{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T15:33:17Z","timestamp":1792510397847,"version":"4.5.0"},"reference-count":37,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,6,1]],"date-time":"2021-06-01T00:00:00Z","timestamp":1622505600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oooojournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"published-print":{"date-parts":[[2021,6]]},"DOI":"10.1016\/j.oooo.2020.11.007","type":"journal-article","created":{"date-parts":[[2020,11,20]],"date-time":"2020-11-20T10:41:52Z","timestamp":1605868912000},"page":"702-710","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["HIV-positive patients with oral Kaposi's sarcoma: An overall survival analysis of 31 patients"],"prefix":"10.1016","volume":"131","author":[{"given":"Pablyanne Tereza Louzada","family":"Guedes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavia Sirotheau Correa","family":"Pontes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina","family":"Prado-Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leticia","family":"Rodrigues-Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tha\u00eds Bianca","family":"Brand\u00e3o","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas Lacerda","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9381-6409","authenticated-orcid":false,"given":"Barbara Waleria Gon\u00e7alves","family":"Alves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e1rcio Ajudarte","family":"Lopes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan Roger","family":"Santos-Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2156-0771","authenticated-orcid":false,"given":"Julius Caesar Mendes Soares","family":"Monteiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oslei Paes","family":"de Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lder Ant\u00f4nio Rebelo","family":"Pontes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.oooo.2020.11.007_bib0001","doi-asserted-by":"crossref","first-page":"182\u2010189","DOI":"10.1016\/j.jiph.2018.09.011","article-title":"Epidemiological trends and therapeutic challenges of malignancies in adult HIV-1-infected patients receiving combination antiretroviral therapy in a tertiary hospital from Romania: an observational retrospective study","volume":"12","author":"Gheorghi\u021b\u0103","year":"2019","journal-title":"J Infect Public Health"},{"key":"10.1016\/j.oooo.2020.11.007_bib0002","doi-asserted-by":"crossref","first-page":"1152\u20101159","DOI":"10.1016\/S1470-2045(09)70282-7","article-title":"Effect of immunodeficiency, HIV viral load, and antiretroviral therapy on the risk of individual malignancies (FHDH-ANRS CO4): a prospective cohort study","volume":"10","author":"Guiguet","year":"2009","journal-title":"Lancet Oncol"},{"key":"10.1016\/j.oooo.2020.11.007_bib0003","doi-asserted-by":"crossref","first-page":"133\u2010136","DOI":"10.1016\/j.canep.2018.04.001","article-title":"Neoplasms-associated deaths in HIV-1 infected and non-infected patients in Bahia, Brazil","volume":"54","author":"Marques","year":"2018","journal-title":"Cancer Epidemiol"},{"key":"10.1016\/j.oooo.2020.11.007_bib0004","doi-asserted-by":"crossref","first-page":"2551\u20102559","DOI":"10.1158\/1055-9965.EPI-11-0777","article-title":"HIV infection, immunodeficiency, viral replication, and the risk of cancer","volume":"20","author":"Silverberg","year":"2011","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"10.1016\/j.oooo.2020.11.007_bib0005","doi-asserted-by":"crossref","first-page":"3134\u20103146","DOI":"10.1002\/ijc.32895","article-title":"Cause-specific mortality after diagnosis of cancer among HIV-positive patients: a collaborative analysis of cohort studies","volume":"146","author":"Trickey","year":"2020","journal-title":"Int J Cancer"},{"key":"10.1016\/j.oooo.2020.11.007_bib0006","doi-asserted-by":"crossref","first-page":"1865\u20101869","DOI":"10.1126\/science.7997879","article-title":"Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma","volume":"266","author":"Chang","year":"1994","journal-title":"Science"},{"key":"10.1016\/j.oooo.2020.11.007_bib0007","doi-asserted-by":"crossref","first-page":"569\u2010577","DOI":"10.1097\/QAD.0000000000002450","article-title":"Kaposi sarcoma in people living with HIV: incidence and associated factors in a French cohort between 2010 and 2015","volume":"34","author":"Poizot-Martin","year":"2020","journal-title":"AIDS"},{"key":"10.1016\/j.oooo.2020.11.007_bib0008","doi-asserted-by":"crossref","first-page":"860\u2010869","DOI":"10.1080\/09540121.2015.1011074","article-title":"Trends in cancer diagnoses and survival among persons with AIDS in a high HIV prevalence urban area","volume":"27","author":"Castel","year":"2015","journal-title":"AIDS Care"},{"key":"10.1016\/j.oooo.2020.11.007_bib0009","first-page":"1\u201021","article-title":"AIDS-associated malignancies","volume":"177","author":"Vangipuram","year":"2019","journal-title":"Cancer Treat Res"},{"key":"10.1016\/j.oooo.2020.11.007_bib0010","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1056\/NEJMra1615896","article-title":"HIV-associated cancers and related diseases","volume":"378","author":"Yarchoan","year":"2018","journal-title":"N Engl J Med"},{"key":"10.1016\/j.oooo.2020.11.007_bib0011","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofu012","article-title":"Factors associated with cancer incidence and with all-cause mortality after cancer diagnosis among human immunodeficiency virus\u2013infected persons during the combination antiretroviral therapy era","volume":"1","author":"Patel","year":"2014","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.oooo.2020.11.007_bib0012","doi-asserted-by":"crossref","first-page":"2876\u20102882","DOI":"10.1200\/JCO.2003.10.162","volume":"21","author":"Nasti","year":"2003","journal-title":"J Clin Oncol"},{"key":"10.1016\/j.oooo.2020.11.007_bib0013","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1742-6405-7-19","article-title":"The impact of highly active antiretroviral therapy (HAART) on the clinical features of HIV-related oral lesions in Nigeria","volume":"7","author":"Taiwo","year":"2010","journal-title":"AIDS Res Ther"},{"key":"10.1016\/j.oooo.2020.11.007_bib0014","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/odi.13211","article-title":"A multicenter study of oral sarcomas in Brazil","volume":"26","author":"de Carvalho","year":"2020","journal-title":"Oral Dis"},{"key":"10.1016\/j.oooo.2020.11.007_bib0015","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1038\/sj.bjc.6603056","article-title":"Remission from Kaposi's sarcoma on HAART is associated with suppression of HIV replication and is independent of protease inhibitor therapy","volume":"94","author":"Martinez","year":"2006","journal-title":"Br J Cancer"},{"key":"10.1016\/j.oooo.2020.11.007_bib0016","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1056\/NEJMc070508","article-title":"HIV-associated Kaposi's sarcoma with a high CD4 count and a low viral load","volume":"357","author":"Maurer","year":"2007","journal-title":"N Engl J Med"},{"key":"10.1016\/j.oooo.2020.11.007_bib0017","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1097\/QAD.0b013e328317cc2d","article-title":"Trends in the incidence of cancers among HIV-infected persons and the impact of antiretroviral therapy: a 20-year cohort study","volume":"23","author":"Crum-Cianflone","year":"2009","journal-title":"AIDS"},{"key":"10.1016\/j.oooo.2020.11.007_bib0018","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1093\/aje\/kwm017","article-title":"The impact of highly active antiretroviral therapy on non-AIDS-defining cancers among adults with AIDS","volume":"165","author":"Hessol","year":"2007","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.oooo.2020.11.007_bib0019","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1038\/sj.bjc.6604520","article-title":"Kaposi sarcoma incidence in the Swiss HIV Cohort Study before and after highly active antiretroviral therapy","volume":"99","author":"Franceschi","year":"2008","journal-title":"Br J Cancer"},{"key":"10.1016\/j.oooo.2020.11.007_bib0020","doi-asserted-by":"crossref","first-page":"2990","DOI":"10.1002\/ijc.26332","article-title":"Ten-year survival among HIV-1-infected subjects with AIDS or non-AIDS-defining malignancies","volume":"130","author":"Spagnuolo","year":"2012","journal-title":"Int J Cancer"},{"key":"10.1016\/j.oooo.2020.11.007_bib0021","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1172\/JCI40567","article-title":"KSHV and the pathogenesis of Kaposi sarcoma: listening to human biology and medicine","volume":"120","author":"Ganem","year":"2010","journal-title":"J Clin Invest"},{"key":"10.1016\/j.oooo.2020.11.007_bib0022","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1097\/QAD.0000000000001573","article-title":"Incomplete viral suppression and mortality in HIV patients after antiretroviral therapy initiation","volume":"31","author":"Lee","year":"2017","journal-title":"AIDS"},{"key":"10.1016\/j.oooo.2020.11.007_bib0023","first-page":"335","article-title":"Baseline plasma viral load and CD4 cell percentage predict survival in HIV-1- and HIV-2-infected women in a community-based cohort in The Gambia","volume":"38","author":"Hansmann","year":"2005","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.oooo.2020.11.007_bib0024","doi-asserted-by":"crossref","first-page":"e5291","DOI":"10.1097\/MD.0000000000005291","article-title":"Genotypic distribution of HHV-8 in AIDS individuals without and with Kaposi sarcoma: is genotype B associated with better prognosis of AIDS-KS? [published correction appears in Medicine (Baltimore). 2017;96:e6992; Medicine (Baltimore). 2017;96:e6194]","volume":"95","author":"Tozetto-Mendoza","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.oooo.2020.11.007_bib0025","doi-asserted-by":"crossref","first-page":"2153","DOI":"10.1002\/jmv.21322","article-title":"HHV8 a subtype is associated with rapidly evolving classic Kaposi's sarcoma [published correction appears in J Med Virol. 2009;81:1128]","volume":"80","author":"Mancuso","year":"2008","journal-title":"J Med Virol"},{"key":"10.1016\/j.oooo.2020.11.007_bib0026","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcv.2020.104308","article-title":"Methods comparison for molecular diagnosis of human herpesvirus 8 infections","volume":"126","author":"Corgiat","year":"2020","journal-title":"J Clin Virol"},{"key":"10.1016\/j.oooo.2020.11.007_bib0027","doi-asserted-by":"crossref","first-page":"2109","DOI":"10.1097\/00002030-200009290-00006","article-title":"Relationship of human herpesvirus 8 peripheral blood virus load and Kaposi's sarcoma clinical stage","volume":"14","author":"Campbell","year":"2000","journal-title":"AIDS"},{"key":"10.1016\/j.oooo.2020.11.007_bib0028","doi-asserted-by":"crossref","first-page":"4269","DOI":"10.1128\/JCM.39.12.4269-4273.2001","article-title":"Viral load of human herpesvirus 8 in peripheral blood of human immunodeficiency virus\u2013infected patients with Kaposi's sarcoma","volume":"39","author":"Tedeschi","year":"2001","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.oooo.2020.11.007_bib0029","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1097\/00002030-200005260-00010","article-title":"Long-term efficacy on Kaposi's sarcoma of highly active antiretroviral therapy in a cohort of HIV-positive patients","volume":"14","author":"Dupont","year":"2000","journal-title":"AIDS"},{"key":"10.1016\/j.oooo.2020.11.007_bib0030","article-title":"CD4 cell count and the risk of AIDS or death in HIV-infected adults on combination antiretroviral therapy with a suppressed viral load: a longitudinal cohort study from COHERE","volume":"9","year":"2012","journal-title":"PLoS Med"},{"key":"10.1016\/j.oooo.2020.11.007_bib0031","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1093\/cid\/cir898","article-title":"AIDS and non-AIDS morbidity and mortality across the spectrum of CD4 cell counts in HIV-infected adults before starting antiretroviral therapy in Cote d'Ivoire","volume":"54","author":"Anglaret","year":"2012","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.oooo.2020.11.007_bib0032","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1002\/ijc.11601","article-title":"Nadir B cell counts are significantly correlated with the risk of Kaposi's sarcoma","volume":"108","author":"Stebbing","year":"2004","journal-title":"Int J Cancer"},{"key":"10.1016\/j.oooo.2020.11.007_bib0033","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1089\/aid.2019.0064","article-title":"CD4\/CD8 ratio and CD4 nadir predict mortality following noncommunicable disease diagnosis in adults living with HIV","volume":"35","author":"Castilho","year":"2019","journal-title":"AIDS Res Hum Retroviruses"},{"key":"10.1016\/j.oooo.2020.11.007_bib0034","doi-asserted-by":"crossref","first-page":"2644","DOI":"10.1002\/cncr.20309","article-title":"The changing pattern of Kaposi sarcoma in patients with HIV, 1994-2003: the EuroSIDA Study","volume":"100","author":"Mocroft","year":"2004","journal-title":"Cancer"},{"key":"10.1016\/j.oooo.2020.11.007_bib0035","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1097\/QAD.0000000000000071","article-title":"Malignancies in HIV\/AIDS: from epidemiology to therapeutic challenges","volume":"28","author":"Rubinstein","year":"2014","journal-title":"AIDS"},{"key":"10.1016\/j.oooo.2020.11.007_bib0036","doi-asserted-by":"crossref","first-page":"382\u2010390","DOI":"10.1097\/QAI.0000000000001394","article-title":"Association of CD4+ T-cell count, HIV-1 RNA viral load, and antiretroviral therapy with Kaposi sarcoma risk among HIV-infected persons in the United States and Canada","volume":"75","author":"Dubrow","year":"2017","journal-title":"J Acquir Immune Defic Syndr"},{"key":"10.1016\/j.oooo.2020.11.007_bib0037","series-title":"WHO Case Definitions of HIV for Surveillance and Revised Clinical Staging and Immunological Classification of HIV-Related Disease in Adults and Children","year":"2007"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440320313341?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440320313341?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T22:08:09Z","timestamp":1761948489000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212440320313341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2021,6]]}},"alternative-id":["S2212440320313341"],"URL":"https:\/\/doi.org\/10.1016\/j.oooo.2020.11.007","relation":{},"ISSN":["2212-4403"],"issn-type":[{"value":"2212-4403","type":"print"}],"subject":[],"published":{"date-parts":[[2021,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"HIV-positive patients with oral Kaposi's sarcoma: An overall survival analysis of 31 patients","name":"articletitle","label":"Article Title"},{"value":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.oooo.2020.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}