{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T21:08:11Z","timestamp":1789160891892,"version":"build-2803163510"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100001758","name":"Lions Gift of Sight","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001758","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005800","name":"Eye Bank Association of America Inc","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100005800","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016850","name":"Beauty of Sight Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016850","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100018313","name":"Cleveland Eye Bank Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100018313","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007048","name":"Mayo Clinic","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007048","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["aaojournal.org","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.ophtha.2026.07.022","type":"journal-article","created":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T23:24:50Z","timestamp":1785281090000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Factors Associated with Successful Descemet Membrane Endothelial Keratoplasty in the Diabetes Endothelial Keratoplasty Study"],"prefix":"10.1016","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6652-534X","authenticated-orcid":false,"given":"Marianne O.","family":"Price","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Loretta B.","family":"Szczotka-Flynn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachariah W.","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin L.","family":"Gal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5849-5830","authenticated-orcid":false,"given":"Ari M.","family":"Brandsdorfer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Greenwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark A.","family":"Greiner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ula V.","family":"Jurkunas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen H.","family":"Koo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parag A.","family":"Majmudar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Francis W.","family":"Price","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Divya","family":"Srikumaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter B.","family":"Veldman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David D.","family":"Verdier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roy W.","family":"Beck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan H.","family":"Lass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay V.","family":"Patel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith H.","family":"Baratz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahzad","family":"Mian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Hood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nambi","family":"Nallasamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Verkade","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence","family":"Tenkman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjulie","family":"Gang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Ketcherside","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesse","family":"Vislisel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evan","family":"Schoenberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Huffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yassine","family":"Daoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen","family":"Eghrari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Jun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Boyce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Kam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Terry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Straiko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Croasdale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel","family":"Epstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neal","family":"Vaidya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandini","family":"Venkateswaran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon","family":"Ayres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Hansen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Hardten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sherman","family":"Reeves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Bowes","family":"Hamill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Omar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"Potts","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Bokosky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sudeep","family":"Pramanik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ophtha.2026.07.022_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.preteyeres.2020.100904","article-title":"Corneal endothelial dysfunction: evolving understanding and treatment options","volume":"82","author":"Price","year":"2021","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.ophtha.2026.07.022_bib3","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1097\/ICO.0000000000000045","article-title":"Descemet membrane endothelial keratoplasty donor preparation: navigating challenges and improving efficiency","volume":"33","author":"Tenkman","year":"2014","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib4","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.ophtha.2015.08.044","article-title":"The S-stamp in Descemet membrane endothelial keratoplasty safely eliminates upside-down graft implantation","volume":"123","author":"Veldman","year":"2016","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib5","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1097\/ICO.0000000000000479","article-title":"Standardized DMEK technique: reducing complications using prestripped tissue, novel glass injector, and sulfur hexafluoride (SF6) gas","volume":"34","author":"Terry","year":"2015","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib6","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1097\/ICO.0000000000003776","article-title":"Diabetes Endothelial Keratoplasty Study: Methods and impact on the use of corneas from donors with diabetes for Descemet membrane endothelial keratoplasty","volume":"45","author":"Price","year":"2026","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib7","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1001\/jamaophthalmol.2025.4261","article-title":"Endothelial cell loss 1 year after successful DMEK in the Diabetes Endothelial Keratoplasty Study: a randomized clinical trial","volume":"143","author":"Lass","year":"2025","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.ophtha.2026.07.022_bib8","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1001\/jamaophthalmol.2025.4253","article-title":"Effect of diabetes in the donor on Descemet membrane endothelial keratoplasty success: results of a randomized controlled trial","volume":"143","author":"Price","year":"2025","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.ophtha.2026.07.022_bib9","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1097\/ICO.0000000000001211","article-title":"Validity of postmortem glycated hemoglobin to determine status of diabetes mellitus in corneal donors","volume":"36","author":"Soper","year":"2017","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib11","series-title":"Cornea: Fundamentals, Diagnosis, Management","first-page":"130","article-title":"Specular microscopy","author":"Benetz","year":"2021"},{"key":"10.1016\/j.ophtha.2026.07.022_bib12","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1097\/ICO.0000000000000417","article-title":"Cornea Preservation Time Study: methods and potential impact on the cornea donor pool in the United States","volume":"34","author":"Lass","year":"2015","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib13","doi-asserted-by":"crossref","first-page":"e922","DOI":"10.1111\/aos.14708","article-title":"Causes of corneal transplant failure: a multicentric study","volume":"99","author":"G\u00f3mez-Benlloch","year":"2021","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.ophtha.2026.07.022_bib14","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/j.ophtha.2018.08.002","article-title":"Donor, recipient, and operative factors associated with graft success in the Cornea Preservation Time Study","volume":"125","author":"Terry","year":"2018","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib15","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/j.ophtha.2017.08.015","article-title":"Descemet membrane endothelial keratoplasty: safety and outcomes: a report by the American Academy of Ophthalmology","volume":"125","author":"Deng","year":"2018","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib16","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1016\/j.ophtha.2011.09.019","article-title":"Risk of corneal transplant rejection significantly reduced with Descemet's membrane endothelial keratoplasty","volume":"119","author":"Anshu","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.ophtha.2026.07.027","article-title":"Donor, recipient, and operative factors associated with increased endothelial cell loss in the Diabetes Endothelial Keratoplasty Study","author":"Patel","year":"2026","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib18","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1001\/archophthalmol.2010.128.63","article-title":"Endothelial cell density to predict endothelial graft failure after penetrating keratoplasty","volume":"128","author":"Lass","year":"2010","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.ophtha.2026.07.022_bib19","doi-asserted-by":"crossref","first-page":"1076","DOI":"10.1016\/j.ophtha.2019.02.011","article-title":"Postoperative endothelial cell density is associated with late endothelial graft failure after Descemet stripping automated endothelial keratoplasty","volume":"126","author":"Patel","year":"2019","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib20","author":"Lass"},{"key":"10.1016\/j.ophtha.2026.07.022_bib21","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1097\/ICO.0000000000001305","article-title":"Effect of donor and recipient diabetes status on Descemet membrane endothelial keratoplasty adherence and survival","volume":"36","author":"Price","year":"2017","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib22","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.ophtha.2008.12.050","article-title":"Recipient risk factors for graft failure in the cornea donor study","volume":"116","author":"Sugar","year":"2009","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib23","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1097\/ICO.0000000000003130","article-title":"Long-term outcomes of Descemet membrane endothelial keratoplasty: effect of surgical indication and disease severity","volume":"42","author":"Vasiliauskaite","year":"2023","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib24","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1016\/j.ophtha.2012.04.031","article-title":"Descemet's stripping endothelial keratoplasty: long-term graft survival and risk factors for failure in eyes with preexisting glaucoma","volume":"119","author":"Anshu","year":"2012","journal-title":"Ophthalmology"},{"key":"10.1016\/j.ophtha.2026.07.022_bib25","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.ajo.2020.05.020","article-title":"Four-year survival of Descemet membrane endothelial keratoplasty in patients with previous glaucoma surgery","volume":"218","author":"Sorkin","year":"2020","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2026.07.022_bib26","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.ajo.2018.11.014","article-title":"Clinical outcomes of Descemet membrane endothelial keratoplasty in eyes with a glaucoma drainage device","volume":"199","author":"Birbal","year":"2019","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.ophtha.2026.07.022_bib27","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/ICO.0000000000001763","article-title":"Descemet membrane endothelial keratoplasty for failed penetrating keratoplasty: visual outcomes and graft survival","volume":"38","author":"Pasari","year":"2019","journal-title":"Cornea"},{"key":"10.1016\/j.ophtha.2026.07.022_bib28","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.survophthal.2017.11.002","article-title":"Glaucoma-associated corneal endothelial cell damage: a review","volume":"63","author":"Janson","year":"2018","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.ophtha.2026.07.022_bib29","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1001\/jamaophthalmol.2018.5669","article-title":"Donor, recipient, and operative factors associated with increased endothelial cell loss in the Cornea Preservation Time Study","volume":"137","author":"Lass","year":"2019","journal-title":"JAMA Ophthalmol"}],"container-title":["Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642026005269?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0161642026005269?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T20:40:13Z","timestamp":1789159213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0161642026005269"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":27,"alternative-id":["S0161642026005269"],"URL":"https:\/\/doi.org\/10.1016\/j.ophtha.2026.07.022","relation":{},"ISSN":["0161-6420"],"issn-type":[{"value":"0161-6420","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Factors Associated with Successful Descemet Membrane Endothelial Keratoplasty in the Diabetes Endothelial Keratoplasty Study","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ophtha.2026.07.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 American Academy of Ophthalmology, Inc. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}