{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T14:50:00Z","timestamp":1758639000433,"version":"3.40.5"},"reference-count":31,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","aaojournal.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.ophtha.2016.08.018","type":"journal-article","created":{"date-parts":[[2016,9,22]],"date-time":"2016-09-22T03:16:57Z","timestamp":1474514217000},"page":"2481-2488","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Corneal Epithelial Stem Cells Repopulate the Donor Area within 1 Year from Limbus Removal for Limbal Autograft"],"prefix":"10.1016","volume":"123","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3635-3521","authenticated-orcid":false,"given":"Massimo","family":"Busin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Breda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marina","family":"Bertolin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Bovone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego","family":"Ponzin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Ferrari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"Barbaro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hossein Mostafa","family":"Elbadawy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ophtha.2016.08.018_bib1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1136\/bjo.84.3.273","article-title":"Autologous limbal transplantation in patients with unilateral corneal stem cell deficiency","volume":"84","author":"Dua","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2016.08.018_bib2","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1016\/S0161-6420(83)80056-6","article-title":"Conjunctival autograft transplantation for unilateral ocular surface diseases","volume":"90","author":"Herman","year":"1983","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2016.08.018_bib3","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1159\/000417087","article-title":"Limbal autograft transplantation for chemical and thermal burns","volume":"18","author":"Kenyon","year":"1989","journal-title":"Dev Ophthalmol"},{"key":"10.1016\/j.ophtha.2016.08.018_bib4","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1055\/s-2008-1035508","article-title":"Modified technique of autologous conjunctival transplantation after corneal chemical burn","volume":"204","author":"M\u00f6nks","year":"1994","journal-title":"Klin Monbl Augenheilkd"},{"key":"10.1016\/j.ophtha.2016.08.018_bib5","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1097\/00003226-200307000-00016","article-title":"Use of autologous cultured limbal and conjunctival epithelium in a patient with severe bilateral ocular surface disease induced by acid injury: a case report of unique application","volume":"22","author":"Sangwan","year":"2003","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2016.08.018_bib6","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1001\/archopht.1977.04450080135017","article-title":"Conjunctival transplantation","volume":"95","author":"Thoft","year":"1977","journal-title":"Arch Ophtalmol"},{"key":"10.1016\/j.ophtha.2016.08.018_bib7","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/S0161-6420(79)35433-1","article-title":"Conjunctival transplantation as an alternative to keratoplasty","volume":"86","author":"Thoft","year":"1979","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2016.08.018_bib8","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1056\/NEJM200007133430202","article-title":"Reconstruction of damaged corneas by transplantation of autologous limbal epithelial cells","volume":"343","author":"Tsai","year":"2000","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ophtha.2016.08.018_bib9","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/S1542-0124(12)70225-2","article-title":"Techniques for culture and assessment of limbal stem cell grafts","volume":"8","author":"Di Iorio","year":"2010","journal-title":"Ocul Surf"},{"key":"10.1016\/j.ophtha.2016.08.018_bib10","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1016\/S0140-6736(96)11188-0","article-title":"Long-term restoration of damaged corneal surfaces with autologous cultivated corneal epithelium","volume":"349","author":"Pellegrini","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.ophtha.2016.08.018_bib11","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0161-6420(89)32833-8","article-title":"Limbal autograft transplantation for ocular surface disorders","volume":"96","author":"Kenyon","year":"1989","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2016.08.018_bib12","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1002\/jemt.20375","article-title":"Q-FIHC: quantification of fluorescence immunohistochemistry to analyse p63 isoforms and cell cycle phases in human limbal stem cells","volume":"69","author":"Di Iorio","year":"2006","journal-title":"Microsc Res Tech"},{"key":"10.1016\/j.ophtha.2016.08.018_bib13","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1083\/jcb.145.4.769","article-title":"Location and clonal analysis of stem cells and their differentiated progeny in the human ocular surface","volume":"145","author":"Pellegrini","year":"1999","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.ophtha.2016.08.018_bib14","doi-asserted-by":"crossref","first-page":"3156","DOI":"10.1073\/pnas.061032098","article-title":"p63 identifies keratinocyte stem cells","volume":"98","author":"Pellegrini","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ophtha.2016.08.018_bib15","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1167\/iovs.05-0343","article-title":"High expression of p63 combined with a large N\/C ratio defines a subset of human limbal epithelial cells: implications on epithelial stem cells","volume":"46","author":"Arpitha","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ophtha.2016.08.018_bib16","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1634\/stemcells.22-3-355","article-title":"Characterization of putative stem cell phenotype in human limbal epithelia","volume":"22","author":"Chen","year":"2004","journal-title":"Stem Cells"},{"key":"10.1016\/j.ophtha.2016.08.018_bib17","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1634\/stemcells.2005-0148","article-title":"Cell size correlates with phenotype and proliferative capacity in human corneal epithelial cells","volume":"24","author":"De Paiva","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.ophtha.2016.08.018_bib18","doi-asserted-by":"crossref","first-page":"9523","DOI":"10.1073\/pnas.0503437102","article-title":"Isoforms of DeltaNp63 and the migration of ocular limbal cells in human corneal regeneration","volume":"102","author":"Di Iorio","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.ophtha.2016.08.018_bib19","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1136\/bjo.2009.164152","article-title":"Evaluation of ocular surface disorders: a new diagnostic tool based on impression cytology and confocal laser scanning microscopy","volume":"94","author":"Barbaro","year":"2010","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.ophtha.2016.08.018_bib20","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1101\/gad.1165104","article-title":"p63 is the molecular switch for initiation of an epithelial stratification program","volume":"18","author":"Koster","year":"2004","journal-title":"Genes Dev"},{"key":"10.1016\/j.ophtha.2016.08.018_bib21","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1056\/NEJMoa0905955","article-title":"Limbal stem-cell therapy and long-term corneal regeneration","volume":"363","author":"Rama","year":"2010","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.ophtha.2016.08.018_bib22","first-page":"1301","article-title":"Corneal epithelial wound healing in partial limbal deficiency","volume":"31","author":"Chen","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ophtha.2016.08.018_bib23","first-page":"1903","article-title":"Conjunctival transdifferentiation is due to incomplete removal of limbal basal epithelium","volume":"31","author":"Kruse","year":"1990","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ophtha.2016.08.018_bib24","first-page":"96","article-title":"Corneal epithelial wound healing in the absence of limbal epithelium","volume":"32","author":"Huang","year":"1991","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ophtha.2016.08.018_bib25","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/S0161-6420(99)90173-2","article-title":"Limbal allografting from related live donors for corneal surface reconstruction","volume":"106","author":"Rao","year":"1999","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2016.08.018_bib26","first-page":"378","article-title":"Limbal stem cell transplantation from HLA-compatible living donors. Long term observation","volume":"105","author":"Wylegala","year":"2003","journal-title":"Klin Oczna"},{"key":"10.1016\/j.ophtha.2016.08.018_bib27","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1159\/000086115","article-title":"Limbal graft and\/or amniotic membrane transplantation in the treatment of ocular burns","volume":"219","author":"Ivekovic","year":"2005","journal-title":"Ophthalmologica"},{"key":"10.1016\/j.ophtha.2016.08.018_bib28","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1007\/s00417-006-0453-9","article-title":"The long-term safety of donor eye for 180 degrees limbal transplantation","volume":"245","author":"Han","year":"2007","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.ophtha.2016.08.018_bib29","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1590\/S0004-27492011000400003","article-title":"Cytological features of live limbal tissue donor eyes for autograft or allograft limbal stem cell transplantation","volume":"74","author":"Barros J de","year":"2011","journal-title":"Arq Bras Oftalmol"},{"key":"10.1016\/j.ophtha.2016.08.018_bib30","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1016\/j.ophtha.2010.11.030","article-title":"Donor site complications in autolimbal\u00a0and living-related allolimbal transplantation","volume":"118","author":"Miri","year":"2011","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2016.08.018_bib31","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1016\/j.ophtha.2008.12.017","article-title":"The role of limbal stem cells in corneal epithelial maintenance: testing the dogma","volume":"116","author":"Dua","year":"2009","journal-title":"Ophthalmology"}],"container-title":["Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642016309319?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642016309319?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T06:17:21Z","timestamp":1692512241000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161642016309319"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S0161642016309319"],"URL":"https:\/\/doi.org\/10.1016\/j.ophtha.2016.08.018","relation":{},"ISSN":["0161-6420"],"issn-type":[{"type":"print","value":"0161-6420"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Corneal Epithelial Stem Cells Repopulate the Donor Area within 1 Year from Limbus Removal for Limbal Autograft","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ophtha.2016.08.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 by the American Academy of Ophthalmology","name":"copyright","label":"Copyright"}]}}