{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T05:01:49Z","timestamp":1794373309269,"version":"4.9.0"},"reference-count":47,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,5,1]],"date-time":"2023-05-01T00:00:00Z","timestamp":1682899200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T00:00:00Z","timestamp":1713484800000},"content-version":"am","delay-in-days":354,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000064","name":"National Center for Complementary and Alternative Medicine","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000064","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HHS-N-260-2005-00007-C"],"award-info":[{"award-number":["HHS-N-260-2005-00007-C"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NOI-EY-0-2127"],"award-info":[{"award-number":["NOI-EY-0-2127"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZIAEY000546"],"award-info":[{"award-number":["ZIAEY000546"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000092","name":"U.S. National Library of Medicine","doi-asserted-by":"publisher","award":["K99 LM014024-01"],"award-info":[{"award-number":["K99 LM014024-01"]}],"id":[{"id":"10.13039\/100000092","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001818","name":"Research to Prevent Blindness","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001818","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004425","name":"Asian Development Bank","doi-asserted-by":"publisher","award":["N01-EY-5-0007"],"award-info":[{"award-number":["N01-EY-5-0007"]}],"id":[{"id":"10.13039\/100004425","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000063","name":"Office of Dietary Supplements","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000063","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000053","name":"National Eye Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000053","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aaojournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology"],"published-print":{"date-parts":[[2023,5]]},"DOI":"10.1016\/j.ophtha.2022.11.026","type":"journal-article","created":{"date-parts":[[2022,12,6]],"date-time":"2022-12-06T02:25:29Z","timestamp":1670293529000},"page":"488-500","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"title":["Reticular Pseudodrusen Status, ARMS2\/HTRA1 Genotype, and Geographic Atrophy Enlargement"],"prefix":"10.1016","volume":"130","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2829-4042","authenticated-orcid":false,"given":"Elvira","family":"Agr\u00f3n","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8145-9619","authenticated-orcid":false,"given":"Amitha","family":"Domalpally","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine A.","family":"Cukras","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Traci E.","family":"Clemons","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anand","family":"Swaroop","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0999-9802","authenticated-orcid":false,"given":"Emily Y.","family":"Chew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2253-1772","authenticated-orcid":false,"given":"Tiarnan D.L.","family":"Keenan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.ophtha.2022.11.026_bib1","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.ophtha.2011.09.027","article-title":"Age and gender variations in age-related macular degeneration prevalence in populations of European ancestry: a meta-analysis","volume":"119","author":"Rudnicka","year":"2012","journal-title":"Ophthalmology"},{"issue":"12","key":"10.1016\/j.ophtha.2022.11.026_bib2","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1016\/j.ophtha.2018.05.028","article-title":"Progression of geographic atrophy in age-related macular degeneration: AREDS2 report number 16","volume":"125","author":"Keenan","year":"2018","journal-title":"Ophthalmology"},{"issue":"3","key":"10.1016\/j.ophtha.2022.11.026_bib3","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.ophtha.2017.08.038","article-title":"The progression of geographic atrophy secondary to age-related macular degeneration","volume":"125","author":"Fleckenstein","year":"2018","journal-title":"Ophthalmology"},{"issue":"9","key":"10.1016\/j.ophtha.2022.11.026_bib4","doi-asserted-by":"crossref","first-page":"3456","DOI":"10.1167\/iovs.17-22339","article-title":"Report from the NEI\/FDA Endpoints Workshop on Age-Related Macular Degeneration and Inherited Retinal Diseases","volume":"58","author":"Csaky","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"8","key":"10.1016\/j.ophtha.2022.11.026_bib5","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1001\/jamaophthalmol.2019.1318","article-title":"Assessment of novel genome-wide significant gene loci and lesion growth in geographic atrophy secondary to age-related macular degeneration","volume":"137","author":"Grassmann","year":"2019","journal-title":"JAMA Ophthalmol"},{"issue":"6","key":"10.1016\/j.ophtha.2022.11.026_bib6","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.survophthal.2018.05.005","article-title":"Subretinal drusenoid deposits AKA pseudodrusen","volume":"63","author":"Spaide","year":"2018","journal-title":"Surv Ophthalmol"},{"issue":"10","key":"10.1016\/j.ophtha.2022.11.026_bib7","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1016\/j.ophtha.2022.05.021","article-title":"Reticular pseudodrusen: the third macular risk feature for progression to late age-related macular degeneration","volume":"29","author":"Agron","year":"2022","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2022.11.026_bib8","article-title":"Reticular pseudodrusen: a critical phenotype in age-related macular degeneration: Age-Related Eye Disease Study 2 Report 30","author":"Wu","year":"2021","journal-title":"Prog Retin Eye Res"},{"issue":"12","key":"10.1016\/j.ophtha.2022.11.026_bib9","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.ophtha.2019.07.022","article-title":"Prevalence, risk, and genetic association of reticular pseudodrusen in age-related macular degeneration: Age-Related Eye Disease Study 2 report 21","volume":"126","author":"Domalpally","year":"2019","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2022.11.026_bib10","doi-asserted-by":"crossref","unstructured":"Keenan TD, Agron E, Chew EY, AREDS2 Research Group. Reply. Ophthalmology. 2019;126(5):e40\u2013e41.","DOI":"10.1016\/j.ophtha.2018.11.030"},{"issue":"4","key":"10.1016\/j.ophtha.2022.11.026_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.xops.2021.100057","article-title":"Local Complement Inhibition for Geographic Atrophy in Age-Related Macular Degeneration: Prospects, Challenges, and Unanswered Questions","volume":"17","author":"Keenan","year":"2021","journal-title":"Ophthalmol Sci"},{"key":"10.1016\/j.ophtha.2022.11.026_bib12","series-title":"Introduction to Statistical Mediation Analysis","author":"MacKinnon","year":"2012"},{"issue":"1","key":"10.1016\/j.ophtha.2022.11.026_bib13","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1177\/1088868314542878","article-title":"Statistical approaches for enhancing causal interpretation of the M to Y relation in mediation analysis","volume":"19","author":"MacKinnon","year":"2015","journal-title":"Pers Soc Psychol Rev"},{"issue":"12","key":"10.1016\/j.ophtha.2022.11.026_bib14","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.oret.2020.04.014","article-title":"Genotype- and phenotype-based subgroups in geographic atrophy secondary to age-related macular degeneration: the EYE-RISK Consortium","volume":"4","author":"Biarnes","year":"2020","journal-title":"Ophthalmol Retina"},{"issue":"11","key":"10.1016\/j.ophtha.2022.11.026_bib15","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.oret.2021.07.006","article-title":"Cluster analysis and genotype-phenotype assessment of geographic atrophy in age-related macular degeneration: Age-Related Eye Disease Study 2 report 25","volume":"5","author":"Keenan","year":"2021","journal-title":"Ophthalmol Retina"},{"issue":"11","key":"10.1016\/j.ophtha.2022.11.026_bib16","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1016\/j.ophtha.2012.05.027","article-title":"The Age-Related Eye Disease Study 2 (AREDS2): study design and baseline characteristics (AREDS2 report number 1)","volume":"119","author":"Chew","year":"2012","journal-title":"Ophthalmology"},{"issue":"8","key":"10.1016\/j.ophtha.2022.11.026_bib17","first-page":"1761","article-title":"Measuring geographic atrophy in advanced age-related macular degeneration","volume":"40","author":"Sunness","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7","key":"10.1016\/j.ophtha.2022.11.026_bib18","doi-asserted-by":"crossref","first-page":"4548","DOI":"10.1167\/iovs.13-11804","article-title":"Methods and reproducibility of grading optimized digital color fundus photographs in the Age-Related Eye Disease Study 2 (AREDS2 report number 2)","volume":"54","author":"Danis","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"10.1016\/j.ophtha.2022.11.026_bib19","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1038\/ng.3448","article-title":"A\u00a0large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants","volume":"48","author":"Fritsche","year":"2016","journal-title":"Nat Genet"},{"issue":"9","key":"10.1016\/j.ophtha.2022.11.026_bib20","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.oret.2022.03.022","article-title":"Adherence to a Mediterranean diet and geographic atrophy enlargement rate: Age-Related Eye Disease Study 2 report 29","volume":"6","author":"Agron","year":"2022","journal-title":"Ophthalmol Retina"},{"issue":"1","key":"10.1016\/j.ophtha.2022.11.026_bib21","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1001\/jamaophthalmol.2013.572","article-title":"Square root transformation of geographic atrophy area measurements to eliminate dependence of growth rates on baseline lesion measurements: a reanalysis of Age-Related Eye Disease Study report no. 26","volume":"131","author":"Feuer","year":"2013","journal-title":"JAMA Ophthalmol"},{"issue":"11","key":"10.1016\/j.ophtha.2022.11.026_bib22","doi-asserted-by":"crossref","first-page":"3105","DOI":"10.1080\/03610929408831436","article-title":"General class of covariance structures for two or more repeated factors in longitudinal data analysis","volume":"23","author":"Galecki","year":"1994","journal-title":"Commun Stat Theory Methods"},{"issue":"2","key":"10.1016\/j.ophtha.2022.11.026_bib23","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1037\/a0031034","article-title":"Mediation analysis allowing for exposure-mediator interactions and causal interpretation: theoretical assumptions and implementation with SAS and SPSS macros","volume":"18","author":"Valeri","year":"2013","journal-title":"Psychol Methods"},{"issue":"408","key":"10.1016\/j.ophtha.2022.11.026_bib24","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1080\/01621459.1989.10478873","article-title":"Regression-analysis of multivariate incomplete failure time data by modeling marginal distributions","volume":"84","author":"Wei","year":"1989","journal-title":"J\u00a0Am Stat Assoc"},{"issue":"6","key":"10.1016\/j.ophtha.2022.11.026_bib25","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1093\/jamia\/ocaa302","article-title":"Multimodal, multitask, multiattention (M3) deep learning detection of reticular pseudodrusen: toward automated and accessible classification of age-related macular degeneration","volume":"28","author":"Chen","year":"2021","journal-title":"J\u00a0Am Med Inform Assoc"},{"issue":"12","key":"10.1016\/j.ophtha.2022.11.026_bib26","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1016\/j.ophtha.2020.05.036","article-title":"Deep learning automated detection of reticular pseudodrusen from fundus autofluorescence images or color fundus photographs in AREDS2","volume":"127","author":"Keenan","year":"2020","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2022.11.026_bib27","unstructured":"Schwartz R, Khalid H, Liakopoulos S, et al. A deep learning framework for the detection and quantification of drusen and reticular pseudodrusen on optical coherence tomography. 2022. Available at: https:\/\/pubmed.ncbi.nlm.nih.gov\/36458946\/. Accessed November 5, 2022."},{"issue":"12","key":"10.1016\/j.ophtha.2022.11.026_bib28","doi-asserted-by":"crossref","first-page":"1125","DOI":"10.1016\/j.oret.2020.08.009","article-title":"The hitchhiker\u2019s guide to cluster analysis: multi pertransibunt et augebitur scientia","volume":"4","author":"Keenan","year":"2020","journal-title":"Ophthalmol Retina"},{"issue":"9","key":"10.1016\/j.ophtha.2022.11.026_bib29","doi-asserted-by":"crossref","first-page":"1850","DOI":"10.1097\/IAE.0b013e31828991b2","article-title":"Reticular macular disease is associated with multilobular geographic atrophy in age-related macular degeneration","volume":"33","author":"Xu","year":"2013","journal-title":"Retina"},{"issue":"12","key":"10.1016\/j.ophtha.2022.11.026_bib30","doi-asserted-by":"crossref","first-page":"7362","DOI":"10.1167\/iovs.12-11073","article-title":"Association between geographic atrophy progression and reticular pseudodrusen in eyes with dry age-related macular degeneration","volume":"54","author":"Marsiglia","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"10.1016\/j.ophtha.2022.11.026_bib31","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1097\/IAE.0b013e31827e25e0","article-title":"Subretinal drusenoid deposits in non-neovascular age-related macular degeneration: morphology, prevalence, topography, and biogenesis model","volume":"33","author":"Curcio","year":"2013","journal-title":"Retina"},{"issue":"10","key":"10.1016\/j.ophtha.2022.11.026_bib32","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1016\/j.ophtha.2015.06.023","article-title":"Impairments in dark adaptation are associated with age-related macular degeneration severity and reticular pseudodrusen","volume":"122","author":"Flamendorf","year":"2015","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.ophtha.2022.11.026_bib33","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1167\/iovs.61.6.59","article-title":"Macular thickness in intermediate age-related macular degeneration is influenced by disease severity and subretinal drusenoid deposit presence","volume":"61","author":"Chiang","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"10.1016\/j.ophtha.2022.11.026_bib34","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1097\/IAE.0b013e31829c3765","article-title":"Outer retinal atrophy after regression of subretinal\u00a0drusenoid deposits as a newly recognized form of late age-related macular degeneration","volume":"33","author":"Spaide","year":"2013","journal-title":"Retina"},{"issue":"4","key":"10.1016\/j.ophtha.2022.11.026_bib35","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.ophtha.2017.09.028","article-title":"Consensus definition for atrophy associated with age-related macular degeneration on OCT: Classification of Atrophy report 3","volume":"125","author":"Sadda","year":"2018","journal-title":"Ophthalmology"},{"issue":"6","key":"10.1016\/j.ophtha.2022.11.026_bib36","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1016\/j.ophtha.2016.02.009","article-title":"Correlation of histologic features with in\u00a0vivo imaging of reticular pseudodrusen","volume":"123","author":"Greferath","year":"2016","journal-title":"Ophthalmology"},{"issue":"1","key":"10.1016\/j.ophtha.2022.11.026_bib37","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1167\/iovs.62.1.33","article-title":"Biometrics, impact, and significance of basal linear deposit and subretinal drusenoid deposit in age-related macular degeneration","volume":"62","author":"Chen","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.ophtha.2022.11.026_bib38","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/978-3-030-66014-7_5","article-title":"Innate immunity in age-related macular degeneration","volume":"1256","author":"Zhang","year":"2021","journal-title":"Adv Exp Med Biol"},{"issue":"4","key":"10.1016\/j.ophtha.2022.11.026_bib39","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1097\/IAE.0000000000002434","article-title":"Choroidal thickness and vascularity vary with disease severity and subretinal drusenoid deposit presence in nonadvanced age-related macular degeneration","volume":"40","author":"Keenan","year":"2020","journal-title":"Retina"},{"issue":"8","key":"10.1016\/j.ophtha.2022.11.026_bib40","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.molmed.2016.06.009","article-title":"A\u00a0revised hemodynamic theory of age-related macular degeneration","volume":"22","author":"Gelfand","year":"2016","journal-title":"Trends Mol Med"},{"issue":"6","key":"10.1016\/j.ophtha.2022.11.026_bib41","doi-asserted-by":"crossref","first-page":"4054","DOI":"10.1167\/iovs.12-11538","article-title":"Longitudinal analysis of reticular drusen associated with geographic atrophy in age-related macular degeneration","volume":"54","author":"Steinberg","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"10.1016\/j.ophtha.2022.11.026_bib42","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1038\/s41433-021-01747-z","article-title":"Fundus autofluorescence and optical coherence tomography biomarkers associated with the progression of geographic atrophy secondary to age-related macular degeneration","volume":"36","author":"Bui","year":"2022","journal-title":"Eye (Lond)"},{"issue":"6","key":"10.1016\/j.ophtha.2022.11.026_bib43","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1167\/iovs.61.6.11","article-title":"Subretinal drusenoid deposits and photoreceptor loss detecting global and local progression of geographic atrophy by SD-OCT imaging","volume":"61","author":"Reiter","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"10.1016\/j.ophtha.2022.11.026_bib44","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1136\/bjophthalmol-2020-316004","article-title":"Prognostic value of intermediate age-related macular degeneration phenotypes for geographic atrophy progression","volume":"105","author":"Thiele","year":"2021","journal-title":"Br J Ophthalmol"},{"issue":"11","key":"10.1016\/j.ophtha.2022.11.026_bib45","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1016\/j.ophtha.2016.06.025","article-title":"Evaluation of geographic atrophy from color photographs and fundus autofluorescence images: Age-Related Eye Disease Study 2 report number 11","volume":"123","author":"Domalpally","year":"2016","journal-title":"Ophthalmology"},{"issue":"395","key":"10.1016\/j.ophtha.2022.11.026_bib46","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aaf1443","article-title":"Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration","volume":"9","author":"Yaspan","year":"2017","journal-title":"Sci Transl Med"},{"issue":"9","key":"10.1016\/j.ophtha.2022.11.026_bib47","doi-asserted-by":"crossref","first-page":"1884","DOI":"10.1097\/IAE.0b013e3182509778","article-title":"Comparison of color fundus photographs and fundus autofluorescence images in measuring geographic atrophy area","volume":"32","author":"Khanifar","year":"2012","journal-title":"Retina"}],"container-title":["Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642022009320?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642022009320?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T14:13:01Z","timestamp":1758982381000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161642022009320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,5]]},"references-count":47,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2023,5]]}},"alternative-id":["S0161642022009320"],"URL":"https:\/\/doi.org\/10.1016\/j.ophtha.2022.11.026","relation":{},"ISSN":["0161-6420"],"issn-type":[{"value":"0161-6420","type":"print"}],"subject":[],"published":{"date-parts":[[2023,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Reticular Pseudodrusen Status, ARMS2\/HTRA1 Genotype, and Geographic Atrophy Enlargement","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ophtha.2022.11.026","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier on behalf of the American Academy of Ophthalmology","name":"copyright","label":"Copyright"}]}}