{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:23:21Z","timestamp":1792653801604,"version":"4.5.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001826","name":"ZonMw","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001826","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aaojournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology"],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1016\/j.ophtha.2010.06.005","type":"journal-article","created":{"date-parts":[[2010,9,16]],"date-time":"2010-09-16T05:09:27Z","timestamp":1284613767000},"page":"302-309","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":137,"title":["Endothelial Cell Loss and Visual Outcome of Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty: A Randomized Multicenter Clinical Trial"],"prefix":"10.1016","volume":"118","clinical-trial-number":[{"clinical-trial-number":"isrctn02191620","registry":"10.18810\/isrctn"}],"author":[{"given":"Yanny Y.Y.","family":"Cheng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nienke","family":"Visser","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan S.","family":"Schouten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert-Jan","family":"Wijdh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth","family":"Pels","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"van Cleynenbreugel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catharina A.","family":"Eggink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel J.W.","family":"Zaal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wilhelmina J.","family":"Rijneveld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy M.M.A.","family":"Nuijts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ophtha.2010.06.005_bib1","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1007\/s00417-006-0390-7","article-title":"Impact of new lamellar techniques of keratoplasty on eye bank activity","volume":"245","author":"Muraine","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib2","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1136\/bjo.2005.086272","article-title":"Penetrating keratoplasty: outcomes from a corneal unit compared to national data","volume":"90","author":"Beckingsale","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib3","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/S0161-6420(03)00463-9","article-title":"Long-term graft survival after penetrating keratoplasty","volume":"110","author":"Thompson","year":"2003","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2010.06.005_bib4","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.ajo.2004.09.045","article-title":"Corneal endothelium and postoperative outcomes 15 years after penetrating keratoplasty","volume":"139","author":"Patel","year":"2005","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib5","first-page":"16","article-title":"Factors influencing the suitability of organ-cultured corneas for transplantation","volume":"38","author":"Armitage","year":"1997","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ophtha.2010.06.005_bib6","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1136\/bjo.81.3.184","article-title":"Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement","volume":"81","author":"Sugita","year":"1997","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib7","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.ajo.2006.10.043","article-title":"Quality of vision and graft thickness in deep anterior lamellar and penetrating corneal allografts","volume":"143","author":"Ardjomand","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib8","first-page":"217","article-title":"Deep lamellar keratoplasty dissection of host tissue with intrastromal air injection","volume":"3","author":"Archila","year":"1984","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2010.06.005_bib9","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1136\/bjo.76.11.646","article-title":"Deep lamellar keratoplasty on air with lyophilised tissue","volume":"76","author":"Chau","year":"1992","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib10","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1136\/bjo.83.3.327","article-title":"A new surgical technique for deep stromal, anterior lamellar keratoplasty","volume":"83","author":"Melles","year":"1999","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib11","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1097\/00003226-200205000-00009","article-title":"Deep lamellar keratoplasty: surgical techniques for anterior lamellar keratoplasty with and without baring of Descemet's membrane","volume":"21","author":"Anwar","year":"2002","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2010.06.005_bib12","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/S0886-3350(01)01181-6","article-title":"Big-bubble technique to bare Descemet's membrane in anterior lamellar keratoplasty","volume":"28","author":"Anwar","year":"2002","journal-title":"J Cataract Refract Surg"},{"key":"10.1016\/j.ophtha.2010.06.005_bib13","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1016\/j.ajo.2007.02.036","article-title":"Deep anterior lamellar keratoplasty by big-bubble technique for treatment corneal stromal opacities","volume":"143","author":"Vajpayee","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib14","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.ajo.2005.08.064","article-title":"Results of deep lamellar keratoplasty using the big-bubble technique in patients with keratoconus","volume":"141","author":"Fogla","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib15","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ajo.2006.09.025","article-title":"Clinical outcomes after deep anterior lamellar keratoplasty using the big-bubble technique in patients with keratoconus","volume":"143","author":"Fontana","year":"2007","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib16","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.ophtha.2008.12.043","article-title":"Outcomes of therapeutic deep lamellar keratoplasty and penetrating keratoplasty for advanced infectious keratitis: a comparative study","volume":"116","author":"Anshu","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2010.06.005_bib17","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/BF00154722","article-title":"Organ-culture preservation of human corneas","volume":"56","author":"Pels","year":"1983","journal-title":"Doc Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib18","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1097\/00003226-199903000-00005","article-title":"Deep lamellar keratoplasty versus penetrating keratoplasty for corneal lesions","volume":"18","author":"Panda","year":"1999","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2010.06.005_bib19","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1159\/000050894","article-title":"Deep lamellar keratoplasty","volume":"215","author":"Trimarchi","year":"2001","journal-title":"Ophthalmologica"},{"key":"10.1016\/j.ophtha.2010.06.005_bib20","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1016\/S0161-6420(98)91030-2","article-title":"Ten-year postoperative results of penetrating keratoplasty","volume":"105","author":"Ing","year":"1998","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2010.06.005_bib21","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/S0002-9394(02)01523-4","article-title":"Randomized clinical trial of deep lamellar keratoplasty vs penetrating keratoplasty","volume":"134","author":"Shimazaki","year":"2002","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib22","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1038\/eye.1998.155","article-title":"Corneal endothelial specular microscopy following deep lamellar keratoplasty with lyophilised tissue","volume":"12","author":"Morris","year":"1998","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.ophtha.2010.06.005_bib23","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1136\/bjo.67.11.751","article-title":"Endothelial cell loss in herpes zoster keratouveitis","volume":"67","author":"Reijo","year":"1983","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib24","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.ajo.2008.06.034","article-title":"Comparison of three different techniques of corneal transplantation for keratoconus","volume":"146","author":"Bahar","year":"2008","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib25","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1055\/s-2008-1027485","article-title":"Deep anterior lamellar (DALK) vs. penetrating keratoplasty (PKP): a clinical and statistical analysis","volume":"225","author":"Krumeich","year":"2008","journal-title":"Klin Monbl Augenheilkd"},{"key":"10.1016\/j.ophtha.2010.06.005_bib26","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1001\/archophthalmol.2007.12","article-title":"Comparison of techniques used for removing the recipient stroma in anterior lamellar keratoplasty","volume":"126","author":"Borderie","year":"2008","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib27","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.ajo.2003.09.053","article-title":"Endothelial cell density after deep anterior lamellar keratoplasty (Melles technique)","volume":"137","author":"van Dooren","year":"2004","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib28","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.ajo.2006.03.057","article-title":"Comparison of deep lamellar keratoplasty and penetrating keratoplasty for lattice and macular corneal dystrophies","volume":"142","author":"Kawashima","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib29","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1590\/S1807-59322007000600008","article-title":"Contrast sensitivity in deep anterior lamellar keratoplasty versus penetrating keratoplasty","volume":"62","author":"Silva","year":"2007","journal-title":"Clinics (Sao Paulo)"},{"key":"10.1016\/j.ophtha.2010.06.005_bib30","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1016\/j.ophtha.2004.02.010","article-title":"Comparison of deep lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus","volume":"111","author":"Watson","year":"2004","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2010.06.005_bib31","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/j.ajo.2009.05.028","article-title":"Comparison of outcomes of lamellar keratoplasty and penetrating keratoplasty in keratoconus","volume":"148","author":"Han","year":"2009","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2010.06.005_bib32","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1038\/sj.eye.6701903","article-title":"Comparative cohort study of the outcomes of deep lamellar keratoplasty and penetrating keratoplasty for keratoconus","volume":"20","author":"Funnell","year":"2006","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.ophtha.2010.06.005_bib33","first-page":"289","article-title":"Development of visual acuity and refraction in deep lamellar and penetrating keratoplasty (KPL)","volume":"223","author":"Low","year":"2006","journal-title":"Klin Monbl Augenheilkd"},{"key":"10.1016\/j.ophtha.2010.06.005_bib34","first-page":"408","article-title":"Deep anterior lamellar keratoplasty for keratoconus","volume":"25","author":"Al-Torbak","year":"2006","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2010.06.005_bib35","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/01.ico.0000240080.99832.f3","article-title":"Deep anterior lamellar keratoplasty (DALK): visual outcome and complications for a heterogeneous group of corneal pathologies","volume":"26","author":"Noble","year":"2007","journal-title":"Cornea"}],"container-title":["Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642010006068?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642010006068?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T13:59:48Z","timestamp":1758981588000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161642010006068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,2]]}},"alternative-id":["S0161642010006068"],"URL":"https:\/\/doi.org\/10.1016\/j.ophtha.2010.06.005","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.10502956.11344054","asserted-by":"object"}]},"ISSN":["0161-6420"],"issn-type":[{"value":"0161-6420","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Endothelial Cell Loss and Visual Outcome of Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty: A Randomized Multicenter Clinical Trial","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ophtha.2010.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}