"349","author":"Eisen","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.oooo.2017.10.006_bib0150","first-page":"58","article-title":"Bluish-grey pigmentation of fingernails, gingiva, teeth and peri-oral region. Minocycline","volume":"62","author":"Herbers","year":"2004","journal-title":"Neth J Med"},{"key":"10.1016\/j.oooo.2017.10.006_bib0155","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1093\/annonc\/mdh068","article-title":"Pigmentary changes in chronic myeloid leukemia patients treated with imatinib mesylate","volume":"15","author":"Arora","year":"2004","journal-title":"Ann Oncol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0160","doi-asserted-by":"crossref","first-page":"7","DOI":"10.5070\/D3472203P2","article-title":"Persistent cutaneous hyperpigmentation after tyrosine kinase inhibition with imatinib for GIST","volume":"14","author":"Alexandrescu","year":"2008","journal-title":"Dermatol Online J"},{"key":"10.1016\/j.oooo.2017.10.006_bib0165","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1111\/ced.12261","article-title":"Inhibitory effects of imatinib mesylate on human epidermal melanocytes","volume":"39","author":"Wang","year":"2014","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0170","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/ors.12194","article-title":"Intraoral hyperpigmentation due to imatinib mesylate. A review of the literature","volume":"9","author":"Pancholi","year":"2016","journal-title":"Oral Surg"},{"key":"10.1016\/j.oooo.2017.10.006_bib0175","first-page":"24","article-title":"Diffuse pigmentation of the palate","volume":"100","author":"Lewis","year":"2009","journal-title":"J Okla Dent Assoc"},{"key":"10.1016\/j.oooo.2017.10.006_bib0180","first-page":"764","article-title":"Oral and maxillofacial pathology case of the month. Palatal melanosis associated with imatinib mesylate therapy","volume":"129","author":"Yu","year":"2012","journal-title":"Tex Dent J"},{"key":"10.1016\/j.oooo.2017.10.006_bib0185","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/ajh.23589","article-title":"Imatinib-associated melanosis of the palate","volume":"89","author":"Roeker","year":"2014","journal-title":"Am J Hematol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0190","doi-asserted-by":"crossref","first-page":"186","DOI":"10.3109\/10428194.2012.702904","article-title":"Hyperpigmentation of the hard palate associated with imatinib therapy for chronic myeloid leukemia with a genetic variation in the proto-oncogene c-KIT","volume":"54","author":"Khoo","year":"2013","journal-title":"Leuk Lymphoma"},{"key":"10.1016\/j.oooo.2017.10.006_bib0195","doi-asserted-by":"crossref","first-page":"532","DOI":"10.5021\/ad.2014.26.4.532","article-title":"Imatinib mesylate-induced hyperpigmentation of the nose and palate","volume":"26","author":"Song","year":"2014","journal-title":"Ann Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0200","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2015-209335","article-title":"Mucosal pigmentation of the hard palate in a patient taking imatinib","author":"Lyne","year":"2015","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.oooo.2017.10.006_bib0205","first-page":"49","article-title":"Imatinib mesylate related oral mucosal pigmentation: two unusual cases","volume":"22","author":"Matziari","year":"2016","journal-title":"Oral Dis"},{"key":"10.1016\/j.oooo.2017.10.006_bib0210","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.tripleo.2011.03.046","article-title":"Are we ready to blame imatinib for palatal pigmentation?","volume":"112","author":"Torres-Pereira","year":"2011","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0215","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1111\/j.1468-3083.2008.02706.x","article-title":"Imatinib-associated hyperpigmentation, a side effect that should be recognized","volume":"23","author":"McPherson","year":"2009","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0220","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1097\/MPH.0b013e318033a76c","article-title":"Imatinib-induced dental hyperpigmentation in childhood chronic myeloid leukemia","volume":"29","author":"Singh","year":"2007","journal-title":"J Pediatr Hematol Oncol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0225","doi-asserted-by":"crossref","first-page":"685","DOI":"10.4103\/0253-7613.169576","article-title":"Imatinib-induced dental hyperpigmentation in chronic myeloid leukemia in an adult female","volume":"47","author":"Agrawal","year":"2015","journal-title":"Indian J Pharmacol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0230","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1046\/j.0307-6938.2001.00947.x","article-title":"Mucocutaneous adverse effects of hydroxyurea: a prospective study of 30 psoriasis patients","volume":"27","author":"Kumar","year":"2002","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0235","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.tripleo.2011.04.003","article-title":"Are we ready to blame imatinib for palatal pigmentation?","volume":"112","author":"Mattsson","year":"2011","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0240","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1111\/cup.12182","article-title":"Hard palate hyperpigmentation secondary to chronic chloroquine therapy: report of five cases","volume":"40","author":"de Andrade","year":"2013","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0245","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.tripleo.2008.07.022","article-title":"Pigmentation of the hard palate","volume":"107","author":"Lerman","year":"2009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.oooo.2017.10.006_bib0250","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1111\/j.1346-8138.2012.01591.x","article-title":"Hydroxychloroquine-induced hyperpigmentation","volume":"39","author":"Cho","year":"2012","journal-title":"J Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0255","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3109\/15569527.2010.521225","article-title":"Antimalarial cutaneous side effects: a study in 209 users","volume":"30","author":"Skare","year":"2011","journal-title":"Cutan Ocul Toxicol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0260","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1111\/j.1600-0560.2008.01004.x","article-title":"Hydroxychloroquine-induced hyperpigmentation: the staining pattern","volume":"35","author":"Puri","year":"2008","journal-title":"J Cutan Pathol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0265","first-page":"281","article-title":"Pigmentation of the gums following hydroxychloroquine therapy","volume":"49","author":"Veraldi","year":"1992","journal-title":"Cutis"},{"key":"10.1016\/j.oooo.2017.10.006_bib0270","first-page":"921","article-title":"Isolated hyperpigmentation of the oral mucosa due to hydroxychloroquine","volume":"10","author":"Kalampalikis","year":"2012","journal-title":"J Dtsch Dermatol Ges"},{"key":"10.1016\/j.oooo.2017.10.006_bib0275","doi-asserted-by":"crossref","first-page":"e266","DOI":"10.1111\/j.1365-2230.2008.03185.x","article-title":"Drug-induced pigmentation of hard palate and skin due to chronic chloroquine therapy: report of two cases","volume":"34","author":"Gallo","year":"2009","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0280","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1111\/bjd.14016","article-title":"Tumour necrosis factor-alpha inhibition can stabilize disease in progressive vitiligo","volume":"173","author":"Webb","year":"2015","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0285","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1111\/bjd.12779","article-title":"Melanoma associated with tumour necrosis factor-alpha inhibitors: a Research on Adverse Drug events And Reports (RADAR) project","volume":"170","author":"Nardone","year":"2014","journal-title":"Br J Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0290","doi-asserted-by":"crossref","first-page":"817","DOI":"10.2217\/imt.10.67","article-title":"Anti-TNF-alpha agents in the treatment of immune-mediated inflammatory diseases: mechanisms of action and pitfalls","volume":"2","author":"Silva","year":"2010","journal-title":"Immunotherapy"},{"key":"10.1016\/j.oooo.2017.10.006_bib0295","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1136\/annrheumdis-2013-204575","article-title":"Safety of synthetic and biological DMARDs: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis","volume":"73","author":"Ramiro","year":"2014","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.oooo.2017.10.006_bib0300","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1002\/art.22864","article-title":"Biologic treatment of rheumatoid arthritis and the risk of malignancy: analyses from a large US observational study","volume":"56","author":"Wolfe","year":"2007","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.oooo.2017.10.006_bib0305","doi-asserted-by":"crossref","first-page":"1895","DOI":"10.1136\/ard.2010.149419","article-title":"Malignancies associated with tumour necrosis factor inhibitors in registries and prospective observational studies: a systematic review and meta-analysis","volume":"70","author":"Mariette","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.oooo.2017.10.006_bib0310","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1053\/j.gastro.2012.05.004","article-title":"Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease","volume":"143","author":"Long","year":"2012","journal-title":"Gastroenterology"},{"key":"10.1016\/j.oooo.2017.10.006_bib0315","doi-asserted-by":"crossref","first-page":"e48991","DOI":"10.1371\/journal.pone.0048991","article-title":"Cancer risk of anti-TNF-alpha at recommended doses in adult rheumatoid arthritis: a meta-analysis with intention to treat and per protocol analyses","volume":"7","author":"Moulis","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1016\/j.oooo.2017.10.006_bib0320","doi-asserted-by":"crossref","first-page":"f1939","DOI":"10.1136\/bmj.f1939","article-title":"Rheumatoid arthritis, anti-tumour necrosis factor therapy, and risk of malignant melanoma: nationwide population based prospective cohort study from Sweden","volume":"346","author":"Raaschou","year":"2013","journal-title":"BMJ"},{"key":"10.1016\/j.oooo.2017.10.006_bib0325","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1111\/j.1365-2230.2008.02970.x","article-title":"Primary cutaneous melanoma: a complication of infliximab treatment?","volume":"34","author":"Khan","year":"2009","journal-title":"Clin Exp Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0330","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/1523-1747.ep12460991","article-title":"Interleukins 1 alpha and 6 and tumor necrosis factor-alpha are paracrine inhibitors of human melanocyte proliferation and melanogenesis","volume":"96","author":"Swope","year":"1991","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.oooo.2017.10.006_bib0335","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1746-160X-10-8","article-title":"Melanin: the biophysiology of oral melanocytes and physiological oral pigmentation","volume":"10","author":"Feller","year":"2014","journal-title":"Head Face Med"},{"key":"10.1016\/j.oooo.2017.10.006_bib0340","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/s12105-016-0693-x","article-title":"Melanoma of the oral cavity: an analysis of 46 new cases with emphasis on clinical and histopathologic characteristics","volume":"10","author":"Smith","year":"2016","journal-title":"Head Neck Pathol"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440317311458?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440317311458?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,8,6]],"date-time":"2022-08-06T10:52:42Z","timestamp":1659783162000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212440317311458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":67,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3]]}},"alternative-id":["S2212440317311458"],"URL":"https:\/\/doi.org\/10.1016\/j.oooo.2017.10.006","relation":{},"ISSN":["2212-4403"],"issn-type":[{"value":"2212-4403","type":"print"}],"subject":[],"published":{"date-parts":[[2018,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Drug-associated hyperpigmentation of the oral mucosa: report of four cases","name":"articletitle","label":"Article Title"},{"value":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.oooo.2017.10.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}