{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:22:04Z","timestamp":1791044524334,"version":"4.1.0"},"reference-count":40,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":306,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Purpose<\/jats:italic>: While the etiology of de Quervain's disease is unknown, repetitive motion coupled with awkward wrist position and septation within the first dorsal compartment are considered causative factors. We hypothesize that these conditions might produce high gliding resistance, which could then induce micro\u2010damage of the tendons and retinaculum. The purpose of this study was to measure the gliding resistance of the extensor pollicis brevis and abductor pollicis longus tendons within the first dorsal compartment in a human cadaver model.<\/jats:p><jats:p><jats:italic>Methods<\/jats:italic>: Fifteen human cadaver wrists, which included eight septation and seven non\u2010septation wrists in the first dorsal compartment, were used. Gliding resistance of the extensor pollicis brevis and abductor pollicis longus tendons was measured in seven wrist positions: 60\u00b0 extension, 30\u00b0 extension, 0\u00b0, 30\u00b0 flexion, 60\u00b0 flexion in neutral deviation and 30\u00b0 ulnar deviation, 15\u00b0 radial deviation in neutral extension\/flexion.<\/jats:p><jats:p><jats:italic>Results<\/jats:italic>: The overall gliding resistance was not different between septation and non\u2010septation wrists (0.21 versus 0.19 N for abductor pollicis longus and 0.21 versus 0.15 N for extensor pollicis brevis, respectively), but there was a significant effect on gliding resistance due to wrist position (<jats:italic>p<\/jats:italic> &lt; 0.05) in both tendons. Interaction between wrist position and septation status was observed in the extensor pollicis brevis tendon (<jats:italic>p<\/jats:italic> &lt; 0.05). With septation, the gliding resistance of the extensor pollicis brevis was significantly higher in 60\u00b0 wrist flexion (0.51 N) compared to all other wrist positions tested (all less than 0.26 N) (<jats:italic>p<\/jats:italic> &lt; 0.05). In the non\u2010septation group, gliding resistance was significantly higher in 60\u00b0 flexion (0.20 N) and 60\u00b0 extension (0.22 N) compared to the other five wrist positions (all less than 0.15 N) (<jats:italic>p<\/jats:italic> &lt; 0.05). Although no significant difference was observed, the extensor pollicis brevis tendon with septation tended to have higher gliding resistance than that without septation in wrist flexion. In 60\u00b0 of wrist flexion the abductor pollicis longus tendon had significantly higher gliding resistance (0.33 N) than the other wrist positions (all less than 0.26 N) (<jats:italic>p<\/jats:italic> &lt; 0.05).<\/jats:p><jats:p><jats:italic>Conclusions<\/jats:italic>: A combination of septation and wrist position significantly affected extensor pollicis brevis tendon gliding resistance in this cadaver model. These factors may contribute to the development of de Quervain's disease. \u00a9 2004 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved.<\/jats:p>","DOI":"10.1016\/j.orthres.2004.06.014","type":"journal-article","created":{"date-parts":[[2004,8,25]],"date-time":"2004-08-25T15:32:18Z","timestamp":1093447938000},"page":"243-248","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Gliding resistance of the extensor pollicis brevis tendon and abductor pollicis longus tendon within the first dorsal compartment in fixed wrist positions"],"prefix":"10.1002","volume":"23","author":[{"given":"Keiji","family":"Kutsumi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter C.","family":"Amadio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfeng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark 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