{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:52:36Z","timestamp":1791420756460,"version":"4.3.3"},"reference-count":97,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Orthodontics"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.ortho.2024.100917","type":"journal-article","created":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T11:42:30Z","timestamp":1724931750000},"page":"100917","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Effect of continuous positive airway pressure therapy on blood levels of IL-6, IL-10, IL-18, IL-1\u03b2, IL-4, and IL-17 in obstructive sleep apnoea adults: A systematic review, meta-analysis and trial sequential analysis"],"prefix":"10.1016","volume":"22","author":[{"given":"Iman","family":"Mohammadi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehrdad","family":"Adibparsa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raya Kh.","family":"Yashooa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad Soroush","family":"Sehat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3586-3012","authenticated-orcid":false,"given":"Masoud","family":"Sadeghi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ortho.2024.100917_bib0490","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/B978-0-323-91532-8.00017-3","article-title":"Obstructive sleep apnea","volume":"189","author":"Pham","year":"2022","journal-title":"Handb Clin Neurol"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0495","first-page":"1","article-title":"Obstructive sleep apnoea syndrome","volume":"1","author":"L\u00e9vy","year":"2015","journal-title":"Nat Rev Dis Primers"},{"issue":"7","key":"10.1016\/j.ortho.2024.100917_bib0500","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.ejim.2012.05.013","article-title":"Obstructive sleep apnea syndrome","volume":"23","author":"Mannarino","year":"2012","journal-title":"Eur J Intern Med"},{"issue":"48","key":"10.1016\/j.ortho.2024.100917_bib0505","doi-asserted-by":"crossref","first-page":"E1481","DOI":"10.1503\/cmaj.170296","article-title":"Diagnosis and treatment of obstructive sleep apnea in adults","volume":"189","author":"Laratta","year":"2017","journal-title":"Can Med Assoc"},{"key":"10.1016\/j.ortho.2024.100917_bib0510","series-title":"The behavioral, molecular, pharmacological, and clinical basis of the sleep-wake cycle","first-page":"103","article-title":"Overview of sleep disorders","author":"Almeneessier","year":"2019"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0515","first-page":"243","article-title":"The sympathetic nervous system and catecholamines metabolism in obstructive sleep apnoea","volume":"8","author":"Bisogni","year":"2016","journal-title":"J Thorac Dis"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0520","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3390\/diseases9040088","article-title":"Association and risk factors for obstructive sleep apnea and cardiovascular diseases: a systematic review","volume":"9","author":"Mitra","year":"2021","journal-title":"Diseases"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0525","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.smrv.2013.01.003","article-title":"Untreated obstructive sleep apnea and the risk for serious long-term adverse outcomes: a systematic review","volume":"18","author":"Kendzerska","year":"2014","journal-title":"Sleep Med Rev"},{"key":"10.1016\/j.ortho.2024.100917_bib0530","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4081\/mrm.2019.10","article-title":"Obstructive sleep apnea and comorbidities: a dangerous liaison","volume":"14","author":"Bonsignore","year":"2019","journal-title":"Multidiscip Respir Med"},{"key":"10.1016\/j.ortho.2024.100917_bib0535","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.sleep.2018.10.026","article-title":"The relationship between obstructive sleep apnea and insomnia: a population-based cross-sectional polysomnographic study","volume":"54","author":"Uhlig","year":"2019","journal-title":"Sleep Med"},{"issue":"7","key":"10.1016\/j.ortho.2024.100917_bib0540","doi-asserted-by":"crossref","first-page":"497","DOI":"10.3109\/00365513.2010.520733","article-title":"Mean platelet volume is increased in patients with severe obstructive sleep apnea","volume":"70","author":"Varol","year":"2010","journal-title":"Scand J Clin Lab Invest"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0545","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1378\/chest.06-2432","article-title":"Positive airway pressure treatment for obstructive sleep apnea","volume":"132","author":"Kakkar","year":"2007","journal-title":"Chest"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0550","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1080\/17476348.2017.1305893","article-title":"Continuous positive airway pressure therapy in obstuctive sleep apnea: benefits and alternatives","volume":"11","author":"Cao","year":"2017","journal-title":"Expert Rev Respir Med"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0555","first-page":"213","article-title":"Otorhinolaryngological aspects of sleep-related breathing disorders","volume":"8","author":"Virk","year":"2016","journal-title":"J Thorac Dis"},{"issue":"8","key":"10.1016\/j.ortho.2024.100917_bib0560","first-page":"1323","article-title":"New developments in the use of positive airway pressure for obstructive sleep apnea","volume":"7","author":"Donovan","year":"2015","journal-title":"J Thorac Dis"},{"issue":"11","key":"10.1016\/j.ortho.2024.100917_bib0565","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1016\/j.sleep.2013.07.006","article-title":"Effects of continuous positive airway pressure therapy on systemic inflammation in obstructive sleep apnea: a meta-analysis","volume":"14","author":"Xie","year":"2013","journal-title":"Sleep Med"},{"key":"10.1016\/j.ortho.2024.100917_bib0570","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s10753-012-9520-z","article-title":"Inflammatory processes and effects of continuous positive airway pressure (CPAP) in overlap syndrome","volume":"36","author":"Nural","year":"2013","journal-title":"Inflammation"},{"issue":"10","key":"10.1016\/j.ortho.2024.100917_bib0575","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.5664\/jcsm.3070","article-title":"Serum inflammatory markers in obstructive sleep apnea: a meta-analysis","volume":"9","author":"Nadeem","year":"2013","journal-title":"J Clin Sleep Med"},{"issue":"5","key":"10.1016\/j.ortho.2024.100917_bib0580","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.3390\/jcm13051484","article-title":"Association of tumor necrosis factor-alpha, interleukin-1\u03b2, interleukin-8, and interferon-\u03b3 with obstructive sleep apnea in both children and adults: a meta-analysis of 102 articles","volume":"13","author":"Golshah","year":"2024","journal-title":"J Clin Med"},{"issue":"6","key":"10.1016\/j.ortho.2024.100917_bib0585","doi-asserted-by":"crossref","first-page":"87","DOI":"10.3390\/life10060087","article-title":"Serum and plasma tumor necrosis factor alpha levels in individuals with obstructive sleep apnea syndrome: a meta-analysis and meta-regression","volume":"10","author":"Imani","year":"2020","journal-title":"Life"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0590","doi-asserted-by":"crossref","first-page":"362","DOI":"10.3390\/life11040362","article-title":"Evaluation of blood levels of c-reactive protein marker in obstructive sleep apnea: a systematic review, meta-analysis and meta-regression","volume":"11","author":"Imani","year":"2021","journal-title":"Life"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0595","doi-asserted-by":"crossref","first-page":"37","DOI":"10.3109\/10408369009105897","article-title":"Interleukins and tumor necrosis factor in inflammation","volume":"28","author":"Warren","year":"1990","journal-title":"Crit Rev Clin Lab Sci"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0600","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/intimm\/dxaa078","article-title":"IL-6 in inflammation, autoimmunity and cancer","volume":"33","author":"Hirano","year":"2021","journal-title":"Int Immunol"},{"issue":"5","key":"10.1016\/j.ortho.2024.100917_bib0605","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1007\/s10753-023-01843-0","article-title":"Interleukin 4 reduces brain hyperexcitability after traumatic injury by downregulating TNF-\u03b1, upregulating IL-10\/TGF-\u03b2, and potential directing macrophage\/microglia to the M2 anti-inflammatory phenotype","volume":"46","author":"Radpour","year":"2023","journal-title":"Inflammation"},{"key":"10.1016\/j.ortho.2024.100917_bib0610","doi-asserted-by":"crossref","first-page":"253","DOI":"10.3389\/fimmu.2014.00253","article-title":"Regulation of the anti-inflammatory cytokines interleukin-4 and interleukin-10 during pregnancy","volume":"5","author":"Chatterjee","year":"2014","journal-title":"Front Immunol"},{"issue":"9","key":"10.1016\/j.ortho.2024.100917_bib0615","doi-asserted-by":"crossref","first-page":"5771","DOI":"10.4049\/jimmunol.180.9.5771","article-title":"IL-10: the master regulator of immunity to infection","volume":"180","author":"Couper","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.ortho.2024.100917_bib0620","doi-asserted-by":"crossref","first-page":"1161067","DOI":"10.3389\/fimmu.2023.1161067","article-title":"The multifaceted nature of IL-10: regulation, role in immunological homeostasis and its relevance to cancer, COVID-19 and post-COVID conditions","volume":"14","author":"Carlini","year":"2023","journal-title":"Front Immunol"},{"issue":"5","key":"10.1016\/j.ortho.2024.100917_bib0625","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1172\/JCI28508","article-title":"The IL-23\/IL-17 axis in inflammation","volume":"116","author":"Iwakura","year":"2006","journal-title":"J Clin Invest"},{"key":"10.1016\/j.ortho.2024.100917_bib0630","doi-asserted-by":"crossref","first-page":"22123","DOI":"10.1021\/acsomega.4c00368","article-title":"Trans-chalcone (1-3-diphenyl-2-propen-1-one) as a therapeutic candidate in joint inflammation via reduction of TNF-\u03b1, IL-1\u03b2, IL-6, and IL-17 in rodents: an in vivo study by RT-PCR and ELISA analysis","volume":"9","author":"Jabbar","year":"2024","journal-title":"ACS Omega"},{"issue":"129","key":"10.1016\/j.ortho.2024.100917_bib0635","first-page":"163","article-title":"The role of interleukin 17A in inducing neutrophilic inflammation in the pulmonary tract","volume":"22","author":"Semik-Orzech","year":"2007","journal-title":"Pol Merkur Lekarski"},{"issue":"14","key":"10.1016\/j.ortho.2024.100917_bib0640","doi-asserted-by":"crossref","first-page":"3720","DOI":"10.1182\/blood-2010-07-273417","article-title":"Interleukin-1 in the pathogenesis and treatment of inflammatory diseases","volume":"117","author":"Dinarello","year":"2011","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0645","doi-asserted-by":"crossref","first-page":"e20190314","DOI":"10.1084\/jem.20190314","article-title":"Inflammasome signaling and regulation of interleukin-1 family cytokines","volume":"217","author":"Chan","year":"2019","journal-title":"J Exp Med"},{"key":"10.1016\/j.ortho.2024.100917_bib0650","doi-asserted-by":"crossref","first-page":"919973","DOI":"10.3389\/fimmu.2022.919973","article-title":"Interleukin-18 cytokine in immunity, inflammation, and autoimmunity: biological role in induction, regulation, and treatment","volume":"13","author":"Ihim","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.ortho.2024.100917_bib0655","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/s11325-018-1662-2","article-title":"Effects of continuous positive airway pressure on cardiovascular biomarkers in patients with obstructive sleep apnea: a meta-analysis of randomized controlled trials","volume":"23","author":"Ning","year":"2019","journal-title":"Sleep Breath"},{"key":"10.1016\/j.ortho.2024.100917_bib0660","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1007\/s11325-015-1288-6","article-title":"Roles of interleukin (IL)-6 gene polymorphisms, serum IL-6 levels, and treatment in obstructive sleep apnea: a meta-analysis","volume":"20","author":"Zhong","year":"2016","journal-title":"Sleep Breath"},{"key":"10.1016\/j.ortho.2024.100917_bib0665","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: an updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0670","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.coph.2004.03.010","article-title":"Therapeutic strategies to reduce IL-1 activity in treating local and systemic inflammation","volume":"4","author":"Dinarello","year":"2004","journal-title":"Curr Opin Pharmacol"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0675","first-page":"719","article-title":"Statistical aspects of the analysis of data from retrospective studies of disease","volume":"22","author":"Mantel","year":"1959","journal-title":"J Natl Cancer Inst"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0680","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1080\/00401706.1988.10488400","article-title":"Graphical display of estimates having differing standard errors","volume":"30","author":"Galbraith","year":"1988","journal-title":"Technometrics"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0685","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1183\/09031936.00007008","article-title":"CPAP decreases plasma levels of soluble tumour necrosis factor-alpha receptor 1 in obstructive sleep apnoea","volume":"32","author":"Arias","year":"2008","journal-title":"Eur Respir J"},{"issue":"31","key":"10.1016\/j.ortho.2024.100917_bib0690","first-page":"71","article-title":"Changes of serum interleukin-8 and monocyte chemoattractant protein-1 levels in patients with obstructive sleep apnea hypopnea syndrome","volume":"9","author":"Bao","year":"2005","journal-title":"Chin J Clin Rehabil"},{"issue":"8","key":"10.1016\/j.ortho.2024.100917_bib0695","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1017\/S0022215117001116","article-title":"Effect of modern surgical treatment on the inflammatory\/anti-inflammatory balance in patients with obstructive sleep apnoea","volume":"131","author":"Binar","year":"2017","journal-title":"J Laryngol Otol"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0700","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s11325-019-01898-0","article-title":"Oxidative stress and inflammatory profiles in obstructive sleep apnea: are short-term CPAP or aerobic exercise therapies effective?","volume":"24","author":"Borges","year":"2020","journal-title":"Sleep Breath"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0705","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1183\/09031936.00138207","article-title":"Clock gene dysfunction in patients with obstructive sleep apnoea syndrome","volume":"32","author":"Burioka","year":"2008","journal-title":"Eur Respir J"},{"issue":"6","key":"10.1016\/j.ortho.2024.100917_bib0710","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1089\/met.2009.0019","article-title":"Continuous positive airway pressure therapy improves hypoadiponectinemia in severe obese men with obstructive sleep apnea without changes in insulin resistance","volume":"7","author":"Carneiro","year":"2009","journal-title":"Metab Syndr Relat Disord"},{"key":"10.1016\/j.ortho.2024.100917_bib0715","doi-asserted-by":"crossref","first-page":"109604","DOI":"10.1016\/j.intimp.2022.109604","article-title":"IL-33\/ST2 mediating systemic inflammation and neuroinflammation through NF-kB participated in the neurocognitive impairment in obstructive sleep apnea","volume":"115","author":"Dandan","year":"2023","journal-title":"Int Immunopharmacol"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0720","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5604\/00306657.1147029","article-title":"Changes in ghrelin, leptin and pro-inflammatory cytokines after therapy in Obstructive Sleep Apnea Syndrome (OSAS) patients","volume":"69","author":"De Santis","year":"2015","journal-title":"Otolaryngol Pol"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0725","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1378\/chest.08-0556","article-title":"Effects of continuous positive airway pressure on cardiovascular risk profile in patients with severe obstructive sleep apnea and metabolic syndrome","volume":"134","author":"Dorkova","year":"2008","journal-title":"Chest"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0730","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1093\/ajh\/hpab169","article-title":"Pathways of microcirculatory endothelial dysfunction in obstructive sleep apnea: a comprehensive ex vivo evaluation in human tissue","volume":"35","author":"Gavrilin","year":"2022","journal-title":"Am J Hypertens"},{"issue":"9","key":"10.1016\/j.ortho.2024.100917_bib0735","first-page":"Cr510","article-title":"Resistin levels in patients with obstructive sleep apnoea syndrome\u00a0\u2013\u00a0the link to subclinical inflammation?","volume":"10","author":"Harsch","year":"2004","journal-title":"Med Sci Monit"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0740","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1017\/S0022215114002990","article-title":"Tumour necrosis factor-\u03b1\/interleukin-10 ratio in patients with obstructive sleep apnoea hypopnoea syndrome","volume":"129","author":"Jiang","year":"2015","journal-title":"J Laryngol Otol"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0745","first-page":"467","article-title":"Influence of continuous positive airway pressure ventilation and N-acetylcysteine treatment on the levels of serum oxidative stress and inflammatory markers in the patients with moderate-severe OSAHS","volume":"40","author":"Jianyong","year":"2019","journal-title":"Med J Wuhan Univ"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0750","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1007\/s11325-012-0761-8","article-title":"Influence of CPAP treatment on airway and systemic inflammation in OSAS patients","volume":"18","author":"Karamanl\u0131","year":"2014","journal-title":"Sleep Breath"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0755","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1136\/thx.2008.097931","article-title":"Effects of continuous positive airway pressure on systemic inflammation in patients with moderate to severe obstructive sleep apnoea: a randomised controlled trial","volume":"64","author":"Kohler","year":"2009","journal-title":"Thorax"},{"key":"10.1016\/j.ortho.2024.100917_bib0760","doi-asserted-by":"crossref","first-page":"103806","DOI":"10.1016\/j.resp.2021.103806","article-title":"Association between Interleukin-6 and vitamin D serum levels in patients with obstructive sleep apnea syndrome and impact of long-term continuous positive airway pressure therapy on biomarker levels","volume":"296","author":"Kotsiou","year":"2022","journal-title":"Respir Physiol Neurobiol"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0765","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1183\/09031936.00126712","article-title":"Sleep apnoea, sleepiness, inflammation and insulin resistance in middle-aged males and females","volume":"43","author":"Kritikou","year":"2014","journal-title":"Eur Respir J"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0770","doi-asserted-by":"crossref","first-page":"24","DOI":"10.3901\/JME.2011.01.024","article-title":"Association among plasma interleukin-18 levels, carotid intima-media thickness and severity of obstructive sleep apnea","volume":"122","author":"Li","year":"2009","journal-title":"Chin Med J (Engl)"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0775","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1159\/000119542","article-title":"Are biomarker levels a good follow-up tool for evaluating obstructive sleep apnea syndrome treatments?","volume":"76","author":"Li","year":"2008","journal-title":"Respiration"},{"issue":"10","key":"10.1016\/j.ortho.2024.100917_bib0780","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.arbres.2014.02.016","article-title":"Effect of continuous positive airway pressure and upper airway surgery on exhaled breath condensate and serum biomarkers in patients with sleep apnea","volume":"50","author":"Lloberes","year":"2014","journal-title":"Arch Bronconeumol"},{"issue":"4\u20135","key":"10.1016\/j.ortho.2024.100917_bib0785","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.clinbiochem.2014.09.005","article-title":"Comprehensive biomarker profiling in patients with obstructive sleep apnea","volume":"48","author":"Maeder","year":"2015","journal-title":"Clin Biochem"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0790","doi-asserted-by":"crossref","first-page":"166","DOI":"10.4103\/atm.atm_37_22","article-title":"Continuous positive airway pressure therapy suppresses inflammatory cytokines and improves glucocorticoid responsiveness in patients with obstructive sleep apnea and asthma: a case-control study","volume":"17","author":"Mahboub","year":"2022","journal-title":"Ann Thorac Med"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0795","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1002\/clc.21010","article-title":"Continuous positive airway pressure therapy improves vascular dysfunction and decreases oxidative stress in patients with the metabolic syndrome and obstructive sleep apnea syndrome","volume":"35","author":"Oyama","year":"2012","journal-title":"Clin Cardiol"},{"issue":"17","key":"10.1016\/j.ortho.2024.100917_bib0800","doi-asserted-by":"crossref","first-page":"e94379","DOI":"10.1172\/jci.insight.94379","article-title":"Correction of intermittent hypoxia reduces inflammation in obese subjects with obstructive sleep apnea","volume":"2","author":"Perrini","year":"2017","journal-title":"JCI Insight"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0805","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1007\/s11325-024-02997-3","article-title":"Effect of continuous positive airway pressure treatment on Th17\/Treg imbalance in patients with obstructive sleep apnea and a preliminary study on its mechanism","volume":"28","author":"Shen","year":"2024","journal-title":"Sleep Breath"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0810","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1093\/sleep\/32.4.537","article-title":"Long-term effect of continuous positive airway pressure therapy on inflammation markers of patients with obstructive sleep apnea syndrome","volume":"32","author":"Steiropoulos","year":"2009","journal-title":"Sleep"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0815","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/thoraxjnl-2014-205958","article-title":"Markers of inflammation: data from the MOSAIC randomised trial of CPAP for minimally symptomatic OSA","volume":"70","author":"Stradling","year":"2015","journal-title":"Thorax"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0820","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1089\/ars.2007.1949","article-title":"Plasma thioredoxin, a novel oxidative stress marker, in patients with obstructive sleep apnea before and after nasal continuous positive airway pressure","volume":"10","author":"Takahashi","year":"2008","journal-title":"Antioxid Redox Signal"},{"issue":"12","key":"10.1016\/j.ortho.2024.100917_bib0825","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1164\/rccm.200402-193OC","article-title":"Increased levels and activity of matrix metalloproteinase-9 in obstructive sleep apnea syndrome","volume":"170","author":"Tazaki","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0830","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.diabet.2016.12.002","article-title":"Adipose tissue is influenced by hypoxia of obstructive sleep apnea syndrome independent of obesity","volume":"43","author":"Thorn","year":"2017","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.ortho.2024.100917_bib0835","doi-asserted-by":"crossref","first-page":"zsx157","DOI":"10.1093\/sleep\/zsx157","article-title":"CPAP does not reduce inflammatory biomarkers in patients with coronary artery disease and nonsleepy obstructive sleep apnea: a randomized controlled trial","volume":"40","author":"Thunstr\u00f6m","year":"2017","journal-title":"Sleep"},{"issue":"8","key":"10.1016\/j.ortho.2024.100917_bib0840","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s00198-007-0556-0","article-title":"Link between obstructive sleep apnea and increased bone resorption in men","volume":"19","author":"Tomiyama","year":"2008","journal-title":"Osteoporos Int"},{"issue":"1","key":"10.1016\/j.ortho.2024.100917_bib0845","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s11325-022-02616-z","article-title":"The effect of continuous positive airway pressure treatment on inflammatory parameters and periostin levels in patients with obstructive sleep apnea syndrome","volume":"27","author":"Tosun","year":"2023","journal-title":"Sleep Breath"},{"key":"10.1016\/j.ortho.2024.100917_bib0850","doi-asserted-by":"crossref","first-page":"518920","DOI":"10.1155\/2014\/518920","article-title":"Relationships between obstructive sleep apnea syndrome, continuous positive airway pressure treatment, and inflammatory cytokines","volume":"2014","author":"Un\u00fcvar Do\u011fan","year":"2014","journal-title":"Sleep Disord"},{"issue":"8","key":"10.1016\/j.ortho.2024.100917_bib0855","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1111\/j.1365-2362.2008.01984.x","article-title":"Selective effects of CPAP on sleep apnoea-associated manifestations","volume":"38","author":"Vgontzas","year":"2008","journal-title":"Eur J Clin Invest"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0860","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1183\/13993003.00234-2016","article-title":"Upper airway and systemic inflammation in obstructive sleep apnoea","volume":"48","author":"Vicente","year":"2016","journal-title":"Eur Respir J"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0865","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s11325-020-02149-3","article-title":"The utility of proinflammatory markers in patients with obstructive sleep apnea","volume":"25","author":"Wali","year":"2021","journal-title":"Sleep Breath"},{"issue":"6","key":"10.1016\/j.ortho.2024.100917_bib0870","doi-asserted-by":"crossref","first-page":"102655","DOI":"10.1016\/j.amjoto.2020.102655","article-title":"Continuous positive airway pressure effectively ameliorates arrhythmias in patients with obstructive sleep apnea-hypopnea via counteracting the inflammation","volume":"41","author":"Wang","year":"2020","journal-title":"Am J Otolaryngol"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0875","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1159\/000141866","article-title":"Resistin is closely related to systemic inflammation in obstructive sleep apnea","volume":"76","author":"Yamamoto","year":"2008","journal-title":"Respiration"},{"issue":"6","key":"10.1016\/j.ortho.2024.100917_bib0880","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s00408-010-9253-4","article-title":"Quantification of circulating cell-free DNA in the serum of patients with obstructive sleep apnea-hypopnea syndrome","volume":"188","author":"Ye","year":"2010","journal-title":"Lung"},{"issue":"8","key":"10.1016\/j.ortho.2024.100917_bib0885","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1161\/01.CIR.0000052627.99976.18","article-title":"Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure","volume":"107","author":"Yokoe","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.ortho.2024.100917_bib0890","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.sleep.2022.09.018","article-title":"Involvement of Galectin-3 in neurocognitive impairment in obstructive sleep apnea via regulating inflammation and oxidative stress through NLRP3","volume":"101","author":"Zong","year":"2023","journal-title":"Sleep Med"},{"key":"10.1016\/j.ortho.2024.100917_bib0895","first-page":"2459","article-title":"Obstructive sleep apnea syndrome: from symptoms to treatment","volume":"19","author":"Iannella","year":"2022","journal-title":"MDPI"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0900","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1007\/s11739-022-02983-1","article-title":"Treatment options in obstructive sleep apnea","volume":"17","author":"Gambino","year":"2022","journal-title":"Intern Emerg Med"},{"issue":"17","key":"10.1016\/j.ortho.2024.100917_bib0905","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.1161\/CIRCULATIONAHA.105.556746","article-title":"Selective activation of inflammatory pathways by intermittent hypoxia in obstructive sleep apnea syndrome","volume":"112","author":"Ryan","year":"2005","journal-title":"Circulation"},{"key":"10.1016\/j.ortho.2024.100917_bib0910","first-page":"1","article-title":"Is there a relationship between the severity of obstructive sleep apnea syndrome and the systemic immune inflammation index?","author":"G\u00f6len","year":"2024","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"10.1016\/j.ortho.2024.100917_bib0915","doi-asserted-by":"crossref","first-page":"932596","DOI":"10.3389\/fphys.2022.932596","article-title":"Circadian clock disruptions link oxidative stress and systemic inflammation to metabolic syndrome in obstructive sleep apnea patients","volume":"13","author":"Li","year":"2022","journal-title":"Front Physiol"},{"issue":"2","key":"10.1016\/j.ortho.2024.100917_bib0920","doi-asserted-by":"crossref","first-page":"159","DOI":"10.21053\/ceo.2022.01368","article-title":"Associations between systemic inflammatory markers based on blood cells and polysomnographic factors in obstructive sleep apnea","volume":"16","author":"Kim","year":"2023","journal-title":"Clin Exp Otorhinolaryngol"},{"issue":"9","key":"10.1016\/j.ortho.2024.100917_bib0925","doi-asserted-by":"crossref","first-page":"e0255708","DOI":"10.1371\/journal.pone.0255708","article-title":"Identification of key genes and immune infiltration modulated by CPAP in obstructive sleep apnea by integrated bioinformatics analysis","volume":"16","author":"Fan","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.ortho.2024.100917_bib0930","doi-asserted-by":"crossref","first-page":"101568","DOI":"10.1016\/j.smrv.2021.101568","article-title":"Obstructive sleep apnea and stroke: the mechanisms, the randomized trials, and the road ahead","volume":"61","author":"Javaheri","year":"2022","journal-title":"Sleep Med Rev"},{"issue":"7","key":"10.1016\/j.ortho.2024.100917_bib0935","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.jacc.2016.11.069","article-title":"Sleep apnea: types, mechanisms, and clinical cardiovascular consequences","volume":"69","author":"Javaheri","year":"2017","journal-title":"J Am Coll Cardiol"},{"issue":"7","key":"10.1016\/j.ortho.2024.100917_bib0940","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1089\/jir.2024.0057","article-title":"Evaluation of serum\/plasma levels of interleukins (IL-6, IL-12, IL-17, IL-18, and IL-23) in adults and children with obstructive sleep apnea: a systematic review, meta-analysis, and trial sequential analysis","volume":"44","author":"Golshah","year":"2024","journal-title":"J Interferon Cytokine Res"},{"key":"10.1016\/j.ortho.2024.100917_bib0945","first-page":"1343","article-title":"Evaluation of serum and plasma interleukin-6 levels in obstructive sleep apnea syndrome: a meta-analysis and meta-regression","volume":"11","author":"Imani","year":"2020","journal-title":"Front Physiol"},{"issue":"7","key":"10.1016\/j.ortho.2024.100917_bib0950","doi-asserted-by":"crossref","first-page":"147","DOI":"10.21037\/atm.2019.02.34","article-title":"Anti-inflammatory therapy for cardiovascular disease","volume":"7","author":"Kosmas","year":"2019","journal-title":"Ann Transl Med"},{"issue":"3","key":"10.1016\/j.ortho.2024.100917_bib0955","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s10787-018-0458-0","article-title":"IL-6 signalling pathways and the development of type 2 diabetes","volume":"26","author":"Akbari","year":"2018","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.ortho.2024.100917_bib0960","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.neurobiolaging.2015.10.039","article-title":"The inflammatory markers CRP, IL-6, and IL-10 are associated with cognitive function\u00a0\u2013\u00a0data from the Berlin Aging Study II","volume":"38","author":"Tegeler","year":"2016","journal-title":"Neurobiol Aging"},{"issue":"4","key":"10.1016\/j.ortho.2024.100917_bib0965","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1164\/rccm.200608-1190PP","article-title":"Cardiovascular morbidity in obstructive sleep apnea: oxidative stress, inflammation, and much more","volume":"177","author":"Gozal","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.ortho.2024.100917_bib0970","doi-asserted-by":"crossref","first-page":"1027894","DOI":"10.3389\/fped.2022.1027894","article-title":"Relationship between serum brain-derived neurotrophic factor and cognitive impairment in children with sleep-disordered breathing","volume":"10","author":"Feng","year":"2022","journal-title":"Front Pediatr"}],"container-title":["International Orthodontics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1761722724000731?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1761722724000731?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,14]],"date-time":"2024-11-14T07:51:39Z","timestamp":1731570699000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1761722724000731"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":97,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S1761722724000731"],"URL":"https:\/\/doi.org\/10.1016\/j.ortho.2024.100917","relation":{},"ISSN":["1761-7227"],"issn-type":[{"value":"1761-7227","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of continuous positive airway pressure therapy on blood levels of IL-6, IL-10, IL-18, IL-1\u03b2, IL-4, and IL-17 in obstructive sleep apnoea adults: A systematic review, meta-analysis and trial sequential analysis","name":"articletitle","label":"Article Title"},{"value":"International Orthodontics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ortho.2024.100917","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 CEO. Published by Elsevier Masson SAS. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"100917"}}