{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T21:55:00Z","timestamp":1773006900672,"version":"3.50.1"},"reference-count":41,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":184,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Journal Orthopaedic Research"],"published-print":{"date-parts":[[2005,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:italic>Purpose:<\/jats:italic> This study investigated the biomechanics of the sciatic nerve with hind limb positioning in live and euthanized Sprague\u2010Dawley rats after traumatic nerve injury.<\/jats:p><jats:p><jats:italic>Methods:<\/jats:italic> With radiographic analysis, sciatic nerve excursion and strain were measured in situ during a modified straight leg raise, which included sequential hip flexion and ankle dorsiflexion. Comparisons were made between nerves in uninjured, sham\u2010injured and mild crush\u2010injured rats at the 7\u2010day and 21\u2010day recovery times.<\/jats:p><jats:p><jats:italic>Results:<\/jats:italic> Significant strain and proximal excursion of the sciatic nerve were observed in all groups during hip flexion, and additional increased strain was noted during dorsiflexion. Seven days after nerve injury, strain increased significantly during hip flexion (17.64 \u00b1 14.12%;<jats:italic>p<\/jats:italic> = 0.0091) and dorsiflexion (22.56 \u00b1 15.47%;<jats:italic>p<\/jats:italic> = 0.0082) compared to the sham\u2010injured controls. At 21 days after injury, the strains were similar between the injured and sham\u2010injured groups.<\/jats:p><jats:p><jats:italic>Conclusions:<\/jats:italic> Nerve bed elongation during straight leg raise causes sciatic nerve strain and excursion towards the moving joint with the greatest movement nearest the moving joint. In the first week after injury, the maximal strain exceeded the level previously shown to impair nerve conduction and circulation. \u00a9 2004 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved.<\/jats:p>","DOI":"10.1016\/j.orthres.2004.11.008","type":"journal-article","created":{"date-parts":[[2005,1,27]],"date-time":"2005-01-27T12:53:17Z","timestamp":1106830397000},"page":"764-770","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["Strain and excursion in the rat sciatic nerve during a modified straight leg raise are altered after traumatic nerve injury"],"prefix":"10.1002","volume":"23","author":[{"given":"Benjamin S.","family":"Boyd","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Puttlitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jerylin","family":"Gan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kimberly S.","family":"Topp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(05)80464-2"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(97)80118-9"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9290(84)90009-5"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0363-5023(80)80037-2"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00007632-197905000-00011"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9406(10)62374-7"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1053\/jhsu.2002.35886"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(51)93353-3"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(92)90316-H"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0266-7681(93)90206-U"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0033(03)00176-1"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0004-9514(14)60655-3"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0266-7681(03)00107-4"},{"key":"e_1_2_1_15_2","first-page":"44","article-title":"Observations on straight leg\u2010raising with special reference to nerve root adhesions","volume":"9","author":"Fahrni WH","year":"1966","journal-title":"Can J Surg"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1113\/expphysiol.1994.sp003791"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.85B3.13220"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-199203000-00011"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.28.1.12"},{"key":"e_1_2_1_20_2","first-page":"167","volume-title":"Physical therapy of the cervical and thoracic spine","author":"Kenneally M","year":"1988"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1997.6601"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0268-0033(99)00042-X"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/0268-0033(95)99801-8"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.3109\/17453679209154780"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.39.6.566"},{"key":"e_1_2_1_26_2","first-page":"76","article-title":"Mechanical properties of peripheral nerve","volume":"314","author":"Millesi H","year":"1995","journal-title":"Clin Orthop"},{"key":"e_1_2_1_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(85)90119-0"},{"key":"e_1_2_1_28_2","first-page":"10","article-title":"Blood flow of peripheral nerve effects of dissection, stretching and compression","volume":"11","author":"Ogata K","year":"1985","journal-title":"J Hand Surg Br"},{"key":"e_1_2_1_29_2","doi-asserted-by":"crossref","unstructured":"PhillipsJ SmitX DeZoysaN. et al. 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