{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:34:13Z","timestamp":1786995253759,"version":"build-2736575974"},"reference-count":48,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmology"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.ophtha.2011.08.002","type":"journal-article","created":{"date-parts":[[2011,12,10]],"date-time":"2011-12-10T05:14:14Z","timestamp":1323494054000},"page":"227-232","source":"Crossref","is-referenced-by-count":37,"title":["Randomized Trial of Pterygium Surgery with Mitomycin C Application Using Conjunctival Autograft versus Conjunctival-Limbal Autograft"],"prefix":"10.1016","volume":"119","author":[{"given":"Ahmad","family":"Kheirkhah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Hashemi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Adelpour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojgan","family":"Nikdel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Bagher","family":"Rajabi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud Jabbarvand","family":"Behrouz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ophtha.2011.08.002_bib1","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1136\/bjo.68.5.343","article-title":"Pterygium and ultraviolet radiation: a positive correlation","volume":"68","author":"Moran","year":"1984","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib2","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0039-6257(88)90071-9","article-title":"Pingueculae and pterygia","volume":"33","author":"Jaros","year":"1988","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib3","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/j.ajpath.2010.10.037","article-title":"Ophthalmic pterygium: a stem cell disorder with premalignant features","volume":"178","author":"Chui","year":"2011","journal-title":"Am J Pathol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib4","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1097\/00003226-199405000-00005","article-title":"A model for pterygium formation","volume":"13","author":"Kwok","year":"1994","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2011.08.002_bib5","doi-asserted-by":"crossref","first-page":"473","DOI":"10.3109\/02713689408999878","article-title":"Immunohistochemical evidence that human pterygia originate from an invasion of vimentin-expressing altered limbal epithelial basal cells","volume":"13","author":"Dushku","year":"1994","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.ophtha.2011.08.002_bib6","first-page":"595","article-title":"Classification of conjunctival surgeries for corneal diseases based on stem cell concept","volume":"3","author":"Tseng","year":"1990","journal-title":"Ophthalmol Clin North Am"},{"key":"10.1016\/j.ophtha.2011.08.002_bib7","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/S0161-6420(88)33104-0","article-title":"Mitomycin eye drops as treatment for pterygium","volume":"95","author":"Singh","year":"1988","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib8","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1016\/S0161-6420(91)32051-7","article-title":"Recurrence rate and complications after beta irradiation for pterygia","volume":"98","author":"MacKenzie","year":"1991","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib9","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1016\/0002-9394(73)90493-5","article-title":"Thio-TEPA therapy to prevent postoperative pterygium occurrence and neovascularization","volume":"76","author":"Kleis","year":"1973","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib10","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1097\/00055735-199908000-00010","article-title":"Conjunctival grafting for ocular surface disease","volume":"10","author":"Tan","year":"1999","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib11","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1097\/00055735-200208000-00003","article-title":"Management of primary and recurrent pterygium using amniotic membrane transplantation","volume":"13","author":"Ti","year":"2002","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib12","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/S0161-6420(97)30197-3","article-title":"Comparison of conjunctival autografts, amniotic membrane grafts, and primary closure for pterygium excision","volume":"104","author":"Prabhasawat","year":"1997","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib13","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1016\/S0161-6420(00)00567-4","article-title":"Amniotic membrane transplantation after extensive removal of primary and recurrent pterygia","volume":"108","author":"Solomon","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib14","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1016\/S0161-6420(85)33831-9","article-title":"Conjunctival autograft transplantation for advanced and recurrent pterygium","volume":"92","author":"Kenyon","year":"1985","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib15","doi-asserted-by":"crossref","first-page":"1612","DOI":"10.1016\/S0161-6420(89)32667-4","article-title":"A randomized trial of conjunctival autografting for pterygium in the tropics","volume":"96","author":"Lewallen","year":"1989","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib16","doi-asserted-by":"crossref","first-page":"875","DOI":"10.3928\/1542-8877-19971001-14","article-title":"Conjunctival autograft for pterygium surgery: how well does it prevent recurrence [letter]?","volume":"28","author":"Rao","year":"1997","journal-title":"Ophthalmic Surg Lasers"},{"key":"10.1016\/j.ophtha.2011.08.002_bib17","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0002-9394(14)72602-9","article-title":"A randomized trial comparing mitomycin C and conjunctival autograft after excision of primary pterygium","volume":"120","author":"Chen","year":"1995","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib18","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1136\/bjo.2006.095018","article-title":"Randomised controlled study of conjunctival autograft versus amniotic membrane graft in pterygium excision","volume":"90","author":"Luanratanakorn","year":"2006","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib19","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1177\/112067219800800305","article-title":"Different therapeutic approaches and outcome in the treatment of pterygium","volume":"8","author":"Karabatsas","year":"1998","journal-title":"Eur J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib20","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1001\/archopht.1997.01100160405001","article-title":"Effect of pterygium morphology on pterygium recurrence in a controlled trial comparing conjunctival autografting with bare sclera excision","volume":"115","author":"Tan","year":"1997","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib21","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0161-6420(89)32833-8","article-title":"Limbal autograft transplantation for ocular surface disorders","volume":"96","author":"Kenyon","year":"1989","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib22","first-page":"143","article-title":"The pterygium, autologous conjunctiva-limbus transplantation as treatment [in German]","volume":"89","author":"Koch","year":"1992","journal-title":"Ophthalmologe"},{"key":"10.1016\/j.ophtha.2011.08.002_bib23","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1016\/S0161-6420(02)01160-0","article-title":"Limbal versus conjunctival autograft transplantation for advanced and recurrent pterygium","volume":"109","author":"Al Fayez","year":"2002","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib24","doi-asserted-by":"crossref","first-page":"917","DOI":"10.3928\/1542-8877-19961101-05","article-title":"Limbal autograft transplantation for recurrent and advanced pterygia","volume":"27","author":"Shimazaki","year":"1996","journal-title":"Ophthalmic Surg Lasers"},{"key":"10.1016\/j.ophtha.2011.08.002_bib25","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1016\/S0161-6420(99)90172-0","article-title":"A comparative study of recurrent pterygium surgery: limbal conjunctival autograft transplantation versus mitomycin C with conjunctival flap","volume":"106","author":"Mutlu","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib26","first-page":"203","article-title":"Conjunctival-limbal autografts for primary and recurrent pterygia: technique and results","volume":"46","author":"Rao","year":"1998","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib27","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/ICO.0b013e31815873da","article-title":"Role of conjunctival inflammation in surgical outcome after amniotic membrane transplantation with or without fibrin glue for pterygium","volume":"27","author":"Kheirkhah","year":"2008","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2011.08.002_bib28","doi-asserted-by":"crossref","first-page":"1512","DOI":"10.1016\/S0161-6420(99)90445-1","article-title":"Use of mitomycin C with conjunctival autograft in pterygium surgery in Asian-Canadians","volume":"106","author":"Wong","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib29","doi-asserted-by":"crossref","first-page":"662","DOI":"10.3928\/1542-8877-19970801-09","article-title":"Topical mitomycin C for pterygia: is single application appropriate?","volume":"28","author":"Rubinfeld","year":"1997","journal-title":"Ophthalmic Surg Lasers"},{"key":"10.1016\/j.ophtha.2011.08.002_bib30","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/00003226-200310000-00003","article-title":"Combined mitomycin C application and free flap conjunctival autograft in pterygium surgery","volume":"22","author":"Segev","year":"2003","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2011.08.002_bib31","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1007\/s10792-007-9085-2","article-title":"Mitomycin C and conjunctival autograft for recurrent pterygium","volume":"27","author":"Altiparmak","year":"2007","journal-title":"Int Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib32","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1080\/01676830600972724","article-title":"Comparison of three methods for the treatment of pterygium: amniotic membrane graft, conjunctival autograft and conjunctival autograft plus mitomycin C","volume":"26","author":"Katircio\u011flu","year":"2007","journal-title":"Orbit"},{"key":"10.1016\/j.ophtha.2011.08.002_bib33","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.ajo.2005.12.028","article-title":"Conjunctival autografting combined with low-dose mitomycin C for prevention of primary pterygium recurrence","volume":"141","author":"Frucht-Pery","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib34","doi-asserted-by":"crossref","first-page":"193","DOI":"10.3928\/1542-8877-20030501-05","article-title":"Evaluation of limbal conjunctival autograft and low-dose mitomycin C in the treatment of recurrent pterygium","volume":"34","author":"Nabawi","year":"2003","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"10.1016\/j.ophtha.2011.08.002_bib35","doi-asserted-by":"crossref","first-page":"123","DOI":"10.2147\/OPTH.S16474","article-title":"The use of mitomycin C with autologous limbal-conjunctival autograft transplantation for management of recurrent pterygium","volume":"5","author":"Fakhry","year":"2011","journal-title":"Clin Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib36","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1136\/bjo.79.5.439","article-title":"Prospective trial of intraoperative mitomycin C in the treatment of primary pterygium","volume":"79","author":"Cano-Parra","year":"1995","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib37","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/S0161-6420(97)30224-3","article-title":"Intraoperative mitomycin C in primary pterygium excision: a controlled randomized trial","volume":"104","author":"Manning","year":"1997","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib38","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/00003226-200101000-00004","article-title":"Low-dose intraoperative mitomycin C as chemoadjuvant for pterygium surgery","volume":"20","author":"Cheng","year":"2001","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2011.08.002_bib39","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1097\/00003226-200103000-00005","article-title":"Impression cytology-proven corneal stem cell deficiency in patients after surgeries involving the limbus","volume":"20","author":"Sridhar","year":"2001","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2011.08.002_bib40","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0161-6420(99)00041-X","article-title":"Limbal-conjunctival autograft transplantation for the treatment of recurrent pterygium","volume":"107","author":"Gris","year":"2000","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib41","unstructured":"Kheirkhah A, Nazari R, Nikdel M, et al. Postoperative conjunctival inflammation after pterygium surgery with amniotic membrane transplantation versus conjunctival autograft. Am J Ophthalmol. In press."},{"key":"10.1016\/j.ophtha.2011.08.002_bib42","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/01.ICL.0000140908.17491.A0","article-title":"Safety and efficacy of the technique of complete Tenon's membrane excision and mitomycin C in pterygium surgery","volume":"31","author":"Levy","year":"2005","journal-title":"Eye Contact Lens"},{"key":"10.1016\/j.ophtha.2011.08.002_bib43","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1080\/02713680802045099","article-title":"Extensive versus limited pterygium excision with conjunctival autograft: outcomes and recurrence rates","volume":"33","author":"Bahar","year":"2008","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.ophtha.2011.08.002_bib44","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.1016\/j.ophtha.2008.03.012","article-title":"Prospective study of primary pterygium surgery using pterygium extended removal followed by extended conjunctival transplantation","volume":"115","author":"Hirst","year":"2008","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib45","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1016\/S0161-6420(92)31749-X","article-title":"Serious complications of topical mitomycin-C after pterygium surgery","volume":"99","author":"Rubinfeld","year":"1992","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2011.08.002_bib46","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/S0002-9394(14)76738-8","article-title":"Development of scleral ulceration and calcification after pterygium excision and mitomycin therapy [letter]","volume":"112","author":"Dunn","year":"1991","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2011.08.002_bib47","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1159\/000310424","article-title":"Corneoscleral ulceration and cornea1 perforation after pterygium excision and topical mitomycin C therapy","volume":"207","author":"Fujitani","year":"1993","journal-title":"Ophthalmologica"},{"key":"10.1016\/j.ophtha.2011.08.002_bib48","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1097\/00004397-199903920-00007","article-title":"Ocular toxicity of mitomycin-C","volume":"39","author":"Hardten","year":"1999","journal-title":"Int Ophthalmol Clin"}],"container-title":["Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642011007469?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642011007469?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,12,19]],"date-time":"2021-12-19T12:15:48Z","timestamp":1639916148000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161642011007469"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":48,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0161642011007469"],"URL":"https:\/\/doi.org\/10.1016\/j.ophtha.2011.08.002","relation":{},"ISSN":["0161-6420"],"issn-type":[{"value":"0161-6420","type":"print"}],"subject":[],"published":{"date-parts":[[2012,2]]}}}