{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:20:25Z","timestamp":1761823225713,"version":"build-2065373602"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,5,5]],"date-time":"2017-05-05T00:00:00Z","timestamp":1493942400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"internal Nova Southeastern University, Health Profession Division","award":["035684"],"award-info":[{"award-number":["035684"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.es","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Optometry"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.optom.2017.02.004","type":"journal-article","created":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T09:00:16Z","timestamp":1498899616000},"page":"75-85","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["More sensitive correlation of afferent pupillary defect with ganglion cell complex"],"prefix":"10.1016","volume":"11","author":[{"given":"Eulogio","family":"Besada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry J.","family":"Frauens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rim","family":"Makhlouf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Shechtman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Rodman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marlon","family":"Demeritt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Hardigan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.optom.2017.02.004_bib0185","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1001\/archopht.1987.01060110086038","article-title":"The afferent pupillary defect in asymmetric glaucoma","volume":"105","author":"Brown","year":"1987","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0190","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1001\/archopht.1993.01090070056019","article-title":"Clinical grading of relative afferent papillary defects","volume":"111","author":"Bell","year":"1993","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0195","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1136\/bjo.2006.105494","article-title":"Quantification of retinal nerve fiber layer thickness reduction associated with a relative afferent pupillary defect in asymmetric glaucoma","volume":"91","author":"Tatsumi","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0200","first-page":"4013","article-title":"Correlation of relative afferent pupillary defect and retinal nerve fiber layer loss in unilateral or asymmetric demyelinating optic neuropathy","volume":"51","author":"Younis","year":"2010","journal-title":"Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0205","doi-asserted-by":"crossref","first-page":"5049","DOI":"10.1167\/iovs.09-4216","article-title":"Retinal nerve fiber layer loss in glaucoma patients with a relative afferent pupillary defect","volume":"51","author":"Chew","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0210","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1212\/WNL.0b013e3181f735bd","article-title":"Association between retinal fiber layer abnormalities and optic nerve examination","volume":"75","author":"Cettomai","year":"2010","journal-title":"Neurology"},{"key":"10.1016\/j.optom.2017.02.004_bib0215","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1007\/s00417-006-0327-1","article-title":"Quantification of retinal nerve fiber layerthickness reduction associated with a relative afferent pupillary defect","volume":"244","author":"Nakanishi","year":"2006","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0220","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1167\/iovs.13-12921","article-title":"Estimation of retinal ganglion cell loss in glaucomatous eyes with a relative afferent pupillary defect","volume":"55","author":"Tatham","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0225","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1001\/archopht.119.9.1333","article-title":"Quantification of optic nerve axon loss associated with a relative afferent pupillary defect in the monkey","volume":"119","author":"Kerrison","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0230","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1167\/iovs.10-5546","article-title":"Effect of disease severity and optic disc size on diagnostic accuracy of RTVue spectral domain optical coherence tomograph in glaucoma","volume":"52","author":"Rao","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0235","series-title":"RTVue Fourier-Domain Optical Coherence Tomography Primer Series: Volume III Glaucoma","first-page":"3","article-title":"Introduction to RTVue for glaucoma diagnosis","author":"Huang","year":"2009"},{"key":"10.1016\/j.optom.2017.02.004_bib0240","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/IJG.0b013e31826a9707","article-title":"Detection of early glaucomatous progression with different parameters of the RTVue optical coherence tomograph","volume":"23","author":"Naghizadeh","year":"2014","journal-title":"J Glaucoma"},{"key":"10.1016\/j.optom.2017.02.004_bib0245","doi-asserted-by":"crossref","first-page":"8900","DOI":"10.1167\/iovs.11-7644","article-title":"Functional loss in the magnocellular and parvocellular pathways in patients with optic neuritis","volume":"52","author":"Cao","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0250","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0002-9394(14)78297-2","article-title":"A clinicopathologic study of optic neuropathies associated with intracranial mass lesions with quantification of remaining axons","volume":"95","author":"Levin","year":"1983","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0255","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1007\/s004170050096","article-title":"Correlation of relative afferent pupillary defect and estimated retinal ganglion cell loss","volume":"236","author":"Lagreze","year":"1998","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0260","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0002-9394(14)73587-1","article-title":"The relationship between static perimetry and the relative afferent pupillary defect","volume":"115","author":"Kardon","year":"1993","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0265","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0002-9394(14)76939-9","article-title":"The use of crossed polarized filters in the measurement of the relative afferent pupillary defect","volume":"110","author":"Rosenberg","year":"1990","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0270","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1136\/bjo.86.9.985","article-title":"Quantifying relative afferent pupillary defects using a Sbisa bar","volume":"86","author":"McCormick","year":"2002","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0275","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1167\/iovs.13-13052","article-title":"Relationship between visual acuity and retinal structures measured by spectral domain optical coherence tomography in patients with open-angle glaucoma","volume":"55","author":"Kim","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0280","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1097\/IJG.0b013e3181e079cd","article-title":"Temporal retinal thickness in eyes with glaucomatous visual field defects using optical coherence tomography","volume":"24","author":"Sihota","year":"2015","journal-title":"J Glaucoma"},{"key":"10.1016\/j.optom.2017.02.004_bib0285","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0161-6420(02)01564-6","article-title":"Optical coherence tomography measurement of macular and nerve fiber layer thickness in normal and glaucomatous human eyes","volume":"110","author":"Guedes","year":"2003","journal-title":"Ophthalmology"},{"key":"10.1016\/j.optom.2017.02.004_bib0290","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.exer.2012.12.010","article-title":"Number and spatial distribution of intrinsically photosensitive retinal ganglion cells in the adult albino rat","volume":"108","author":"Galindo-Romero","year":"2013","journal-title":"Exp Eye Res"},{"key":"10.1016\/j.optom.2017.02.004_bib0295","doi-asserted-by":"crossref","first-page":"7997","DOI":"10.1167\/iovs.14-15146","article-title":"A positive association between intrinsically photosensitive retinal ganglion cells and retinal nerve fiber layer thinning in glaucoma","volume":"55","author":"Gracitelli","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0300","first-page":"200","article-title":"The usefulness of a new method of testing for a relative afferent pupillary defect in patients with ocular hypertension and glaucoma","volume":"103","author":"Lankaranian","year":"2005","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.optom.2017.02.004_bib0305","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1001\/archopht.1990.01070060025009","article-title":"Quantitative pupillometry of relative afferent defects in glaucoma","volume":"108","author":"Jonas","year":"1990","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0310","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.preteyeres.2010.02.001","article-title":"Linking structure and function in glaucoma","volume":"29","author":"Harwerth","year":"2010","journal-title":"Prog Retin Eye Res"},{"key":"10.1016\/j.optom.2017.02.004_bib0315","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1001\/archophthalmol.2012.827","article-title":"A combined index of structure and function for staging glaucomatous damage","volume":"130","author":"Medeiros","year":"2012","journal-title":"Arch Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0320","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1016\/j.ajo.2012.04.022","article-title":"Estimating the rate of retinal ganglion cell loss in glaucoma","volume":"154","author":"Medeiros","year":"2012","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.optom.2017.02.004_bib0325","doi-asserted-by":"crossref","first-page":"6939","DOI":"10.1167\/iovs.12-10345","article-title":"The structure and function relationship in glaucoma: implications for detection of progression and measurement of rates of change","volume":"53","author":"Medeiros","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0330","doi-asserted-by":"crossref","first-page":"5596","DOI":"10.1167\/iovs.13-12142","article-title":"Symmetry of the pupillary light reflex and its relationship to retinal nerve fiber layer thickness and visual field defect","volume":"54","author":"Chang","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0335","doi-asserted-by":"crossref","first-page":"6208","DOI":"10.1167\/iovs.15-17259","article-title":"Details of glaucomatous damage are better seen on OCT en face images than on OCT retinal nerve fiber layer thickness maps","volume":"56","author":"Hood","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1016\/j.optom.2017.02.004_bib0340","first-page":"254","article-title":"Spectral domain optical coherence tomography in glaucoma: qualitative and quantitative analysis of the optic nerve head and retinal nerve fiber layer (an AOS thesis)","volume":"107","author":"Chen","year":"2009","journal-title":"Trans Am Ophthalmol Soc"},{"key":"10.1016\/j.optom.2017.02.004_bib0345","doi-asserted-by":"crossref","first-page":"2337","DOI":"10.1016\/j.ophtha.2010.04.002","article-title":"Retinal nerve fiber layer imaging with spectral-domain optical coherence tomography: pattern of RNFL defects in glaucoma","volume":"117","author":"Leung","year":"2010","journal-title":"Ophthalmology"},{"key":"10.1016\/j.optom.2017.02.004_bib0350","article-title":"Optical coherence tomography in multiple sclerosis and neuromyelitis optica: an update","volume":"2011","author":"Noval","year":"2011","journal-title":"Mult Scler Int"},{"key":"10.1016\/j.optom.2017.02.004_bib0355","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1097\/IJG.0000000000000129","article-title":"Microcystic macular changes in primary open-angle glaucoma","volume":"25","author":"Wen","year":"2016","journal-title":"J Glaucoma"},{"key":"10.1016\/j.optom.2017.02.004_bib0360","doi-asserted-by":"crossref","first-page":"2133","DOI":"10.1097\/IAE.0b013e31828e68d0","article-title":"Retinal inner nuclear layer microcystic changes in optic nerve atrophy: a novel spectral-domain OCT finding","volume":"33","author":"Wolff","year":"2013","journal-title":"Retina"}],"container-title":["Journal of Optometry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1888429617300390?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1888429617300390?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:11:00Z","timestamp":1761822660000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1888429617300390"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018,4]]}},"alternative-id":["S1888429617300390"],"URL":"https:\/\/doi.org\/10.1016\/j.optom.2017.02.004","relation":{},"ISSN":["1888-4296"],"issn-type":[{"type":"print","value":"1888-4296"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"More sensitive correlation of afferent pupillary defect with ganglion cell complex","name":"articletitle","label":"Article Title"},{"value":"Journal of Optometry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.optom.2017.02.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Spanish General Council of Optometry. Published by Elsevier Espa\u00f1a, S.L.U.","name":"copyright","label":"Copyright"}]}}