{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T08:03:27Z","timestamp":1781078607739,"version":"3.54.1"},"reference-count":8,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["clinicalkey.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Open Respiratory Archives"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.opresp.2026.100600","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T16:23:38Z","timestamp":1772036618000},"page":"100600","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["Nitrofurantoin-induced Toxicity. A Diagnostic Challenge"],"prefix":"10.1016","volume":"8","author":[{"given":"Patricia P.","family":"Huelamo-L\u00f3pez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raquel","family":"Garc\u00eda-Sevila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Gay\u00e1-Garc\u00eda-Manso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"D\u00edez-DeLe\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda J.","family":"Soler Sempere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.opresp.2026.100600_bib0045","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1093\/jac\/42.3.363","article-title":"Efficacy and safety profile of long-term nitrofurantoin in urinary infections: 18 years\u2019 experience","volume":"42","author":"Brumfitt","year":"1998","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.opresp.2026.100600_bib0050","first-page":"180","article-title":"Pulmonary reactions to nitrofurantoin. 447 cases reported to the Swedish Adverse Drug Reaction Committee 1966\u20131976","volume":"62","author":"Holmberg","year":"1981","journal-title":"Eur J Respir Dis"},{"key":"10.1016\/j.opresp.2026.100600_bib0055","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1378\/chest.96.3.512","article-title":"Hospitalizations for pulmonary reactions following nitrofurantoin use","volume":"96","author":"Jick","year":"1989","journal-title":"Chest"},{"key":"10.1016\/j.opresp.2026.100600_bib0060","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1186\/1752-1947-2-169","article-title":"Nitrofurantoin-induced pulmonary fibrosis: a case report","volume":"2","author":"Goemaere","year":"2008","journal-title":"J Med Case Rep"},{"key":"10.1016\/j.opresp.2026.100600_bib0065","doi-asserted-by":"crossref","first-page":"382","DOI":"10.3390\/toxics13050382","article-title":"Nitrofurantoin-induced pulmonary toxicity: mechanisms, diagnosis, and management","volume":"13","author":"Kaye","year":"2025","journal-title":"Toxics"},{"key":"10.1016\/j.opresp.2026.100600_bib0070","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.rce.2018.09.015","article-title":"Reversible pulmonary toxicity by nitrofurantoin","volume":"220","author":"Santos Seoane","year":"2020","journal-title":"Rev Clin Esp (Barc)"},{"key":"10.1016\/j.opresp.2026.100600_bib0075","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/j.chest.2021.06.057","article-title":"Presenting features and clinical course of chronic nitrofurantoin-induced lung toxicity","volume":"161","author":"Tzilas","year":"2022","journal-title":"Chest"},{"key":"10.1016\/j.opresp.2026.100600_bib0080","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1016\/S1579-2129(09)72437-1","article-title":"Nitrofuranto\u00edna y enfermedad pulmonar intersticial de r\u00e1pida resoluci\u00f3n","volume":"45","author":"Viejo","year":"2009","journal-title":"Arch Bronconeumol"}],"container-title":["Open Respiratory Archives"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2659663626000640?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2659663626000640?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T07:40:38Z","timestamp":1781077238000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2659663626000640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S2659663626000640"],"URL":"https:\/\/doi.org\/10.1016\/j.opresp.2026.100600","relation":{},"ISSN":["2659-6636"],"issn-type":[{"value":"2659-6636","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nitrofurantoin-induced Toxicity. A Diagnostic Challenge","name":"articletitle","label":"Article Title"},{"value":"Open Respiratory Archives","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.opresp.2026.100600","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"simple-article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Sociedad Espa\u00f1ola de Neumolog\u00eda y Cirug\u00eda Tor\u00e1cica (SEPAR). Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}],"article-number":"100600"}}