{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T14:46:25Z","timestamp":1778942785300,"version":"3.51.4"},"reference-count":164,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,10,1]],"date-time":"2004-10-01T00:00:00Z","timestamp":1096588800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Otolaryngologic Clinics of North America"],"published-print":{"date-parts":[[2004,10]]},"DOI":"10.1016\/j.otc.2004.03.005","type":"journal-article","created":{"date-parts":[[2005,4,18]],"date-time":"2005-04-18T14:53:11Z","timestamp":1113835991000},"page":"973-990","source":"Crossref","is-referenced-by-count":31,"title":["Intratympanic treatment of hearing loss with novel and traditional agents"],"prefix":"10.1016","volume":"37","author":[{"given":"Michael D.","family":"Seidman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Prashant","family":"Vivek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.otc.2004.03.005_BIB1","series-title":"Fact sheet on noise-induced hearing loss","year":"1998"},{"issue":"9","key":"10.1016\/j.otc.2004.03.005_BIB2","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1093\/oxfordjournals.aje.a009713","article-title":"Prevalence of hearing loss in older adults in Beaver Dam, Wisconsin: The Epidemiology of Hearing Loss Study","volume":"148","author":"Cruickshanks","year":"1998","journal-title":"Am J Epidemiol"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB3","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1177\/019459988910000402","article-title":"Goals and mechanisms for training otolaryngologists in the area of geriatric medicine","volume":"100","author":"Johns","year":"1989","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB4","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1097\/00129492-200107000-00011","article-title":"Targeted topical steroid therapy in sudden sensorineural hearing loss","volume":"22","author":"Kopke","year":"2001","journal-title":"Otol Neurotol"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB5","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0006-8993(01)02164-3","article-title":"Reactive nitrogen species contribute to blood labyrinth barrier disruption in suppurative labyrinthitis complicating experimental pneumococcal meningitis in the rat","volume":"904","author":"Kastenbauer","year":"2001","journal-title":"Brain Res"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB6","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/0378-5955(96)00075-5","article-title":"Direct detection of ototoxicant induced reactive oxygen species generation in cochlear explants","volume":"98","author":"Clerici","year":"1996","journal-title":"Hear Res"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB7","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1067\/mhn.2002.125299","article-title":"Round window application of D-methionine provides complete cisplatin otoprotection","volume":"126","author":"Korver","year":"2002","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB8","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0378-5955(00)00096-4","article-title":"Glutathione limits noise-induced hearing loss","volume":"146","author":"Ohinata","year":"2000","journal-title":"Hear Res"},{"issue":"7","key":"10.1016\/j.otc.2004.03.005_BIB9","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1097\/00005537-200107000-00005","article-title":"L-N-acetyl-cysteine protection against cisplatin-induced auditory neuronal and hair cell toxicity","volume":"111","author":"Feghali","year":"2001","journal-title":"Laryngoscope"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5955(00)00072-1","article-title":"Upregulation of glial cell line-derived neurotrophic factor (GDNF) in the rat cochlea following noise","volume":"146","author":"Nam","year":"2000","journal-title":"Hear Res"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB11","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1067\/mhn.2003.50","article-title":"Diagnosis and treatment of sudden-onset sensorineural hearing loss: a study of 51 patients","volume":"128","author":"Zadeh","year":"2003","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB12","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1177\/019459989310900408","article-title":"Diuretic and diet effect on Meniere's disease evaluated by the 1985 Committee on Hearing and Equilibrium guidelines","volume":"109","author":"Santos","year":"1993","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB13","first-page":"295","article-title":"Diatrizoate and dextran treatment of sudden sensorineural hearing loss","volume":"16","author":"Redleaf","year":"1995","journal-title":"Am J Otol"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB14","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1159\/000058303","article-title":"From gene identification to gene therapy","volume":"7","author":"Kanzaki","year":"2002","journal-title":"Audiol Neurootol"},{"issue":"23","key":"10.1016\/j.otc.2004.03.005_BIB15","doi-asserted-by":"crossref","first-page":"13495","DOI":"10.1073\/pnas.2334503100","article-title":"Generation of hair cells by stepwise differentiation of embryonic stem cells","volume":"100","author":"Li","year":"2003","journal-title":"Proc Natl Acad Sci USA"},{"issue":"2 Pt 1","key":"10.1016\/j.otc.2004.03.005_BIB16","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1177\/000348948109000208","article-title":"Nature of blood-labyrinth barrier in experimental conditions","volume":"90","author":"Juhn","year":"1981","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"5\u20136","key":"10.1016\/j.otc.2004.03.005_BIB17","doi-asserted-by":"crossref","first-page":"529","DOI":"10.3109\/00016488109138538","article-title":"Labyrinthine barriers and cochlear homeostasis","volume":"91","author":"Juhn","year":"1981","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.otc.2004.03.005_BIB18","doi-asserted-by":"crossref","first-page":"201","DOI":"10.3109\/00016483609123219","article-title":"Die Beinflussung des Ohrensausens durch intraven\u0161s injizierte Lokalanaestetica","volume":"23","author":"Barany","year":"1935","journal-title":"Acta Otlaryngol"},{"issue":"Suppl","key":"10.1016\/j.otc.2004.03.005_BIB19","first-page":"1","article-title":"Ablation therapy in the management of Meniere's disease","volume":"132","author":"Schuknecht","year":"1957","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.otc.2004.03.005_BIB20","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.5631\/jibirin.75.2525","article-title":"Pathology and treatment of cochlear tinnitus by blocking with 4% lidocaine and Decadron infusion","volume":"75","author":"Sakata","year":"1982","journal-title":"Practica Otologica (Kyoto)"},{"key":"10.1016\/j.otc.2004.03.005_BIB21","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S1043-1810(01)80012-9","article-title":"Microdose gentamicin delivered via the Round Window Microcathter: a therapeutic option in Meniere's disease","volume":"12","author":"Weisskopf","year":"2001","journal-title":"Oper Tech Otolaryngol Head Neck Surg"},{"key":"10.1016\/j.otc.2004.03.005_BIB22","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/S1043-1810(01)80009-9","article-title":"Silverstein Microwick for the treatment of the inner ear","volume":"12","author":"Silverstein","year":"2001","journal-title":"Operative Techniques in Otolaryngology-Head and Neck Surgery"},{"key":"10.1016\/j.otc.2004.03.005_BIB23","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1177\/014556139607500806","article-title":"Intratympanic steroid treatment of inner ear disease and tinnitus (preliminary report)","volume":"75","author":"Silverstein","year":"1996","journal-title":"Ear Nose Throat J"},{"issue":"5 Pt 1","key":"10.1016\/j.otc.2004.03.005_BIB24","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1288\/00005537-198405000-00016","article-title":"Steroid use in idiopathic sudden sensorineural hearing loss","volume":"94","author":"Moskowitz","year":"1984","journal-title":"Laryngoscope"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB25","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1001\/archotol.1990.01870060058010","article-title":"The beneficial effect of methylprednisolone in acute vestibular vertigo","volume":"116","author":"Ariyasu","year":"1990","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB26","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/S0030-6665(20)30398-4","article-title":"Dexamethasone perfusion of the labyrinth plus intravenous dexamethasone for Meniere's disease","volume":"29","author":"Shea","year":"1996","journal-title":"Otolaryngol Clin North Am"},{"issue":"8","key":"10.1016\/j.otc.2004.03.005_BIB27","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1001\/jama.1994.03520080053043","article-title":"Serum antibody to inner ear proteins with progressive hearing loss. Correlation with disease activity and response to corticosteroid treatment","volume":"272","author":"Moscicki","year":"1994","journal-title":"JAMA"},{"issue":"7 Part 2","key":"10.1016\/j.otc.2004.03.005_BIB28","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00005537-199907001-00001","article-title":"Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application","volume":"109","author":"Parnes","year":"1999","journal-title":"Laryngoscope"},{"key":"10.1016\/j.otc.2004.03.005_BIB29","series-title":"Goodman and Gilman's the pharmacological basis of therapeutics","first-page":"1459","article-title":"Adrenocorticotrophic hormone; adrenocortical steroids and their synthetic analogs; inhibitors of the synthesis and actions of adrenocortical hormones","author":"Shimmer","year":"1996"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB30","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0378-5955(01)00240-4","article-title":"Aldosterone and prednisolone control of cochlear function in MRL\/MpJ-Fas autoimmune mice","volume":"155","author":"Trune","year":"2001","journal-title":"Hear Res"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB31","first-page":"230","article-title":"Effect of transtympanic injection of steroids on cochlear blood flow, auditory sensitivity, and histology in the guinea pig","volume":"19","author":"Shirwany","year":"1998","journal-title":"Am J Otol"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB32","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0378-5955(03)00078-9","article-title":"Glucocorticoids and dehydroepiandrosterone sulfate ameliorate ischemia-induced injury of the cochlea","volume":"180","author":"Tabuchi","year":"2003","journal-title":"Hear Res"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB33","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0378-5955(91)90201-J","article-title":"Noise induced changes in red blood cell velocity in lateral wall vessels of the rat cochlea","volume":"52","author":"Quirk","year":"1991","journal-title":"Hear Res"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB34","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/0378-5955(92)90079-3","article-title":"The influence of loud sound on red blood cell velocity and vessel diameter in the cochlea","volume":"63","author":"Quirk","year":"1992","journal-title":"Hear Res"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB35","first-page":"322","article-title":"Cochlear vascular changes in response to loud noise","volume":"16","author":"Quirk","year":"1995","journal-title":"Am J Otol"},{"issue":"11","key":"10.1016\/j.otc.2004.03.005_BIB36","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1001\/archotol.1996.01890230067013","article-title":"Age related differences in cochlear microcirculation and auditory brain stem response","volume":"122","author":"Seidman","year":"1996","journal-title":"Arch Otolaryngol Head Neck Surg"},{"issue":"8","key":"10.1016\/j.otc.2004.03.005_BIB37","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1177\/000348949810700803","article-title":"Age-related changes in cochlear blood flow response to occlusion of anterior inferior cerebellar artery in mice","volume":"107","author":"Suzuki","year":"1998","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB38","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0378-5955(95)00070-K","article-title":"Age-related changes in cochlear vascular conductance in mice","volume":"86","author":"Brown","year":"1995","journal-title":"Hear Res"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-5955(96)00214-6","article-title":"Changes in dorsal cochlear nucleus blood flow during noise exposure","volume":"106","author":"Mandal","year":"1997","journal-title":"Hear Res"},{"issue":"9","key":"10.1016\/j.otc.2004.03.005_BIB40","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1097\/00005537-200209000-00001","article-title":"Enhancing intrinsic cochlear stress defenses to reduce noise induced hearing loss","volume":"112","author":"Kopke","year":"2002","journal-title":"Laryngoscope"},{"issue":"7","key":"10.1016\/j.otc.2004.03.005_BIB41","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1001\/archneur.56.7.796","article-title":"Glucocorticoids in central nervous system bacterial infection","volume":"56","author":"Coyle","year":"1999","journal-title":"Arch Neurol"},{"issue":"9072","key":"10.1016\/j.otc.2004.03.005_BIB42","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/S0140-6736(05)62346-X","article-title":"Prevention of hearing loss from meningitis","volume":"350","author":"Kaplan","year":"1997","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB43","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0194-5998(00)70094-5","article-title":"Dexamethasone pharmacokinetics in the inner ear: comparison of route of administration and use of facilitating agents","volume":"122","author":"Chandrasekhar","year":"2000","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB44","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/S0030-6665(02)00023-3","article-title":"Chemical perfusion of the inner ear","volume":"35","author":"Jackson","year":"2002","journal-title":"Otolaryngol Clin North Am"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB45","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S0194-5998(95)70102-8","article-title":"Guidelines for the diagnosis and evaluation of therapy in Meniere's disease. American Academy of Otolaryngology-Head and Neck Foundation, Inc","volume":"113","author":"Committee on Hearing and Equilibrium","year":"1995","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"11","key":"10.1016\/j.otc.2004.03.005_BIB46","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1097\/00005537-200311000-00008","article-title":"Intratympanic steroids: do they acutely improve hearing in cases of cochlear hydrops?","volume":"113","author":"Hillman","year":"2003","journal-title":"Laryngoscope"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB47","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1016\/S0030-6665(20)30147-X","article-title":"The role of dexamethasone or streptomycin perfusion in the treatment of Meniere's disease","volume":"30","author":"Shea","year":"1997","journal-title":"Otolaryngol Clin North Am"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB48","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1177\/000348940111000203","article-title":"Effects of exposing the opened endolymphatic sac to large doses of steroids to treat intractable Meniere's disease","volume":"110","author":"Kitahara","year":"2001","journal-title":"Ann Otol Rhinol Laryngol"},{"issue":"9","key":"10.1016\/j.otc.2004.03.005_BIB49","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1288\/00005537-199309000-00014","article-title":"Immunoperoxidase study of the endolymphatic sac in Meniere's disease","volume":"103","author":"Dornhoffer","year":"1993","journal-title":"Laryngoscope"},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB50","first-page":"287","article-title":"Immune-status in patients with Meniere's disease","volume":"245","author":"Evans","year":"1988","journal-title":"Arch Otolaryngol"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB51","first-page":"196","article-title":"Dexamethasone inner ear perfusion for the treatment of Meniere's disease: a prospective, randomized, double-blind, crossover trial","volume":"19","author":"Silverstein","year":"1998","journal-title":"Am J Otol"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB52","first-page":"598","article-title":"Free radicals, antioxidants, and human disease: where are we now?","volume":"119","author":"Halliwell","year":"1992","journal-title":"J Lab Clin Med"},{"issue":"7","key":"10.1016\/j.otc.2004.03.005_BIB53","doi-asserted-by":"crossref","first-page":"2029","DOI":"10.1096\/fasebj.5.7.2010056","article-title":"Role of endothelial dysfunction in the pathogenesis of reperfusion injury after myocardial ischemia","volume":"5","author":"Lefer","year":"1991","journal-title":"FASEB J"},{"key":"10.1016\/j.otc.2004.03.005_BIB54","first-page":"153","article-title":"The biology of superoxide and of superoxide dismutase\u2014in brief","volume":"51","author":"Fridovich","year":"1981","journal-title":"Prog Clin Biol Res"},{"key":"10.1016\/j.otc.2004.03.005_BIB55","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/B978-0-12-152827-0.50047-5","article-title":"The glutathione peroxidase reaction: molecular basis of the antioxidant function of selenium in mammals","volume":"27","author":"Flohe","year":"1985","journal-title":"Curr Top Cell Regul"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB56","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/0006-291X(81)90870-6","article-title":"Purification of a new glutathione S-transferase (transferase mu) from human liver having high activity with benzo(alpha)pyrene-4, 5-oxide","volume":"98","author":"Warholm","year":"1981","journal-title":"Biochem Biophys Res Commun"},{"issue":"18","key":"10.1016\/j.otc.2004.03.005_BIB57","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1056\/NEJM198305053081805","article-title":"Hubbard VS. Medical uses of vitamin E","volume":"308","author":"Bieri","year":"1983","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB58","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1159\/000027643","article-title":"Free radicals in the guinea pig inner ear following gentamicin exposure","volume":"61","author":"Takumida","year":"1999","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB59","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0006-8993(97)01156-6","article-title":"Role of glutathione in protection against noise-induced hearing loss","volume":"784","author":"Yamasoba","year":"1998","journal-title":"Brain Res"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB60","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/0378-5955(88)90042-1","article-title":"Effects of cisplatin and thiosulfate upon auditory brainstem responses of guinea pigs","volume":"35","author":"Otto","year":"1988","journal-title":"Hear Res"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB61","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1177\/019459989310900613","article-title":"The protective effects of allopurinol and superoxide dismutase on noise induced cochlear damage","volume":"109","author":"Seidman","year":"1993","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB62","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1046\/j.1523-1755.2000.00437.x","article-title":"Protection from ototoxicity of intraperitoneal gentamicin in guinea pig","volume":"58","author":"Sinswat","year":"2000","journal-title":"Kidney Int"},{"issue":"8","key":"10.1016\/j.otc.2004.03.005_BIB63","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1007\/BF02114761","article-title":"Appearance of free radicals in the guinea pig inner ear after noise-induced acoustic trauma","volume":"252","author":"Yamane","year":"1995","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB64","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1159\/000013847","article-title":"Targeted deletion of the cytosolic Cu\/Zn-superoxide dismutase gene (Sod 1) increases susceptibility to noise induced hearing loss","volume":"4","author":"Ohlemiller","year":"1999","journal-title":"Audiol Neurootol"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB65","doi-asserted-by":"crossref","first-page":"115","DOI":"10.2302\/kjm.46.115","article-title":"Prevention of aminoglycoside induced hearing loss","volume":"46","author":"Sha","year":"1997","journal-title":"Keio J Med"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB66","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1080\/00016480310001484","article-title":"Protective effects of alpha-tocopherol against gentamicin-induced oto-vestibulo toxicity: an experimental study","volume":"123","author":"Fetoni","year":"2003","journal-title":"Acta Otolaryngol"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB67","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1006\/taap.1996.0030","article-title":"Effects of superoxide dismutase and U74389G on acute trimethyltin induced cochlear dysfunction","volume":"136","author":"Clerici","year":"1996","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.otc.2004.03.005_BIB68","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0009-2797(97)00146-4","article-title":"Glutathione: an overview of biosynthesis and modulation","volume":"111\u2013112","author":"Anderson","year":"1998","journal-title":"Chem Biol Interact"},{"issue":"4596","key":"10.1016\/j.otc.2004.03.005_BIB69","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1126\/science.6836290","article-title":"Selective modification of glutathione metabolism","volume":"220","author":"Meister","year":"1983","journal-title":"Science"},{"issue":"22","key":"10.1016\/j.otc.2004.03.005_BIB70","doi-asserted-by":"crossref","first-page":"7130","DOI":"10.1016\/S0021-9258(19)42083-8","article-title":"Glutathione S-transferases. The first enzymatic step in mercapturic acid formation","volume":"249","author":"Habig","year":"1974","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB71","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0925-4439(95)00008-R","article-title":"Influence of metabolic inhibitors on mitochondrial permeability transition and glutathione status","volume":"1271","author":"Reed","year":"1995","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB72","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/0006-2952(94)00474-Z","article-title":"Inhibition of glutathione related enzymes and cytotoxicity of ethacrynic acid and cyclosporine","volume":"49","author":"Hoffman","year":"1995","journal-title":"Biochem Pharmacol"},{"issue":"11","key":"10.1016\/j.otc.2004.03.005_BIB73","doi-asserted-by":"crossref","first-page":"R11","DOI":"10.1016\/0006-2952(90)90077-X","article-title":"Formation of a cytotoxic metabolite from gentamicin by liver","volume":"40","author":"Huang","year":"1990","journal-title":"Biochem Pharmacol"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB74","first-page":"61","article-title":"Specific glutathione-SH inhibition of toxic effects of metabolized gentamicin on isolated guinea pig hair cells","volume":"251","author":"Zenner","year":"1994","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"19","key":"10.1016\/j.otc.2004.03.005_BIB75","doi-asserted-by":"crossref","first-page":"2989","DOI":"10.1016\/0006-2952(84)90598-7","article-title":"The effects of buthionine sulphoximine (BSO) on glutathione depletion and xenobiotic biotransformation","volume":"33","author":"Drew","year":"1984","journal-title":"Biochem Pharmacol"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB76","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1007\/BF02003229","article-title":"Antiinflammatory activity of methionine, methionine sulfoxide and methionine sulfone","volume":"31","author":"Unnikrishnan","year":"1990","journal-title":"Agents Actions"},{"key":"10.1016\/j.otc.2004.03.005_BIB77","series-title":"Data for biochemical research","first-page":"409","article-title":"Metal binding properties of compounds used in biochemistry","author":"Dawson","year":"1986"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB78","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/S0378-5955(00)00003-4","article-title":"Antioxidants attenuate gentamicin-induced free radical formation in vitro and ototoxicity in vivo: D-methionine is a potential protectant","volume":"142","author":"Sha","year":"2000","journal-title":"Hear Res"},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB79","first-page":"559","article-title":"Use of organotypic cultures of Corti's organ to study the protective effects of antioxidant molecules on cisplatin induced damage of auditory hair cells","volume":"18","author":"Kopke","year":"1997","journal-title":"Am J Otol"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB80","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S0378-5955(96)00152-9","article-title":"D-methionine provides excellent protection from cisplatin ototoxicity in the rat","volume":"102","author":"Campbell","year":"1996","journal-title":"Hear Res"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB81","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/S0161-813X(00)00010-3","article-title":"Round window membrane delivery of L-methionine provides protection from cisplatin ototoxicity without compromising chemotherapeutic efficacy","volume":"22","author":"Li","year":"2001","journal-title":"Neurotoxicology"},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB82","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000013890","article-title":"D-methionine attenuates inner hair cell loss in carboplatin-treated chinchillas","volume":"5","author":"Lockwood","year":"2000","journal-title":"Audiol Neurootol"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB83","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00129492-200401000-00007","article-title":"Round window application of D-methionine, sodium thiosulfate, brain-derived neurotrophic factor, and fibroblast growth factor-2 in cisplatin-induced ototoxicity","volume":"25","author":"Wimmer","year":"2004","journal-title":"Otol Neurotol"},{"key":"10.1016\/j.otc.2004.03.005_BIB84","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0009-2797(97)00146-4","article-title":"Glutathione: an overview of biosynthesis and modulation","volume":"111\u2013112","author":"Anderson","year":"1998","journal-title":"Chem Biol Interact"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB85","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0163-7258(91)90076-X","article-title":"Glutathione deficiency produced by inhibition of its synthesis, and its reversal; applications in research and therapy","volume":"51","author":"Meister","year":"1991","journal-title":"Pharmacol Ther"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB86","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0378-5955(00)00176-3","article-title":"Reduction of noise-induced hearing loss using L-NAC and salicylate in the chinchilla","volume":"149","author":"Kopke","year":"2000","journal-title":"Hear Res"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB87","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1002\/ana.10684","article-title":"Meningitis-associated hearing loss: protection by adjunctive antioxidant therapy","volume":"54","author":"Klein","year":"2003","journal-title":"Ann Neurol"},{"issue":"9","key":"10.1016\/j.otc.2004.03.005_BIB88","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/S0006-2952(96)00820-9","article-title":"Resveratrol inhibits metal ion-dependent and independent peroxidation of porcine low-density lipoproteins","volume":"53","author":"Belguendouz","year":"1997","journal-title":"Biochem Pharmacol"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB89","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1097\/00001756-199704140-00035","article-title":"Amelioration of oxidative stress by antioxidants and resveratrol in PC12 cells","volume":"8","author":"Chanvitayapongs","year":"1997","journal-title":"Neuroreport"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB90","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/0009-8981(95)06045-1","article-title":"The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease","volume":"235","author":"Pace-Asciak","year":"1995","journal-title":"Clin Chim Acta"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB91","first-page":"1","article-title":"Antiplatelet activity of synthetic and natural resveratrol in red wine","volume":"17","author":"Bertelli","year":"1995","journal-title":"Int J Tissue React"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB92","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/0306-3623(95)02001-2","article-title":"Vasorelaxing activity of resveratrol and quercetin in isolated rat aorta","volume":"27","author":"Chen","year":"1996","journal-title":"Gen Pharmacol"},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB93","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/S0194-5998(03)01586-9","article-title":"Effects of resveratrol on acoustic trauma","volume":"129","author":"Seidman","year":"2003","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB94","first-page":"1598","article-title":"Endothelial activation by hydrogen peroxide. Selective increases of intercellular adhesion molecule-1 and major histocompatibility complex class I","volume":"142","author":"Bradley","year":"1993","journal-title":"Am J Pathol"},{"issue":"Pt2","key":"10.1016\/j.otc.2004.03.005_BIB95","first-page":"H1833","article-title":"Reactive oxidants mediate TNF-alpha-induced leukocyte adhesion to rat mesenteric venular endothelium","volume":"269","author":"Morita","year":"1995","journal-title":"Am J Physiol"},{"key":"10.1016\/j.otc.2004.03.005_BIB96","doi-asserted-by":"crossref","first-page":"10754","DOI":"10.1103\/PhysRevB.42.10754","article-title":"Localized moment in Mn-doped gamma-TiAl alloys","volume":"42","author":"Coletti","year":"1990","journal-title":"Phys Rev B Condens Matter"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB97","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1111\/j.1471-4159.1992.tb09324.x","article-title":"Induction of interleukin-1 beta mRNA in rat brain after transient forebrain ischemia","volume":"58","author":"Minami","year":"1992","journal-title":"J Neurochem"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB98","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1172\/JCI116122","article-title":"Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface","volume":"90","author":"Shreeniwas","year":"1992","journal-title":"J Clin Invest"},{"issue":"Pt1","key":"10.1016\/j.otc.2004.03.005_BIB99","first-page":"599","article-title":"Ischemic injury induces altered MHC gene expression in kidney by an interferon-gamma-dependent pathway","volume":"23","author":"Shoskes","year":"1991","journal-title":"Transplant Proc"},{"key":"10.1016\/j.otc.2004.03.005_BIB100","first-page":"200","article-title":"Treatment of inflammatory diseases with a monoclonal antibody to intercellular adhesion molecules 1","volume":"189","author":"Rothlein","year":"1995","journal-title":"Ciba Found Symp"},{"key":"10.1016\/j.otc.2004.03.005_BIB101","first-page":"159","article-title":"Adhesion molecules and acute renal failure","volume":"25","author":"Bonventre","year":"1996","journal-title":"Adv Nephrol Necker Hosp"},{"key":"10.1016\/j.otc.2004.03.005_BIB102","unstructured":"Tang W, Seidman MD, Bai U, et al. The effect of anti-intercellular adhesion molecule-1 antibody on noise-induced cochlear damage. Presented at the 23rd Annual Midwinter Research Meeting for Research in Otolaryngology. St. Petersburg (FL), February 20\u201324, 2000."},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB103","first-page":"530","article-title":"Mitochondrial role in hair cell survival after injury","volume":"113","author":"Hyde","year":"1995","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB104","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1097\/00005537-199606000-00021","article-title":"Association of mitochondrial DNA deletions and cochlear pathology: a molecular biologic tool","volume":"106","author":"Seidman","year":"1996","journal-title":"Laryngoscope"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB105","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0196-0709(00)80003-4","article-title":"Biologic activity of mitochondrial metabolites on aging and age related hearing loss","volume":"21","author":"Seidman","year":"2000","journal-title":"Am J Otol"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB106","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1067\/mhn.2002.127627","article-title":"Influence of lecithin on mitochondrial DNA and age related hearing loss","volume":"127","author":"Seidman","year":"2002","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"10","key":"10.1016\/j.otc.2004.03.005_BIB107","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S0300-9084(00)88881-1","article-title":"Aging and mitochondria","volume":"80","author":"Gadaleta","year":"1998","journal-title":"Biochimie"},{"issue":"23","key":"10.1016\/j.otc.2004.03.005_BIB108","doi-asserted-by":"crossref","first-page":"10771","DOI":"10.1073\/pnas.91.23.10771","article-title":"Oxidative damage and mitochondrial decay in aging","volume":"91","author":"Shigenaga","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB109","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0378-5955(98)00195-6","article-title":"Attenuation of aminoglycoside-induced cochlear damage with the metabolic antioxidant alpha-lipoic acid","volume":"128","author":"Conlon","year":"1999","journal-title":"Hear Res"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB110","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1080\/000164800750000568","article-title":"Glutamate is the afferent neurotransmitter in the human cochlea","volume":"120","author":"Nordang","year":"2000","journal-title":"Acta Otolaryngol"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB111","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/ana.410190202","article-title":"Glutamate and the pathophysiology of hypoxic-ischemic brain damage","volume":"19","author":"Rothman","year":"1986","journal-title":"Ann Neurol"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB112","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0166-2236(95)93869-Y","article-title":"Excitotoxicity and the NMDA receptor\u2014still lethal after eight years","volume":"18","author":"Rothman","year":"1995","journal-title":"Trends Neurosci"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB113","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0378-5955(02)00484-7","article-title":"Protection and treatment of sensorineural hearing disorders caused by exogenous factors: experimental findings and potential clinical applications","volume":"169","author":"Duan","year":"2002","journal-title":"Hear Res"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB114","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s004050050218","article-title":"Effects of kynurenic acid as a glutamate receptor antagonist in the guinea pig","volume":"257","author":"Khan","year":"2000","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"12","key":"10.1016\/j.otc.2004.03.005_BIB115","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1038\/nm1296-1338","article-title":"N-methyl-D-aspartate antagonists limit aminoglycoside antibiotic-induced hearing loss","volume":"2","author":"Basile","year":"1996","journal-title":"Nat Med"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB116","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/S0378-5955(01)00228-3","article-title":"NMDA receptor blockage protects against permanent noise-induced hearing loss but not its potentiation by carbon monoxide","volume":"154","author":"Chen","year":"2001","journal-title":"Hear Res"},{"issue":"13","key":"10.1016\/j.otc.2004.03.005_BIB117","doi-asserted-by":"crossref","first-page":"7597","DOI":"10.1073\/pnas.97.13.7597","article-title":"Complementary roles of neurotrophin 3 and a N-methyl-D-aspartate antagonist in the protection of noise and aminoglycoside-induced ototoxicity","volume":"97","author":"Duan","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB118","doi-asserted-by":"crossref","first-page":"90","DOI":"10.3171\/jns.2000.93.1.0090","article-title":"Effectiveness of preoperative administration of an N-methyl-D-aspartate antagonist to enhance cochlear neuron resistance to intraoperative traumatic stress: an experimental study","volume":"93","author":"Sekiya","year":"2000","journal-title":"J Neurosurg"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB119","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1080\/00016489950181611","article-title":"New approaches for inner ear therapy with glutamate antagonists","volume":"119","author":"Oestreicher","year":"1999","journal-title":"Acta Otlaryngol"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB120","doi-asserted-by":"crossref","first-page":"825","DOI":"10.3109\/00016489709114208","article-title":"Caroverine in tinnitus treatment. A placebo contolled blind study","volume":"117","author":"Denk","year":"1997","journal-title":"Acta Otolaryngol"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB121","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/0196-0709(94)90036-1","article-title":"Oral magnesium intake reduces permanent hearing loss induced by noise exposure","volume":"15","author":"Attias","year":"1994","journal-title":"Am J Otolaryngol"},{"issue":"8","key":"10.1016\/j.otc.2004.03.005_BIB122","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1080\/00016480310000638","article-title":"Acute treatment of noise trauma with local caroverine application in the guinea pig","volume":"123","author":"Chen","year":"2003","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.otc.2004.03.005_BIB123","series-title":"Scientific basis of noise-induced hearing loss","first-page":"36","article-title":"Excitotoxicity and plasticity of IHC-auditory nerve contributes to both temporary and permanent threshold shift","author":"Puel","year":"1996"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB124","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0306-4522(91)90103-U","article-title":"Alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid electrophysiological and neurotoxic effects in the guinea-pig cochlea","volume":"45","author":"Puel","year":"1991","journal-title":"Neuroscience"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB125","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0378-5955(85)90006-1","article-title":"Kainic acid selectively alters auditory dendrites connected with cochlear inner hair cells","volume":"18","author":"Pujol","year":"1985","journal-title":"Hear Res"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB126","first-page":"241","article-title":"Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity","volume":"341","author":"Puel","year":"1994","journal-title":"Neuroscience"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB127","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1089\/neu.1997.14.121","article-title":"Mechanism of calpain proteolysis following traumatic brain injury: implications for pathology and therapy: a review and update","volume":"14","author":"Kampfl","year":"1997","journal-title":"J Neurotrauma"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB128","first-page":"4","article-title":"The effects on leupeptin on cochlear blood flow, auditory sensitivity, and histology","volume":"7","author":"Tang","year":"2001","journal-title":"Int Tinnitus J"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB129","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0301-0082(84)90012-1","article-title":"Calcium-activated neutral protease (CANP) in brain and other tissues","volume":"23","author":"Zimmerman","year":"1984","journal-title":"Prog Neurobiol"},{"issue":"7","key":"10.1016\/j.otc.2004.03.005_BIB130","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1073\/pnas.90.7.2628","article-title":"Widespread activation of calcium-activated neutral proteinase (calpain) in the brain in Alzheimer disease: a potential molecular basis for neuronal degeneration","volume":"90","author":"Saito","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.otc.2004.03.005_BIB131","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1749-6632.1998.tb08228.x","article-title":"Role of calpain in spinal cord injury: effects of calpain and free radical inhibitors","volume":"844","author":"Banik","year":"1998","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.otc.2004.03.005_BIB132","unstructured":"Faddis BT, Hughes RM. Activation of the neutral cysteine protease, calpain, during cochlear injury. Presented at a poster session at the 21st Annual Midwinter Research Meeting of the Association for Research in Otolaryngology. St. Petersburg (FL), February 15\u201319, 1998."},{"key":"10.1016\/j.otc.2004.03.005_BIB133","unstructured":"Nishimoto SY, Hughes RM, Faddis BT. Activation of calpain in the cochlea following noise exposure. Presented at a poster session during the 22nd Annual Midwinter Research Meeting of the Association for Research in Otolaryngology. St. Petersburg (FL), February 13\u201318, 1999."},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB134","first-page":"71","article-title":"Calpain inhibitors as neuroprotective agents in neurodegenerative disorders","volume":"3","author":"Stracher","year":"1997","journal-title":"Int Tinnitus J"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB135","first-page":"134","article-title":"Noise, calpain, calpain inhibitors, and neuroprotection: a preliminary report of tinnitus control","volume":"4","author":"Shulman","year":"1998","journal-title":"Int Tinnitus J"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB136","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/s101620020004","article-title":"Calpain immunoreactivity and morphological damage in chinchilla inner ears after carboplatin","volume":"3","author":"Ding","year":"2002","journal-title":"J Assoc Res Otolaryngol"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB137","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/S0006-8993(99)01983-6","article-title":"Calpain inhibitors protect auditory sensory cells from hypoxia and neurotrophin-withdrawal induced apoptosis","volume":"850","author":"Cheng","year":"1999","journal-title":"Brain Res"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB138","first-page":"11","article-title":"protecting inner ear from acoustic trauma","volume":"4","author":"Salvi","year":"1998","journal-title":"Int Tinnitus J"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB139","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0378-5955(01)00417-8","article-title":"Leupeptin protects cochlear and vestibular hair cells from gentamicin ototoxicity","volume":"164","author":"Ding","year":"2002","journal-title":"Hear Res"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB140","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/S0959-4388(98)80035-4","article-title":"Factors controlling hair-cell regeneration\/repair in the inner ear","volume":"8","author":"Staecker","year":"1998","journal-title":"Curr Opin Neurobiol"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB141","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1080\/000164800750000784","article-title":"Epidermal growth factor upregulates production of supernumerary hair cells in neonatal rat organ of Corti explants","volume":"120","author":"Lefebvre","year":"2000","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.otc.2004.03.005_BIB142","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1111\/j.1749-6632.1999.tb08651.x","article-title":"Role of neurotrophins and lectins in prevention of ototoxicity","volume":"884","author":"Gao","year":"1999","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.otc.2004.03.005_BIB143","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1111\/j.1749-6632.1999.tb08650.x","article-title":"Rescue and regrowth of sensory nerves following differentiation by neurotrophic factors","volume":"884","author":"Altschuler","year":"1999","journal-title":"Ann N Y Acad Sci"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB144","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1038\/nm0496-463","article-title":"Protection of auditory neurons from aminoglycoside toxicity by neurotrophin-3","volume":"2","author":"Ernfors","year":"1996","journal-title":"Nat Med"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB145","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0378-5955(98)00095-1","article-title":"Guinea pig auditory neurons are protected by glial cell line-derived growth factor from degeneration after noise","volume":"124","author":"Ylikoski","year":"1998","journal-title":"Hear Res"},{"issue":"10","key":"10.1016\/j.otc.2004.03.005_BIB146","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1097\/00001756-199907130-00014","article-title":"Effects of BDNF and NT-3 on hair cell survival in guinea pig cochlea damaged by kanamycin treatment","volume":"10","author":"Ruan","year":"1999","journal-title":"Neuroreport"},{"issue":"10","key":"10.1016\/j.otc.2004.03.005_BIB147","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1097\/00001756-199807130-00007","article-title":"GDNF protects the cochlea against noise damage","volume":"9","author":"Keithley","year":"1998","journal-title":"Neuroreport"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB148","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/S0378-5955(00)00007-1","article-title":"Glial cell line-derived neurotrophic factor has a dose dependent influence on noise induced hearing loss in the guinea pig cochlea","volume":"142","author":"Shoji","year":"2000","journal-title":"Hear Res"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB149","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0378-5955(00)00106-4","article-title":"Differential protective effects of neurotrophins in the attenuation of noise-induced hair cell loss","volume":"146","author":"Shoji","year":"2000","journal-title":"Hear Res"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB150","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1159\/000072253","article-title":"Comparison of the protective efficacy of neurotrophins and antioxidants for vibration-induced trauma","volume":"65","author":"Zou","year":"2003","journal-title":"ORL J Otorhinolaryngol Relat Spec"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB151","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1073\/pnas.032677999","article-title":"Neurotrophic factor intervention restores auditory function in deafened animals","volume":"99","author":"Shinohara","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.otc.2004.03.005_BIB152","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1749-6632.1999.tb08653.x","article-title":"Gene therapy in the inner ear. Mechanisms and clinical implications","volume":"884","author":"Van de Water","year":"1999","journal-title":"Ann N Y Acad Sci"},{"issue":"2","key":"10.1016\/j.otc.2004.03.005_BIB153","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ymthe.2003.11.020","article-title":"Antioxidant gene therapy can protect hearing and hair cells from ototoxicity","volume":"9","author":"Kawamoto","year":"2004","journal-title":"Mol Ther"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB154","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/S1525-0016(03)00058-3","article-title":"Hearing and hair cells are protected by adenoviral gene therapy with TGF-beta1 and GDNF","volume":"7","author":"Kawamoto","year":"2003","journal-title":"Mol Ther"},{"issue":"5","key":"10.1016\/j.otc.2004.03.005_BIB155","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/sj.gt.3301917","article-title":"Adenovirus-mediated overexpression of a gene prevents hearing loss and progressive inner hair cell loss after transient cochlear ischemia in gerbils","volume":"10","author":"Hakuba","year":"2003","journal-title":"Gene Ther"},{"issue":"10","key":"10.1016\/j.otc.2004.03.005_BIB156","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1097\/00001756-200207190-00016","article-title":"Adenoviral and adeno-associated viral vector mediated gene transfer in the guinea pig cochlea","volume":"13","author":"Li Duan","year":"2002","journal-title":"Neuroreport"},{"issue":"4","key":"10.1016\/j.otc.2004.03.005_BIB157","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s101620010011","article-title":"Spiral ganglion neurons are protected from degeneration by GDNF gene therapy","volume":"1","author":"Yagi","year":"2000","journal-title":"J Assoc Res Otolaryngol"},{"issue":"12","key":"10.1016\/j.otc.2004.03.005_BIB158","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1038\/sj.gt.3301180","article-title":"Effect of transgenic GDNF expression on gentamicin-induced cochlear and vestibular toxicity","volume":"7","author":"Suzuki","year":"2000","journal-title":"Gene Ther"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB159","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0378-5955(98)00196-8","article-title":"Cationic liposome mediated transgene expression in the guinea pig cochlea","volume":"128","author":"Wareing","year":"1999","journal-title":"Hear Res"},{"issue":"1\u20132","key":"10.1016\/j.otc.2004.03.005_BIB160","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0378-5955(00)00216-1","article-title":"A surgical approach appropriate for targeted cochlear gene therapy in the mouse","volume":"151","author":"Jero","year":"2001","journal-title":"Hear Res"},{"issue":"3","key":"10.1016\/j.otc.2004.03.005_BIB161","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1002\/cne.10480","article-title":"Glial cell line-derived neurotrophic factor and chronic electrical stimulation prevent VIII cranial nerve degeneration following denervation","volume":"454","author":"Kanzaki","year":"2002","journal-title":"J Comp Neurol"},{"issue":"11","key":"10.1016\/j.otc.2004.03.005_BIB162","doi-asserted-by":"crossref","first-page":"4395","DOI":"10.1523\/JNEUROSCI.23-11-04395.2003","article-title":"Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo","volume":"23","author":"Kawamoto","year":"2003","journal-title":"J Neurosci"},{"issue":"6","key":"10.1016\/j.otc.2004.03.005_BIB163","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1006\/mthe.2001.0334","article-title":"HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage","volume":"3","author":"Chen","year":"2001","journal-title":"Mol Ther"},{"issue":"1","key":"10.1016\/j.otc.2004.03.005_BIB164","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1006\/mthe.2002.0627","article-title":"Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea","volume":"6","author":"Bowers","year":"2002","journal-title":"Mol Ther"}],"container-title":["Otolaryngologic Clinics of North America"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666504000830?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0030666504000830?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,1,24]],"date-time":"2024-01-24T23:44:42Z","timestamp":1706139882000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0030666504000830"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,10]]},"references-count":164,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,10]]}},"alternative-id":["S0030666504000830"],"URL":"https:\/\/doi.org\/10.1016\/j.otc.2004.03.005","relation":{},"ISSN":["0030-6665"],"issn-type":[{"value":"0030-6665","type":"print"}],"subject":[],"published":{"date-parts":[[2004,10]]}}}