{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T11:09:42Z","timestamp":1648811382471},"reference-count":33,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Obesity Research & Clinical Practice"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.orcp.2011.11.008","type":"journal-article","created":{"date-parts":[[2011,12,20]],"date-time":"2011-12-20T23:37:27Z","timestamp":1324424247000},"page":"e225-e232","source":"Crossref","is-referenced-by-count":1,"title":["Masked function of amino acid sensors on pancreatic hormone secretion in ventromedial hypothalamic (VMH) lesioned rats with marked hyperinsulinemia"],"prefix":"10.1016","volume":"6","author":[{"given":"Noriko","family":"Ishizuka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsuaki","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuri","family":"Kintaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ikiko","family":"Kinoshita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeo","family":"Hashiguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akira","family":"Senoo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuo","family":"Imazeki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Kobayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsumi","family":"Arai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryota","family":"Haba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tosei","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kahoru","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masako","family":"Kako","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaori","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshimasa","family":"Osaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuichi","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuji","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.orcp.2011.11.008_bib0005","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s001250051322","article-title":"Autonomic regulation of islet hormone secretion-implications for health and disease","volume":"43","author":"Ahren","year":"2000","journal-title":"Diabetologia"},{"key":"10.1016\/j.orcp.2011.11.008_bib0010","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1210\/edrv-2-4-471","article-title":"Pancreatic neuroendocrinology: peripheral neural mechanisms in the regulation of the islets of Langerhans","volume":"2","author":"Miller","year":"1981","journal-title":"Endocr Rev"},{"key":"10.1016\/j.orcp.2011.11.008_bib0015","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/197079b0","article-title":"A hypothesis on the participation of hepatic glucoreceptors in the control of food intake","volume":"197","author":"Russek","year":"1963","journal-title":"Nature"},{"key":"10.1016\/j.orcp.2011.11.008_bib0020","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1111\/j.1749-6632.1969.tb12914.x","article-title":"Afferent impulse discharges from glucoreceptors in the liver of the guinea pig","volume":"157","author":"Niijima","year":"1969","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.orcp.2011.11.008_bib0025","series-title":"Food intake and chemical senses","first-page":"413","article-title":"Nervous regulatory mechanism of blood glucose levels","author":"Niijima","year":"1977"},{"key":"10.1016\/j.orcp.2011.11.008_bib0030","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1210\/endo-117-1-307","article-title":"The hepatic vagus nerve and the neural regulation of insulin secretion","volume":"117","author":"Lee","year":"1985","journal-title":"Endocrinology"},{"key":"10.1016\/j.orcp.2011.11.008_bib0035","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0031-9384(93)90022-8","article-title":"Hepatic glucose-sensitive unit regulation of glucose-induced insulin secretion in rats","volume":"53","author":"Nagase","year":"1993","journal-title":"Physiol Behav"},{"key":"10.1016\/j.orcp.2011.11.008_bib0040","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/0304-3940(86)90621-X","article-title":"Enhancement of insulin and glucagon secretion by arginine after hepatic vagotomy","volume":"72","author":"Tanaka","year":"1986","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.orcp.2011.11.008_bib0045","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0304-3940(86)90620-8","article-title":"Arginine sensors in the hepato-portal system and their reflex effects on pancreatic efferents in the rat","volume":"72","author":"Tanaka","year":"1986","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.orcp.2011.11.008_bib0050","doi-asserted-by":"crossref","first-page":"2017","DOI":"10.1210\/endo-127-4-2017","article-title":"Modulation of arginine-induced insulin and glucagon secretion by the hepatic vagus nerve in the rat: effects of celiac vagotomy and administration of atropine","volume":"127","author":"Tanaka","year":"1990","journal-title":"Endocrinology"},{"key":"10.1016\/j.orcp.2011.11.008_bib0055","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0165-1838(90)90170-N","article-title":"Amino acid sensors sensitive to alanine and leucine exist in the hepato-portal system in the rat","volume":"31","author":"Tanaka","year":"1990","journal-title":"J Auton Nerv Syst"},{"key":"10.1016\/j.orcp.2011.11.008_bib0060","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0165-1838(93)90367-4","article-title":"Hepatic vagal amino acid sensors modulate amino acid induced insulin and glucagon secretion in the rat","volume":"42","author":"Tanaka","year":"1993","journal-title":"J Auton Nerv Syst"},{"key":"10.1016\/j.orcp.2011.11.008_bib0065","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1152\/ajplegacy.1976.231.4.1043","article-title":"An hepatic osmoreceptor mechanism in the electrophysiological and behavioral studies","volume":"231","author":"Adachi","year":"1976","journal-title":"Am J Physiol"},{"key":"10.1016\/j.orcp.2011.11.008_bib0070","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0165-1838(83)90108-X","article-title":"The afferent and preganglionic parasympathetic innervation of the rat demonstrated by the retrograde transport of horseradish peroxidase","volume":"8","author":"Magni","year":"1983","journal-title":"J Auton Nerv Syst"},{"key":"10.1016\/j.orcp.2011.11.008_bib0075","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1210\/endo-100-1-108","article-title":"The effects of subdiaphragmatic vagotomy in rat with ventromedial hypothalamic obesity","volume":"100","author":"Inoue","year":"1977","journal-title":"Endocrinology"},{"key":"10.1016\/j.orcp.2011.11.008_bib0080","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1038\/266742a0","article-title":"Effect of transplantation of pancreas on development of hypothalamic obesity","volume":"226","author":"Inoue","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.orcp.2011.11.008_bib0085","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0006-8993(84)90222-1","article-title":"Effects of hypothalamic lesion on pancreatic autonomic nerve activity in the rat","volume":"303","author":"Yoshimatsu","year":"1984","journal-title":"Brain Res"},{"key":"10.1016\/j.orcp.2011.11.008_bib0090","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1038\/274900a0","article-title":"Ventromedial hypothalamus modulates fat mobilisation during fasting","volume":"274","author":"Bray","year":"1978","journal-title":"Nature"},{"key":"10.1016\/j.orcp.2011.11.008_bib0095","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/0024-3205(79)90549-6","article-title":"An autonomic hypothesis for hypothalamic obesity","volume":"25","author":"Inoue","year":"1979","journal-title":"Life Sci"},{"key":"10.1016\/j.orcp.2011.11.008_bib0100","first-page":"372","article-title":"Hyperinsulinemia in rats with hypothalamic obesity: effects of autonomic drugs and glucose","volume":"245","author":"Inoue","year":"1983","journal-title":"Am J Physiol"},{"key":"10.1016\/j.orcp.2011.11.008_bib0105","first-page":"162","article-title":"Comparison of metabolic alterations in hypothalamic and high fat diet induced obesity","volume":"233","author":"Inoue","year":"1977","journal-title":"Am J Physiol"},{"key":"10.1016\/j.orcp.2011.11.008_bib0110","series-title":"The rat forebrain in stereotaxic coordinates","author":"De Groot","year":"1959"},{"key":"10.1016\/j.orcp.2011.11.008_bib0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2337\/diabetes.26.1.1","article-title":"A method for studying acute insulin secretion and glucose tolerance in unanesthetized and unrestrained rats","volume":"26","author":"Shah","year":"1977","journal-title":"Diabetes"},{"key":"10.1016\/j.orcp.2011.11.008_bib0120","first-page":"331","article-title":"A method for large volume blood sampling and transfusion in rats","volume":"250","author":"Berthoud","year":"1986","journal-title":"Am J Physiol"},{"key":"10.1016\/j.orcp.2011.11.008_bib0125","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1677\/JOE-08-0290","article-title":"Physiology of the pancreatic alpha-cell and glucagon secretion: role in glucose homeostasis and diabetes","volume":"199","author":"Quesada","year":"2008","journal-title":"J Endocrinol"},{"key":"10.1016\/j.orcp.2011.11.008_bib0130","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1172\/JCI105456","article-title":"Stimulation of insulin secretion by amino acids","volume":"45","author":"Floyds","year":"1966","journal-title":"J Clin Invest"},{"key":"10.1016\/j.orcp.2011.11.008_bib0135","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1152\/physrev.1979.59.3.719","article-title":"Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis","volume":"59","author":"Bray","year":"1979","journal-title":"Physiol Rev"},{"key":"10.1016\/j.orcp.2011.11.008_bib0140","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.physbeh.2005.10.007","article-title":"The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight","volume":"87","author":"King","year":"2006","journal-title":"Physiol Behav"},{"key":"10.1016\/j.orcp.2011.11.008_bib0145","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/0361-9230(91)90151-9","article-title":"Role of the efferent and afferent vagus nerve in the development of ventromedial hypothalamic (VMH) obesity","volume":"27","author":"Inoue","year":"1991","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.orcp.2011.11.008_bib0150","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1371\/journal.pbio.0050143","article-title":"AKATP channel-dependent pathway within \u03b1 cells regulates glucagon release from both rodent and human islets of Langerhans","volume":"5","author":"MacDonald","year":"2007","journal-title":"PLoS Biol"},{"key":"10.1016\/j.orcp.2011.11.008_bib0155","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1152\/ajpendo.90295.2008","article-title":"Insulin as a physiological modulator of glucagon secretion","volume":"295","author":"Bansal","year":"2008","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.orcp.2011.11.008_bib0160","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1210\/er.2006-0007","article-title":"\u03b1-Cells of the endocrine pancreas: 35 years of research but the enigma remains","volume":"28","author":"Gromada","year":"2007","journal-title":"Endocr Rev"},{"key":"10.1016\/j.orcp.2011.11.008_bib0165","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/0031-9384(93)90147-8","article-title":"Modulation of insulin secretion by hepatic vagotomy in cirrhotic rats","volume":"53","author":"Okazaki","year":"1993","journal-title":"Physiol Behav"}],"container-title":["Obesity Research & Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871403X11002262?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1871403X11002262?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,21]],"date-time":"2019-06-21T00:17:55Z","timestamp":1561076275000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1871403X11002262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":33,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S1871403X11002262"],"URL":"https:\/\/doi.org\/10.1016\/j.orcp.2011.11.008","relation":{},"ISSN":["1871-403X"],"issn-type":[{"value":"1871-403X","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}