{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T19:33:37Z","timestamp":1786995217061,"version":"build-2736575974"},"reference-count":37,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","aaojournal.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.ophtha.2015.04.031","type":"journal-article","created":{"date-parts":[[2015,6,4]],"date-time":"2015-06-04T21:14:04Z","timestamp":1433452444000},"page":"1653-1659","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"title":["Anatomic Predictive Factors of Acute Corneal Hydrops in Keratoconus"],"prefix":"10.1016","volume":"122","author":[{"given":"Esteban","family":"Fuentes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9133-5786","authenticated-orcid":false,"given":"Otman","family":"Sandali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"El Sanharawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Basli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taous","family":"Hamiche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Goemaere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Borderie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nacim","family":"Bouheraoua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laurent","family":"Laroche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ophtha.2015.04.031_bib1","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1016\/S0161-6420(94)31110-9","article-title":"Acute corneal hydrops in keratoconus","volume":"101","author":"Tuft","year":"1994","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib2","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1016\/j.ophtha.2010.09.030","article-title":"Intracameral perfluoropropane gas in the treatment of acute corneal hydrops","volume":"118","author":"Basu","year":"2011","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib3","first-page":"187","article-title":"Acute hydrops in the corneal ectasias: associated factors and outcomes","volume":"97","author":"Grewal","year":"1999","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.ophtha.2015.04.031_bib4","first-page":"331","article-title":"Quelques donn\u00e9es du probl\u00e8me du k\u00e9ratoc\u00f4ne","volume":"128","author":"Amsler","year":"1961","journal-title":"Bull Soc Belge Ophtalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib5","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1097\/ICO.0b013e31818cd077","article-title":"Clinical profile and risk factors for keratoplasty and development of hydrops in north Indian patients with keratoconus","volume":"28","author":"Sharma","year":"2009","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2015.04.031_bib6","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1136\/bjo.87.1.120","article-title":"Acute keratoconus with perforation in a patient with Down\u2019s syndrome","volume":"87","author":"Stoiber","year":"2003","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib7","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3928\/1081-597X-19930901-11","article-title":"Keratoconus and corneal hydrops associated with compulsive eye rubbing","volume":"9","author":"Koenig","year":"1993","journal-title":"Refract Corneal Surg"},{"key":"10.1016\/j.ophtha.2015.04.031_bib8","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1016\/S0161-6420(95)30755-5","article-title":"Corneal hydrops associated with vernal conjunctivitis as a presenting sign of keratoconus in children","volume":"102","author":"Rehany","year":"1995","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib9","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1097\/ICO.0b013e31813e0bc6","article-title":"Deep lamellar keratoplasty in keratoconus with healed hydrops","volume":"26","author":"Das","year":"2007","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2015.04.031_bib10","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1097\/ICO.0b013e3181f0b1f3","article-title":"Deep lamellar keratoplasty after resolution of hydrops in keratoconus","volume":"30","author":"Chew","year":"2011","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2015.04.031_bib11","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/j.ajo.2014.01.017","article-title":"Acute corneal hydrops in keratoconus - new perspectives","volume":"157","author":"Fan Gaskin","year":"2014","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib12","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1016\/j.ophtha.2013.12.017","article-title":"A\u00a0comparison of lamellar and penetrating keratoplasty outcome: a registry study","volume":"121","author":"Coster","year":"2014","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib13","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.ophtha.2011.07.057","article-title":"Long-term results of deep anterior lamellar versus penetrating keratoplasty","volume":"119","author":"Borderie","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib14","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.ajo.2011.01.007","article-title":"Graft rejection and graft failure after anterior lamellar versus penetrating keratoplasty","volume":"151","author":"Borderie","year":"2011","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib15","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1016\/j.ophtha.2013.05.027","article-title":"Fourier-domain optical coherence tomography imaging in keratoconus: a corneal structural classification","volume":"120","author":"Sandali","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib16","doi-asserted-by":"crossref","first-page":"461","DOI":"10.4103\/0301-4738.116062","article-title":"Acute corneal hydrops in keratoconus","volume":"61","author":"Maharana","year":"2013","journal-title":"Indian J Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib17","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/ICO.0b013e318223988e","article-title":"Anterior segment optical coherence tomography features of acute corneal hydrops","volume":"31","author":"Basu","year":"2012","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2015.04.031_bib18","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.jfo.2014.04.008","article-title":"\u201cEn face\u201d anterior segment optical coherence tomography findings in acute corneal hydrops","volume":"37","author":"Kallel","year":"2014","journal-title":"J\u00a0Fr Ophtalmol"},{"issue":"suppl","key":"10.1016\/j.ophtha.2015.04.031_bib19","doi-asserted-by":"crossref","first-page":"114","DOI":"10.3928\/15428877-20101031-12","article-title":"Anterior segment optical coherence tomography findings of acute hydrops in a patient with keratoconus","volume":"41","author":"Kucumen","year":"2010","journal-title":"Ophthalmic Surg Lasers Imaging"},{"key":"10.1016\/j.ophtha.2015.04.031_bib20","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1159\/000337483","article-title":"Imaging of a severe case of acute hydrops in a patient with keratoconus using anterior segment optical coherence tomography","volume":"3","author":"Ueno","year":"2012","journal-title":"Case Rep Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib21","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1016\/j.ophtha.2012.06.062","article-title":"Acute corneal hydrops","volume":"119","author":"Basu","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib22","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3928\/1081597X-20090401-07","article-title":"Circular keratotomy to reduce astigmatism and improve vision in stage I and II keratoconus","volume":"25","author":"Krumeich","year":"2009","journal-title":"J\u00a0Refract Surg"},{"key":"10.1016\/j.ophtha.2015.04.031_bib23","doi-asserted-by":"crossref","first-page":"1296","DOI":"10.1136\/bjophthalmol-2013-304145","article-title":"A\u00a0prospective study of acute corneal hydrops by in\u00a0vivo confocal microscopy in a New Zealand population with keratoconus","volume":"98","author":"Lockington","year":"2014","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib24","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/0002-9394(56)90654-7","article-title":"Histopathology of keratoconus","volume":"42","author":"Chi","year":"1956","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib25","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/j.1444-0938.2007.00195.x","article-title":"New perspectives on keratoconus as revealed by corneal confocal microscopy","volume":"91","author":"Efron","year":"2008","journal-title":"Clin Exp Optom"},{"key":"10.1016\/j.ophtha.2015.04.031_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0016437","article-title":"Subnormal cytokine profile in the tear fluid of keratoconus patients","author":"Jun","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.ophtha.2015.04.031_bib27","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1006\/exer.1996.0038","article-title":"Epithelial injury induces keratocyte apoptosis: hypothesized role for the interleukin-1 system in the modulation of corneal tissue organization and wound healing","volume":"62","author":"Wilson","year":"1996","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.ophtha.2015.04.031_bib28","doi-asserted-by":"crossref","first-page":"585","DOI":"10.3109\/02713689109013850","article-title":"Binding sites for human interleukin 1 alpha, gamma interferon and tumor necrosis factor on cultured fibroblasts of normal cornea and keratoconus","volume":"10","author":"Fabre","year":"1991","journal-title":"Curr Eye Res"},{"key":"10.1016\/j.ophtha.2015.04.031_bib29","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1016\/j.ophtha.2004.11.050","article-title":"Inflammatory molecules in the tears of patients with keratoconus","volume":"112","author":"Lema","year":"2005","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib30","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1136\/bjo.85.4.437","article-title":"The specific architecture of the anterior stroma accounts for maintenance of corneal curvature","volume":"85","author":"M\u00fcller","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2015.04.031_bib31","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0014-4835(90)90011-I","article-title":"Cohesive strength of corneal lamellae","volume":"50","author":"Maurice","year":"1990","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.ophtha.2015.04.031_bib32","doi-asserted-by":"crossref","first-page":"604","DOI":"10.3928\/1081597X-20090610-06","article-title":"Corneal epithelial thickness profile in the diagnosis of keratoconus","volume":"25","author":"Reinstein","year":"2009","journal-title":"J\u00a0Refract Surg"},{"key":"10.1016\/j.ophtha.2015.04.031_bib33","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3928\/1081597X-20100218-01","article-title":"Epithelial, stromal, and total corneal thickness in keratoconus: three-dimensional display with artemis very-high frequency digital ultrasound","volume":"26","author":"Reinstein","year":"2010","journal-title":"J\u00a0Refract Surg"},{"key":"10.1016\/j.ophtha.2015.04.031_bib34","doi-asserted-by":"crossref","first-page":"2425","DOI":"10.1016\/j.ophtha.2012.06.023","article-title":"Corneal epithelial thickness mapping by Fourier-domain optical coherence tomography in normal and keratoconic eyes","volume":"119","author":"Li","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib35","doi-asserted-by":"crossref","first-page":"486","DOI":"10.3928\/1081-597X-20060501-11","article-title":"Corneal and epithelial thickness in keratoconus: a comparison of ultrasonic pachymetry, Orbscan II, and optical coherence tomography","volume":"22","author":"Haque","year":"2006","journal-title":"J\u00a0Refract Surg"},{"key":"10.1016\/j.ophtha.2015.04.031_bib36","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/PAT.0b013e3283511b42","article-title":"An in depth analysis of histopathological characteristics found in keratoconus","volume":"44","author":"Sykakis","year":"2012","journal-title":"Pathology"},{"key":"10.1016\/j.ophtha.2015.04.031_bib37","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/0002-9394(76)90494-3","article-title":"Ultrastructure of keratoconus with healed hydrops","volume":"82","author":"Stone","year":"1976","journal-title":"Am J Ophthalmol"}],"container-title":["Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642015004133?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642015004133?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,11]],"date-time":"2022-05-11T00:32:09Z","timestamp":1652229129000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161642015004133"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":37,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S0161642015004133"],"URL":"https:\/\/doi.org\/10.1016\/j.ophtha.2015.04.031","relation":{},"ISSN":["0161-6420"],"issn-type":[{"value":"0161-6420","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Anatomic Predictive Factors of Acute Corneal Hydrops in Keratoconus","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ophtha.2015.04.031","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}