{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T15:27:11Z","timestamp":1784993231172,"version":"3.55.0"},"reference-count":39,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004853","name":"Chinese University of Hong Kong","doi-asserted-by":"publisher","award":["2022\\u20132024"],"award-info":[{"award-number":["2022\\u20132024"]}],"id":[{"id":"10.13039\/501100004853","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ophthalmology Retina"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.oret.2025.06.005","type":"journal-article","created":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T12:09:20Z","timestamp":1749816560000},"page":"1034-1043","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Macular Hole Closure by Internal Limiting Membrane Flap without Gas Tamponade versus Conventional Surgery"],"prefix":"10.1016","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9377-7377","authenticated-orcid":false,"given":"Simon K.H.","family":"Szeto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4696-9180","authenticated-orcid":false,"given":"Julia T.W.","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy H.Y.","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6677-3265","authenticated-orcid":false,"given":"Christopher M.K.","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy P.H.","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1807-3570","authenticated-orcid":false,"given":"Vivian W.K.","family":"Hui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3724-694X","authenticated-orcid":false,"given":"Ken K.","family":"Tsang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason C.K.","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li Jia","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7832-6428","authenticated-orcid":false,"given":"Timothy Y.Y.","family":"Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaheeda","family":"Mohamed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1884-5015","authenticated-orcid":false,"given":"Chi Wai","family":"Tsang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.oret.2025.06.005_bib1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1136\/bjo.85.1.102","article-title":"Idiopathic full thickness macular hole: natural history and pathogenesis","volume":"85","author":"Ezra","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib2","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1016\/j.ajo.2005.10.021","article-title":"Prevalence of full-thickness macular holes in urban and rural adult Chinese: the Beijing Eye Study","volume":"141","author":"Wang","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib3","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1016\/S0161-6420(01)00581-4","article-title":"Long-term follow-up of unoperated macular holes","volume":"108","author":"Casuso","year":"2001","journal-title":"Ophthalmology"},{"key":"10.1016\/j.oret.2025.06.005_bib4","doi-asserted-by":"crossref","first-page":"P184","DOI":"10.1016\/j.ophtha.2019.09.026","article-title":"Idiopathic macular hole preferred practice pattern\u00ae","volume":"127","author":"Flaxel","year":"2020","journal-title":"Ophthalmology"},{"key":"10.1016\/j.oret.2025.06.005_bib5","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.survophthal.2022.01.006","article-title":"Management of refractory and recurrent macular holes: a comprehensive review","volume":"67","author":"Romano","year":"2022","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib6","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/s41433-020-0844-x","article-title":"Factors affecting anatomical and visual outcome after macular hole surgery: findings from a large prospective UK cohort","volume":"35","author":"Steel","year":"2021","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.oret.2025.06.005_bib7","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.ophtha.2012.09.003","article-title":"United Kingdom National Ophthalmology Database study of vitreoretinal surgery: report 2, macular hole","volume":"120","author":"Jackson","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1016\/j.oret.2025.06.005_bib8","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1038\/s41433-023-02639-0","article-title":"Reducing the use of fluorinated gases in vitreoretinal surgery","volume":"38","author":"Teh","year":"2024","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.oret.2025.06.005_bib9","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1001\/jamaophthalmol.2021.0803","volume":"139","author":"Muni","year":"2021","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib10","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1097\/IAE.0000000000002850","article-title":"Macular hole closure without endotamponade application","volume":"43","author":"Stopa","year":"2023","journal-title":"Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib11","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1097\/IAE.0000000000004201","article-title":"Complex macular hole closure by temporal internal limiting membrane flap without endotamponade","volume":"44","author":"Szeto","year":"2024","journal-title":"Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib12","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1001\/jamasurg.2021.0534","article-title":"ISPOR reporting guidelines for comparative effectiveness research","volume":"156","author":"Massarweh","year":"2021","journal-title":"JAMA Surg"},{"key":"10.1016\/j.oret.2025.06.005_bib13","doi-asserted-by":"crossref","first-page":"e285","DOI":"10.1111\/aos.13601","article-title":"Exploring literature-based definitions of hypotony following glaucoma filtration surgery and the impact on clinical outcomes","volume":"96","author":"Abbas","year":"2018","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib14","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1038\/eye.2015.81","article-title":"Determination of macular hole size in relation to individual variabilities of fovea morphology","volume":"29","author":"Shin","year":"2015","journal-title":"Eye (Lond)"},{"key":"10.1016\/j.oret.2025.06.005_bib15","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1016\/j.ajo.2015.01.022","article-title":"International photographic classification and grading system for myopic maculopathy","volume":"159","author":"Ohno-Matsui","year":"2015","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib16","doi-asserted-by":"crossref","first-page":"1741","DOI":"10.1136\/bjophthalmol-2019-315432","article-title":"Optical coherence tomography-based consensus definition for lamellar macular hole","volume":"104","author":"Hubschman","year":"2020","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib17","doi-asserted-by":"crossref","first-page":"2611","DOI":"10.1016\/j.ophtha.2013.07.042","article-title":"The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole","volume":"120","author":"Duker","year":"2013","journal-title":"Ophthalmology"},{"key":"10.1016\/j.oret.2025.06.005_bib18","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.oret.2022.09.002","article-title":"Dissociated optic nerve fiber layer appearance after macular hole surgery: a randomized controlled trial comparing the temporal inverted internal limiting membrane flap technique with conventional peeling","volume":"7","author":"Ehrhardt","year":"2023","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib19","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1007\/s00417-014-2734-z","article-title":"ILM peeling technique influences the degree of a dissociated optic nerve fibre layer appearance after macular hole surgery","volume":"253","author":"Steel","year":"2015","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib20","doi-asserted-by":"crossref","first-page":"2629","DOI":"10.1007\/s00417-020-04920-4","article-title":"Macular hole closure patterns: an updated classification","volume":"258","author":"Rossi","year":"2020","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib21","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1016\/j.survophthal.2021.02.010","article-title":"Inverted internal limiting membrane flap technique for myopic macular hole: a meta-analysis","volume":"66","author":"Chatziralli","year":"2021","journal-title":"Surv Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.oret.2025.02.003","article-title":"Internal limiting membrane flaps in macular hole surgery: a systematic review and individual participant data meta-analysis","author":"Tzoumas","year":"2025","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib23","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1001\/jamaophthalmol.2017.2207","article-title":"Features involved in the healing process of macular holes","volume":"135","author":"Pertile","year":"2017","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib24","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.ajo.2020.09.023","article-title":"Nasal or temporal internal limiting membrane flap assisted by sub-perfluorocarbon viscoelastic injection for macular hole repair","volume":"223","author":"Chou","year":"2021","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib25","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.ajo.2021.08.016","article-title":"Single-layer inverted internal limiting membrane flap versus conventional peel for small- or medium-sized full-thickness macular holes","volume":"235","author":"Chou","year":"2022","journal-title":"Am J Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib26","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.envint.2008.08.009","article-title":"Environmental hazards and health risk of common liquid perfluoro-n-alkanes, potent greenhouse gases","volume":"35","author":"Tsai","year":"2009","journal-title":"Environ Int"},{"key":"10.1016\/j.oret.2025.06.005_bib27","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1097\/IAE.0000000000001206","article-title":"Closing macular holes with \"macular plug\" without gas tamponade and postoperative posturing","volume":"37","author":"Chakrabarti","year":"2017","journal-title":"Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib28","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1016\/j.oret.2018.12.006","article-title":"Nonsupine positioning after macular hole surgery: a prospective multicenter study","volume":"3","author":"Lindtjorn","year":"2019","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib29","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.oret.2022.06.015","article-title":"Role of positioning after full-thickness macular hole surgery: a systematic review and meta-analysis","volume":"7","author":"Chaudhary","year":"2023","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib30","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1001\/jamaophthalmol.2020.0987","article-title":"Facedown positioning following surgery for large full-thickness macular hole: a multicenter randomized clinical trial","volume":"138","author":"Pasu","year":"2020","journal-title":"JAMA Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib31","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/aos.12844","article-title":"Face-down or no face-down posturing following macular hole surgery: a meta-analysis","volume":"94","author":"Hu","year":"2016","journal-title":"Acta Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib32","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/j.oret.2018.04.022","article-title":"The visual outcomes of macular hole surgery: a registry-based study by the Australian and New Zealand Society of Retinal Specialists","volume":"2","author":"Essex","year":"2018","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib33","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1097\/IAE.0000000000003657","article-title":"Excessive gliosis after vitrectomy for the highly myopic macular hole: a spectral domain optical coherence tomography study","volume":"43","author":"Ye","year":"2023","journal-title":"Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib34","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1007\/s00417-020-04655-2","article-title":"Effects of inverted internal limiting membrane technique and insertion technique on outer retinal restoration associated with glial proliferation in large macular holes","volume":"258","author":"Iwasaki","year":"2020","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib35","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1097\/IAE.0000000000004294","article-title":"Influence of foveal glial tissue after macular hole surgery on outer retinal restoration and visual acuity","volume":"45","author":"Iwasaki","year":"2025","journal-title":"Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib36","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1136\/bjophthalmol-2013-304485","article-title":"A prospective and nationwide study investigating endophthalmitis following pars plana vitrectomy: incidence and risk factors","volume":"98","author":"Park","year":"2014","journal-title":"Br J Ophthalmol"},{"key":"10.1016\/j.oret.2025.06.005_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.oret.2025.02.025","article-title":"Endophthalmitis after pars plana vitrectomy: an 11-year retrospective cohort of 36 179 procedures in London, United Kingdom","author":"Wagner","year":"2025","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib38","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.oret.2022.01.022","article-title":"Epidemiology of acute endophthalmitis after intraocular procedures: a national database study","volume":"6","author":"Baudin","year":"2022","journal-title":"Ophthalmol Retina"},{"key":"10.1016\/j.oret.2025.06.005_bib39","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1097\/APO.0000000000000192","article-title":"Endophthalmitis after pars plana vitrectomy: clinical features, risk factors, and management outcomes","volume":"5","author":"Dave","year":"2016","journal-title":"Asia Pac J Ophthalmol (Phila)"}],"container-title":["Ophthalmology Retina"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468653025002763?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2468653025002763?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T03:26:40Z","timestamp":1772767600000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2468653025002763"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":39,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S2468653025002763"],"URL":"https:\/\/doi.org\/10.1016\/j.oret.2025.06.005","relation":{},"ISSN":["2468-6530"],"issn-type":[{"value":"2468-6530","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Macular Hole Closure by Internal Limiting Membrane Flap without Gas Tamponade versus Conventional Surgery","name":"articletitle","label":"Article Title"},{"value":"Ophthalmology Retina","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.oret.2025.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 by the American Academy of Ophthalmology","name":"copyright","label":"Copyright"}]}}