{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T20:24:31Z","timestamp":1767471871050,"version":"3.48.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","oooojournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.oooo.2025.08.021","type":"journal-article","created":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T17:22:24Z","timestamp":1757092944000},"page":"165-169","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Possible link between clostridioides difficile infection and oral mucositis: insights from a large real-world dataset"],"prefix":"10.1016","volume":"141","author":[{"given":"Stella O.","family":"Oyewole","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4602-9469","authenticated-orcid":false,"given":"Adepitan A.","family":"Owosho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"24","key":"10.1016\/j.oooo.2025.08.021_bib0001","first-page":"2369","article-title":"Emerging Infections Program CdST. Burden of Clostridium difficile infection in the United States","volume":"372","author":"Lessa","year":"2015","journal-title":"N Engl J Med"},{"issue":"14","key":"10.1016\/j.oooo.2025.08.021_bib0002","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1056\/NEJMoa1910215","article-title":"Trends in U.S. Burden of Clostridioides difficile Infection and Outcomes","volume":"382","author":"Guh","year":"2020","journal-title":"N Engl J Med"},{"issue":"19","key":"10.1016\/j.oooo.2025.08.021_bib0003","doi-asserted-by":"crossref","first-page":"5002","DOI":"10.1128\/JB.00542-10","article-title":"The human oral microbiome","volume":"192","author":"Dewhirst","year":"2010","journal-title":"J Bacteriol"},{"issue":"7285","key":"10.1016\/j.oooo.2025.08.021_bib0004","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1038\/nature08821","article-title":"A human gut microbial gene catalogue established by metagenomic sequencing","volume":"464","author":"Qin","year":"2010","journal-title":"Nature"},{"issue":"9","key":"10.1016\/j.oooo.2025.08.021_bib0005","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13092124","article-title":"Oral-gut microbiome axis in gastrointestinal disease and cancer","volume":"13","author":"Park","year":"2021","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.oooo.2025.08.021_bib0006","article-title":"The oral-gut microbiome axis in inflammatory bowel disease: from inside to insight","volume":"15","author":"Wang","year":"2024","journal-title":"Front Immunol"},{"year":"2025","series-title":"Extraintestinal Manifestations of Inflammatory Bowel Disease. StatPearls","author":"Malik","key":"10.1016\/j.oooo.2025.08.021_bib0007"},{"issue":"1","key":"10.1016\/j.oooo.2025.08.021_bib0008","doi-asserted-by":"crossref","DOI":"10.1080\/20002297.2023.2213112","article-title":"The interplay between oral microbiota, gut microbiota and systematic diseases","volume":"15","author":"Tan","year":"2023","journal-title":"J Oral Microbiol"},{"issue":"10","key":"10.1016\/j.oooo.2025.08.021_bib0009","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/j.bbmt.2013.07.022","article-title":"Clostridium difficile infection after adult autologous stem cell transplantation: a multicenter study of epidemiology and risk factors","volume":"19","author":"Alonso","year":"2013","journal-title":"Biol Blood Marrow Transplant"},{"issue":"2","key":"10.1016\/j.oooo.2025.08.021_bib0010","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.bbmt.2013.11.016","article-title":"Severe mucositis and Clostridium difficile infection in adult autologous stem cell recipients: another question of the chicken or the egg?","volume":"20","author":"Apewokin","year":"2014","journal-title":"Biol Blood Marrow Transplant"},{"issue":"Suppl 1","key":"10.1016\/j.oooo.2025.08.021_bib0011","doi-asserted-by":"crossref","first-page":"S214","DOI":"10.1093\/clinids\/6.Supplement_1.S214","article-title":"Inciting and etiologic agents of colitis","volume":"6","author":"Silva","year":"1984","journal-title":"Rev Infect Dis"},{"issue":"11","key":"10.1016\/j.oooo.2025.08.021_bib0012","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1016\/j.cmi.2023.07.008","article-title":"Clostridioides difficile infection-associated cause-specific and all-cause mortality: a population-based cohort study","volume":"29","author":"Boven","year":"2023","journal-title":"Clin Microbiol Infect"},{"issue":"18","key":"10.1016\/j.oooo.2025.08.021_bib0013","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.1056\/NEJMoa1012413","article-title":"Host and pathogen factors for Clostridium difficile infection and colonization","volume":"365","author":"Loo","year":"2011","journal-title":"N Engl J Med"},{"key":"10.1016\/j.oooo.2025.08.021_bib0014","doi-asserted-by":"crossref","DOI":"10.1016\/j.anaerobe.2021.102318","article-title":"Extraintestinal Clostridioides difficile infection: Septic arthritis 12 months after colitis","volume":"69","author":"Amaya","year":"2021","journal-title":"Anaerobe"},{"issue":"2","key":"10.1016\/j.oooo.2025.08.021_bib0015","first-page":"170","article-title":"Empyema caused by Clostridium difficile","volume":"10","author":"Hudson","year":"1999","journal-title":"Can J Infect Dis"},{"issue":"2","key":"10.1016\/j.oooo.2025.08.021_bib0016","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1097\/00005792-200103000-00002","article-title":"Extracolonic manifestations of Clostridium difficile infections. Presentation of 2 cases and review of the literature","volume":"80","author":"Jacobs","year":"2001","journal-title":"Medicine (Baltimore)"},{"issue":"6","key":"10.1016\/j.oooo.2025.08.021_bib0017","doi-asserted-by":"crossref","first-page":"e148","DOI":"10.1093\/cid\/cit392","article-title":"Extraintestinal Clostridium difficile infections","volume":"57","author":"Mattila","year":"2013","journal-title":"Clin Infect Dis"},{"issue":"2","key":"10.1016\/j.oooo.2025.08.021_bib0018","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2024-262106","article-title":"Extraintestinal Clostridium difficile infection presenting as spontaneous bacterial peritonitis","volume":"18","author":"Hafeez","year":"2025","journal-title":"BMJ Case Rep"},{"issue":"5","key":"10.1016\/j.oooo.2025.08.021_bib0019","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.ctrv.2007.03.001","article-title":"The role of pro-inflammatory cytokines in cancer treatment-induced alimentary tract mucositis: pathobiology, animal models and cytotoxic drugs","volume":"33","author":"Logan","year":"2007","journal-title":"Cancer Treat Rev"},{"issue":"1","key":"10.1016\/j.oooo.2025.08.021_bib0020","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1186\/s12967-020-02390-0","article-title":"Genome-wide association study identifies genetic susceptibility loci and pathways of radiation-induced acute oral mucositis","volume":"18","author":"Yang","year":"2020","journal-title":"J Transl Med"},{"key":"10.1016\/j.oooo.2025.08.021_bib0021","doi-asserted-by":"crossref","DOI":"10.3389\/fgene.2024.1397352","article-title":"Inside the genome: understanding genetic influences on oxidative stress","volume":"15","author":"Krishnamurthy","year":"2024","journal-title":"Front Genet"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440325012003?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2212440325012003?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,3]],"date-time":"2026-01-03T20:21:10Z","timestamp":1767471670000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2212440325012003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["S2212440325012003"],"URL":"https:\/\/doi.org\/10.1016\/j.oooo.2025.08.021","relation":{},"ISSN":["2212-4403"],"issn-type":[{"type":"print","value":"2212-4403"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Possible link between clostridioides difficile infection and oral mucositis: insights from a large real-world dataset","name":"articletitle","label":"Article Title"},{"value":"Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.oooo.2025.08.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}