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In this study, we used immunogold labeling to localize collagen types within the SSCT in three cadaver specimens and three patients with carpal tunnel syndrome. Positive labeling for collagen types I, III and VI was found with immunoelectron microscopy. Collagen types I and III were codistributed within the SSCT. Type VI was primarily located in microfibrillar structures between collagen bundles, between elastin and collagen bundles and between collagen bundles and cells. There was no difference in the distribution of collagen types when comparing cadaver specimens and carpal tunnel patients. \u00a9 2005 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved.<\/jats:p>","DOI":"10.1016\/j.orthres.2005.02.009","type":"journal-article","created":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T15:37:19Z","timestamp":1117208239000},"page":"1226-1231","update-policy":"http:\/\/dx.doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Immunolocalization of collagen types in the subsynovial connective tissue within the carpal tunnel in humans"],"prefix":"10.1002","volume":"23","author":[{"given":"Jinrok","family":"Oh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunfeng","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter C.","family":"Amadio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai\u2010Nan","family":"An","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark E.","family":"Zobitz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lester E.","family":"Wold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2006,1]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(94)90016-7"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0968-4328(00)00043-3"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M101182200"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0309-1651(84)90072-9"},{"key":"e_1_2_1_6_2","volume-title":"Biology of extracellular matrix: A series, regulation of matrix accumulation","author":"Davidson JM","year":"1986"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200407000-00014"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ar.10162"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0266-7681(86)90035-5"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0363-5023(91)90208-S"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001430304"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/13.2.303"},{"key":"e_1_2_1_13_2","unstructured":"GuimberteauJ. 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