{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:49:08Z","timestamp":1789753748259,"version":"4.0.1"},"reference-count":7,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,2,1]],"date-time":"2020-02-01T00:00:00Z","timestamp":1580515200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,9,26]],"date-time":"2019-09-26T00:00:00Z","timestamp":1569456000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000921","name":"European Cooperation in Science and Technology","doi-asserted-by":"publisher","award":["CA18116"],"award-info":[{"award-number":["CA18116"]}],"id":[{"id":"10.13039\/501100000921","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aaojournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology"],"published-print":{"date-parts":[[2020,2]]},"DOI":"10.1016\/j.ophtha.2019.09.034","type":"journal-article","created":{"date-parts":[[2019,9,28]],"date-time":"2019-09-28T01:41:41Z","timestamp":1569634901000},"page":"273-275","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"title":["PAX6 Mutational Status Determines Aniridia-Associated Keratopathy Phenotype"],"prefix":"10.1016","volume":"127","author":[{"given":"Neil","family":"Lagali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bogumil","family":"Wowra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8526-4712","authenticated-orcid":false,"given":"Fabian Norbert","family":"Fries","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenz","family":"Latta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayed","family":"Moslemani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tor Paaske","family":"Utheim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Wylegala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"K\u00e4smann-Kellner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ophtha.2019.09.034_bib1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1046\/j.1365-2443.1996.11011.x","article-title":"The master control gene for morphogenesis and evolution of the eye","volume":"1","author":"Gehring","year":"1996","journal-title":"Genes Cells"},{"key":"10.1016\/j.ophtha.2019.09.034_bib2","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1016\/j.ophtha.2011.12.010","article-title":"Comparison between aniridia with and without PAX6 mutations: clinical and molecular analysis in 14 Korean patients with aniridia","volume":"119","author":"Lim","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2019.09.034_bib3","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1167\/iovs.08-2827","article-title":"Detailed ophthalmologic evaluation of 43 individuals with PAX6 mutations","volume":"50","author":"Hingorani","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ophtha.2019.09.034_bib4","doi-asserted-by":"crossref","first-page":"306","DOI":"10.3109\/08820538.2013.825293","article-title":"A\u00a0review of the clinical and genetic aspects of aniridia","volume":"28","author":"Lee","year":"2013","journal-title":"Semin Ophthalmol"},{"key":"10.1016\/j.ophtha.2019.09.034_bib5","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jtos.2017.11.003","article-title":"Stage-related central corneal epithelial transformation in congenital aniridia-associated keratopathy","volume":"16","author":"Lagali","year":"2018","journal-title":"Ocul Surf"},{"key":"10.1016\/j.ophtha.2019.09.034_bib6","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/j.ajo.2006.06.057","article-title":"Epithelial dendritic cell distribution in normal and inflamed human cornea: in\u00a0vivo confocal microscopy study","volume":"142","author":"Mastropasqua","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2019.09.034_bib7","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1007\/s00347-014-3060-x","article-title":"Aniridia syndrome: clinical findings, problematic courses and suggestions for optimization of care (aniridia guide) [in German]","volume":"111","author":"K\u00e4smann-Kellner","year":"2014","journal-title":"Ophthalmologe"}],"container-title":["Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642019321013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642019321013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T12:34:10Z","timestamp":1777466050000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161642019321013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,2]]},"references-count":7,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2020,2]]}},"alternative-id":["S0161642019321013"],"URL":"https:\/\/doi.org\/10.1016\/j.ophtha.2019.09.034","relation":{},"ISSN":["0161-6420"],"issn-type":[{"value":"0161-6420","type":"print"}],"subject":[],"published":{"date-parts":[[2020,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"PAX6 Mutational Status Determines Aniridia-Associated Keratopathy Phenotype","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ophtha.2019.09.034","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 by the American Academy of OphthalmologyThis is an open access article under the CC BY-NC-ND license (<inter-ref xlink: href=http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/>http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/<\/inter-ref>).","name":"copyright","label":"Copyright"}]}}